7L5K
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![BU of 7l5k by Molmil](/molmil-images/mine/7l5k) | Crystal structure of the DiB-RM protein | 分子名称: | DODECYL-BETA-D-MALTOSIDE, ISOPROPYL ALCOHOL, Lipocalin family protein, ... | 著者 | Bozhanova, N.G, Harp, J.M, Meiler, J. | 登録日 | 2020-12-22 | 公開日 | 2021-10-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Computational redesign of a fluorogen activating protein with Rosetta. Plos Comput.Biol., 17, 2021
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6MEY
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![BU of 6mey by Molmil](/molmil-images/mine/6mey) | Crystal structure of KPC-2 with compound 9 | 分子名称: | (2R)-2-phenyl-2-(phenylamino)-N-(1H-tetrazol-5-yl)acetamide, ACETATE ION, Carbapenem-hydrolyzing beta-lactamase KPC | 著者 | Akhtar, A, Chen, Y. | 登録日 | 2018-09-07 | 公開日 | 2019-04-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Active-Site Druggability of Carbapenemases and Broad-Spectrum Inhibitor Discovery. Acs Infect Dis., 5, 2019
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5T01
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![BU of 5t01 by Molmil](/molmil-images/mine/5t01) | Human c-Jun DNA binding domain homodimer in complex with methylated DNA | 分子名称: | DNA (5'-D(*AP*AP*TP*GP*GP*AP*(5CM)P*GP*AP*GP*TP*CP*AP*TP*AP*GP*GP*AP*G)-3'), DNA (5'-D(P*CP*TP*CP*CP*TP*AP*TP*GP*AP*CP*TP*CP*GP*TP*CP*CP*AP*T)-3'), Transcription factor AP-1 | 著者 | Hong, S, Horton, J.R, Cheng, X. | 登録日 | 2016-08-15 | 公開日 | 2017-03-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Methyl-dependent and spatial-specific DNA recognition by the orthologous transcription factors human AP-1 and Epstein-Barr virus Zta. Nucleic Acids Res., 45, 2017
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7XQ4
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![BU of 7xq4 by Molmil](/molmil-images/mine/7xq4) | Drimenyl diphosphate synthase from Streptomyces showdoensis (apo) | 分子名称: | SQHop_cyclase_C domain-containing protein | 著者 | Pan, X.M, Du, W.Y, Yang, Q, Zhang, B, Dong, L.B. | 登録日 | 2022-05-06 | 公開日 | 2023-03-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Discovery, Structure, and Mechanism of a Class II Sesquiterpene Cyclase. J.Am.Chem.Soc., 144, 2022
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5X4S
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![BU of 5x4s by Molmil](/molmil-images/mine/5x4s) | Structure of the N-terminal domain (NTD)of SARS-CoV spike protein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Yuan, Y, Zhang, Y, Qi, J, Shi, Y, Gao, G.F. | 登録日 | 2017-02-14 | 公開日 | 2017-05-03 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains Nat Commun, 8, 2017
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6MIA
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![BU of 6mia by Molmil](/molmil-images/mine/6mia) | Crystal structure of CTX-M-14 with compound 6 | 分子名称: | 3-(1H-tetrazol-5-ylmethyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one, Beta-lactamase | 著者 | Akhtar, A, Chen, Y. | 登録日 | 2018-09-19 | 公開日 | 2019-04-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.399 Å) | 主引用文献 | Active-Site Druggability of Carbapenemases and Broad-Spectrum Inhibitor Discovery. Acs Infect Dis., 5, 2019
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5ZYA
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![BU of 5zya by Molmil](/molmil-images/mine/5zya) | SF3b spliceosomal complex bound to E7107 | 分子名称: | PHD finger-like domain-containing protein 5A, POTASSIUM ION, Splicing factor 3B subunit 1, ... | 著者 | Finci, L.I, Larsen, N.A. | 登録日 | 2018-05-23 | 公開日 | 2018-06-20 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.95 Å) | 主引用文献 | The cryo-EM structure of the SF3b spliceosome complex bound to a splicing modulator reveals a pre-mRNA substrate competitive mechanism of action Genes Dev., 32, 2018
