8GVL
 
 | | PTPN21 FERM | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Tyrosine-protein phosphatase non-receptor type 21 | | 著者 | Chen, L, Zheng, Y.Y, Zhou, C. | | 登録日 | 2022-09-15 | | 公開日 | 2023-09-20 | | 最終更新日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural analysis of PTPN21 reveals a dominant-negative effect of the FERM domain on its phosphatase activity.
Sci Adv, 10, 2024
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8GVV
 | | PTPN21 PTP domain C1108S mutant | | 分子名称: | IODIDE ION, PHOSPHATE ION, Tyrosine-protein phosphatase non-receptor type 21 | | 著者 | Chen, L, Zheng, Y.Y, Zhou, C. | | 登録日 | 2022-09-15 | | 公開日 | 2023-09-20 | | 最終更新日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural analysis of PTPN21 reveals a dominant-negative effect of the FERM domain on its phosphatase activity.
Sci Adv, 10, 2024
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2LUY
 | | Solution structure of the tandem zinc finger domain of fission yeast Stc1 | | 分子名称: | Meiotic chromosome segregation protein P8B7.28c, ZINC ION | | 著者 | He, C, Shi, Y, Bayne, E, Wu, J. | | 登録日 | 2012-06-22 | | 公開日 | 2013-05-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural analysis of Stc1 provides insights into the coupling of RNAi and chromatin modification.
Proc.Natl.Acad.Sci.USA, 110, 2013
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6AWM
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6AZF
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8GBN
 | | Structure of Apo Human SIRT5 P114T Mutant | | 分子名称: | 1,2-ETHANEDIOL, NAD-dependent protein deacylase sirtuin-5, mitochondrial, ... | | 著者 | Petrunak, E.M, Stuckey, J.A. | | 登録日 | 2023-02-26 | | 公開日 | 2024-06-05 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Human SIRT5 variants with reduced stability and activity do not cause neuropathology in mice.
Iscience, 27, 2024
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8GBL
 | | Structure of Apo Human SIRT5 | | 分子名称: | NAD-dependent protein deacylase sirtuin-5, mitochondrial, ZINC ION | | 著者 | Petrunak, E.M, Stuckey, J.A. | | 登録日 | 2023-02-26 | | 公開日 | 2024-06-05 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Human SIRT5 variants with reduced stability and activity do not cause neuropathology in mice.
Iscience, 27, 2024
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8WQI
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8WQH
 | | cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 2) | | 分子名称: | Coiled-coil domain-containing protein 89, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | | 著者 | Chen, X, Zhang, K, Xu, C. | | 登録日 | 2023-10-11 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | | 主引用文献 | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
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8WQB
 | | Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 2) | | 分子名称: | Coiled-coil domain-containing protein 89, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | | 著者 | Chen, X, Zhang, K, Xu, C. | | 登録日 | 2023-10-11 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.37 Å) | | 主引用文献 | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
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8WQG
 | | cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 1) | | 分子名称: | Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ... | | 著者 | Chen, X, Zhang, K, Xu, C. | | 登録日 | 2023-10-11 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (4.09 Å) | | 主引用文献 | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
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8WQF
 | | cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CUX1 (conformation 2) | | 分子名称: | Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ... | | 著者 | Chen, X, Zhang, K, Xu, C. | | 登録日 | 2023-10-11 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | | 主引用文献 | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
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8WQC
 | | cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CDK5R1 | | 分子名称: | Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ... | | 著者 | Chen, X, Zhang, K, Xu, C. | | 登録日 | 2023-10-11 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | | 主引用文献 | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
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8WQE
 | | Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CUX1 (conformation 1) | | 分子名称: | Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ... | | 著者 | Chen, X, Zhang, K, Xu, C. | | 登録日 | 2023-10-11 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | | 主引用文献 | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
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8WQD
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8WQA
 | | Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 1) | | 分子名称: | Coiled-coil domain-containing protein 89, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... | | 著者 | Chen, X, Zhang, K, Xu, C. | | 登録日 | 2023-10-11 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | | 主引用文献 | Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
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5SWD
 | | Structure of the adenine riboswitch aptamer domain in an intermediate-bound state | | 分子名称: | ADENINE, MAGNESIUM ION, Vibrio vulnificus strain 93U204 chromosome II, ... | | 著者 | Stagno, J.R, Wang, Y.-X, Liu, Y, Bhandari, Y.R, Conrad, C.E, Nelson, G, Li, C, Wendel, D.R, White, T.A, Barty, A, Tuckey, R.A, Zatsepin, N.A, Grant, T.D, Fromme, P, Tan, K, Ji, X, Spence, J.C.H. | | 登録日 | 2016-08-08 | | 公開日 | 2016-11-23 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography.
Nature, 541, 2017
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6AWK
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6AZG
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6AXI
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3RER
 | | Crystal structure of E. coli Hfq in complex with AU6A RNA and ADP | | 分子名称: | 5'-R(*AP*UP*UP*UP*UP*UP*UP*A)-3', ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Wang, W.W, Wu, J.H, Shi, Y.Y. | | 登録日 | 2011-04-05 | | 公開日 | 2011-10-19 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Cooperation of Escherichia coli Hfq hexamers in DsrA binding.
Genes Dev., 25, 2011
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7E7E
 | | The co-crystal structure of ACE2 with Fab | | 分子名称: | Processed angiotensin-converting enzyme 2, ZINC ION, h11B11-Fab | | 著者 | Xiao, J.Y, Zhang, Y. | | 登録日 | 2021-02-26 | | 公開日 | 2021-07-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | A broadly neutralizing humanized ACE2-targeting antibody against SARS-CoV-2 variants.
Nat Commun, 12, 2021
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5SWE
 | | Ligand-bound structure of adenine riboswitch aptamer domain converted in crystal from its ligand-free state using ligand mixing serial femtosecond crystallography | | 分子名称: | ADENINE, Vibrio vulnificus strain 93U204 chromosome II, adenine riboswitch aptamer domain | | 著者 | Stagno, J.R, Wang, Y.-X, Liu, Y, Bhandari, Y.R, Conrad, C.E, Nelson, G, Li, C, Wendel, D.R, White, T.A, Barty, A, Tuckey, R.A, Zatsepin, N.A, Grant, T.D, Fromme, P, Tan, K, Ji, X, Spence, J.C.H. | | 登録日 | 2016-08-08 | | 公開日 | 2016-11-23 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography.
Nature, 541, 2017
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6AXJ
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6BHW
 | | B. subtilis SsbA | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Single-stranded DNA-binding protein A | | 著者 | Dubiel, K.D, Myers, A.R, Satyshur, K.A, Keck, J.L. | | 登録日 | 2017-10-31 | | 公開日 | 2018-12-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.208 Å) | | 主引用文献 | Structural Mechanisms of Cooperative DNA Binding by Bacterial Single-Stranded DNA-Binding Proteins.
J. Mol. Biol., 431, 2019
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