8DPX

Preligand association structure of DR5

Summary for 8DPX

• Entry DOI: 10.2210/pdb8dpx/pdb
• NMR Information: BMRB: 31034
• Descriptor: Tumor necrosis factor receptor superfamily member 10B (1 entity in total)
• Functional Keywords: preligand association structure, autoinhibition state, apoptosis
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 3
• Total formula weight: 36697.93

Authors

Du, G.,Zhao, L.,Chou, J.J. (deposition date: 2022-07-17, release date: 2023-02-15)

• Primary citation: Du, G.,Zhao, L.,Zheng, Y.,Belfetmi, A.,Cai, T.,Xu, B.,Heyninck, K.,Van Den Heede, K.,Buyse, M.A.,Fontana, P.,Bowman, M.,Lin, L.L.,Wu, H.,Chou, J.J.; Autoinhibitory structure of preligand association state implicates a new strategy to attain effective DR5 receptor activation.; Cell Res., 33:131-146, 2023; PubMed: 36604598; DOI: 10.1038/s41422-022-00755-2

Experimental method

SOLUTION NMR