4HUQ
 
 | | Crystal Structure of a transporter | | 分子名称: | Energy-coupling factor transporter ATP-binding protein EcfA 1, Energy-coupling factor transporter ATP-binding protein EcfA 2, Energy-coupling factor transporter transmembrane protein EcfT, ... | | 著者 | Zhang, P, Xu, K, Zhang, M, Zhao, Q, Yu, F. | | 登録日 | 2012-11-03 | | 公開日 | 2013-04-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.998 Å) | | 主引用文献 | Crystal structure of a folate energy-coupling factor transporter from Lactobacillus brevis.
Nature, 497, 2013
|
|
3LAK
 | | Crystal structure of HIV-1 reverse transcriptase in complex with N1-heterocycle pyrimidinedione non-nucleoside inhibitor | | 分子名称: | 3-({3-[(2-amino-6-fluoropyridin-4-yl)methyl]-5-(1-methylethyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl}carbonyl)-5-methylbenzonitrile, CHLORIDE ION, HIV Reverse transcriptase, ... | | 著者 | Lansdon, E.B, Mitchell, M.L. | | 登録日 | 2010-01-06 | | 公開日 | 2010-02-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | N1-Heterocyclic pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
Bioorg.Med.Chem.Lett., 20, 2010
|
|
3LAM
 | | Crystal structure of HIV-1 reverse transcriptase in complex with N1-propyl pyrimidinedione non-nucleoside inhibitor | | 分子名称: | 3-methyl-5-{[5-(1-methylethyl)-2,6-dioxo-3-propyl-1,2,3,6-tetrahydropyrimidin-4-yl]carbonyl}benzonitrile, HIV Reverse transcriptase, SULFATE ION | | 著者 | Lansdon, E.B, Mitchell, M.L. | | 登録日 | 2010-01-06 | | 公開日 | 2010-02-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | | 主引用文献 | N1-Alkyl pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
Bioorg.Med.Chem.Lett., 20, 2010
|
|
3LAN
 | | Crystal structure of HIV-1 reverse transcriptase in complex with N1-butyl pyrimidinedione non-nucleoside inhibitor | | 分子名称: | 3-{[3-butyl-5-(1-methylethyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl]carbonyl}-5-methylbenzonitrile, HIV Reverse transcriptase, SULFATE ION | | 著者 | Lansdon, E.B, Mitchell, M.L. | | 登録日 | 2010-01-06 | | 公開日 | 2010-02-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | N1-Alkyl pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
Bioorg.Med.Chem.Lett., 20, 2010
|
|
6D74
 | |
8JGA
 | | Cryo-EM structure of Mi3 fused with FKBP | | 分子名称: | Peptidyl-prolyl cis-trans isomerase FKBP1A,2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase | | 著者 | Zhang, H.W, Kang, W, Xue, C. | | 登録日 | 2023-05-20 | | 公開日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | | 主引用文献 | Dynamic Metabolons Using Stimuli-Responsive Protein Cages.
J.Am.Chem.Soc., 146, 2024
|
|
8JGC
 | | Cryo-EM structure of Mi3 fused with LOV2 | | 分子名称: | LOV domain-containing protein,2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase | | 著者 | Zhang, H.W, Kang, W, Xue, C. | | 登録日 | 2023-05-20 | | 公開日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | | 主引用文献 | Dynamic Metabolons Using Stimuli-Responsive Protein Cages.
J.Am.Chem.Soc., 146, 2024
|
|
7VKA
 | | Crystal Structure of GH3.6 in complex with an inhibitor | | 分子名称: | ADENOSINE MONOPHOSPHATE, GLYCEROL, Indole-3-acetic acid-amido synthetase GH3.6, ... | | 著者 | Wang, N, Luo, M, Bao, H, Huang, H. | | 登録日 | 2021-09-29 | | 公開日 | 2022-08-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | | 主引用文献 | Chemical genetic screening identifies nalacin as an inhibitor of GH3 amido synthetase for auxin conjugation.
Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
5H19
 | | EED in complex with PRC2 allosteric inhibitor EED162 | | 分子名称: | 5-(furan-2-ylmethylamino)-9-(phenylmethyl)-8,10-dihydro-7H-[1,2,4]triazolo[3,4-a][2,7]naphthyridine-6-carbonitrile, Histone-lysine N-methyltransferase EZH2, Polycomb protein EED | | 著者 | Zhao, K, Zhao, M, Luo, X, Zhang, H. | | 登録日 | 2016-10-08 | | 公開日 | 2017-01-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED
PLoS ONE, 12, 2017
|
|
4Z7F
 | | Crystal structure of FolT bound with folic acid | | 分子名称: | FOLIC ACID, Folate ECF transporter | | 著者 | Zhao, Q, Wang, C.C, Wang, C.Y, Zhang, P. | | 登録日 | 2015-04-07 | | 公開日 | 2015-07-29 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.194 Å) | | 主引用文献 | Structures of FolT in substrate-bound and substrate-released conformations reveal a gating mechanism for ECF transporters
Nat Commun, 6, 2015
|
|
8GS9
 | | SARS-CoV-2 BA.2 spike RBD in complex bound with VacBB-551 | | 分子名称: | Heavy chain of VacBB-551, Light chain of VacBB-551, Spike glycoprotein | | 著者 | Liu, C.C, Ju, B, Shen, S.L, Zhang, Z. | | 登録日 | 2022-09-05 | | 公開日 | 2023-05-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | | 主引用文献 | Omicron BQ.1.1 and XBB.1 unprecedentedly escape broadly neutralizing antibodies elicited by prototype vaccination.
