6SEO
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![BU of 6seo by Molmil](/molmil-images/mine/6seo) | TEAD4 bound to a FAM181B peptide | 分子名称: | Protein FAM181B, Transcriptional enhancer factor TEF-3 | 著者 | Scheufler, C, Villard, F. | 登録日 | 2019-07-30 | 公開日 | 2019-11-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Identification of FAM181A and FAM181B as new interactors with the TEAD transcription factors. Protein Sci., 29, 2020
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2XIN
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1XIN
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8DPX
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![BU of 8dpx by Molmil](/molmil-images/mine/8dpx) | Preligand association structure of DR5 | 分子名称: | Tumor necrosis factor receptor superfamily member 10B | 著者 | Du, G, Zhao, L, Chou, J.J. | 登録日 | 2022-07-17 | 公開日 | 2023-02-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Autoinhibitory structure of preligand association state implicates a new strategy to attain effective DR5 receptor activation. Cell Res., 33, 2023
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6SUT
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![BU of 6sut by Molmil](/molmil-images/mine/6sut) | Crystal structure of phosphothreonine MCR-2 | 分子名称: | BROMIDE ION, GLYCEROL, Putative integral membrane protein, ... | 著者 | Hinchliffe, P, Spencer, J. | 登録日 | 2019-09-16 | 公開日 | 2020-06-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Resistance to the "last resort" antibiotic colistin: a single-zinc mechanism for phosphointermediate formation in MCR enzymes. Chem.Commun.(Camb.), 56, 2020
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7KGU
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![BU of 7kgu by Molmil](/molmil-images/mine/7kgu) | Structure of 2Q1-Fab, an antibody selective for IDH2R140Q-HLA-B*07:02 | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Miller, M.S, Aytenfisu, T.Y, Wright, K.M, Gabelli, S.B. | 登録日 | 2020-10-18 | 公開日 | 2021-06-23 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens. Nat Commun, 12, 2021
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7XGR
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7XDT
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6SB1
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![BU of 6sb1 by Molmil](/molmil-images/mine/6sb1) | Crystal structure of murine perforin-2 P2 domain crystal form 1 | 分子名称: | CHLORIDE ION, GLYCEROL, Macrophage-expressed gene 1 protein | 著者 | Ni, T, Ginger, L, Gilbert, R.J.C. | 登録日 | 2019-07-18 | 公開日 | 2020-02-05 | 最終更新日 | 2020-02-26 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity. Sci Adv, 6, 2020
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6SB3
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6SB4
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![BU of 6sb4 by Molmil](/molmil-images/mine/6sb4) | Crystal structure of murine perforin-2 P2 domain crystal form 2 | 分子名称: | Macrophage-expressed gene 1 protein | 著者 | Ni, T, Yu, X, Ginger, L, Gilbert, R.J.C. | 登録日 | 2019-07-18 | 公開日 | 2020-02-05 | 最終更新日 | 2020-02-26 | 実験手法 | X-RAY DIFFRACTION (3.17 Å) | 主引用文献 | Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity. Sci Adv, 6, 2020
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7XJF
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![BU of 7xjf by Molmil](/molmil-images/mine/7xjf) | Crystal structure of 6MW3211 Fab in complex with CD47 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Wang, J, Wang, R, Jiao, S, Wang, S, Zhang, J, Zhang, M, Wang, M. | 登録日 | 2022-04-16 | 公開日 | 2023-05-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Blockade of dual immune checkpoint inhibitory signals with a CD47/PD-L1 bispecific antibody for cancer treatment. Theranostics, 13, 2023
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7XIM
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6SB5
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1CUS
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2UZB
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![BU of 2uzb by Molmil](/molmil-images/mine/2uzb) | Crystal structure of human CDK2 complexed with a thiazolidinone inhibitor | 分子名称: | 4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-FURYL}-N-METHYLBENZENESULFONAMIDE, CELL DIVISION PROTEIN KINASE 2, CYCLIN-A2 | 著者 | Richardson, C.M, Dokurno, P, Murray, J.B, Surgenor, A.E. | 登録日 | 2007-04-27 | 公開日 | 2007-06-26 | 最終更新日 | 2019-04-03 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Discovery of a Potent Cdk2 Inhibitor with a Novel Binding Mode, Using Virtual Screening and Initial, Structure-Guided Lead Scoping. Bioorg.Med.Chem.Lett., 17, 2007
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2UZD
