6C5X
 
 | | Crystal Structure of SOCS1 in complex with ElonginB and ElonginC | | 分子名称: | Elongin-B, Elongin-C, GP130 peptide fragment, ... | | 著者 | Kershaw, N.J, Laktyushin, A, Babon, J.J. | | 登録日 | 2018-01-17 | | 公開日 | 2018-05-02 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3.105 Å) | | 主引用文献 | The molecular basis of JAK/STAT inhibition by SOCS1.
Nat Commun, 9, 2018
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6HBV
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5MFY
 | | RBM5 OCRE domain | | 分子名称: | RNA-binding protein 5 | | 著者 | Warner, L.R, Mourao, A, Soni, K, Sattler, M. | | 登録日 | 2016-11-19 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for the recognition of spliceosomal SmN/B/B' proteins by the RBM5 OCRE domain in splicing regulation.
Elife, 5, 2016
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4YEO
 | | Triclinic HEWL co-crystallised with cisplatin, studied at a data collection temperature of 150K - new refinement | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Cisplatin, ... | | 著者 | Shabalin, I.G, Dauter, Z, Jaskolski, M, Minor, W, Wlodawer, A. | | 登録日 | 2015-02-24 | | 公開日 | 2015-03-04 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (0.98 Å) | | 主引用文献 | Crystallography and chemistry should always go together: a cautionary tale of protein complexes with cisplatin and carboplatin.
Acta Crystallogr.,Sect.D, 71, 2015
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6C7Y
 | | Crystal structure of inhibitory protein SOCS1 in complex with JAK1 kinase domain | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Liau, N.P.D, Laktyushin, A, Lucet, I.S, Murphy, J.M, Yao, S, Callaghan, K, Nicola, N.A, Kershaw, N.J, Babon, J.J. | | 登録日 | 2018-01-23 | | 公開日 | 2018-05-02 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.499 Å) | | 主引用文献 | The molecular basis of JAK/STAT inhibition by SOCS1.
Nat Commun, 9, 2018
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4YQY
 | | Crystal Structure of a putative Dehydrogenase from Sulfitobacter sp. (COG1028) (TARGET EFI-513936) in its APO form | | 分子名称: | MAGNESIUM ION, Putative Dehydrogenase | | 著者 | Yadava, U, Vetting, M.W, Al Obaidi, N.F, Toro, R, Morisco, L.L, Benach, J, Koss, J, Wasserman, S.R, Attonito, J.D, Scott Glenn, A, Chamala, S, Chowdhury, S, Lafleur, J, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | | 登録日 | 2015-03-13 | | 公開日 | 2015-03-25 | | 実験手法 | X-RAY DIFFRACTION (1.381 Å) | | 主引用文献 | Crystal Structure of a putative Dehydrogenase from Sulfitobacter sp. (COG1028, TARGET EFI-513936) in its APO form
To be published
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6HKN
 | | Crystal structure of Compound 35 with ERK5 | | 分子名称: | Mitogen-activated protein kinase 7, [2-azanyl-4-(trifluoromethyloxy)phenyl]-[4-(7-methoxyquinazolin-4-yl)piperidin-1-yl]methanone | | 著者 | Nguyen, D, Lemos, C, Wortmann, L, Eis, K, Holton, S.J, Boemer, U, Lechner, C, Prechtl, S, Suelze, D, Siegel, F, Prinz, F, Lesche, R, Nicke, B, Mumberg, D, Bauser, M, Haegebarth, A. | | 登録日 | 2018-09-07 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Discovery and Characterization of the Potent and Highly Selective (Piperidin-4-yl)pyrido[3,2- d]pyrimidine Based in Vitro Probe BAY-885 for the Kinase ERK5.
J. Med. Chem., 62, 2019
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6HKS
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6BY4
 | | Single-State 14-mer UUCG Tetraloop calculated from Exact NOEs | | 分子名称: | RNA (5'-R(P*GP*GP*CP*AP*CP*UP*UP*CP*GP*GP*UP*GP*CP*C)-3') | | 著者 | Nichols, P.J, Henen, M.A, Born, A, Strotz, D, Guntert, P, Vogeli, B. | | 登録日 | 2017-12-19 | | 公開日 | 2018-06-13 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | High-resolution small RNA structures from exact nuclear Overhauser enhancement measurements without additional restraints.