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6MD8
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![BU of 6md8 by Molmil](/molmil-images/mine/6md8) | Crystal structure of CTX-M-14 with compound 3 | 分子名称: | 1-(2,4-dichlorophenyl)-4-(1H-tetrazol-5-yl)-1H-pyrazol-5-amine, Beta-lactamase CTX-M-14, DIMETHYL SULFOXIDE | 著者 | Akhtar, A, Chen, Y. | 登録日 | 2018-09-04 | 公開日 | 2019-04-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Active-Site Druggability of Carbapenemases and Broad-Spectrum Inhibitor Discovery. Acs Infect Dis., 5, 2019
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6ACE
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![BU of 6ace by Molmil](/molmil-images/mine/6ace) | |
8FIV
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![BU of 8fiv by Molmil](/molmil-images/mine/8fiv) | |
8FIW
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![BU of 8fiw by Molmil](/molmil-images/mine/8fiw) | Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor Jun10221 | 分子名称: | 3C-like proteinase nsp5, N-([1,1'-biphenyl]-4-yl)-N-[(1R)-2-oxo-2-{[(1S)-1-phenylethyl]amino}-1-(pyridin-3-yl)ethyl]prop-2-enamide, N-([1,1'-biphenyl]-4-yl)-N-[(1S)-2-oxo-2-{[(1S)-1-phenylethyl]amino}-1-(pyridin-3-yl)ethyl]prop-2-enamide | 著者 | Sacco, M, Wang, J, Chen, Y. | 登録日 | 2022-12-16 | 公開日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | 主引用文献 | Exploring diverse reactive warheads for the design of SARS-CoV-2 main protease inhibitors. Eur.J.Med.Chem., 259, 2023
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8SBD
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![BU of 8sbd by Molmil](/molmil-images/mine/8sbd) | Cryo-EM structure of insulin amyloid-like fibril that is composed of two antiparallel protofilaments | 分子名称: | Insulin A chain, Insulin B chain | 著者 | Wang, L.W, Hall, C, Uchikawa, E, Chen, D.L, Choi, E, Zhang, X.W, Bai, X.C. | 登録日 | 2023-04-03 | 公開日 | 2023-08-30 | 最終更新日 | 2023-09-27 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis of insulin fibrillation. Sci Adv, 9, 2023
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7X4I
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![BU of 7x4i by Molmil](/molmil-images/mine/7x4i) | |
6MDU
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![BU of 6mdu by Molmil](/molmil-images/mine/6mdu) | Crystal structure of NDM-1 with compound 7 | 分子名称: | 1,5-diphenyl-N-(1H-tetrazol-5-yl)-1H-pyrazole-3-carboxamide, GLYCEROL, Metallo-beta-lactamase type 2, ... | 著者 | Akhtar, A, Chen, Y. | 登録日 | 2018-09-05 | 公開日 | 2019-04-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Active-Site Druggability of Carbapenemases and Broad-Spectrum Inhibitor Discovery. Acs Infect Dis., 5, 2019
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5V5F
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![BU of 5v5f by Molmil](/molmil-images/mine/5v5f) | Crystal structure of RICE1 (PNT2) | 分子名称: | At3g11770 | 著者 | Li, P. | 登録日 | 2017-03-14 | 公開日 | 2017-09-13 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.945 Å) | 主引用文献 | RISC-interacting clearing 3'- 5' exoribonucleases (RICEs) degrade uridylated cleavage fragments to maintain functional RISC in Arabidopsis thaliana. Elife, 6, 2017
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7XQZ
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![BU of 7xqz by Molmil](/molmil-images/mine/7xqz) | Drimenyl diphosphate synthase D303A from Streptomyces showdoensis in complex with 2-fluorofarnesyl diphosphate (2F-FPP) and Mg2+ | 分子名称: | (2Z,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, MAGNESIUM ION, SQHop_cyclase_C domain-containing protein | 著者 | Pan, X.M, Du, W.Y, Yang, Q, Zhang, B, Dong, L.B. | 登録日 | 2022-05-09 | 公開日 | 2023-03-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery, Structure, and Mechanism of a Class II Sesquiterpene Cyclase. J.Am.Chem.Soc., 144, 2022
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7XR7