Cell Rep, 42, 2023
|
|
6KI1
 | |
6KI2
 | |
1F40
 | | SOLUTION STRUCTURE OF FKBP12 COMPLEXED WITH GPI-1046, A NEUROTROPHIC LIGAND | | 分子名称: | (2S)-[3-PYRIDYL-1-PROPYL]-1-[3,3-DIMETHYL-1,2-DIOXOPENTYL]-2-PYRROLIDINECARBOXYLATE, FK506 BINDING PROTEIN (FKBP12) | | 著者 | Sich, C, Improta, S, Cowley, D.J, Guenet, C, Merly, J.P, Teufel, M, Saudek, V. | | 登録日 | 2000-06-07 | | 公開日 | 2000-11-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a neurotrophic ligand bound to FKBP12 and its effects on protein dynamics.
Eur.J.Biochem., 267, 2000
|
|
7W29
 | |
7W28
 | |
7DSS
 | | Complex of FMDV and M8 Nab | | 分子名称: | M8 Nab, VP1 of O type FMDV capsid, VP2 of O-type FMDV capsid, ... | | 著者 | Dong, H, Liu, P. | | 登録日 | 2021-01-02 | | 公開日 | 2021-03-31 | | 最終更新日 | 2022-05-25 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural and molecular basis for foot-and-mouth disease virus neutralization by two potent protective antibodies.
Protein Cell, 13, 2022
|
|
7DST
 | | FMDV capsid in complex with M170 Nab | | 分子名称: | M170 Nab, VP1 of O type FMDV capsid, VP2 of O type FMDV capsid, ... | | 著者 | Dong, H, Liu, P. | | 登録日 | 2021-01-02 | | 公開日 | 2021-03-10 | | 最終更新日 | 2022-05-25 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural and molecular basis for foot-and-mouth disease virus neutralization by two potent protective antibodies.
Protein Cell, 13, 2022
|
|
5XSD
 | | XylFII-LytSN complex mutant - D103A | | 分子名称: | Periplasmic binding protein/LacI transcriptional regulator, Signal transduction histidine kinase, LytS | | 著者 | Li, J.X, Wang, C.Y, Zhang, P. | | 登録日 | 2017-06-13 | | 公開日 | 2017-08-02 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Molecular mechanism of environmental d-xylose perception by a XylFII-LytS complex in bacteria
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
5XSS
 | | XylFII molecule | | 分子名称: | Periplasmic binding protein/LacI transcriptional regulator, beta-D-xylopyranose | | 著者 | Li, J.X, Wang, C.Y, Zhang, P. | | 登録日 | 2017-06-15 | | 公開日 | 2017-08-02 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.093 Å) | | 主引用文献 | Molecular mechanism of environmental d-xylose perception by a XylFII-LytS complex in bacteria
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
5YYL
 | | Structure of Major Royal Jelly Protein 1 Oligomer | | 分子名称: | (3beta,14beta,17alpha)-ergosta-5,24(28)-dien-3-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Tian, W, Chen, Z. | | 登録日 | 2017-12-10 | | 公開日 | 2018-08-08 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Architecture of the native major royal jelly protein 1 oligomer.
Nat Commun, 9, 2018
|
|
7ENO
 | | Mutant strain M3 of foot-and-mouth disease virus type O | | 分子名称: | VP1 of O type FMDV capsid, VP2 of O type FMDV capsid, VP3 of O type FMDV capsid, ... | | 著者 | Dong, H, Lu, Y. | | 登録日 | 2021-04-18 | | 公開日 | 2021-06-02 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | | 主引用文献 | A Heat-Induced Mutation on VP1 of Foot-and-Mouth Disease Virus Serotype O Enhanced Capsid Stability and Immunogenicity.
J.Virol., 95, 2021
|
|
7ENP
 | | wild type of O type Foot-and-mouth disease virus | | 分子名称: | VP1 of O type FMDV capsid protein, VP2 of O type FMDV capsid protein, VP3 of O type FMDV capsid protein, ... | | 著者 | Dong, H, Lu, Y. | | 登録日 | 2021-04-18 | | 公開日 | 2021-06-02 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | A Heat-Induced Mutation on VP1 of Foot-and-Mouth Disease Virus Serotype O Enhanced Capsid Stability and Immunogenicity.
J.Virol., 95, 2021
|
|
7WP1
 | | Cryo-EM structure of SARS-CoV-2 Mu S6P trimer in complex with neutralizing antibody VacW-209 (local refinement) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, VacW-209 heavy chain, ... | | 著者 | Zheng, Q, Sun, H, Ju, B, Zhang, Z, Li, S, Xia, N. | | 登録日 | 2022-01-22 | | 公開日 | 2022-07-13 | | 実験手法 | ELECTRON MICROSCOPY (3.77 Å) | | 主引用文献 | Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209.
Cell Res., 32, 2022
|
|
7WON
 | | Cryo-EM structure of SARS-CoV-2 S2P trimer in complex with neutralizing antibody VacW-209 (local refinement) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, VacW-209 heavy chain, ... | | 著者 | Zheng, Q, Sun, H, Ju, B, Zhang, Z, Li, S, Xia, N. | | 登録日 | 2022-01-22 | | 公開日 | 2022-07-13 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209.
Cell Res., 32, 2022
|
|
