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6YWP
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BU of 6ywp by Molmil
Structure of apo-CutA
分子名称: CutA, MAGNESIUM ION
著者Malik, D, Kobylecki, K, Krawczyk, P, Poznanski, J, Jakielaszek, A, Napiorkowska, A, Dziembowski, A, Tomecki, R, Nowotny, M.
登録日2020-04-29
公開日2020-08-05
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structure and mechanism of CutA, RNA nucleotidyl transferase with an unusual preference for cytosine.
Nucleic Acids Res., 48, 2020
6ZIO
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BU of 6zio by Molmil
CRYSTAL STRUCTURE OF NRAS (C118S) IN COMPLEX WITH GDP
分子名称: GTPase NRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Kessler, D, Fischer, G, Boettcher, J.
登録日2020-06-26
公開日2020-08-19
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Drugging all RAS isoforms with one pocket.
Future Med Chem, 12, 2020
6YXY
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BU of 6yxy by Molmil
State B of the Trypanosoma brucei mitoribosomal large subunit assembly intermediate
分子名称: 12S ribosomal RNA, ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Jaskolowski, M, Ramrath, D.J.F, Bieri, P, Niemann, M, Mattei, S, Calderaro, S, Leibundgut, M.A, Horn, E.K, Boehringer, D, Schneider, A, Ban, N.
登録日2020-05-04
公開日2020-10-14
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural Insights into the Mechanism of Mitoribosomal Large Subunit Biogenesis.
Mol.Cell, 79, 2020
6ZKA
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BU of 6zka by Molmil
Membrane domain of open complex I during turnover
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, ...
著者Kampjut, D, Sazanov, L.A.
登録日2020-06-30
公開日2020-10-07
最終更新日2025-04-09
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献The coupling mechanism of mammalian respiratory complex I.
Science, 370, 2020
6YUP
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BU of 6yup by Molmil
Heterotetrameric structure of the rBAT-b(0,+)AT1 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neutral and basic amino acid transport protein rBAT, ...
著者Wu, D, Safarian, S, Michel, H.
登録日2020-04-27
公開日2021-01-20
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis for amino acid exchange by a human heteromeric amino acid transporter.
Proc.Natl.Acad.Sci.USA, 117, 2020
6ZKP
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BU of 6zkp by Molmil
Native complex I, open1
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ADENOSINE MONOPHOSPHATE, ...
著者Kampjut, D, Sazanov, L.A.
登録日2020-06-30
公開日2020-10-07
最終更新日2025-04-09
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The coupling mechanism of mammalian respiratory complex I.
Science, 370, 2020
6ZLC
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BU of 6zlc by Molmil
Non-specific dsRNA recognition by wildtype H7N1 RNA-binding domain
分子名称: NITRATE ION, Non-structural protein 1, RNA (5'-R(*AP*GP*AP*CP*AP*GP*CP*AP*UP*UP*AP*UP*GP*CP*UP*GP*UP*CP*U)-3'), ...
著者Coste, F, Wacquiez, A, Marc, D, Castaing, B.
登録日2020-06-30
公開日2020-10-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1.
Viruses, 12, 2020
6YU5
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BU of 6yu5 by Molmil
Crystal structure of MhsT in complex with L-valine
分子名称: DODECYL-BETA-D-MALTOSIDE, SODIUM ION, Sodium-dependent transporter, ...
著者Focht, D, Neumann, C, Lyons, J, Eguskiza Bilbao, A, Blunck, R, Malinauskaite, L, Schwarz, I.O, Javitch, J.A, Quick, M, Nissen, P.
登録日2020-04-25
公開日2020-07-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A non-helical region in transmembrane helix 6 of hydrophobic amino acid transporter MhsT mediates substrate recognition.
Embo J., 40, 2021
6Z36
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BU of 6z36 by Molmil
Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2118
分子名称: 1,2-ETHANEDIOL, 4-methyl-3-(4-piperidin-4-ylphenyl)-5-(3,4,5-trimethoxyphenyl)pyridine, AMMONIUM ION, ...
著者Adamson, R.J, Williams, E.P, Smil, D, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N.
