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4HQQ
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BU of 4hqq by Molmil
Crystal structure of RV144-elicited antibody CH58
分子名称: CH58 Fab heavy chain, CH58 Fab light chain
著者McLellan, J.S, Haynes, B.F, Kwong, P.D.
登録日2012-10-25
公開日2013-02-06
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
3U1S
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BU of 3u1s by Molmil
Crystal structure of human Fab PGT145, a broadly reactive and potent HIV-1 neutralizing antibody
分子名称: Fab PGT145 Heavy chain, Fab PGT145 Light chain, GLYCEROL, ...
著者Julien, J.-P, Diwanji, D, Burton, D.R, Wilson, I.A.
登録日2011-09-30
公開日2011-12-07
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3U46
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BU of 3u46 by Molmil
CH04H/CH02L P212121
分子名称: CH02 Light chain Fab, CH04 Heavy chain Fab
著者Louder, R, Pancera, M, McLellan, J.S, Kwong, P.D.
登録日2011-10-07
公開日2011-11-30
最終更新日2011-12-21
実験手法X-RAY DIFFRACTION (2.906 Å)
主引用文献Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3TCL
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BU of 3tcl by Molmil
Crystal Structure of HIV-1 Neutralizing Antibody CH04
分子名称: CH04 Heavy Chain Fab, CH04 Light Chain Fab, IMIDAZOLE
著者Louder, R.K, McLellan, J.S, Pancera, M, Yang, Y, Zhang, B, Bonsignori, M, Kwong, P.D.
登録日2011-08-09
公開日2011-11-30
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.906 Å)
主引用文献Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3U4B
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BU of 3u4b by Molmil
CH04H/CH02L Fab P4
分子名称: CH02 Light chain, CH04 Heavy chain
著者Pancera, M, Louder, R, Mclellan, J.S, KWong, P.D.
登録日2011-10-07
公開日2011-11-30
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.893 Å)
主引用文献Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3U36
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BU of 3u36 by Molmil
Crystal Structure of PG9 Fab
分子名称: PG9 Fab heavy chain, PG9 Fab light chain, SULFATE ION
著者McLellan, J.S, Kwong, P.D.
登録日2011-10-04
公開日2011-11-30
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.281 Å)
主引用文献Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3U2S
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BU of 3u2s by Molmil
Crystal Structure of PG9 Fab in Complex with V1V2 Region from HIV-1 strain ZM109
分子名称: (R,R)-2,3-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
著者McLellan, J.S, Pancera, M, Kwong, P.D.
登録日2011-10-04
公開日2011-11-30
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.797 Å)
主引用文献Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
7Z7C
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BU of 7z7c by Molmil
Broadly neutralizing DARPin bnD.8 in complex with the HIV-1 envelope variable loop 3 peptide V3 (BF520)
分子名称: 1,2-ETHANEDIOL, Broadly neutralizing DARPin bnD.8, Envelope glycoprotein gp160, ...
著者Mittl, P.R, Gloegl, M.
登録日2022-03-15
公開日2023-03-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization.
Nat.Struct.Mol.Biol., 30, 2023
5I8E
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BU of 5i8e by Molmil
Crystal Structure of Broadly Neutralizing HIV-1 Fusion Peptide-Targeting Antibody VRC34.01 Fab
分子名称: VRC34.01 Fab heavy chain, VRC34.01 Fab light chain, ZINC ION
著者Xu, K, Zhou, T, Liu, K, Kwong, P.D.
登録日2016-02-18
公開日2016-05-25
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.655 Å)
主引用文献Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody.
Science, 352, 2016
8AED
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BU of 8aed by Molmil
Broadly neutralizing DARPin bnD.9 in complex with the HIV-1 envelope variable loop 3 peptide V3 (BG505)
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Broadly neutralizing DARPin bnD.9, ...
著者Mittl, P, Gloegl, M.
登録日2022-07-13
公開日2023-08-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.17 Å)
主引用文献Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization.
Nat.Struct.Mol.Biol., 30, 2023
8VUZ
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BU of 8vuz by Molmil
L5A7 Fab bound to 28H6E11 anti-idiotype Fab
分子名称: 28H6E11 Fab Heavy Chain, 28H6E11 Fab Light Chain, L5A7 Fab Heavy Chain, ...
著者Olia, A.S, Morano, N.C, Kwong, P.D.
登録日2024-01-30
公開日2024-05-22
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.95 Å)
主引用文献Anti-idiotype isolation of a broad and potent influenza A virus-neutralizing human antibody.
Front Immunol, 15, 2024
8VVB
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BU of 8vvb by Molmil
Influenza antibody L5A7 Fab
分子名称: L5A7 Heavy Chain, L5A7 Light Chain
著者Harris, D.R, Olia, A.S, Kwong, P.D.
登録日2024-01-30
公開日2024-05-22
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Anti-idiotype isolation of a broad and potent influenza A virus-neutralizing human antibody.
Front Immunol, 15, 2024
8T7T
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BU of 8t7t by Molmil
CryoEM structure of the HisRS-like domain of human GCN2
分子名称: eIF-2-alpha kinase GCN2
著者Yin, J.Z, Keszei, A.F.A, Mazhab-Jafari, M.T, Sicheri, F.
登録日2023-06-21
公開日2024-03-13
最終更新日2024-09-25
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The HisRS-like domain of GCN2 is a pseudoenzyme that can bind uncharged tRNA.
Structure, 32, 2024
7MXD
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BU of 7mxd by Molmil
Cryo-EM structure of broadly neutralizing V2-apex-targeting antibody J038 in complex with HIV-1 Env
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC117 antibody heavy chain, ...