Commun Biol, 1, 2018
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5MWW
 | | Sigma1.1 domain of sigmaA from Bacillus subtilis | | 分子名称: | RNA polymerase sigma factor SigA | | 著者 | Zachrdla, M, Padrta, P, Rabatinova, A, Sanderova, H, Barvik, I, Krasny, L, Zidek, L. | | 登録日 | 2017-01-20 | | 公開日 | 2017-06-14 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of domain 1.1 of the sigma (A) factor from Bacillus subtilis is preformed for binding to the RNA polymerase core.
J. Biol. Chem., 292, 2017
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6HN0
 | | Complex of Ovine Serum Albumin with diclofenac | | 分子名称: | (2S)-2-hydroxybutanedioic acid, 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, ACETATE ION, ... | | 著者 | Talaj, J.A, Bujacz, A, Bujacz, G. | | 登録日 | 2018-09-13 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Structural Investigation of Diclofenac Binding to Ovine, Caprine, and Leporine Serum Albumins.
Int J Mol Sci, 24, 2023
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3OY1
 | | Highly Selective c-Jun N-Terminal Kinase (JNK) 2 and 3 Inhibitors with In Vitro CNS-like Pharmacokinetic Properties | | 分子名称: | 5-[2-(cyclohexylamino)pyridin-4-yl]-4-naphthalen-2-yl-2-(tetrahydro-2H-pyran-4-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one, Mitogen-activated protein kinase 10 | | 著者 | Probst, G.D, Bowers, S, Sealy, J.M, Truong, A, Neitz, J, Hom, R.K, Galemmo Jr, R.A, Konradi, A.W, Sham, H.L, Quincy, D, Pan, H, Yao, N. | | 登録日 | 2010-09-22 | | 公開日 | 2011-08-17 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Highly selective c-Jun N-terminal kinase (JNK) 2 and 3 inhibitors with in vitro CNS-like pharmacokinetic properties prevent neurodegeneration.
Bioorg.Med.Chem.Lett., 21, 2011
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6BY5
 | | Two-State 14-mer UUCG Tetraloop calculated from Exact NOEs (State one: Conformers 1-5, State Two: Conformers 6-10) | | 分子名称: | RNA (5'-R(P*GP*GP*CP*AP*CP*UP*UP*CP*GP*GP*UP*GP*CP*C)-3') | | 著者 | Nichols, P.J, Henen, M.A, Born, A, Strotz, D, Guntert, P, Vogeli, B. | | 登録日 | 2017-12-19 | | 公開日 | 2018-06-13 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | High-resolution small RNA structures from exact nuclear Overhauser enhancement measurements without additional restraints.
Commun Biol, 1, 2018
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4YTR
 | | Crystal structure of D-tagatose 3-epimerase C66S from Pseudomonas cichorii in complex with 1-deoxy L-tagatose | | 分子名称: | 1-deoxy-L-tagatose, 1-deoxy-beta-L-tagatopyranose, D-tagatose 3-epimerase, ... | | 著者 | Yoshida, H, Yoshihara, A, Ishii, T, Izumori, K, Kamitori, S. | | 登録日 | 2015-03-18 | | 公開日 | 2016-03-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | X-ray structures of the Pseudomonas cichorii D-tagatose 3-epimerase mutant form C66S recognizing deoxy sugars as substrates
Appl. Microbiol. Biotechnol., 100, 2016
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4YUH
 | | Multiconformer synchrotron model of CypA at 150 K | | 分子名称: | Peptidyl-prolyl cis-trans isomerase A | | 著者 | Keedy, D.A, Kenner, L.R, Warkentin, M, Woldeyes, R.A, Thompson, M.C, Brewster, A.S, Van Benschoten, A.H, Baxter, E.L, Hopkins, J.B, Uervirojnangkoorn, M, McPhillips, S.E, Song, J, Mori, R.A, Holton, J.M, Weis, W.I, Brunger, A.T, Soltis, M, Lemke, H, Gonzalez, A, Sauter, N.K, Cohen, A.E, van den Bedem, H, Thorne, R.E, Fraser, J.S. | | 登録日 | 2015-03-18 | | 公開日 | 2015-10-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | | 主引用文献 | Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography.
