4ZXC
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![BU of 4zxc by Molmil](/molmil-images/mine/4zxc) | Crystal Structure of hydroquinone 1,2-dioxygenase PnpCD in complex with Fe3+ | 分子名称: | FE (III) ION, Hydroquinone dioxygenase large subunit, Hydroquinone dioxygenase small subunit | 著者 | Liu, S, Su, T, Zhang, C, Gu, L. | 登録日 | 2015-05-20 | 公開日 | 2015-09-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Crystal Structure of PnpCD, a Two-subunit Hydroquinone 1,2-Dioxygenase, Reveals a Novel Structural Class of Fe2+-dependent Dioxygenases. J.Biol.Chem., 290, 2015
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4WXM
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![BU of 4wxm by Molmil](/molmil-images/mine/4wxm) | FleQ REC domain from Pseudomonas aeruginosa PAO1 | 分子名称: | Transcriptional regulator FleQ | 著者 | Su, T, Liu, S, Gu, L. | 登録日 | 2014-11-14 | 公開日 | 2015-09-23 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The REC domain mediated dimerization is critical for FleQ from Pseudomonas aeruginosa to function as a c-di-GMP receptor and flagella gene regulator J.Struct.Biol., 192, 2015
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4ES4
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![BU of 4es4 by Molmil](/molmil-images/mine/4es4) | Crystal structure of YdiV and FlhD complex | 分子名称: | Flagellar transcriptional regulator FlhD, Putative cyclic di-GMP regulator CdgR | 著者 | Li, B, Gu, L. | 登録日 | 2012-04-22 | 公開日 | 2012-10-10 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural insight of a concentration-dependent mechanism by which YdiV inhibits Escherichia coli flagellum biogenesis and motility Nucleic Acids Res., 40, 2012
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4LA3
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![BU of 4la3 by Molmil](/molmil-images/mine/4la3) | |
4LA2
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5CRL
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![BU of 5crl by Molmil](/molmil-images/mine/5crl) | |
6A5Q
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6AKR
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![BU of 6akr by Molmil](/molmil-images/mine/6akr) | Crystal structure of the PDE4D catalytic domain in complex with osthole | 分子名称: | 7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one, ZINC ION, cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 著者 | Wang, S, Huo, Y.W, Xie, Y. | 登録日 | 2018-09-03 | 公開日 | 2020-02-12 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.326 Å) | 主引用文献 | Airway relaxation mechanisms and structural basis of osthole for improving lung function in asthma. Sci.Signal., 13, 2020
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6A5S
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![BU of 6a5s by Molmil](/molmil-images/mine/6a5s) | Structure of 14-3-3 gamma in complex with TFEB 14-3-3 binding motif | 分子名称: | 14-3-3 protein gamma, MAGNESIUM ION, SODIUM ION, ... | 著者 | Xu, Y, Ren, J.Q, Feng, W. | 登録日 | 2018-06-25 | 公開日 | 2019-02-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | 主引用文献 | YWHA/14-3-3 proteins recognize phosphorylated TFEB by a noncanonical mode for controlling TFEB cytoplasmic localization. Autophagy, 15, 2019
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3Q7J
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![BU of 3q7j by Molmil](/molmil-images/mine/3q7j) | Engineered Thermoplasma Acidophilum F3 factor mimics human aminopeptidase N (APN) as a target for anticancer drug development | 分子名称: | L-phenylalanyl-N6-[(benzyloxy)carbonyl]-N1-hydroxy-L-lysinamide, Tricorn protease-interacting factor F3, ZINC ION | 著者 | Su, J, Wang, Q, Feng, J, Zhang, C, Zhu, D, We, T, Xu, W, Gu, L. | 登録日 | 2011-01-05 | 公開日 | 2011-07-27 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | Engineered Thermoplasma acidophilum factor F3 mimics human aminopeptidase N (APN) as a target for anticancer drug development Bioorg.Med.Chem., 19, 2011
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6JGF
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6JGV
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6JGX
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![BU of 6jgx by Molmil](/molmil-images/mine/6jgx) | Crystal structure of the transcriptional regulator CadR from P. putida in complex with Cadmium(II) and DNA | 分子名称: | CADMIUM ION, CadR, DNA (5'-D(*CP*AP*CP*CP*CP*TP*AP*TP*AP*GP*TP*GP*GP*CP*TP*AP*CP*AP*GP*GP*GP*T)-3'), ... | 著者 | Liu, X.C, Gan, J.H, Chen, H. | 登録日 | 2019-02-15 | 公開日 | 2019-09-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Selective cadmium regulation mediated by a cooperative binding mechanism in CadR. Proc.Natl.Acad.Sci.USA, 116, 2019
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6JGW
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6JNI
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6K0J
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![BU of 6k0j by Molmil](/molmil-images/mine/6k0j) | The co-crystal structure of DYRK2 with a small molecule inhibitor | 分子名称: | 3-(2,7-dimethoxyacridin-9-yl)sulfanylpropan-1-amine, Dual specificity tyrosine-phosphorylation-regulated kinase 2 | 著者 | Tiantian, W, Xiao, J. | 登録日 | 2019-05-06 | 公開日 | 2019-11-20 | 最終更新日 | 2019-12-18 | 実験手法 | X-RAY DIFFRACTION (2.352 Å) | 主引用文献 | Inhibition of dual-specificity tyrosine phosphorylation-regulated kinase 2 perturbs 26S proteasome-addicted neoplastic progression. Proc.Natl.Acad.Sci.USA, 116, 2019
