8GWF
| A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Helicase, Non-structural protein 7, ... | 著者 | Yan, L.Y, Huang, Y.C, Rao, Z.H, Lou, Z.Y. | 登録日 | 2022-09-17 | 公開日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | 主引用文献 | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
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8GWG
| A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Helicase, Non-structural protein 7, ... | 著者 | Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. | 登録日 | 2022-09-17 | 公開日 | 2022-12-14 | 実験手法 | ELECTRON MICROSCOPY (3.37 Å) | 主引用文献 | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
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8GWN
| A mechanism for SARS-CoV-2 RNA capping and its inhibitor of AT-527 | 分子名称: | Helicase, Non-structural protein 7, Non-structural protein 8, ... | 著者 | Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. | 登録日 | 2022-09-17 | 公開日 | 2022-12-14 | 最終更新日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | 主引用文献 | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
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8GWI
| A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Helicase, Non-structural protein 7, ... | 著者 | Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. | 登録日 | 2022-09-17 | 公開日 | 2022-12-14 | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | 主引用文献 | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
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6CTE
| 77Se-NMR probes the protein environment of selenomethionine | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ... | 著者 | Chen, Q, Rozovsky, S. | 登録日 | 2018-03-22 | 公開日 | 2019-07-10 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | 77Se NMR Probes the Protein Environment of Selenomethionine. J.Phys.Chem.B, 124, 2020
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8GW1
| A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors | 分子名称: | Helicase, MANGANESE (II) ION, Non-structural protein 7, ... | 著者 | Yan, L, Rao, Z, Lou, Z. | 登録日 | 2022-09-16 | 公開日 | 2023-10-25 | 最終更新日 | 2024-01-24 | 実験手法 | ELECTRON MICROSCOPY (3.31 Å) | 主引用文献 | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
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8GWM
| SARS-CoV-2 E-RTC bound with MMP-nsp9 and GMPPNP | 分子名称: | 2'-deoxy-2'-fluoro-2'-methyluridine 5'-(trihydrogen diphosphate), Helicase, Non-structural protein 7, ... | 著者 | Yan, L.M, Rao, Z.H, Lou, Z.Y. | 登録日 | 2022-09-17 | 公開日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (2.64 Å) | 主引用文献 | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
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8GWK
| SARS-CoV-2 RNA E-RTC complex with RMP-nsp9 and GMPPNP | 分子名称: | Helicase, MAGNESIUM ION, Non-structural protein 7, ... | 著者 | Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. | 登録日 | 2022-09-17 | 公開日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (2.72 Å) | 主引用文献 | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
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6CPZ
| Selenomethionine mutant (I6Sem) of protein GB1 examined by X-ray diffraction | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Immunoglobulin G-binding protein G, ... | 著者 | Chen, Q, Rozovsky, S. | 登録日 | 2018-03-14 | 公開日 | 2019-07-10 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | 主引用文献 | 77Se NMR Probes the Protein Environment of Selenomethionine. J.Phys.Chem.B, 124, 2020
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6OC0
| Crystal structure of human DHODH with OSU-03012 | 分子名称: | Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ... | 著者 | Durst, M.A, Lavie, A. | 登録日 | 2019-03-21 | 公開日 | 2019-11-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Metabolic Modifier Screen Reveals Secondary Targets of Protein Kinase Inhibitors within Nucleotide Metabolism. Cell Chem Biol, 27, 2020
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3RZ3
| Human Cdc34 E2 in complex with CC0651 inhibitor | 分子名称: | 4,5-dideoxy-5-(3',5'-dichlorobiphenyl-4-yl)-4-[(methoxyacetyl)amino]-L-arabinonic acid, Ubiquitin-conjugating enzyme E2 R1 | 著者 | Ceccarelli, D.F, Webb, D.R, Sicheri, F. | 登録日 | 2011-05-11 | 公開日 | 2011-07-06 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | An allosteric inhibitor of the human cdc34 ubiquitin conjugating enzyme Cell(Cambridge,Mass.), 145, 2011
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6CNE
| Selenomethionine variant (V29SeM) of protein GB1 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Immunoglobulin G-binding protein G, PHOSPHATE ION | 著者 | Chen, Q. | 登録日 | 2018-03-08 | 公開日 | 2019-07-10 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | 77Se NMR Probes the Protein Environment of Selenomethionine. J.Phys.Chem.B, 124, 2020
