5JRR
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![BU of 5jrr by Molmil](/molmil-images/mine/5jrr) | Crystal structure of native laccase from Thermus thermophilus HB27 | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, COPPER (II) ION, ... | 著者 | Diaz-Vilchis, A, Ruiz-Arellano, R.R, Rosas-Benitez, E, Rudino-Pinera, E. | 登録日 | 2016-05-06 | 公開日 | 2017-05-10 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Preserving metallic sites affected by radiation damage: the CuT2 case in Thermus thermophilus multicopper oxidase To be Published
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4RD7
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![BU of 4rd7 by Molmil](/molmil-images/mine/4rd7) | The crystal structure of a Cupin 2 conserved barrel domain protein from Salinispora arenicola CNS-205 | 分子名称: | Cupin 2 conserved barrel domain protein, GLYCEROL, SULFATE ION | 著者 | Tan, K, Gu, M, Clancy, S, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2014-09-18 | 公開日 | 2014-10-01 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (1.571 Å) | 主引用文献 | The crystal structure of a Cupin 2 conserved barrel domain protein from Salinispora arenicola CNS-205 To be Published
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5JSV
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![BU of 5jsv by Molmil](/molmil-images/mine/5jsv) | tRNA guanine Transglycosylase (TGT) in co-crystallized complex with 6-amino-2-((((3aR,4R,6R,6aR)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl)amino)-1H-imidazo[4,5-g]quinazolin-8(7H)-one | 分子名称: | CHLORIDE ION, GLYCEROL, Queuine tRNA-ribosyltransferase, ... | 著者 | Ehrmann, F.R, Nguyen, D, Heine, A, Klebe, G. | 登録日 | 2016-05-09 | 公開日 | 2017-05-24 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.17 Å) | 主引用文献 | Application of carbohydrates based lin-benzoguanines in a solvent-exposed subpocket of the tRNA-modifying Enzyme TGT To be Published
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4QUR
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![BU of 4qur by Molmil](/molmil-images/mine/4qur) | Crystal Structure of stachydrine demethylase in complex with cyanide, oxygen, and N-methyl proline in a new orientation | 分子名称: | 1-methyl-L-proline, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, COBALT HEXAMMINE(III), ... | 著者 | Agarwal, R, Andi, B, Gizzi, A, Bonanno, J.B, Almo, S.C, Orville, A.M. | 登録日 | 2014-07-11 | 公開日 | 2015-07-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.759 Å) | 主引用文献 | Tracking photoelectron induced in-crystallo enzyme catalysis To be Published
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4QPP
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![BU of 4qpp by Molmil](/molmil-images/mine/4qpp) | The Crystal Structure of Human HMT1 hnRNP methyltransferase-like protein 6 in complex with compound DS-421 (2-{4-[3-CHLORO-2-(2-METHOXYPHENYL)-1H-INDOL-5-YL]PIPERIDIN-1-YL}-N-METHYLETHANAMINE | 分子名称: | 2-{4-[3-chloro-2-(2-methoxyphenyl)-1H-indol-5-yl]piperidin-1-yl}-N-methylethanamine, POLY-UNK, Protein arginine N-methyltransferase 6, ... | 著者 | Dong, A, Zeng, H, Smil, D, Walker, J.R, He, H, Eram, M, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Vedadi, M, Brown, P.J, Wu, H, Structural Genomics Consortium (SGC) | 登録日 | 2014-06-24 | 公開日 | 2014-08-20 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | The Crystal Structure of Human HMT1
hnRNP methyltransferase-like protein 6 in complex with compound DS-421 To be Published
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5JVB
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![BU of 5jvb by Molmil](/molmil-images/mine/5jvb) | 1.95A resolution structure of PtxB from Trichodesmium erythraeum IMS101 in complex with phosphite | 分子名称: | PHOSPHONATE, Phosphonate ABC transporter, periplasmic phosphonate-binding protein | 著者 | Bisson, C, Adams, N.B.P, Polyviou, D, Bibby, T.S, Hunter, C.N, Hitchcock, A. | 登録日 | 2016-05-11 | 公開日 | 2017-11-29 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | The molecular basis of phosphite and hypophosphite recognition by ABC-transporters. Nat Commun, 8, 2017
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8BGC
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![BU of 8bgc by Molmil](/molmil-images/mine/8bgc) | Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with compound 2 (AA-CS-9-003) | 分子名称: | 5-[(phenylmethyl)amino]pyrimido[4,5-c]quinoline-8-carboxylic acid, Casein kinase II subunit alpha, SULFATE ION | 著者 | Kraemer, A, Axtman, A.D, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2022-10-27 | 公開日 | 2022-11-23 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Discovery of a Potent and Selective Naphthyridine-Based Chemical Probe for Casein Kinase 2. Acs Med.Chem.Lett., 14, 2023
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5JX9
