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3D4L
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BU of 3d4l by Molmil
Human dipeptidyl peptidase IV/CD26 in complex with a novel inhibitor
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Scapin, G.
登録日2008-05-14
公開日2008-07-01
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of new binding elements in DPP-4 inhibition and their applications in novel DPP-4 inhibitor design.
Bioorg.Med.Chem.Lett., 18, 2008
6V63
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BU of 6v63 by Molmil
SETD3 WT in Complex with an Actin Peptide with His73 Replaced with Glutamine
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Actin, ...
著者Dai, S, Horton, J.R, Cheng, X.
登録日2019-12-04
公開日2020-01-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献An engineered variant of SETD3 methyltransferase alters target specificity from histidine to lysine methylation.
J.Biol.Chem., 295, 2020
7N5U
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BU of 7n5u by Molmil
ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing GGACCC (Oligo 21)
分子名称: DNA Strain II, DNA Strand I, ZINC ION, ...
著者Horton, J.R, Ren, R, Cheng, X.
登録日2021-06-06
公開日2022-06-08
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
J.Biol.Chem., 299, 2023
7N5W
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BU of 7n5w by Molmil
ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing GGACCC (Oligo 23)
分子名称: 1,2-ETHANEDIOL, DNA Strand I, DNA Strand II, ...
著者Horton, J.R, Ren, R, Cheng, X.
登録日2021-06-06
公開日2022-06-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
J.Biol.Chem., 299, 2023
7N5V
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BU of 7n5v by Molmil
ZBTB7A Zinc Finger Domain Bound to DNA Duplex Containing GGACCC (Oligo 20)
分子名称: DNA Strand I, DNA Strand II, ZINC ION, ...
著者Horton, J.R, Ren, R, Cheng, X.
登録日2021-06-06
公開日2022-06-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.08 Å)
主引用文献Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
J.Biol.Chem., 299, 2023
7B7V
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BU of 7b7v by Molmil
Structure of NUDT15 in complex with Acyclovir monophosphate
分子名称: 2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl dihydrogen phosphate, CHLORIDE ION, MAGNESIUM ION, ...
著者Rehling, D, Stenmark, P.
登録日2020-12-11
公開日2021-05-19
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献NUDT15 polymorphism influences the metabolism and therapeutic effects of acyclovir and ganciclovir.
Nat Commun, 12, 2021
6UKH
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BU of 6ukh by Molmil
HhaI endonuclease in Complex with DNA in space group P41212 (pH 6.0)
分子名称: CALCIUM ION, DNA (5'-D(*CP*CP*AP*AP*GP*CP*GP*CP*AP*AP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*TP*TP*GP*CP*GP*CP*TP*TP*GP*G)-3'), ...
著者Horton, J.R, Cheng, X.
登録日2019-10-04
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Structure of HhaI endonuclease with cognate DNA at an atomic resolution of 1.0 angstrom.
Nucleic Acids Res., 48, 2020
4N90
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BU of 4n90 by Molmil
Crystal structure of ternary complex of TRAIL, DR5, and Fab fragment from a DR5 agonist antibody
分子名称: Fab heavy chain, Fab light chain, Tumor necrosis factor ligand superfamily member 10, ...
著者Huang, X.
登録日2013-10-18
公開日2014-09-03
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Apo2L/TRAIL and the Death Receptor 5 Agonist Antibody AMG 655 Cooperate to Promote Receptor Clustering and Antitumor Activity.
Cancer Cell, 26, 2014
7L4X
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BU of 7l4x by Molmil
YTH Domain of Human YTHDC1 with dsDNA Comprising Single N6mA joined by two six-bp DNA duplexes in P3221 Crystal
分子名称: 1,2-ETHANEDIOL, YTH domain-containing protein 1, ssDNA w/N6A
著者Horton, J.R, Cheng, X.
登録日2020-12-21
公開日2021-11-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Human MettL3-MettL14 RNA adenine methyltransferase complex is active on double-stranded DNA containing lesions.
Nucleic Acids Res., 49, 2021
7L4Y
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BU of 7l4y by Molmil
YTH Domain of Human YTHDC1 with dsDNA Comprising Single N6mA joined by Two Six-bp DNA Duplexes in P212121 Crystal
分子名称: 1,2-ETHANEDIOL, YTH domain-containing protein 1, ssDNA 13mer
著者Horton, J.R, Cheng, X.
登録日2020-12-21
公開日2021-11-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Human MettL3-MettL14 RNA adenine methyltransferase complex is active on double-stranded DNA containing lesions.
Nucleic Acids Res., 49, 2021
7L4V
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BU of 7l4v by Molmil
C-terminal bZIP domain of human C/EBPbeta Bound to DNA with Consensus Recognition with GT Mismatch
分子名称: 1,2-ETHANEDIOL, CCAAT/enhancer-binding protein beta, DNA Strand 1, ...
著者Horton, J.R, Cheng, X.
登録日2020-12-21
公開日2021-11-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Preferential CEBP binding to T:G mismatches and increased C-to-T human somatic mutations.
