2FZH
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![BU of 2fzh by Molmil](/molmil-images/mine/2fzh) | New Insights into Dihydrofolate Reductase Interactions: Analysis of Pneumocystis carinii and Mouse DHFR Complexes with NADPH and Two Highly Potent Trimethoprim Derivatives | 分子名称: | 2,4-DIAMINO-5-[2-METHOXY-5-(4-CARBOXYBUTYLOXY)BENZYL]PYRIMIDINE, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Cody, V, Pace, J, Chisum, K, Rosowsky, A. | 登録日 | 2006-02-09 | 公開日 | 2006-12-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | New insights into DHFR interactions: analysis of Pneumocystis carinii and mouse DHFR complexes with NADPH and two highly potent 5-(omega-carboxy(alkyloxy) trimethoprim derivatives reveals conformational correlations with activity and novel parallel ring stacking interactions. Proteins, 65, 2006
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2G3J
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![BU of 2g3j by Molmil](/molmil-images/mine/2g3j) | Structure of S.olivaceoviridis xylanase Q88A/R275A mutant | 分子名称: | PHOSPHATE ION, Xylanase, alpha-D-xylopyranose-(1-4)-alpha-D-xylopyranose | 著者 | Diertavitian, S, Kaneko, S, Fujimoto, Z, Kuno, A, Johansson, E, Lo Leggio, L. | 登録日 | 2006-02-20 | 公開日 | 2007-03-06 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure-based engineering of glucose specificity in a family 10 xylanase from Streptomyces olivaceoviridis E-86 PROCESS BIOCHEM, 47, 2012
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2FOD
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![BU of 2fod by Molmil](/molmil-images/mine/2fod) | Structure of porcine pancreatic elastase in 80% ethanol | 分子名称: | CALCIUM ION, ETHANOL, SULFATE ION, ... | 著者 | Mattos, C, Bellamacina, C.R, Peisach, E, Pereira, A, Vitkup, D, Petsko, G.A, Ringe, D. | 登録日 | 2006-01-13 | 公開日 | 2006-04-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Multiple solvent crystal structures: Probing binding sites, plasticity and hydration J.Mol.Biol., 357, 2006
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2FOM
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![BU of 2fom by Molmil](/molmil-images/mine/2fom) | Dengue Virus NS2B/NS3 Protease | 分子名称: | CHLORIDE ION, GLYCEROL, polyprotein | 著者 | Schiering, N, Kroemer, M, Renatus, M, Erbel, P, D'Arcy, A. | 登録日 | 2006-01-13 | 公開日 | 2006-03-07 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural basis for the activation of flaviviral NS3 proteases from dengue and West Nile virus. Nat.Struct.Mol.Biol., 13, 2006
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2FSW
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![BU of 2fsw by Molmil](/molmil-images/mine/2fsw) | Crystal Structure of the Putative Transcriptional Regualator, MarR family from Porphyromonas gingivalis W83 | 分子名称: | PG_0823 protein | 著者 | Kim, Y, Quartey, P, Buelt, J, Moy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2006-01-23 | 公開日 | 2006-03-07 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Transcriptional Regualator, MarR family from Porphyromonas gingivalis W83 To be Published
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2FWF
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![BU of 2fwf by Molmil](/molmil-images/mine/2fwf) | high resolution crystal structure of the C-terminal domain of the electron transfer catalyst DsbD (reduced form) | 分子名称: | IODIDE ION, SODIUM ION, Thiol:disulfide interchange protein dsbD | 著者 | Stirnimann, C.U, Rozhkova, A, Grauschopf, U, Boeckmann, R.A, Glockshuber, R, Capitani, G, Gruetter, M.G. | 登録日 | 2006-02-02 | 公開日 | 2006-06-13 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | High-resolution structures of Escherichia coli cDsbD in different redox states: A combined crystallographic, biochemical and computational study J.Mol.Biol., 358, 2006
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2FUM
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![BU of 2fum by Molmil](/molmil-images/mine/2fum) | Catalytic domain of protein kinase PknB from Mycobacterium tuberculosis in complex with mitoxantrone | 分子名称: | 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE, Probable serine/threonine-protein kinase pknB | 著者 | Wehenkel, A, Alzari, P.M. | 登録日 | 2006-01-27 | 公開日 | 2006-08-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | The structure of PknB in complex with mitoxantrone, an ATP-competitive inhibitor, suggests a mode of protein kinase regulation in mycobacteria Febs Lett., 580, 2006
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2FNC
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2FQ4