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![BU of 5jx9 by Molmil](/molmil-images/mine/5jx9) | Crystal structure of laccase from Thermus thermophilus HB27 (Cu(II)-cyclophanes, 5 min) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, COPPER (II) ION, Laccase | 著者 | Diaz-Vilchis, A, Ruiz-Arellano, R.R, Rosas-Benitez, E, Rudino-Pinera, E. | 登録日 | 2016-05-12 | 公開日 | 2017-06-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.599 Å) | 主引用文献 | Preserving metallic sites affected by radiation damage: the CuT2 case in Thermus thermophilus multicopper oxidase To be Published
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8R7G
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![BU of 8r7g by Molmil](/molmil-images/mine/8r7g) | Crystal structure of the kinase domain of ACVR1 (ALK2) with M4K2234 | 分子名称: | 2-fluoranyl-6-methoxy-4-[4-methyl-5-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pyridin-3-yl]benzamide, Activin receptor type I | 著者 | Williams, E.P, Cros, J, Ensan, D, Smil, D, Edwards, A.M, O'Meara, J.A, Fernandez-Cid, A, Isaac, M.B, Al-awar, R, Bullock, A.N. | 登録日 | 2023-11-24 | 公開日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Targeting ALK2: An Open Science Approach to Developing Therapeutics for the Treatment of Diffuse Intrinsic Pontine Glioma. J.Med.Chem., 63, 2020
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7OSM
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![BU of 7osm by Molmil](/molmil-images/mine/7osm) | Intermediate translocation complex of 80 S.cerevisiae ribosome with eEF2 and ligands | 分子名称: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0, ... | 著者 | Djumagulov, M, Jenner, L, Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | 登録日 | 2021-06-09 | 公開日 | 2021-12-08 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Accuracy mechanism of eukaryotic ribosome translocation. Nature, 600, 2021
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5JWD
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![BU of 5jwd by Molmil](/molmil-images/mine/5jwd) | Crystal structure of H-2Db in complex with the LCMV-derived GP392-401 peptide | 分子名称: | Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ... | 著者 | Buratto, J, Badia-Martinez, D, Norstrom, M, Sandalova, T, Achour, A. | 登録日 | 2016-05-12 | 公開日 | 2017-05-24 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of H-2Db in complex with the LCMV-derived peptides GP92 and GP392 explain pleiotropic effects of glycosylation on antigen presentation and immunogenicity. PLoS ONE, 12, 2017
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2BYZ
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![BU of 2byz by Molmil](/molmil-images/mine/2byz) | |
5K0W
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![BU of 5k0w by Molmil](/molmil-images/mine/5k0w) | Crystal structure of the metallo-beta-lactamase GOB-18 from Elizabethkingia meningoseptica | 分子名称: | CHLORIDE ION, Class B carbapenemase GOB-18, GLYCEROL, ... | 著者 | Buschiazzo, A, Larrieux, N, Vila, A.J, Lisa, M.N, Moran-Barrio, J. | 登録日 | 2016-05-17 | 公開日 | 2016-08-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Crystal Structure of the Metallo-beta-Lactamase GOB in the Periplasmic Dizinc Form Reveals an Unusual Metal Site. Antimicrob.Agents Chemother., 60, 2016
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4R0X
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![BU of 4r0x by Molmil](/molmil-images/mine/4r0x) | Allosteric coupling of conformational transitions in the FK1 domain of FKBP51 near the site of steroid receptor interaction | 分子名称: | Peptidyl-prolyl cis-trans isomerase FKBP5 | 著者 | LeMaster, D.M, Mustafi, S.M, Brecher, M, Zhang, J, Heroux, A, Li, H.M, Hernandez, G. | 登録日 | 2014-08-02 | 公開日 | 2015-05-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Coupling of Conformational Transitions in the N-terminal Domain of the 51-kDa FK506-binding Protein (FKBP51) Near Its Site of Interaction with the Steroid Receptor Proteins. J.Biol.Chem., 290, 2015
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7P00
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![BU of 7p00 by Molmil](/molmil-images/mine/7p00) | Human Neurokinin 1 receptor (NK1R) substance P Gq chimera (mGsqi) complex | 分子名称: | Antibody fragment scFv16, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Thom, C, Ehrenmann, J, Vacca, S, Waltenspuhl, Y, Schoppe, J, Medalia, O, Pluckthun, A. | 登録日 | 2021-06-29 | 公開日 | 2021-12-15 | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | 主引用文献 | Structures of neurokinin 1 receptor in complex with G q and G s proteins reveal substance P binding mode and unique activation features. Sci Adv, 7, 2021
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4R3F
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![BU of 4r3f by Molmil](/molmil-images/mine/4r3f) | Structure of the spliceosomal peptidyl-prolyl cis-trans isomerase Cwc27 from Chaetomium thermophilum | 分子名称: | 1,2-ETHANEDIOL, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ACETATE ION, ... | 著者 | Ulrich, A, Wahl, M.C. | 登録日 | 2014-08-15 | 公開日 | 2014-11-19 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Structure and evolution of the spliceosomal peptidyl-prolyl cis-trans isomerase Cwc27. Acta Crystallogr.,Sect.D, 70, 2014