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5XSN
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![BU of 5xsn by Molmil](/molmil-images/mine/5xsn) | The catalytic domain of GdpP with c-di-AMP | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, MANGANESE (II) ION, Phosphodiesterase acting on cyclic dinucleotides | 著者 | Wang, F, Gu, L. | 登録日 | 2017-06-14 | 公開日 | 2018-01-31 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | Structural and biochemical characterization of the catalytic domains of GdpP reveals a unified hydrolysis mechanism for the DHH/DHHA1 phosphodiesterase Biochem. J., 475, 2018
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5XSP
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![BU of 5xsp by Molmil](/molmil-images/mine/5xsp) | The catalytic domain of GdpP with 5'-pApA | 分子名称: | ADENOSINE MONOPHOSPHATE, MANGANESE (II) ION, Phosphodiesterase acting on cyclic dinucleotides | 著者 | Wang, F, Gu, L. | 登録日 | 2017-06-15 | 公開日 | 2018-01-31 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.146 Å) | 主引用文献 | Structural and biochemical characterization of the catalytic domains of GdpP reveals a unified hydrolysis mechanism for the DHH/DHHA1 phosphodiesterase Biochem. J., 475, 2018
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5XT3
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![BU of 5xt3 by Molmil](/molmil-images/mine/5xt3) | The catalytic domain of GdpP with c-di-GMP | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MANGANESE (II) ION, Phosphodiesterase acting on cyclic dinucleotides | 著者 | Wang, F, Gu, L. | 登録日 | 2017-06-16 | 公開日 | 2018-01-31 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.591 Å) | 主引用文献 | Structural and biochemical characterization of the catalytic domains of GdpP reveals a unified hydrolysis mechanism for the DHH/DHHA1 phosphodiesterase Biochem. J., 475, 2018
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5XSI
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![BU of 5xsi by Molmil](/molmil-images/mine/5xsi) | The catalytic domain of GdpP | 分子名称: | MANGANESE (II) ION, Phosphodiesterase acting on cyclic dinucleotides | 著者 | Wang, F, Gu, L. | 登録日 | 2017-06-14 | 公開日 | 2018-01-31 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural and biochemical characterization of the catalytic domains of GdpP reveals a unified hydrolysis mechanism for the DHH/DHHA1 phosphodiesterase Biochem. J., 475, 2018
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3O72
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![BU of 3o72 by Molmil](/molmil-images/mine/3o72) | Crystal structure of EfeB in complex with heme | 分子名称: | OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, Redox component of a tripartite ferrous iron transporter | 著者 | Liu, X, Du, Q, Wang, Z, Zhu, D, Huang, Y, Li, N, Xu, S, Gu, L. | 登録日 | 2010-07-30 | 公開日 | 2011-03-16 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structure and biochemical features of EfeB/YcdB from Escherichia coli O157: ASP235 plays divergent roles in different enzyme-catalyzed processes J.Biol.Chem., 286, 2011
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3TLQ
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![BU of 3tlq by Molmil](/molmil-images/mine/3tlq) | Crystal structure of EAL-like domain protein YdiV | 分子名称: | GLYCEROL, PHOSPHATE ION, Regulatory protein YdiV | 著者 | Li, B, Li, N, Wang, F, Guo, L, Liu, C, Zhu, D, Xu, S, Gu, L. | 登録日 | 2011-08-30 | 公開日 | 2012-09-12 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Structural insight of a concentration-dependent mechanism by which YdiV inhibits Escherichia coli flagellum biogenesis and motility Nucleic Acids Res., 40, 2012
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7DNR
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6DUP
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![BU of 6dup by Molmil](/molmil-images/mine/6dup) | CRYSTAL STRUCTURE OF PXR IN COMPLEX WITH COMPOUND 7 | 分子名称: | (2S)-2-({[3'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]oxy}methyl)-2,3-dihydro-7H-[1,3]oxazolo[3,2-a]pyrimidin-7-one, Nuclear receptor subfamily 1 group I member 2 | 著者 | Chen, X, Zhang, Y, Mclean, L.R. | 登録日 | 2018-06-21 | 公開日 | 2018-08-29 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Amelioration of PXR-mediated CYP3A4 induction by mGluR2 modulators. Bioorg. Med. Chem. Lett., 28, 2018
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5D5A
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![BU of 5d5a by Molmil](/molmil-images/mine/5d5a) | In meso in situ serial X-ray crystallography structure of the Beta2-adrenergic receptor at 100 K | 分子名称: | (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol, 1,4-BUTANEDIOL, ACETAMIDE, ... | 著者 | Huang, C.-Y, Olieric, V, Warshamanage, R, Liu, X, Kobilka, B, Kay Diederichs, K, Wang, M, Caffrey, M. | 登録日 | 2015-08-10 | 公開日 | 2016-01-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4826 Å) | 主引用文献 | In meso in situ serial X-ray crystallography of soluble and membrane proteins at cryogenic temperatures. Acta Crystallogr D Struct Biol, 72, 2016
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