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![BU of 2fq4 by Molmil](/molmil-images/mine/2fq4) | The crystal structure of the transcriptional regulator (TetR family) from Bacillus cereus | 分子名称: | Transcriptional regulator, TetR family | 著者 | Zhang, R, Wu, R, Moy, S, Cymborowski, M, Minor, W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2006-01-17 | 公開日 | 2006-02-28 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | The crystal structure of the transcriptional regulator (TetR family) from Bacillus cereus To be Published
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2FOE
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![BU of 2foe by Molmil](/molmil-images/mine/2foe) | Structure of porcine pancreatic elastase in 80% hexane | 分子名称: | (2S)-HEX-5-ENE-1,2-DIOL, CALCIUM ION, SULFATE ION, ... | 著者 | Mattos, C, Bellamacina, C.R, Peisach, E, Pereira, A, Vitkup, D, Petsko, G.A, Ringe, D. | 登録日 | 2006-01-13 | 公開日 | 2006-04-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Multiple solvent crystal structures: Probing binding sites, plasticity and hydration J.Mol.Biol., 357, 2006
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2FUV
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![BU of 2fuv by Molmil](/molmil-images/mine/2fuv) | Phosphoglucomutase from Salmonella typhimurium. | 分子名称: | MAGNESIUM ION, phosphoglucomutase | 著者 | Osipiuk, J, Wu, R, Holzle, D, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2006-01-27 | 公開日 | 2006-03-07 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | X-ray crystal structure of phosphoglucomutase from Salmonella typhimurium. To be Published
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2FZB
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![BU of 2fzb by Molmil](/molmil-images/mine/2fzb) | Human Aldose Reductase complexed with four tolrestat molecules at 1.5 A resolution. | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TOLRESTAT, aldose reductase | 著者 | Steuber, H, Zentgraf, M, Gerlach, C, Sotriffer, C.A, Heine, A, Klebe, G. | 登録日 | 2006-02-09 | 公開日 | 2006-10-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Expect the Unexpected or Caveat for Drug Designers: Multiple Structure Determinations Using Aldose Reductase Crystals Treated under Varying Soaking and Co-crystallisation Conditions. J.Mol.Biol., 363, 2006
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2FZ8
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![BU of 2fz8 by Molmil](/molmil-images/mine/2fz8) | Human Aldose reductase complexed with inhibitor zopolrestat at 1.48 A(1 day soaking). | 分子名称: | 3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, aldose reductase | 著者 | Steuber, H, Zentgraf, M, Gerlach, C, Sotriffer, C.A, Heine, A, Klebe, G. | 登録日 | 2006-02-09 | 公開日 | 2006-10-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Expect the Unexpected or Caveat for Drug Designers: Multiple Structure Determinations Using Aldose Reductase Crystals Treated under Varying Soaking and Co-crystallisation Conditions. J.Mol.Biol., 363, 2006
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2FZS
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2FZJ
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![BU of 2fzj by Molmil](/molmil-images/mine/2fzj) | New Insights into DHFR Interactions: Analysis of Pneumocystis carinii and Mouse DHFR Complexes with NADPH and Two Highly Potent Trimethoprim Derivatives | 分子名称: | 2,4-DIAMINO-5-[3',4'-DIMETHOXY-5'-(5-CARBOXYL-1-PENTYNYL)]BENZYL PYRIMIDINE, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Cody, V, Pace, J, Chisum, K, Rosowsky, A. | 登録日 | 2006-02-09 | 公開日 | 2006-12-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | New insights into DHFR interactions: analysis of Pneumocystis carinii and mouse DHFR complexes with NADPH and two highly potent 5-(omega-carboxy(alkyloxy) trimethoprim derivatives reveals conformational correlations with activity and novel parallel ring stacking interactions. Proteins, 65, 2006
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2G7H
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2FN4
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![BU of 2fn4 by Molmil](/molmil-images/mine/2fn4) | The crystal structure of human Ras-related protein, RRAS, in the GDP-bound state | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein R-Ras | 著者 | Turnbull, A.P, Elkins, J.M, Gileadi, C, Burgess, N, Salah, E, Papagrigoriou, E, Debreczeni, J, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D, Structural Genomics Consortium (SGC) | 登録日 | 2006-01-10 | 公開日 | 2006-01-31 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | The crystal structure of human Ras-related protein, RRAS, in the GDP-bound state To be Published
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8F8E