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6CHE
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6C9O
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5GT2
| Crystal Structure and Biochemical Features of dye-decolorizing peroxidase YfeX from Escherichia coli O157 | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, Probable deferrochelatase/peroxidase YfeX | 著者 | Ma, Y.L, Yuan, Z.G, Liu, S, Wang, J.X, Gu, L.C, Liu, X.H. | 登録日 | 2016-08-18 | 公開日 | 2017-02-08 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.093 Å) | 主引用文献 | Crystal structure and biochemical features of dye-decolorizing peroxidase YfeX from Escherichia coli O157 Asp(143) and Arg(232) play divergent roles toward different substrates Biochem. Biophys. Res. Commun., 484, 2017
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7TUU
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7UU9
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3GFE
| Crystal Structure of p38a Mitogen-Activated Protein Kinase in Complex with a Pyrazolopyridinone Inhibitor | 分子名称: | Mitogen-activated protein kinase 14, N-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamide | 著者 | Mohr, C, Jordan, S. | 登録日 | 2009-02-26 | 公開日 | 2009-07-14 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Part 1: Structure-Activity Relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38alpha mitogen-activated protein kinase. Bioorg.Med.Chem.Lett., 19, 2009
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8HLO
| Crystal structure of ASAP1-SH3 and MICAL1-PRM complex | 分子名称: | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1, Proline rich motif from MICAL1, ... | 著者 | Niu, F, Wei, Z, Yu, C. | 登録日 | 2022-11-30 | 公開日 | 2023-02-22 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.168 Å) | 主引用文献 | Crystal Structure of the SH3 Domain of ASAP1 in Complex with the Proline Rich Motif (PRM) of MICAL1 Reveals a Unique SH3/PRM Interaction Mode. Int J Mol Sci, 24, 2023
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4QNC
| Crystal structure of a SemiSWEET in an occluded state | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, PENTADECANE, chemical transport protein | 著者 | Yan, X, Yuyong, T, Liang, F, Perry, K. | 登録日 | 2014-06-17 | 公開日 | 2014-09-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.388 Å) | 主引用文献 | Structures of bacterial homologues of SWEET transporters in two distinct conformations. Nature, 515, 2014
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4QND
| Crystal structure of a SemiSWEET | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Chemical transport protein, ... | 著者 | Yan, X, Yuyong, T, Liang, F, Perry, K. | 登録日 | 2014-06-17 | 公開日 | 2014-09-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | 主引用文献 | Structures of bacterial homologues of SWEET transporters in two distinct conformations. Nature, 515, 2014
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8GOY
| SulE P44R | 分子名称: | 5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methyl-pyrazole-4-carboxylic acid, Alpha/beta fold hydrolase, GLYCEROL | 著者 | Liu, B, He, J, Ran, T, Wang, W. | 登録日 | 2022-08-25 | 公開日 | 2023-08-02 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.784 Å) | 主引用文献 | Crystal structures of herbicide-detoxifying esterase reveal a lid loop affecting substrate binding and activity. Nat Commun, 14, 2023
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8GP0
| crystal structure of SulE | 分子名称: | Alpha/beta fold hydrolase, CITRIC ACID, GLYCEROL | 著者 | Liu, B, Ran, T, wang, W, He, J. | 登録日 | 2022-08-25 | 公開日 | 2023-08-02 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | 主引用文献 | Crystal structures of herbicide-detoxifying esterase reveal a lid loop affecting substrate binding and activity. Nat Commun, 14, 2023
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8GOL
| crystal structure of SulE | 分子名称: | 2-[(4-chloranyl-6-methoxy-pyrimidin-2-yl)carbamoylsulfamoyl]benzoic acid, Alpha/beta fold hydrolase, GLYCEROL | 著者 | Liu, B, Ran, T, Wang, W, He, J. | 登録日 | 2022-08-25 | 公開日 | 2023-08-02 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structures of herbicide-detoxifying esterase reveal a lid loop affecting substrate binding and activity. Nat Commun, 14, 2023
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5HXB
| Cereblon in complex with DDB1, CC-885, and GSPT1 | 分子名称: | 1-(3-chloro-4-methylphenyl)-3-({2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-5-yl}methyl)urea, DNA damage-binding protein 1, Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, ... | 著者 | Chamberlain, P.P, Matyskiela, M, Pagarigan, B. | 登録日 | 2016-01-30 | 公開日 | 2016-06-29 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase. Nature, 535, 2016
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