著者Zhou, T, Gao, F.
登録日2021-05-19
公開日2022-03-30
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Development of Neutralization Breadth against Diverse HIV-1 by Increasing Ab-Ag Interface on V2.
Adv Sci, 9, 2022
7N28
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BU of 7n28 by Molmil
Cryo-EM structure of broadly neutralizing V2-apex-targeting antibody J033 in complex with HIV-1 Env
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC117 antibody heavy chain, ...
著者Zhou, T, Gao, F.
登録日2021-05-28
公開日2022-04-06
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Development of Neutralization Breadth against Diverse HIV-1 by Increasing Ab-Ag Interface on V2.
Adv Sci, 9, 2022
5I8C
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BU of 5i8c by Molmil
Crystal Structure of HIV-1 Clade A BG505 Fusion Peptide (residue 512-520) in Complex with Broadly Neutralizing Antibody VRC34.01 Fab
分子名称: HIV-1 Clade A BG505 Fusion Peptide (residue 512-520), VRC34.01 Fab heavy chain, VRC34.01 Fab light chain
著者Xu, K, Zhou, T, Liu, K, Kwong, P.D.
登録日2016-02-18
公開日2016-05-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody.
Science, 352, 2016
5UBP
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BU of 5ubp by Molmil
TREX2 M-region
分子名称: 26S proteasome complex subunit SEM1, Leucine permease transcriptional regulator, Nuclear mRNA export protein THP1
著者Stewart, M, Gordon, J.
登録日2016-12-21
公開日2017-04-05
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the Sac3 RNA-binding M-region in the Saccharomyces cerevisiae TREX-2 complex.
Nucleic Acids Res., 45, 2017
5I8H
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BU of 5i8h by Molmil
Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer in Complex with V3 Loop-targeting Antibody PGT122 Fab and Fusion Peptide-targeting Antibody VRC34.01 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.664 gp120, ...
著者Xu, K, Zhou, T, Kwong, P.D.
登録日2016-02-18
公開日2016-05-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (4.301 Å)
主引用文献Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody.
Science, 352, 2016
2FDA
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BU of 2fda by Molmil
Crystal Structure of the Catalytic Domain of Human Coagulation Factor XIa in Complex with alpha-Ketothiazole Arginine Derived Ligand
分子名称: BICARBONATE ION, Coagulation factor XI, N~2~-(AMINOCARBONYL)-N~1~-{4-{[AMINO(IMINO)METHYL]AMINO}-1-[HYDROXY(1,3-THIAZOL-2-YL)METHYL]BUTYL}VALINAMIDE, ...
著者Jin, L, Pandey, P, Babine, R.E, Weaver, D.T, Abdel-Meguid, S.S, Strickler, J.E.
登録日2005-12-13
公開日2006-04-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Synthesis, SAR exploration, and X-ray crystal structures of factor XIa inhibitors containing an alpha-ketothiazole arginine
Bioorg.Med.Chem.Lett., 16, 2006
6B5R
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BU of 6b5r by Molmil
Structure of PfCSP peptide 21 with human antibody CIS42
分子名称: CIS42 Fab Heavy chain, CIS42 Fab Light chain, PfCSP peptide 21: ASN-PRO-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL-ASP-PRO-ASN
著者Pancera, M, Weidle, C.
登録日2017-09-29
公開日2018-03-21
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.775 Å)
主引用文献A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
Nat. Med., 24, 2018
6B5P
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BU of 6b5p by Molmil
Structure of PfCSP peptide 20 with human antibody CIS42
分子名称: CIS42 Fab Heavy chain, CIS42 Fab Light chain, pfCSP peptide 20: ASN-PRO-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL-ASP
著者Pancera, M, Weidle, C.
登録日2017-09-29
公開日2018-03-21
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.297 Å)
主引用文献A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
Nat. Med., 24, 2018
6B5M
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BU of 6b5m by Molmil
Structure of PfCSP peptide 21 with human protective antibody CIS43
分子名称: 1,2-ETHANEDIOL, CIS43 Fab Heavy chain, CIS43 Fab Light chain, ...
著者Pancera, M, Weidle, C.
登録日2017-09-29
公開日2018-03-21
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
Nat. Med., 24, 2018
6B5T
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BU of 6b5t by Molmil
Structure of PfCSP peptide 29 with human antibody CIS42
分子名称: AMMONIUM ION, CIS42 Fab Heavy chain, CIS42 Fab Light chain, ...
著者Pancera, M, Weidle, C.
登録日2017-09-29
公開日2018-03-21
最終更新日2018-04-25
実験手法X-RAY DIFFRACTION (2.222 Å)
主引用文献A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
Nat. Med., 24, 2018
6B5N
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BU of 6b5n by Molmil
Structure of PfCSP peptide 25 with human protective antibody CIS43
分子名称: CIS43 Fab Heavy chain, CIS43 Fab Light chain, pfCSP peptide 25: ASN-VAL-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL-ASP
著者Pancera, M, Weidle, C.
登録日2017-09-29
公開日2018-03-21
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.
Nat. Med., 24, 2018
9D93
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BU of 9d93 by Molmil
Mycobacteriophage Bxb1 tail tip - Composite map and model
分子名称: Major tail protein, Minor tail protein, Tapemeasure protein
著者Freeman, K.G.
登録日2024-08-20
公開日2024-09-25
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献Structure and infection dynamics of mycobacteriophage Bxb1
To Be Published

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件を2024-11-06に公開中

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