7WUI
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![BU of 7wui by Molmil](/molmil-images/mine/7wui) | Tethered peptide activation mechanism of adhesion GPCRs ADGRG2 and ADGRG4 | 分子名称: | Adhesion G-protein coupled receptor G2,mCherry, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Guo, S.C, He, Q.T, Xiao, P, Sun, J.P, Yu, X. | 登録日 | 2022-02-08 | 公開日 | 2022-04-27 | 最終更新日 | 2022-05-11 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4. Nature, 604, 2022
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7WUQ
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![BU of 7wuq by Molmil](/molmil-images/mine/7wuq) | Tethered peptide activation mechanism of adhesion GPCRs ADGRG2 and ADGRG4 | 分子名称: | Adhesion G-protein coupled receptor G2,mCherry, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | He, Q.T, Guo, S.C, Xiao, P, Sun, J.P, Yu, X, Gou, L, Kong, L.L, Zhang, L. | 登録日 | 2022-02-09 | 公開日 | 2022-04-27 | 最終更新日 | 2022-05-11 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4. Nature, 604, 2022
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7WUJ
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![BU of 7wuj by Molmil](/molmil-images/mine/7wuj) | Tethered peptide activation mechanism of adhesion GPCRs ADGRG2 and ADGRG4 | 分子名称: | Adhesion G-protein coupled receptor G4,Uncharacterized protein, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Guo, S.C, Huang, S.M, He, Q.T, Xiao, P, Sun, J.P, Yu, X. | 登録日 | 2022-02-08 | 公開日 | 2022-04-27 | 最終更新日 | 2022-05-11 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4. Nature, 604, 2022
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5W9S
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![BU of 5w9s by Molmil](/molmil-images/mine/5w9s) | Zinc finger of human CXXC5 in complex with CpG DNA | 分子名称: | CXXC-type zinc finger protein 5, CpG DNA fragment, SULFATE ION, ... | 著者 | Liu, K, Xu, C, Tempel, W, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2017-06-23 | 公開日 | 2017-10-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants. Structure, 26, 2018
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8K2D
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![BU of 8k2d by Molmil](/molmil-images/mine/8k2d) | Cryo-EM structure of the yeast 80S ribosome with tigecycline, eEF2, Stm1 and eIF5A | 分子名称: | 18S rRNA, 23S rRNA, 40S ribosomal protein S1-A, ... | 著者 | Buschauer, R, Beckmann, R, Cheng, J. | 登録日 | 2023-07-12 | 公開日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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3EPZ
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![BU of 3epz by Molmil](/molmil-images/mine/3epz) | Structure of the replication foci-targeting sequence of human DNA cytosine methyltransferase DNMT1 | 分子名称: | DNA (cytosine-5)-methyltransferase 1, GLYCEROL, SODIUM ION, ... | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2008-09-30 | 公開日 | 2008-11-25 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | The replication focus targeting sequence (RFTS) domain is a DNA-competitive inhibitor of Dnmt1. J.Biol.Chem., 286, 2011
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7Y3A
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![BU of 7y3a by Molmil](/molmil-images/mine/7y3a) | Crystal structure of TRIM7 bound to 2C | 分子名称: | E3 ubiquitin-protein ligase TRIM7,E3 ubiquitin-protein ligase TRIM7,E3 ubiquitin-protein ligase TRIM7,TRIM7-2C | 著者 | Dong, C, Yan, X. | 登録日 | 2022-06-10 | 公開日 | 2022-08-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7. Proc.Natl.Acad.Sci.USA, 119, 2022
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7Y3B
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![BU of 7y3b by Molmil](/molmil-images/mine/7y3b) | Crystal structure of TRIM7 bound to GN1 | 分子名称: | E3 ubiquitin-protein ligase TRIM7,TRIM7-GN1 | 著者 | Dong, C, Yan, X. | 登録日 | 2022-06-10 | 公開日 | 2022-08-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7. Proc.Natl.Acad.Sci.USA, 119, 2022
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7Y3C
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![BU of 7y3c by Molmil](/molmil-images/mine/7y3c) | Crystal structure of TRIM7 bound to RACO-1 | 分子名称: | E3 ubiquitin-protein ligase TRIM7,E3 ubiquitin-protein ligase TRIM7,TRIM7-RACO-1 | 著者 | Dong, C, Yan, X. | 登録日 | 2022-06-10 | 公開日 | 2022-08-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7. Proc.Natl.Acad.Sci.USA, 119, 2022
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2PYE
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![BU of 2pye by Molmil](/molmil-images/mine/2pye) | Crystal Structures of High Affinity Human T-Cell Receptors Bound to pMHC RevealNative Diagonal Binding Geometry TCR Clone C5C1 Complexed with MHC | 分子名称: | 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, Beta-2-microglobulin, Cancer/testis antigen 1B, ... | 著者 | Sami, M, Rizkallah, P.J, Dunn, S, Li, Y, Moysey, R, Vuidepot, A, Baston, E, Todorov, P, Molloy, P, Gao, F, Boulter, J.M, Jakobsen, B.K. | 登録日 | 2007-05-16 | 公開日 | 2007-09-25 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structures of high affinity human T-cell receptors bound to peptide major
histocompatibility complex reveal native diagonal binding geometry Protein Eng.Des.Sel., 20, 2007
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7ESV
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![BU of 7esv by Molmil](/molmil-images/mine/7esv) | |
7ESQ
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![BU of 7esq by Molmil](/molmil-images/mine/7esq) | |
7ESP
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![BU of 7esp by Molmil](/molmil-images/mine/7esp) | |
7ESO
