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7EWZ
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BU of 7ewz by Molmil
Crystal structure of Ebinur Lake virus cap snatching endonuclease (D92A mutant)
分子名称: CHLORIDE ION, MANGANESE (II) ION, Replicase
著者Kuang, W, Hu, Z, Gong, P.
登録日2021-05-26
公開日2022-01-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Insights into Two-Metal-Ion Catalytic Mechanism of Cap-Snatching Endonuclease of Ebinur Lake Virus in Bunyavirales.
J.Virol., 96, 2022
7EX6
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BU of 7ex6 by Molmil
Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 11
分子名称: MANGANESE (II) ION, Replicase, methyl (Z)-4-(4-(4-chlorobenzyl)-1-(2-methylbenzyl)piperidin-4-yl)-2-hydroxy-4-oxobut-2-enoate
著者Kuang, W, Hu, Z, Gong, P.
登録日2021-05-26
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
7EX0
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BU of 7ex0 by Molmil
Crystal structure of Ebinur Lake virus cap snatching endonuclease (K108A mutant)
分子名称: MANGANESE (II) ION, Replicase
著者Kuang, W, Hu, Z, Gong, P.
登録日2021-05-26
公開日2022-01-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Insights into Two-Metal-Ion Catalytic Mechanism of Cap-Snatching Endonuclease of Ebinur Lake Virus in Bunyavirales.
J.Virol., 96, 2022
7EX8
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BU of 7ex8 by Molmil
Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 27
分子名称: CHLORIDE ION, MANGANESE (II) ION, Replicase, ...
著者Kuang, W, Hu, Z, Gong, P.
登録日2021-05-26
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
7EX9
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BU of 7ex9 by Molmil
Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 28
分子名称: CHLORIDE ION, MANGANESE (II) ION, Replicase, ...
著者Kuang, W, Hu, Z, Gong, P.
登録日2021-05-26
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
7EX2
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BU of 7ex2 by Molmil
Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with L-742,001 (methyl ester form)
分子名称: MANGANESE (II) ION, Replicase, methyl (Z)-4-[4-[(4-chlorophenyl)methyl]-1-(phenylmethyl)piperidin-4-yl]-2-oxidanyl-4-oxidanylidene-but-2-enoate
著者Kuang, W, Hu, Z, Gong, P.
登録日2021-05-26
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
7EX4
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BU of 7ex4 by Molmil
Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 5
分子名称: CHLORIDE ION, MANGANESE (II) ION, Replicase, ...
著者Kuang, W, Hu, Z, Gong, P.
登録日2021-05-26
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
7EV3
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BU of 7ev3 by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Y-10 and ATP
分子名称: (5S)-5-[(1R)-1-(4-fluoranyl-1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4-one, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Xu, M, Chen, S.
登録日2021-05-20
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
7EX7
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BU of 7ex7 by Molmil
Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 16
分子名称: CHLORIDE ION, MANGANESE (II) ION, Replicase, ...
著者Kuang, W, Hu, Z, Gong, P.
登録日2021-05-26
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
7EX3
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BU of 7ex3 by Molmil
Crystal structure of Ebinur Lake virus cap snatching endonuclease in complex with inhibitor 3
分子名称: CHLORIDE ION, MANGANESE (II) ION, Replicase, ...
著者Kuang, W, Hu, Z, Gong, P.
登録日2021-05-26
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural and Biochemical Basis for Development of Diketo Acid Inhibitors Targeting the Cap-Snatching Endonuclease of the Ebinur Lake Virus (Order: Bunyavirales ).
J.Virol., 96, 2022
7EV2
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BU of 7ev2 by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Y-11 and ATP
分子名称: (5S)-5-[(1R)-1-(4-chloranyl-1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4-one, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Xu, M, Chen, S.
登録日2021-05-20
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
7F45
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BU of 7f45 by Molmil
Structure of an Anti-CRISPR protein
分子名称: AcrIF5
著者Feng, Y.
登録日2021-06-17
公開日2022-03-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.52 Å)
主引用文献AcrIF5 specifically targets DNA-bound CRISPR-Cas surveillance complex for inhibition.
Nat.Chem.Biol., 18, 2022
7EQG
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BU of 7eqg by Molmil
Structure of Csy-AcrIF5
分子名称: AcrIF5, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR-associated protein Csy3, ...
著者Zhang, L, Feng, Y.
登録日2021-05-01
公開日2022-03-09
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献AcrIF5 specifically targets DNA-bound CRISPR-Cas surveillance complex for inhibition.
Nat.Chem.Biol., 18, 2022
5YAX
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BU of 5yax by Molmil
Crystal structure of a human neutralizing antibody bound to a HBV preS1 peptide
分子名称: Large envelope protein, SODIUM ION, scFv1 antibody
著者Liu, X, Zheng, S, Ye, K, Sui, J.
