8TVY
| Cryo-EM structure of CPD lesion containing RNA Polymerase II elongation complex with Rad26 and Elf1 (closed state) | 分子名称: | DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | 登録日 | 2023-08-18 | 公開日 | 2024-01-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121, 2024
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2AFR
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2AFV
| The Crystal Structure of Putative Precorrin Isomerase CbiC in Cobalamin Biosynthesis | 分子名称: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CHLORIDE ION, HEXAETHYLENE GLYCOL, ... | 著者 | Xue, Y, Wei, Z. | 登録日 | 2005-07-26 | 公開日 | 2006-04-04 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The crystal structure of putative precorrin isomerase CbiC in cobalamin biosynthesis J.Struct.Biol., 153, 2006
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2B1N
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6VIL
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4QGU
| protein domain complex with ssDNA | 分子名称: | DNA (5'-D(P*AP*GP*GP*CP*CP*GP*GP*CP*GP*TP*GP*A)-3'), Gamma-interferon-inducible protein 16 | 著者 | Ni, X, Ru, H, Zhao, L, Shaw, N, Ding, W, Songying, O, Liu, Z.-J. | 登録日 | 2014-05-25 | 公開日 | 2015-06-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.545 Å) | 主引用文献 | New insights into the structural basis of DNA recognition by HINa and HINb domains of IFI16. J Mol Cell Biol, 8, 2016
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7JTP
| Crystal structure of Protac MS67 in complex with the WD repeat-containing protein 5 and pVHL:ElonginC:ElonginB | 分子名称: | Elongin-B, Elongin-C, GLYCEROL, ... | 著者 | Kottur, J, Jain, R, Aggarwal, A.K. | 登録日 | 2020-08-18 | 公開日 | 2021-10-06 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models. Sci Transl Med, 13, 2021
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7JTO
| Crystal structure of Protac MS33 in complex with the WD repeat-containing protein 5 and pVHL:ElonginC:ElonginB | 分子名称: | 1,2-ETHANEDIOL, 3-methyl-N-(11-{[2-(4-{[4'-(4-methylpiperazin-1-yl)-3'-{[6-oxo-4-(trifluoromethyl)-5,6-dihydropyridine-3-carbonyl]amino}[1,1'-biphenyl]-3-yl]methyl}piperazin-1-yl)ethyl]amino}-11-oxoundecanoyl)-L-valyl-(4R)-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}-L-prolinamide, Elongin-B, ... | 著者 | Kottur, J, Jain, R, Aggarwal, A.K. | 登録日 | 2020-08-18 | 公開日 | 2021-10-06 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models. Sci Transl Med, 13, 2021
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8H7Y
| Trans-3/4-proline-hydroxylase H11 with AKG and L-proline | 分子名称: | 2-OXOGLUTARIC ACID, FE (III) ION, PROLINE, ... | 著者 | Gong, W.M, Hu, X.Y. | 登録日 | 2022-10-21 | 公開日 | 2023-04-19 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Structures of L-proline trans-hydroxylase reveal the catalytic specificity and provide deeper insight into AKG-dependent hydroxylation. Acta Crystallogr D Struct Biol, 79, 2023
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8H7T
| Trans-3/4-proline-hydroxylase H11 apo structure | 分子名称: | CHLORIDE ION, Phytanoyl-CoA dioxygenase | 著者 | Gong, W.M, Hu, X.Y. | 登録日 | 2022-10-21 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Structures of L-proline trans-hydroxylase reveal the catalytic specificity and provide deeper insight into AKG-dependent hydroxylation. Acta Crystallogr D Struct Biol, 79, 2023
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8H7V
| Trans-3/4-proline-hydroxylase H11 with AKG | 分子名称: | 2-OXOGLUTARIC ACID, FE (III) ION, Phytanoyl-CoA dioxygenase | 著者 | Gong, W.M, Hu, X.Y. | 登録日 | 2022-10-21 | 公開日 | 2023-04-19 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Structures of L-proline trans-hydroxylase reveal the catalytic specificity and provide deeper insight into AKG-dependent hydroxylation. Acta Crystallogr D Struct Biol, 79, 2023
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8H81
| Trans-3/4-proline-hydroxylase H11 with 4-Hydroxyl-proline | 分子名称: | 4-HYDROXYPROLINE, Phytanoyl-CoA dioxygenase | 著者 | Gong, W.M, Hu, X.Y. | 登録日 | 2022-10-21 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Structures of L-proline trans-hydroxylase reveal the catalytic specificity and provide deeper insight into AKG-dependent hydroxylation. Acta Crystallogr D Struct Biol, 79, 2023
