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8GWH
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BU of 8gwh by Molmil
PTPN21 PTP domain C1108S mutant in complex with SRC pTyr530 peptide
分子名称: SRC pTyr530 peptide, Tyrosine-protein phosphatase non-receptor type 21
著者Chen, L, Zheng, Y.Y, Zhou, C.
登録日2022-09-17
公開日2023-09-20
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural analysis of PTPN21 reveals a dominant-negative effect of the FERM domain on its phosphatase activity.
Sci Adv, 10, 2024
3RL7
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BU of 3rl7 by Molmil
Crystal structure of hDLG1-PDZ1 complexed with APC
分子名称: 11-mer peptide from Adenomatous polyposis coli protein, Disks large homolog 1
著者Zhang, Z, Li, H, Wu, G.
登録日2011-04-19
公開日2011-12-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular basis for the recognition of adenomatous polyposis coli by the Discs Large 1 protein.
Plos One, 6, 2011
3RES
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BU of 3res by Molmil
Crystal structure of E coli Hfq in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Protein hfq
著者Wang, W.W, Wu, J.H, Shi, Y.Y.
登録日2011-04-05
公開日2011-10-19
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Cooperation of Escherichia coli Hfq hexamers in DsrA binding.
Genes Dev., 25, 2011
3RGQ
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BU of 3rgq by Molmil
Crystal Structure of PTPMT1 in complex with PI(5)P
分子名称: (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,4,6-tetrahydroxy-5-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dibutanoate, Protein-tyrosine phosphatase mitochondrial 1
著者Xiao, J, Engel, J.L.
登録日2011-04-08
公開日2011-07-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis.
Proc.Natl.Acad.Sci.USA, 108, 2011
6BHX
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BU of 6bhx by Molmil
B. subtilis SsbA with DNA
分子名称: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Single-stranded DNA-binding protein A
著者Dubiel, K.D, Myers, A.R, Satyshur, K.A, Keck, J.L.
登録日2017-10-31
公開日2018-12-19
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.936 Å)
主引用文献Structural Mechanisms of Cooperative DNA Binding by Bacterial Single-Stranded DNA-Binding Proteins.
J. Mol. Biol., 431, 2019
8GXE
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BU of 8gxe by Molmil
PTPN21 FERM PTP complex
分子名称: CHLORIDE ION, Tyrosine-protein phosphatase non-receptor type 21
著者Chen, L, Zheng, Y.Y, Zhou, C.
登録日2022-09-19
公開日2023-09-27
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural analysis of PTPN21 reveals a dominant-negative effect of the FERM domain on its phosphatase activity.
Sci Adv, 10, 2024
7JWL
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BU of 7jwl by Molmil
Crystal Structure of Pseudomonas aeruginosa Penicillin Binding Protein 3 (PAE-PBP3) bound to ETX0462
分子名称: CHLORIDE ION, ETX0462 (Bound form), Peptidoglycan D,D-transpeptidase FtsI
著者Mayclin, S.J, Abendroth, J, Horanyi, P.S, Sylvester, M, Wu, X, Shapiro, A, Moussa, S, Durand-Reville, T.F.
登録日2020-08-25
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Rational design of a new antibiotic class for drug-resistant infections.
Nature, 597, 2021
4L7I
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BU of 4l7i by Molmil
Crystal structure of S-Adenosylmethionine synthase from Sulfolobus solfataricus complexed with SAM and PPi
分子名称: DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
著者Wang, F, Hurley, K.A, Helmich, K.E, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2013-06-13
公開日2013-07-03
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.189 Å)
主引用文献Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus.
Febs J., 281, 2014
3RL8
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BU of 3rl8 by Molmil
Crystal structure of hDLG1-PDZ2 complexed with APC
分子名称: 11-mer peptide from Adenomatous polyposis coli protein, Disks large homolog 1
著者Zhang, Z, Li, H, Wu, G.
登録日2011-04-19
公開日2011-12-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular basis for the recognition of adenomatous polyposis coli by the Discs Large 1 protein.
