8IY2
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![BU of 8iy2 by Molmil](/molmil-images/mine/8iy2) | Structure of Acb2 complexed with 3',3'-cGAMP and cAAA | 分子名称: | 1,2-ETHANEDIOL, GUANOSINE-3'-MONOPHOSPHATE, [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphate, ... | 著者 | Cao, X.L, Xiao, Y, Feng, Y. | 登録日 | 2023-04-03 | 公開日 | 2024-02-07 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | Phage anti-CBASS protein simultaneously sequesters cyclic trinucleotides and dinucleotides. Mol.Cell, 84, 2024
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8J8O
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![BU of 8j8o by Molmil](/molmil-images/mine/8j8o) | Structure of Acb2 complexed with 2',3'-cGAMP | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, cGAMP, ... | 著者 | Cao, X.L, Xiao, Y, Feng, Y. | 登録日 | 2023-05-02 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Phage anti-CBASS protein simultaneously sequesters cyclic trinucleotides and dinucleotides. Mol.Cell, 84, 2024
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5GZC
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![BU of 5gzc by Molmil](/molmil-images/mine/5gzc) | |
6JIV
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![BU of 6jiv by Molmil](/molmil-images/mine/6jiv) | SspE crystal structure | 分子名称: | SspE protein | 著者 | Bing, Y.Z, Yang, H.G. | 登録日 | 2019-02-23 | 公開日 | 2020-03-25 | 最終更新日 | 2020-07-08 | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | 主引用文献 | SspABCD-SspE is a phosphorothioation-sensing bacterial defence system with broad anti-phage activities. Nat Microbiol, 5, 2020
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5GZD
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![BU of 5gzd by Molmil](/molmil-images/mine/5gzd) | |
7KEK
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![BU of 7kek by Molmil](/molmil-images/mine/7kek) | |
5GZF
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8XAB
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![BU of 8xab by Molmil](/molmil-images/mine/8xab) | |
6QH9
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![BU of 6qh9 by Molmil](/molmil-images/mine/6qh9) | Crystal Structure of Human Kallikrein 6 in complex with GSK3239861A | 分子名称: | (3~{R})-~{N}-(4-carbamimidoylphenyl)-2-oxidanylidene-piperidine-3-carboxamide, (3~{S})-~{N}-(4-carbamimidoylphenyl)-2-oxidanylidene-piperidine-3-carboxamide, GLYCEROL, ... | 著者 | Thorpe, J.H. | 登録日 | 2019-01-16 | 公開日 | 2019-02-06 | 最終更新日 | 2019-02-27 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Kallikrein 5 inhibitors identified through structure based drug design in search for a treatment for Netherton Syndrome. Bioorg. Med. Chem. Lett., 29, 2019
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4ZMD
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8GQ6
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![BU of 8gq6 by Molmil](/molmil-images/mine/8gq6) | Cryo-EM Structure of the KBTBD2-CUL3-Rbx1 dimeric complex | 分子名称: | Cullin-3, E3 ubiquitin-protein ligase RBX1, Kelch repeat and BTB domain-containing protein 2, ... | 著者 | Sun, L, Chen, Z, Hu, Y, Mao, Q. | 登録日 | 2022-08-29 | 公開日 | 2023-09-06 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | 主引用文献 | Dynamic molecular architecture and substrate recruitment of cullin3-RING E3 ligase CRL3 KBTBD2. Nat.Struct.Mol.Biol., 31, 2024
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6QFG
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![BU of 6qfg by Molmil](/molmil-images/mine/6qfg) | Crystal Structure of Human Kallikrein 6 (I218Y) in complex with GSK144 | 分子名称: | 4-[(5-phenyl-1~{H}-imidazol-2-yl)methylamino]-2-(pyridin-3-ylmethoxy)benzenecarboximidamide, GLYCEROL, Kallikrein-6 | 著者 | Thorpe, J.H. | 登録日 | 2019-01-10 | 公開日 | 2019-05-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Evaluation of a crystallographic surrogate for kallikrein 5 in the discovery of novel inhibitors for Netherton syndrome. Acta Crystallogr.,Sect.F, 75, 2019
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6SKC
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4ZNC