Nucleic Acids Res., 49, 2021
6V62
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BU of 6v62 by Molmil
SETD3 double mutant (N255F/W273A) in Complex with an Actin Peptide with His73 Replaced with Lysine
分子名称: 1,2-ETHANEDIOL, Actin, cytoplasmic 1, ...
著者Dai, S, Horton, J.R, Cheng, X.
登録日2019-12-04
公開日2020-01-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献An engineered variant of SETD3 methyltransferase alters target specificity from histidine to lysine methylation.
J.Biol.Chem., 295, 2020
5D6P
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BU of 5d6p by Molmil
Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a ligand
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1-ethyl-3-[4-(hydroxymethyl)-5-(1H-pyrrol-2-yl)-1,3-thiazol-2-yl]urea, DNA gyrase subunit B, ...
著者Zhang, J, Yang, Q, Cross, J.B, Romero, J.A.C, Ryan, M.D, Lippa, B, Dolle, R.E, Andersen, O.A, Barker, J, Cheng, R.K, Kahmann, J, Felicetti, B, Wood, M, Scheich, C.
登録日2015-08-12
公開日2015-11-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors.
J.Med.Chem., 58, 2015
6JIQ
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BU of 6jiq by Molmil
Crystal structure of Streptococcus pneumoniae SP_0782 (residues 7-79) in complex with single-stranded DNA dT6
分子名称: DNA (5'-D(*TP*TP*TP*TP*T)-3'), SP_0782
著者Fang, X, Lu, G, Li, S, Zhu, J, Yang, Y, Gong, P.
登録日2019-02-22
公開日2019-11-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Structural insight into the length-dependent binding of ssDNA by SP_0782 from Streptococcus pneumoniae, reveals a divergence in the DNA-binding interface of PC4-like proteins.
Nucleic Acids Res., 48, 2020
6JIP
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BU of 6jip by Molmil
Crystal structure of Streptococcus pneumoniae SP_0782 (residues 7-79) in complex with single-stranded DNA dT6
分子名称: DNA (5'-D(*TP*TP*TP*TP*T)-3'), PENTAETHYLENE GLYCOL, SP_0782
著者Fang, X, Lu, G, Li, S, Zhu, J, Yang, Y, Gong, P.
登録日2019-02-22
公開日2019-11-27
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.659 Å)
主引用文献Structural insight into the length-dependent binding of ssDNA by SP_0782 from Streptococcus pneumoniae, reveals a divergence in the DNA-binding interface of PC4-like proteins.
Nucleic Acids Res., 48, 2020
7VY0
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BU of 7vy0 by Molmil
Coxsackievirus B3 full particle at pH7.4 (VP3-234N)
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Wang, Q.L, Liu, C.C.
登録日2021-11-13
公開日2022-01-19
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7W14
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BU of 7w14 by Molmil
Coxsackievirus B3 at pH7.4 (VP3-234E) incubation with coxsackievirus and adenovirus receptor for 20min
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Wang, Q.L, Liu, C.C.
登録日2021-11-19
公開日2022-01-19
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VYL
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BU of 7vyl by Molmil
Coxsackievirus B3 at pH5.5 (VP3-234Q) incubation with coxsackievirus and adenovirus receptor for 20min
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Wang, Q.L, Liu, C.C.
登録日2021-11-14
公開日2022-01-19
最終更新日2022-08-10
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VY6
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BU of 7vy6 by Molmil
Coxsackievirus B3(VP3-234N) incubate with CD55 at pH7.4
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Wang, Q.L, Liu, C.C.
登録日2021-11-13
公開日2022-01-19
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VY5
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BU of 7vy5 by Molmil
Coxsackievirus B3 (VP3-234Q) incubation with CD55 at pH7.4
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Wang, Q.L, Liu, C.C.
登録日2021-11-13
公開日2022-01-19
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VXZ
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BU of 7vxz by Molmil
Coxsackievirus B3 at pH7.4 (VP3-234Q) incubation with coxsackievirus and adenovirus receptor for 20min
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Wang, Q.L, Liu, C.C.
登録日2021-11-13
公開日2022-01-19
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.19 Å)
主引用文献Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VYM
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BU of 7vym by Molmil
Coxsackievirus B3 at pH7.4 (VP3-234E) incubation with coxsackievirus and adenovirus receptor for 10min
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Wang, Q.L, Liu, C.C.
登録日2021-11-14
公開日2022-01-19
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7W17
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BU of 7w17 by Molmil
Coxsackievirus B3 full particle at pH7.4 (VP3-234E)
分子名称: PALMITIC ACID, VP1, VP2, ...
著者Wang, Q.L, Liu, C.C.
登録日2021-11-19
公開日2022-01-19
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VYK
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BU of 7vyk by Molmil
Coxsackievirus B3 at pH7.4 (VP3-234Q) incubation with coxsackievirus and adenovirus receptor for 10min
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Wang, Q.L, Liu, C.C.
登録日2021-11-14
公開日2022-01-19
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (2.79 Å)
主引用文献Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VXH
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BU of 7vxh by Molmil
Coxsackievirus B3 full particle at pH7.4 (VP3-234Q)
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Wang, Q.L, Liu, C.C.
登録日2021-11-12
公開日2022-01-19
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains.
Proc.Natl.Acad.Sci.USA, 119, 2022

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