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![BU of 2uzd by Molmil](/molmil-images/mine/2uzd) | Crystal structure of human CDK2 complexed with a thiazolidinone inhibitor | 分子名称: | 4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZENESULFONAMIDE, CELL DIVISION PROTEIN KINASE 2, CYCLIN A2 | 著者 | Richardson, C.M, Dokurno, P, Murray, J.B, Surgenor, A.E. | 登録日 | 2007-04-27 | 公開日 | 2007-06-26 | 最終更新日 | 2019-04-03 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Discovery of a Potent Cdk2 Inhibitor with a Novel Binding Mode, Using Virtual Screening and Initial, Structure-Guided Lead Scoping. Bioorg.Med.Chem.Lett., 17, 2007
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2UZE
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![BU of 2uze by Molmil](/molmil-images/mine/2uze) | Crystal structure of human CDK2 complexed with a thiazolidinone inhibitor | 分子名称: | 4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZOIC ACID, CELL DIVISION PROTEIN KINASE 2, CYCLIN A2 | 著者 | Richardson, C.M, Dokurno, P, Murray, J.B, Surgenor, A.E. | 登録日 | 2007-04-27 | 公開日 | 2007-06-26 | 最終更新日 | 2019-04-03 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Discovery of a Potent Cdk2 Inhibitor with a Novel Binding Mode, Using Virtual Screening and Initial, Structure-Guided Lead Scoping. Bioorg.Med.Chem.Lett., 17, 2007
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2UZN
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![BU of 2uzn by Molmil](/molmil-images/mine/2uzn) | Crystal structure of human CDK2 complexed with a thiazolidinone inhibitor | 分子名称: | 4-{5-[(1Z)-1-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)ETHYL]-2-FURYL}BENZENESULFONAMIDE, CELL DIVISION PROTEIN KINASE 2 | 著者 | Richardson, C.M, Dokurno, P, Murray, J.B, Surgenor, A.E. | 登録日 | 2007-04-30 | 公開日 | 2007-06-26 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Discovery of a Potent Cdk2 Inhibitor with a Novel Binding Mode, Using Virtual Screening and Initial, Structure-Guided Lead Scoping. Bioorg.Med.Chem.Lett., 17, 2007
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2UZO
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![BU of 2uzo by Molmil](/molmil-images/mine/2uzo) | Crystal structure of human CDK2 complexed with a thiazolidinone inhibitor | 分子名称: | 4-{5-[(Z)-(2,4-DIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZENESULFONAMIDE, CELL DIVISION PROTEIN KINASE 2 | 著者 | Richardson, C.M, Dokurno, P, Murray, J.B, Surgenor, A.E. | 登録日 | 2007-04-30 | 公開日 | 2007-06-26 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Discovery of a Potent Cdk2 Inhibitor with a Novel Binding Mode, Using Virtual Screening and Initial, Structure-Guided Lead Scoping. Bioorg.Med.Chem.Lett., 17, 2007
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2UZL
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![BU of 2uzl by Molmil](/molmil-images/mine/2uzl) | Crystal structure of human CDK2 complexed with a thiazolidinone inhibitor | 分子名称: | 4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}-2-(TRIFLUOROMETHYL)BENZENESULFONAMIDE, CELL DIVISION PROTEIN KINASE 2, CYCLIN A2 | 著者 | Richardson, C.M, Dokurno, P, Murray, J.B, Surgenor, A.E. | 登録日 | 2007-04-30 | 公開日 | 2007-06-26 | 最終更新日 | 2019-04-03 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Discovery of a Potent Cdk2 Inhibitor with a Novel Binding Mode, Using Virtual Screening and Initial, Structure-Guided Lead Scoping. Bioorg.Med.Chem.Lett., 17, 2007
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2V0D
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![BU of 2v0d by Molmil](/molmil-images/mine/2v0d) | Crystal structure of human CDK2 complexed with a thiazolidinone inhibitor | 分子名称: | 2-IMINO-5-(1-PYRIDIN-2-YL-METH-(E)-YLIDENE)-1,3-THIAZOLIDIN-4-ONE, CELL DIVISION PROTEIN KINASE 2, CHLORIDE ION | 著者 | Richardson, C.M, Dokurno, P, Murray, J.B, Surgenor, A.E. | 登録日 | 2007-05-14 | 公開日 | 2007-06-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Discovery of a Potent Cdk2 Inhibitor with a Novel Binding Mode, Using Virtual Screening and Initial, Structure-Guided Lead Scoping. Bioorg.Med.Chem.Lett., 17, 2007
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1CUW
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![BU of 1cuw by Molmil](/molmil-images/mine/1cuw) | CUTINASE, G82A, A85F, V184I, A185L, L189F MUTANT | 分子名称: | CUTINASE | 著者 | Longhi, S, Cambillau, C. | 登録日 | 1995-11-16 | 公開日 | 1996-07-11 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Dynamics of Fusarium solani cutinase investigated through structural comparison among different crystal forms of its variants. Proteins, 26, 1996
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1CUE
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![BU of 1cue by Molmil](/molmil-images/mine/1cue) | CUTINASE, Q121L MUTANT | 分子名称: | CUTINASE | 著者 | Martinez, C, Cambillau, C. | 登録日 | 1995-11-16 | 公開日 | 1996-07-11 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Dynamics of Fusarium solani cutinase investigated through structural comparison among different crystal forms of its variants. Proteins, 26, 1996
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1CUC
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