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![BU of 4znc by Molmil](/molmil-images/mine/4znc) | |
6QFS
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![BU of 6qfs by Molmil](/molmil-images/mine/6qfs) | Chargeless variant of the Cellulose-binding domain from Cellulomonas fimi | 分子名称: | 1,2-ETHANEDIOL, 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, ... | 著者 | Young, D.R, Hoejgaard, C, Messens, J, Winther, J.R. | 登録日 | 2019-01-10 | 公開日 | 2019-12-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Charge Interactions in a Highly Charge-depleted Protein J.Am.Chem.Soc., 2021
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6QHB
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![BU of 6qhb by Molmil](/molmil-images/mine/6qhb) | Crystal Structure of Human Kallikrein 6 in complex with GSK578724A | 分子名称: | GLYCEROL, Kallikrein-6, ~{N}-(4-carbamimidoylphenyl)-3-methoxy-2-oxidanyl-benzamide | 著者 | Thorpe, J.H. | 登録日 | 2019-01-16 | 公開日 | 2019-02-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Kallikrein 5 inhibitors identified through structure based drug design in search for a treatment for Netherton Syndrome. Bioorg. Med. Chem. Lett., 29, 2019
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6JUF
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![BU of 6juf by Molmil](/molmil-images/mine/6juf) | SspB crystal structure | 分子名称: | SspB protein | 著者 | Liqiong, L, Yubing, Z. | 登録日 | 2019-04-13 | 公開日 | 2020-03-25 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.587 Å) | 主引用文献 | SspABCD-SspE is a phosphorothioation-sensing bacterial defence system with broad anti-phage activities. Nat Microbiol, 5, 2020
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8XV2
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![BU of 8xv2 by Molmil](/molmil-images/mine/8xv2) | Thiamine-bound human SLC19A3 | 分子名称: | 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, Soluble cytochrome b562,Thiamine transporter 2 | 著者 | Dang, Y, Wang, G.P, Zhang, Z. | 登録日 | 2024-01-14 | 公開日 | 2024-03-27 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Substrate and drug recognition mechanisms of SLC19A3. Cell Res., 34, 2024
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8XV5
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![BU of 8xv5 by Molmil](/molmil-images/mine/8xv5) | Pyridoxamine-bound human SLC19A3 | 分子名称: | 4-(AMINOMETHYL)-5-(HYDROXYMETHYL)-2-METHYLPYRIDIN-3-OL, Soluble cytochrome b562,Thiamine transporter 2 | 著者 | Dang, Y, Wang, G.P, Zhang, Z. | 登録日 | 2024-01-14 | 公開日 | 2024-03-27 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Substrate and drug recognition mechanisms of SLC19A3. Cell Res., 34, 2024
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8XNG
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8XV9
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![BU of 8xv9 by Molmil](/molmil-images/mine/8xv9) | Fedratinib-bound human SLC19A3 | 分子名称: | N-tert-butyl-3-{[5-methyl-2-({4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)pyrimidin-4-yl]amino}benzenesulfonamide, Soluble cytochrome b562,Thiamine transporter 2 | 著者 | Dang, Y, Wang, G.P, Zhang, Z. | 登録日 | 2024-01-14 | 公開日 | 2024-03-27 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Substrate and drug recognition mechanisms of SLC19A3. Cell Res., 34, 2024
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8K3S
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![BU of 8k3s by Molmil](/molmil-images/mine/8k3s) | Structure of PKD2-F604P complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ... | 著者 | Chen, M.Y, Su, Q, Wang, Z.F, Yu, Y. | 登録日 | 2023-07-16 | 公開日 | 2024-04-03 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Molecular and structural basis of the dual regulation of the polycystin-2 ion channel by small-molecule ligands. Proc.Natl.Acad.Sci.USA, 121, 2024
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8XVZ
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8XS4
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8XVX
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![BU of 8xvx by Molmil](/molmil-images/mine/8xvx) | |