登録日2017-09-02
公開日2017-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A potent human neutralizing antibody Fc-dependently reduces established HBV infections
Elife, 6, 2017
5C0M
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BU of 5c0m by Molmil
Crystal structure of SGF29 tandem tudor domain in complex with a Carba containing peptide
分子名称: Carba-containing peptide, GLYCEROL, SAGA-associated factor 29 homolog, ...
著者Dong, A, Xu, C, Tempel, W, Cerovina, T, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2015-06-12
公開日2015-07-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Chemical basis for the recognition of trimethyllysine by epigenetic reader proteins.
Nat Commun, 6, 2015
7LUA
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BU of 7lua by Molmil
Cryo-EM structure of DH898.1 Fab-dimer bound near the CD4 binding site of HIV-1 Env CH848 SOSIP trimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848 SOSIP gp120, ...
著者Manne, K, Edwards, R.J, Acharya, P.
登録日2021-02-21
公開日2021-03-17
最終更新日2021-06-09
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Cell, 184, 2021
7LU9
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BU of 7lu9 by Molmil
Cryo-EM structure of DH851.3 bound to HIV-1 CH505 Env
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Manne, K, Edwards, R.J, Acharya, P.
登録日2021-02-21
公開日2021-03-24
最終更新日2021-06-09
実験手法ELECTRON MICROSCOPY (5.6 Å)
主引用文献Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Cell, 184, 2021
4ZOL
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BU of 4zol by Molmil
Crystal Structure of Tubulin-Stathmin-TTL-Tubulysin M Complex
分子名称: (2R,4R)-4-{[(2-{(1R,3R)-1-(acetyloxy)-4-methyl-3-[methyl(N-{[(2S)-1-methylpiperidin-2-yl]carbonyl}-D-isoleucyl)amino]pentyl}-1,3-thiazol-4-yl)carbonyl]amino}-2-methyl-5-phenylpentanoic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
著者Wang, Y, Zhang, R.
登録日2015-05-06
公開日2016-07-27
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules
Mol.Pharmacol., 89, 2016
1XC3
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BU of 1xc3 by Molmil
Structure of a Putative Fructokinase from Bacillus subtilis
分子名称: GLYCEROL, PLATINUM (II) ION, Putative fructokinase, ...
著者Cuff, M.E, Quartey, P, Lezondra, L, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2004-08-31
公開日2004-10-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural studies of ROK fructokinase YdhR from Bacillus subtilis: insights into substrate binding and fructose specificity.
J.Mol.Biol., 406, 2011
4ZKT
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BU of 4zkt by Molmil
Crystal structure of the progenitor M complex of Clostridium botulinum type E neurotoxin
分子名称: Bontoxilysin A, Botulinum neurotoxin type E, nontoxic-nonhemagglutinin component, ...
著者Eswaramoorthy, S, Swaminathan, S.
登録日2015-04-30
公開日2015-12-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Molecular Assembly of Clostridium botulinum progenitor M complex of type E.
Sci Rep, 5, 2015
4Z7P
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BU of 4z7p by Molmil
X-ray structure of racemic ShK Q16K toxin
分子名称: Potassium channel toxin kappa-stichotoxin-She1a, SULFATE ION
著者Sickmier, E.A.
登録日2015-04-07
公開日2015-09-09
最終更新日2015-09-23
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Pharmaceutical Optimization of Peptide Toxins for Ion Channel Targets: Potent, Selective, and Long-Lived Antagonists of Kv1.3.
J.Med.Chem., 58, 2015
7WW2
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BU of 7ww2 by Molmil
Structure of an Isocytosine specific deaminase Vcz
分子名称: 8-oxoguanine deaminase, ZINC ION
著者Li, X.J, Wu, B.X.
登録日2022-02-12
公開日2023-02-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural characterization of an isocytosine-specific deaminase VCZ reveals its application potential in the anti-cancer therapy.
Iscience, 26, 2023
4Y7N
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BU of 4y7n by Molmil
The Structure Insight into 5-Carboxycytosine Recognition by RNA Polymerase II during Transcription Elongation.
分子名称: DNA (29-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
著者Wang, L, Chong, J, Wang, D.
登録日2015-02-15
公開日2015-07-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex.
Nature, 523, 2015
4ZHQ
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BU of 4zhq by Molmil
Crystal structure of Tubulin-Stathmin-TTL-MMAE Complex
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ...
著者Wang, Y, Zhang, R.
登録日2015-04-26
公開日2016-07-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules
Mol.Pharmacol., 89, 2016
4ZI7
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BU of 4zi7 by Molmil
CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-HTI286 COMPLEX
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ...
著者Wang, Y, Zhang, R.
登録日2015-04-27
公開日2016-07-27
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules
Mol.Pharmacol., 89, 2016

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件を2024-08-07に公開中

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