Plos One, 6, 2011
4KVN
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BU of 4kvn by Molmil
Crystal structure of Fab 39.29 in complex with Influenza Hemagglutinin A/Perth/16/2009 (H3N2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Fong, R, Swem, L.R, Lupardus, P.J.
登録日2013-05-22
公開日2013-08-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A Novel In vivo Human Plasmablast Enrichment Technique Allows Rapid Identification of Therapeutic Anti-Influenza A Antibodies
Cell Host Microbe, 14, 2013
7X08
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BU of 7x08 by Molmil
S protein of SARS-CoV-2 in complex with 2G1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, ...
著者Guo, Y.Y, Zhang, Y.Y, Zhou, Q.
登録日2022-02-21
公開日2022-03-09
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Broad ultra-potent neutralization of SARS-CoV-2 variants by monoclonal antibodies specific to the tip of RBD.
Cell Discov, 8, 2022
3RGO
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BU of 3rgo by Molmil
Crystal Structure of PTPMT1
分子名称: Protein-tyrosine phosphatase mitochondrial 1, SULFATE ION
著者Xiao, J, Engel, J.L.
登録日2011-04-08
公開日2011-07-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.928 Å)
主引用文献Structural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis.
Proc.Natl.Acad.Sci.USA, 108, 2011
7LDG
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BU of 7ldg by Molmil
Crystal structure of the MEILB2-BRCA2 complex
分子名称: Breast cancer type 2 susceptibility protein, Heat shock factor 2-binding protein
著者Nandakumar, J, Pendlebury, D.F.
登録日2021-01-13
公開日2021-08-11
最終更新日2021-08-25
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Structure of a meiosis-specific complex central to BRCA2 localization at recombination sites.
Nat.Struct.Mol.Biol., 28, 2021
3UA0
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BU of 3ua0 by Molmil
N-Terminal Domain of Bombyx mori Fibroin Mediates the Assembly of Silk in Response to pH Decrease
分子名称: Fibroin heavy chain
著者He, Y.-X, Zhang, N.-N, Chen, B.-Y, Li, W.-F, Chen, Y.-X, Zhou, C.-Z.
登録日2011-10-20
公開日2012-03-28
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献N-Terminal Domain of Bombyx mori Fibroin Mediates the Assembly of Silk in Response to pH Decrease.
J.Mol.Biol., 418, 2012
4K0B
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BU of 4k0b by Molmil
Crystal structure of S-Adenosylmethionine synthetase from Sulfolobus solfataricus complexed with SAM and PPi
分子名称: DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
著者Wang, F, Hurley, K.A, Helmich, K.E, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2013-04-03
公開日2013-05-01
最終更新日2014-10-08
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus.
Febs J., 281, 2014
4L2Z
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BU of 4l2z by Molmil
Crystal structure of S-Adenosylmethionine synthetase from Sulfolobus solfataricus complexed with SAE and PPi
分子名称: DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
著者Wang, F, Hurley, K.A, Helmich, K.E, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2013-06-05
公開日2013-06-19
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.494 Å)
主引用文献Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus.
Febs J., 281, 2014
7K9A
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BU of 7k9a by Molmil
Crystal Structure of P. aeruginosa LpxC with N-Hydroxyformamide inhibitor
分子名称: DIMETHYL SULFOXIDE, GLYCEROL, N-hydroxy-N-[(1R)-2-{5-[(4-{[2-(hydroxymethyl)-1H-imidazol-1-yl]methyl}phenyl)ethynyl]-1H-benzotriazol-1-yl}-1-(methylsulfanyl)ethyl]formamide, ...
著者Sacco, M, Chen, Y.
登録日2020-09-29
公開日2020-11-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献N-Hydroxyformamide LpxC inhibitors, their in vivo efficacy in a mouse Escherichia coli infection model, and their safety in a rat hemodynamic assay.