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![BU of 7xr7 by Molmil](/molmil-images/mine/7xr7) | Drimenyl diphosphate synthase D303E from Streptomyces showdoensis in complex with farnesyl diphosphate (FPP) and Mg2+ | 分子名称: | FARNESYL DIPHOSPHATE, MAGNESIUM ION, SQHop_cyclase_C domain-containing protein | 著者 | Pan, X.M, Du, W.Y, Yang, Q, Zhang, B, Dong, L.B. | 登録日 | 2022-05-09 | 公開日 | 2023-03-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Discovery, Structure, and Mechanism of a Class II Sesquiterpene Cyclase. J.Am.Chem.Soc., 144, 2022
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7XRU
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![BU of 7xru by Molmil](/molmil-images/mine/7xru) | Drimenyl diphosphate synthase D303E from Streptomyces showdoensis in complex with 2-fluorofarnesyl diphosphate (2F-FPP) and Mg2+ | 分子名称: | (2E,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, MAGNESIUM ION, SQHop_cyclase_C domain-containing protein | 著者 | Pan, X.M, Du, W.Y, Yang, Q, Zhang, B, Dong, L.B. | 登録日 | 2022-05-11 | 公開日 | 2023-03-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Discovery, Structure, and Mechanism of a Class II Sesquiterpene Cyclase. J.Am.Chem.Soc., 144, 2022
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7XRA
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![BU of 7xra by Molmil](/molmil-images/mine/7xra) | Drimenyl diphosphate synthase D303A from Streptomyces showdoensis in complex with farnesyl diphosphate (FPP) and Mg2+ | 分子名称: | FARNESYL DIPHOSPHATE, MAGNESIUM ION, SQHop_cyclase_C domain-containing protein | 著者 | Pan, X.M, Du, W.Y, Yang, Q, Zhang, B, Dong, L.B. | 登録日 | 2022-05-09 | 公開日 | 2023-03-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Discovery, Structure, and Mechanism of a Class II Sesquiterpene Cyclase. J.Am.Chem.Soc., 144, 2022
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2LI6
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![BU of 2li6 by Molmil](/molmil-images/mine/2li6) | |
5TJ8
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![BU of 5tj8 by Molmil](/molmil-images/mine/5tj8) | |
4M5E
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![BU of 4m5e by Molmil](/molmil-images/mine/4m5e) | Tse3 structure | 分子名称: | CADMIUM ION, CALCIUM ION, GLYCEROL, ... | 著者 | Qian, Y. | 登録日 | 2013-08-08 | 公開日 | 2014-04-23 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Structural insights into the T6SS effector protein Tse3 and the Tse3-Tsi3 complex from Pseudomonas aeruginosa reveal a calcium-dependent membrane-binding mechanism Mol.Microbiol., 92, 2014
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6MNP
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![BU of 6mnp by Molmil](/molmil-images/mine/6mnp) | Crystal structure of KPC-2 with compound 6 | 分子名称: | 3-(1H-tetrazol-5-ylmethyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one, Carbapenem-hydrolyzing beta-lactamase KPC, GLYCEROL | 著者 | Akhtar, A, Chen, Y. | 登録日 | 2018-10-02 | 公開日 | 2019-04-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | 主引用文献 | Active-Site Druggability of Carbapenemases and Broad-Spectrum Inhibitor Discovery. Acs Infect Dis., 5, 2019
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6MLL
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![BU of 6mll by Molmil](/molmil-images/mine/6mll) | Crystal structure of KPC-2 with compound 7 | 分子名称: | 1,5-diphenyl-N-(1H-tetrazol-5-yl)-1H-pyrazole-3-carboxamide, Carbapenem-hydrolyzing beta-lactamase KPC, GLYCEROL | 著者 | Akhtar, A, Chen, Y. | 登録日 | 2018-09-27 | 公開日 | 2019-04-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Active-Site Druggability of Carbapenemases and Broad-Spectrum Inhibitor Discovery. Acs Infect Dis., 5, 2019
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5TJ7
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![BU of 5tj7 by Molmil](/molmil-images/mine/5tj7) | |