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![BU of 8f8e by Molmil](/molmil-images/mine/8f8e) | Crystal structure of the WDR domain of human DCAF1 in complex with OICR-8268 compound | 分子名称: | (3P)-N-[(1S)-3-amino-1-(3-chloro-4-fluorophenyl)-3-oxopropyl]-3-(4-chloro-2-fluorophenyl)-1H-pyrazole-4-carboxamide, CITRIC ACID, DDB1- and CUL4-associated factor 1 | 著者 | Kimani, S, Li, A, Dong, A, Li, Y, Hutchinson, A, Seitova, A, Wilson, B, Al-Awar, R, Vedadi, M, Brown, P, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) | 登録日 | 2022-11-21 | 公開日 | 2023-03-01 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal structure of the WDR domain of human DCAF1 in complex with OICR-8268 compound To be published
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2FQ2
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![BU of 2fq2 by Molmil](/molmil-images/mine/2fq2) | Solution structure of minor conformation of holo-acyl carrier protein from malaria parasite plasmodium falciparum | 分子名称: | 4'-PHOSPHOPANTETHEINE, acyl carrier protein | 著者 | Sharma, A.K, Sharma, S.K, Surolia, A, Surolia, N, Sarma, S.P. | 登録日 | 2006-01-17 | 公開日 | 2006-08-08 | 最終更新日 | 2022-03-09 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structures of conformationally equilibrium forms of holo-acyl carrier protein (PfACP) from Plasmodium falciparum provides insight into the mechanism of activation of ACPs Biochemistry, 45, 2006
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2FS4
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![BU of 2fs4 by Molmil](/molmil-images/mine/2fs4) | Ketopiperazine-Based Renin Inhibitors: Optimization of the C ring | 分子名称: | (6R)-6-({[1-(3-HYDROXYPROPYL)-1,7-DIHYDROQUINOLIN-7-YL]OXY}METHYL)-1-(4-{3-[(2-METHOXYBENZYL)OXY]PROPOXY}PHENYL)PIPERAZIN-2-ONE, Renin | 著者 | Holsworth, D.D, Cai, C, Cheng, X.-M, Cody, W.L, Downing, D.M, Erasga, N, Lee, C, Powell, N.A, Edmunds, J.J, Stier, M, Jalaie, M, Zhang, E, McConnell, P, Ryan, M.J, Bryant, J, Li, T, Kasani, A, Hall, E, Subedi, R, Rahim, M, Maiti, S. | 登録日 | 2006-01-20 | 公開日 | 2006-06-13 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Ketopiperazine-Based Renin Inhibitors: Optimization of the "C" Ring BIOORG.MED.CHEM.LETT., 16, 2006
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2FVO
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![BU of 2fvo by Molmil](/molmil-images/mine/2fvo) | Docking of the modified RF1 X-ray structure into the Low Resolution Cryo-EM map of E.coli 70S Ribosome bound with RF1 | 分子名称: | Peptide chain release factor 1 | 著者 | Rawat, U, Gao, H, Zavialov, A, Gursky, R, Ehrenberg, M, Frank, J. | 登録日 | 2006-01-31 | 公開日 | 2006-04-04 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (12.8 Å) | 主引用文献 | Interactions of the Release Factor RF1 with the Ribosome as Revealed by Cryo-EM. J.Mol.Biol., 357, 2006
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2FW2
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![BU of 2fw2 by Molmil](/molmil-images/mine/2fw2) | Catalytic domain of CDY | 分子名称: | Testis-specific chromodomain protein Y 2 | 著者 | Min, J.R, Antoshenko, T, Wu, H, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) | 登録日 | 2006-01-31 | 公開日 | 2006-02-14 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Crystal Structure of catalytic domain of Human Testis-specific chromodomain protein Y. To be Published
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2G03
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![BU of 2g03 by Molmil](/molmil-images/mine/2g03) | Structure of a putative cell filamentation protein from Neisseria meningitidis. | 分子名称: | ACETIC ACID, ISOPROPYL ALCOHOL, hypothetical protein NMA0004 | 著者 | Cuff, M.E, Bigelow, L, Bargassa, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2006-02-10 | 公開日 | 2006-03-21 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of a putative cell filamentation protein from Neisseria meningitidis. To be Published
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2G5I
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![BU of 2g5i by Molmil](/molmil-images/mine/2g5i) | Structure of tRNA-Dependent Amidotransferase GatCAB complexed with ADP-AlF4 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, ... | 著者 | Nakamura, A, Yao, M, Tanaka, I. | 登録日 | 2006-02-23 | 公開日 | 2006-07-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Ammonia channel couples glutaminase with transamidase reactions in GatCAB Science, 312, 2006
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2GAU
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![BU of 2gau by Molmil](/molmil-images/mine/2gau) | Crystal structure of transcriptional regulator, Crp/Fnr family from Porphyromonas gingivalis (APC80792), Structural genomics, MCSG | 分子名称: | transcriptional regulator, Crp/Fnr family | 著者 | Rotella, F.J, Zhang, R.G, Mulligan, R, Moy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2006-03-09 | 公開日 | 2006-04-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The 1.9-A crystal structure of transcriptional regulator, Crp/Fnr family from Porphyromonas gingivalis To be Published
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