5K26

Structure of the SH3 domain of MLK3 bound to peptide generated from phage display

Summary for 5K26

• Entry DOI: 10.2210/pdb5k26/pdb
• Related: 5K28
• Descriptor: Mitogen-activated protein kinase kinase kinase 11,Chimera protein of MLK3-SH3 and MIP, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID (3 entities in total)
• Functional Keywords: mlk3, sh3, phage display, signalling protein, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 18917.62

Authors

Kall, S.K.,Lavie, A. (deposition date: 2016-05-18, release date: 2017-12-13, Last modification date: 2023-09-27)

• Primary citation: Kokoszka, M.E.,Kall, S.L.,Khosla, S.,McGinnis, J.E.,Lavie, A.,Kay, B.K.; Identification of two distinct peptide-binding pockets in the SH3 domain of human mixed-lineage kinase 3.; J. Biol. Chem., 293:13553-13565, 2018; PubMed: 29980598; DOI: 10.1074/jbc.RA117.000262

Experimental method

X-RAY DIFFRACTION (1.2 Å)