7E7E

The co-crystal structure of ACE2 with Fab

Summary for 7E7E

Entry DOI	10.2210/pdb7e7e/pdb
Descriptor	Processed angiotensin-converting enzyme 2, h11B11-Fab, ZINC ION, ... (4 entities in total)
Functional Keywords	ace2 fab, antiviral protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	6
Total formula weight	237932.69
Authors	Xiao, J.Y.,Zhang, Y. (deposition date: 2021-02-26, release date: 2021-07-14, Last modification date: 2023-11-29)
Primary citation	Du, Y.,Shi, R.,Zhang, Y.,Duan, X.,Li, L.,Zhang, J.,Wang, F.,Zhang, R.,Shen, H.,Wang, Y.,Wu, Z.,Peng, Q.,Pan, T.,Sun, W.,Huang, W.,Feng, Y.,Feng, H.,Xiao, J.,Tan, W.,Wang, Y.,Wang, C.,Yan, J. A broadly neutralizing humanized ACE2-targeting antibody against SARS-CoV-2 variants. Nat Commun, 12:5000-5000, 2021 Cited by PubMed: 34404805 DOI: 10.1038/s41467-021-25331-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.8 Å)

Structure validation