Elife, 4, 2015
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6HOZ
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4Y3I
 | | PAS-GAF fragment from Deinococcus radiodurans BphP assembled with BV - Y307S, low dose | | 分子名称: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, Bacteriophytochrome | | 著者 | Li, F, Burgie, E.S, Yu, T, Heroux, A, Schatz, G.C, Vierstra, R.D, Orville, A.M. | | 登録日 | 2015-02-10 | | 公開日 | 2015-05-20 | | 最終更新日 | 2019-11-27 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | X-ray radiation induces deprotonation of the bilin chromophore in crystalline D. radiodurans phytochrome.
J.Am.Chem.Soc., 137, 2015
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6HS5
 | | N-terminal domain including the conserved ImpA_N region of the TssA component of the type VI secretion system from Burkholderia cenocepacia | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, TssA | | 著者 | Dix, S.R, Owen, H.J, Sun, R, Ahmad, A, Shastri, S, Spiewak, H.L, Mosby, D.J, Harris, M.J, Batters, S.L, Brooker, T.A, Tzokov, S.B, Sedelnikova, S.E, Baker, P.J, Bullough, P.A, Rice, D.W, Thomas, M.S. | | 登録日 | 2018-09-28 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural insights into the function of type VI secretion system TssA subunits.
Nat Commun, 9, 2018
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6HSD
 | | Crystal structure of the oxidized form of the transcription regulator RsrR | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Volbeda, A, Fontecilla-Camps, J.C. | | 登録日 | 2018-09-30 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal Structure of the Transcription Regulator RsrR Reveals a [2Fe-2S] Cluster Coordinated by Cys, Glu, and His Residues.
J. Am. Chem. Soc., 141, 2019
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6H8N
 | | Structure of peptidoglycan deacetylase PdaC from Bacillus subtilis - mutant D285S | | 分子名称: | GLYCEROL, PHOSPHATE ION, Peptidoglycan-N-acetylmuramic acid deacetylase PdaC, ... | | 著者 | Sainz-Polo, M.A, Grifoll-Romero, L, Albesa-Jove, D, Planas, A, Guerin, M.E. | | 登録日 | 2018-08-02 | | 公開日 | 2019-11-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | | 主引用文献 | Structure-function relationships underlying the dualN-acetylmuramic andN-acetylglucosamine specificities of the bacterial peptidoglycan deacetylase PdaC.
J.Biol.Chem., 294, 2019
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2VTB
 | | Structure of cryptochrome 3 - DNA complex | | 分子名称: | 5'-D(*DT*DT*DT*DT*DTP)-3', 5,10-METHENYL-6,7,8-TRIHYDROFOLIC ACID, ACETATE ION, ... | | 著者 | Pokorny, R, Klar, T, Hennecke, U, Carell, T, Batschauer, A, Essen, L.-O. | | 登録日 | 2008-05-13 | | 公開日 | 2009-06-02 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Recognition and Repair of Uv Lesions in Loop Structures of Duplex DNA by Dash-Type Cryptochrome.
Proc.Natl.Acad.Sci.USA, 105, 2008
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6HTL
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4Y8F
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4Y96
 | | Crystal structure of Triosephosphate Isomerase from Gemmata obscuriglobus | | 分子名称: | CALCIUM ION, PHOSPHATE ION, SODIUM ION, ... | | 著者 | Romero-Romero, S, Rodriguez-Romero, A, Fernandez-Velasco, D.A. | | 登録日 | 2015-02-17 | | 公開日 | 2015-07-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.581 Å) | | 主引用文献 | Reversibility and two state behaviour in the thermal unfolding of oligomeric TIM barrel proteins.
Phys Chem Chem Phys, 17, 2015
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4YPV
 | | High-resolution structure of a metagenome-derived esterase Est8 | | 分子名称: | Est8 | | 著者 | Pereira, M.R, Maester, C.T, Macedo Lemos, E, Hyvonen, M, Balan, A. | | 登録日 | 2015-03-13 | | 公開日 | 2016-05-18 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | From a metagenomic source to a high-resolution structure of a novel alkaline esterase.
Appl. Microbiol. Biotechnol., 2017
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