5K26

Structure of the SH3 domain of MLK3 bound to peptide generated from phage display

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Mitogen-activated protein kinase kinase kinase 11,Chimera protein of MLK3-SH3 and MIP	polymer	86	9361.2	2	UniProt (Q16584) Pfam (PF14604)	Homo sapiens (Human)	Mixed lineage kinase 3,Src-homology 3 domain-containing proline-rich kinase,Mixed lineage kinase 3,Src-homology 3 domain-containing proline-rich kinase
2	C (A)	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	1	Chemie (MES)
3	D, E (A, B)	water	water		18.0	123	Chemie (HOH)

Sequence modifications

A, B: 41 - 105 (UniProt: Q16584)

PDB	External Database	Details
His 39	-	expression tag
Met 40	-	expression tag

A, B: 106 - 124 (PDB: 5K26)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	18722.4
Non-Polymers*	Number of molecules	1
	Total formula weight	195.2
All*	Total formula weight	18917.6

*Water molecules are not included.