登録日2020-05-19
公開日2020-05-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2118
To Be Published
6Z3Q
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BU of 6z3q by Molmil
Structure of EV71 in complex with a protective antibody 38-1-10A Fab
分子名称: Heavy chain, Light chain, SPHINGOSINE, ...
著者Zhou, D, Fry, E.E, Ren, J, Stuart, D.I.
登録日2020-05-21
公開日2020-09-02
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural and functional analysis of protective antibodies targeting the threefold plateau of enterovirus 71.
Nat Commun, 11, 2020
6Z4D
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BU of 6z4d by Molmil
Crystal Structure of EGFR-T790M/V948R in Complex with Mavelertinib and EAI001
分子名称: (2R)-2-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)-2-phenyl-N-(1,3-thiazol-2-yl)acetamide, Epidermal growth factor receptor, N-[(3R,4R)-4-fluoro-1-{6-[(3-methoxy-1-methyl-1H-pyrazol-4-yl)amino]-9-methyl-9H-purin-2-yl}pyrrolidin-3-yl]propanamide, ...
著者Niggenaber, J, Mueller, M.P, Rauh, D.
登録日2020-05-25
公開日2020-11-11
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Complex Crystal Structures of EGFR with Third-Generation Kinase Inhibitors and Simultaneously Bound Allosteric Ligands.
Acs Med.Chem.Lett., 11, 2020
8DYA
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BU of 8dya by Molmil
Structure of the SARS-CoV-2 spike glycoprotein S2 subunit
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
登録日2022-08-03
公開日2022-11-30
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.67 Å)
主引用文献SARS-CoV-2 spike conformation determines plasma neutralizing activity elicited by a wide panel of human vaccines.
Sci Immunol, 7, 2022
6ZAW
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BU of 6zaw by Molmil
Damage-free NO-bound copper nitrite reductase from Bradyrhizobium sp. ORS 375 (two-domain) determined by serial femtosecond rotation crystallography
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, COPPER (II) ION, Copper-containing nitrite reductase, ...
著者Rose, S.L, Antonyuk, S.V, Sasaki, D, Yamashita, K, Hirata, K, Ueno, G, Ago, H, Eady, R.R, Tosha, T, Yamamoto, M, Hasnain, S.S.
登録日2020-06-05
公開日2021-01-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献An unprecedented insight into the catalytic mechanism of copper nitrite reductase from atomic-resolution and damage-free structures.
Sci Adv, 7, 2021
6ZAR
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BU of 6zar by Molmil
As-isolated copper nitrite reductase from Bradyrhizobium sp. ORS 375 (two-domain) at 1.1 A resolution (unrestrained, full matrix refinement by SHELX)
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, COPPER (II) ION, Copper-containing nitrite reductase, ...
著者Rose, S.L, Antonyuk, S.V, Sasaki, D, Yamashita, K, Hirata, K, Ueno, G, Ago, H, Eady, R.R, Tosha, T, Yamamoto, M, Hasnain, S.S.
登録日2020-06-05
公開日2021-01-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献An unprecedented insight into the catalytic mechanism of copper nitrite reductase from atomic-resolution and damage-free structures.
Sci Adv, 7, 2021
6ZKD
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BU of 6zkd by Molmil
Complex I during turnover, open1
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
著者Kampjut, D, Sazanov, L.A.
登録日2020-06-30
公開日2020-10-07
最終更新日2025-04-09
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献The coupling mechanism of mammalian respiratory complex I.
Science, 370, 2020
6Z8F
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BU of 6z8f by Molmil
Human Picobirnavirus D45-CP VLP
分子名称: Capsid protein precursor
著者Ortega-Esteban, A, Mata, C.P, Rodriguez-Espinosa, M.J, Luque, D, Irigoyen, N, Rodriguez, J.M, de Pablo, P.J, Caston, J.R.
登録日2020-06-02
公開日2020-09-16
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Cryo-electron Microscopy Structure, Assembly, and Mechanics Show Morphogenesis and Evolution of Human Picobirnavirus.
J.Virol., 94, 2020
6ZKT
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BU of 6zkt by Molmil
Deactive complex I, open2
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ADENOSINE MONOPHOSPHATE, ...
著者Kampjut, D, Sazanov, L.A.