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8H85
| Trans-3/4-proline-hydroxylase H11 with 3-hydroxyl-proline | 分子名称: | 3-HYDROXYPROLINE, Phytanoyl-CoA dioxygenase | 著者 | Gong, W.M, Hu, X.Y. | 登録日 | 2022-10-21 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Structures of L-proline trans-hydroxylase reveal the catalytic specificity and provide deeper insight into AKG-dependent hydroxylation. Acta Crystallogr D Struct Biol, 79, 2023
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8IRZ
| Carbon Sulfoxide lyase | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, Probable hercynylcysteine sulfoxide lyase | 著者 | Gong, W.M, Wei, L.L, Liu, L. | 登録日 | 2023-03-20 | 公開日 | 2024-03-06 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | 主引用文献 | Structure of mycobacterial ergothioneine-biosynthesis C-S lyase EgtE. J.Biol.Chem., 300, 2024
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8IRY
| Carbon Sulfoxide lyase | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, PYRUVIC ACID, Probable hercynylcysteine sulfoxide lyase | 著者 | Gong, W.M, Wei, L.L, Liu, L. | 登録日 | 2023-03-20 | 公開日 | 2024-03-06 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structure of mycobacterial ergothioneine-biosynthesis C-S lyase EgtE. J.Biol.Chem., 300, 2024
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8IS0
| Carbon Sulfoxide lyase - Y106F | 分子名称: | 2-AMINO-ACRYLIC ACID, PYRIDOXAL-5'-PHOSPHATE, Probable hercynylcysteine sulfoxide lyase | 著者 | Gong, W.M, Wei, L.L, Liu, L. | 登録日 | 2023-03-20 | 公開日 | 2024-03-06 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | 主引用文献 | Structure of mycobacterial ergothioneine-biosynthesis C-S lyase EgtE. J.Biol.Chem., 300, 2024
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8DS8
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2B1M
| Crystal structure of a papain-fold protein without the catalytic cysteine from seeds of Pachyrhizus erosus | 分子名称: | DI(HYDROXYETHYL)ETHER, SPE31, TETRAETHYLENE GLYCOL, ... | 著者 | Zhang, M, Wei, Z, Chang, S. | 登録日 | 2005-09-16 | 公開日 | 2006-10-03 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of a papain-fold protein without the catalytic residue: a novel member in the cysteine proteinase family J.Mol.Biol., 358, 2006
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8G05
| Cryo-EM structure of an orphan GPCR-Gi protein signaling complex | 分子名称: | 6-(octylamino)pyrimidine-2,4(3H,5H)-dione, CHOLESTEROL, G-protein coupled receptor 84, ... | 著者 | Zhang, X, Wang, Y.J, Li, X, Liu, G.B, Gong, W.M, Zhang, C. | 登録日 | 2023-01-31 | 公開日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Pro-phagocytic function and structural basis of GPR84 signaling. Nat Commun, 14, 2023
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2N51
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2MVN
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2MVM
| Solution structure of eEF1Bdelta CAR domain | 分子名称: | Elongation factor 1-delta | 著者 | Wu, H, Feng, Y. | 登録日 | 2014-10-09 | 公開日 | 2015-02-04 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Evolutionarily Conserved Binding of Translationally Controlled Tumor Protein to Eukaryotic Elongation Factor 1B. J.Biol.Chem., 290, 2015
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1QT1
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3L6A
| Crystal structure of the C-terminal region of Human p97 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, Eukaryotic translation initiation factor 4 gamma 2, ... | 著者 | Fan, S. | 登録日 | 2009-12-23 | 公開日 | 2010-04-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the C-terminal region of human p97/DAP5. Proteins, 78, 2010
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4NXF
| Crystal structure of iLOV-I486(2LT) at pH 8.0 | 分子名称: | FLAVIN MONONUCLEOTIDE, Phototropin-2 | 著者 | Wang, J, Liu, X, Li, J. | 登録日 | 2013-12-09 | 公開日 | 2014-09-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.766 Å) | 主引用文献 | Significant expansion of fluorescent protein sensing ability through the genetic incorporation of superior photo-induced electron-transfer quenchers. J.Am.Chem.Soc., 136, 2014
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