Bioorg.Med.Chem., 28, 2020
4QVC
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BU of 4qvc by Molmil
E.coli Hfq in complex with RNA Aus
分子名称: RNA (5'-R(*AP*U*AP*AP*CP*UP*A)-3'), RNA-binding protein Hfq
著者Wang, L.J, Wang, W.W, Li, F.D, Wu, J.H, Gong, Q.G, Shi, Y.Y.
登録日2014-07-14
公開日2015-05-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural insights into the recognition of the internal A-rich linker from OxyS sRNA by Escherichia coli Hfq
Nucleic Acids Res., 43, 2015
6S50
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BU of 6s50 by Molmil
scdSav(SARK)mv2 - Engineering Single-Chain Dimeric Streptavidin as Host for Artificial Metalloenzymes
分子名称: GLYCEROL, SULFATE ION, Streptavidin, ...
著者Rebelein, J.G.
登録日2019-06-29
公開日2019-09-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Breaking Symmetry: Engineering Single-Chain Dimeric Streptavidin as Host for Artificial Metalloenzymes.
J.Am.Chem.Soc., 141, 2019
6LYC
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BU of 6lyc by Molmil
Crystal structure of the NOD SIRPa complex with D4-2
分子名称: ACETIC ACID, D4-2, SIRPa of the NOD mouse strain
著者Murata, Y, Matsuda, M, Nakagawa, A, Matozaki, T.
登録日2020-02-14
公開日2020-07-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Macrocyclic Peptide-Mediated Blockade of the CD47-SIRP alpha Interaction as a Potential Cancer Immunotherapy.
Cell Chem Biol, 27, 2020
7Y53
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BU of 7y53 by Molmil
The cryo-EM structure of human ERAD retro-translocation complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, Derlin-1, Transitional endoplasmic reticulum ATPase
著者Cao, Y, Rao, B, Wang, Q, Yao, D, Xia, Y, Li, W, Li, S, Shen, Y.
登録日2022-06-16
公開日2023-10-18
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.61 Å)
主引用文献The cryo-EM structure of the human ERAD retrotranslocation complex.
Sci Adv, 9, 2023
7Y59
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BU of 7y59 by Molmil
The cryo-EM structure of human ERAD retro-translocation complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Derlin-1, ...
著者Cao, Y, Rao, B, Wang, Q, Yao, D, Xia, Y, Li, W, Li, S, Shen, Y.
登録日2022-06-16
公開日2023-10-18
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (4.51 Å)
主引用文献The cryo-EM structure of the human ERAD retrotranslocation complex.
Sci Adv, 9, 2023
7Y4W
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BU of 7y4w by Molmil
The cryo-EM structure of human ERAD retro-translocation complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, Derlin-1, Transitional endoplasmic reticulum ATPase
著者Cao, Y, Rao, B, Wang, Q, Yao, D, Xia, Y, Li, W, Li, S, Shen, Y.
登録日2022-06-16
公開日2023-10-18
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.67 Å)
主引用文献The cryo-EM structure of the human ERAD retrotranslocation complex.
Sci Adv, 9, 2023
5Y1U
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BU of 5y1u by Molmil
Crystal structure of RBBP4 bound to AEBP2 RRK motif
分子名称: Histone-binding protein RBBP4, SULFATE ION, Zinc finger protein AEBP2
著者Sun, A, Li, F, Wu, J, Shi, Y.
登録日2017-07-21
公開日2018-04-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.141 Å)
主引用文献Structural and biochemical insights into human zinc finger protein AEBP2 reveals interactions with RBBP4
Protein Cell, 2017
4QVD
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BU of 4qvd by Molmil
E.coli Hfq in complex with RNA Ads
分子名称: RNA (5'-R(*AP*AP*CP*UP*AP*AP*A)-3'), RNA-binding protein Hfq
著者Wang, L.J, Wang, W.W, Li, F.D, Wu, J.H, Gong, Q.G, Shi, Y.Y.
登録日2014-07-14
公開日2015-05-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.972 Å)
主引用文献Structural insights into the recognition of the internal A-rich linker from OxyS sRNA by Escherichia coli Hfq
Nucleic Acids Res., 43, 2015

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