登録日2020-06-30
公開日2020-10-07
最終更新日2025-04-09
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献The coupling mechanism of mammalian respiratory complex I.
Science, 370, 2020
6Z9M
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BU of 6z9m by Molmil
Pseudoatomic model of the pre-fusion conformation of glycoprotein B of Herpes simplex virus 1
分子名称: Envelope glycoprotein B
著者Vollmer, B, Prazak, V, Vasishtan, D, Jefferys, E.E, Hernandez-Duran, A, Vallbracht, M, Klupp, B, Mettenleiter, T.C, Backovic, M, Rey, F.A, Topf, M, Gruenewald, K.
登録日2020-06-04
公開日2020-10-07
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (9.1 Å)
主引用文献The prefusion structure of herpes simplex virus glycoprotein B.
Sci Adv, 6, 2020
6ZAX
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BU of 6zax by Molmil
Nitrite-bound copper nitrite reductase from Bradyrhizobium sp. ORS 375 (two-domain) at low dose (0.5 MGy)
分子名称: COPPER (II) ION, Copper-containing nitrite reductase, GLYCEROL, ...
著者Rose, S.L, Antonyuk, S.V, Sasaki, D, Yamashita, K, Hirata, K, Ueno, G, Ago, H, Eady, R.R, Tosha, T, Yamamoto, M, Hasnain, S.S.
登録日2020-06-05
公開日2021-01-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献An unprecedented insight into the catalytic mechanism of copper nitrite reductase from atomic-resolution and damage-free structures.
Sci Adv, 7, 2021
6ZKG
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BU of 6zkg by Molmil
Complex I with NADH, closed
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
著者Kampjut, D, Sazanov, L.A.
登録日2020-06-30
公開日2020-10-07
最終更新日2025-04-09
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献The coupling mechanism of mammalian respiratory complex I.
Science, 370, 2020
6ZKF
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BU of 6zkf by Molmil
Complex I during turnover, open3
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
著者Kampjut, D, Sazanov, L.A.
登録日2020-06-30
公開日2020-10-14
最終更新日2025-04-09
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献The coupling mechanism of mammalian respiratory complex I.
Science, 370, 2020
6ZKU
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BU of 6zku by Molmil
Deactive complex I, open3
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ADENOSINE MONOPHOSPHATE, ...
著者Kampjut, D, Sazanov, L.A.
登録日2020-06-30
公開日2020-10-07
最終更新日2025-04-09
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献The coupling mechanism of mammalian respiratory complex I.
Science, 370, 2020
6YU7
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BU of 6yu7 by Molmil
Crystal structure of MhsT in complex with L-tyrosine
分子名称: DODECYL-BETA-D-MALTOSIDE, SODIUM ION, Sodium-dependent transporter, ...
著者Focht, D, Neumann, C, Lyons, J, Eguskiza Bilbao, A, Blunck, R, Malinauskaite, L, Schwarz, I.O, Javitch, J.A, Quick, M, Nissen, P.
登録日2020-04-25
公開日2020-07-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A non-helical region in transmembrane helix 6 of hydrophobic amino acid transporter MhsT mediates substrate recognition.
Embo J., 40, 2021
6YYH
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BU of 6yyh by Molmil
Crystal structure of beta-D-xylosidase from Dictyoglomus thermophilum in ligand-free form
分子名称: 1,2-ETHANEDIOL, Beta-xylosidase, CITRIC ACID, ...
著者Lafite, P, Daniellou, R, Bretagne, D.
登録日2020-05-05
公開日2020-12-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Crystal structure of Dictyoglomus thermophilum beta-d-xylosidase DtXyl unravels the structural determinants for efficient notoginsenoside R1 hydrolysis.
Biochimie, 181, 2020
6YZ2
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BU of 6yz2 by Molmil
Full length Open-form Sodium Channel NavMs F208L
分子名称: DODECAETHYLENE GLYCOL, HEGA-10, Ion transport protein, ...
著者Sula, A, Sait, L.G, Hollingworth, D, Wallace, B.A.
登録日2020-05-06
公開日2020-11-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Cannabidiol interactions with voltage-gated sodium channels.
Elife, 9, 2020

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件を2025-07-09に公開中

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