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7P02
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![BU of 7p02 by Molmil](/molmil-images/mine/7p02) | Human Neurokinin 1 receptor (NK1R) substance P Gs complex | 分子名称: | Antibody fragment scFv16, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Thom, C, Ehrenmann, J, Vacca, S, Waltenspuhl, Y, Schoppe, J, Medalia, O, Pluckthun, A. | 登録日 | 2021-06-29 | 公開日 | 2021-12-15 | 実験手法 | ELECTRON MICROSCOPY (2.87 Å) | 主引用文献 | Structures of neurokinin 1 receptor in complex with G q and G s proteins reveal substance P binding mode and unique activation features. Sci Adv, 7, 2021
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7OU4
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![BU of 7ou4 by Molmil](/molmil-images/mine/7ou4) | The structure of MutS bound to one molecule of ATP and one molecule of ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA mismatch repair protein MutS, ... | 著者 | Lamers, M.H, Borsellini, A, Friedhoff, P, Kunetsky, V. | 登録日 | 2021-06-11 | 公開日 | 2022-01-12 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryogenic electron microscopy structures reveal how ATP and DNA binding in MutS coordinates sequential steps of DNA mismatch repair. Nat.Struct.Mol.Biol., 29, 2022
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7OTO
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![BU of 7oto by Molmil](/molmil-images/mine/7oto) | The structure of MutS bound to two molecules of AMPPNP | 分子名称: | DNA mismatch repair protein MutS, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Lamers, M.H, Borsellini, A, Friedhoff, P, Kunetsky, V. | 登録日 | 2021-06-10 | 公開日 | 2022-01-12 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryogenic electron microscopy structures reveal how ATP and DNA binding in MutS coordinates sequential steps of DNA mismatch repair. Nat.Struct.Mol.Biol., 29, 2022
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4R5Z
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![BU of 4r5z by Molmil](/molmil-images/mine/4r5z) | Crystal structure of Rv3772 encoded aminotransferase | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... | 著者 | Nasir, N, Anant, A, Vyas, R, Biswal, B.K. | 登録日 | 2014-08-22 | 公開日 | 2015-08-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structures of Mycobacterium tuberculosis HspAT and ArAT reveal structural basis of their distinct substrate specificities Sci Rep, 6, 2016
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7OU0
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![BU of 7ou0 by Molmil](/molmil-images/mine/7ou0) | The structure of MutS bound to two molecules of ADP-Vanadate | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA mismatch repair protein MutS, MAGNESIUM ION, ... | 著者 | Lamers, M.H, Borsellini, A, Friedhoff, P, Kunetsky, V. | 登録日 | 2021-06-10 | 公開日 | 2022-01-12 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Cryogenic electron microscopy structures reveal how ATP and DNA binding in MutS coordinates sequential steps of DNA mismatch repair. Nat.Struct.Mol.Biol., 29, 2022
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5K1P
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![BU of 5k1p by Molmil](/molmil-images/mine/5k1p) | |
4R6H
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![BU of 4r6h by Molmil](/molmil-images/mine/4r6h) | Crystal structure of putative binding protein msme from bacillus subtilis subsp. subtilis str. 168, target efi-510764, an open conformation | 分子名称: | CHLORIDE ION, Solute binding protein MsmE | 著者 | Patskovsky, Y, Toro, R, Bhosle, R, Al obaidi, N, Chamala, S, Attonito, J.D, Scott glenn, A, Chowdhury, S, Lafleur, J, Siedel, R.D, Hillerich, B, Love, J, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2014-08-25 | 公開日 | 2014-09-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal Structure of Transporter Msme from Bacillus Subtilis, Target Efi-510764 To be Published
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7OU2
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![BU of 7ou2 by Molmil](/molmil-images/mine/7ou2) | The structure of MutS bound to two molecules of ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA mismatch repair protein MutS | 著者 | Lamers, M.H, Borsellini, A, Friedhoff, P, Kunetsky, V. | 登録日 | 2021-06-11 | 公開日 | 2022-01-12 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Cryogenic electron microscopy structures reveal how ATP and DNA binding in MutS coordinates sequential steps of DNA mismatch repair. Nat.Struct.Mol.Biol., 29, 2022
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5K26
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![BU of 5k26 by Molmil](/molmil-images/mine/5k26) | |