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![BU of 7eso by Molmil](/molmil-images/mine/7eso) | |
7CE8
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![BU of 7ce8 by Molmil](/molmil-images/mine/7ce8) | Crystal structure of T2R-TTL-Compound11 complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ... | 著者 | Chen, L.J, Chen, Q, Yu, Y, Yang, J.H. | 登録日 | 2020-06-22 | 公開日 | 2021-06-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.725 Å) | 主引用文献 | Small Molecules Promote Selective Denaturation and Degradation of Tubulin Heterodimers through a Low-Barrier Hydrogen Bond. J.Med.Chem., 65, 2022
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5ZZ8
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![BU of 5zz8 by Molmil](/molmil-images/mine/5zz8) | Structure of the Herpes simplex virus type 2 C-capsid with capsid-vertex-specific component | 分子名称: | Major capsid protein, UL17, UL25, ... | 著者 | Wang, J.L, Yuan, S, Zhu, D.J, Tang, H, Wang, N, Chen, W.Y, Gao, Q, Li, Y.H, Wang, J.Z, Liu, H.R, Zhang, X.Z, Rao, Z.H, Wang, X.X. | 登録日 | 2018-05-31 | 公開日 | 2018-10-10 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | 主引用文献 | Structure of the herpes simplex virus type 2 C-capsid with capsid-vertex-specific component. Nat Commun, 9, 2018
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6LID
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![BU of 6lid by Molmil](/molmil-images/mine/6lid) | Heteromeric amino acid transporter b0,+AT-rBAT complex | 分子名称: | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Yan, R.H, Li, Y.N, Lei, J.L, Zhou, Q. | 登録日 | 2019-12-10 | 公開日 | 2020-04-29 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Cryo-EM structure of the human heteromeric amino acid transporter b0,+AT-rBAT. Sci Adv, 6, 2020
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6LI9
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![BU of 6li9 by Molmil](/molmil-images/mine/6li9) | Heteromeric amino acid transporter b0,+AT-rBAT complex bound with Arginine | 分子名称: | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ARGININE, ... | 著者 | Yan, R.H, Li, Y.N, Lei, J.L, Zhou, Q. | 登録日 | 2019-12-10 | 公開日 | 2020-04-29 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Cryo-EM structure of the human heteromeric amino acid transporter b0,+AT-rBAT. Sci Adv, 6, 2020
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5Z0Q
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![BU of 5z0q by Molmil](/molmil-images/mine/5z0q) | Crystal Structure of OvoB | 分子名称: | Aminotransferase, class I and II, PYRIDOXAL-5'-PHOSPHATE | 著者 | Cai, Y.J, Huang, P, Wu, L, Zhou, J.H, Liu, P.H. | 登録日 | 2017-12-20 | 公開日 | 2018-11-07 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | 主引用文献 | In Vitro Reconstitution of the Remaining Steps in Ovothiol A Biosynthesis: C-S Lyase and Methyltransferase Reactions. Org. Lett., 20, 2018
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1K94
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![BU of 1k94 by Molmil](/molmil-images/mine/1k94) | Crystal structure of des(1-52)grancalcin with bound calcium | 分子名称: | CALCIUM ION, GRANCALCIN | 著者 | Jia, J, Borregaard, N, Lollike, K, Cygler, M. | 登録日 | 2001-10-26 | 公開日 | 2001-12-07 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of Ca(2+)-loaded human grancalcin. Acta Crystallogr.,Sect.D, 57, 2001
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1K95
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![BU of 1k95 by Molmil](/molmil-images/mine/1k95) | Crystal structure of des(1-52)grancalcin with bound calcium | 分子名称: | GRANCALCIN | 著者 | Jia, J, Borregaard, N, Lollike, K, Cygler, M. | 登録日 | 2001-10-26 | 公開日 | 2001-12-07 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of Ca(2+)-loaded human grancalcin. Acta Crystallogr.,Sect.D, 57, 2001
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7K9X
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7E5Y
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![BU of 7e5y by Molmil](/molmil-images/mine/7e5y) | Molecular basis for neutralizing antibody 2B11 targeting SARS-CoV-2 RBD | 分子名称: | 2B11 Fab Heavy chain, 2B11 Fab Light chain, Spike protein S1 | 著者 | Wu, H, Yu, F, Wang, Q.S, Zhou, H, Wang, W.W, Zhao, T, Pan, Y.B, Yang, X.M. | 登録日 | 2021-02-21 | 公開日 | 2021-06-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.59 Å) | 主引用文献 | Screening of potent neutralizing antibodies against SARS-CoV-2 using convalescent patients-derived phage-display libraries. Cell Discov, 7, 2021
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5YF4
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![BU of 5yf4 by Molmil](/molmil-images/mine/5yf4) | A kinase complex MST4-MOB4 | 分子名称: | MOB-like protein phocein, Peptide from Serine/threonine-protein kinase 26, ZINC ION | 著者 | Chen, M, Zhou, Z.C. | 登録日 | 2017-09-20 | 公開日 | 2018-08-15 | 最終更新日 | 2018-09-26 | 実験手法 | X-RAY DIFFRACTION (1.897 Å) | 主引用文献 | The MST4-MOB4 complex disrupts the MST1-MOB1 complex in the Hippo-YAP pathway and plays a pro-oncogenic role in pancreatic cancer. J. Biol. Chem., 293, 2018
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7D0C
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![BU of 7d0c by Molmil](/molmil-images/mine/7d0c) | S protein of SARS-CoV-2 in complex bound with P5A-3A1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of P5A-3A1, ... | 著者 | Yan, R.H, Wang, R.K, Yu, J.F, Zhang, Y.Y, Liu, N, Wang, H.W, Wang, X.Q, Zhang, L.Q, Zhou, Q. | 登録日 | 2020-09-09 | 公開日 | 2021-03-10 | 最終更新日 | 2021-05-19 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies. Cell Res., 31, 2021
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