5ZH3
 
 | | CRYSTAL STRUCTURE OF PfKRS WITH INHIBITOR CLADO-6 | | 分子名称: | (3S)-6,8-dihydroxy-3-{[(2R,6R)-6-methyloxan-2-yl]methyl}-3,4-dihydro-1H-2-benzopyran-1-one, LYSINE, Lysine-tRNA ligase | | 著者 | Babbar, P, Malhotra, N, Sharma, M, Harlos, K, Reddy, D.S, Manickam, Y, Sharma, A. | | 登録日 | 2018-03-11 | | 公開日 | 2018-06-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | | 主引用文献 | Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite
J. Med. Chem., 61, 2018
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1E5S
 | | Proline 3-hydroxylase (type II) - Iron form | | 分子名称: | FE (II) ION, PROLINE OXIDASE, SULFATE ION | | 著者 | Clifton, I.J, Hsueh, L.C, Baldwin, J.E, Schofield, C.J, Harlos, K. | | 登録日 | 2000-07-28 | | 公開日 | 2001-07-26 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of proline 3-hydroxylase. Evolution of the family of 2-oxoglutarate dependent oxygenases.
Eur.J.Biochem., 268, 2001
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5ZH5
 | | CRYSTAL STRUCTURE OF PfKRS WITH INHIBITOR CLADO-2 | | 分子名称: | (3S)-6,8-dihydroxy-3-{[(2R,6S)-6-methyloxan-2-yl]methyl}-3,4-dihydro-1H-2-benzopyran-1-one, CHLORIDE ION, LYSINE, ... | | 著者 | Babbar, P, Malhotra, N, Sharma, M, Harlos, K, Reddy, D.S, Manickam, Y, Sharma, A. | | 登録日 | 2018-03-11 | | 公開日 | 2018-06-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.08 Å) | | 主引用文献 | Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite
J. Med. Chem., 61, 2018
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5ZH2
 | | CRYSTAL STRUCTURE OF PfKRS WITH INHIBITOR CLADO-5 | | 分子名称: | (3R)-6,8-dihydroxy-3-{[(2R,6R)-6-methyloxan-2-yl]methyl}-3,4-dihydro-1H-2-benzopyran-1-one, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, ... | | 著者 | Babbar, P, Malhotra, N, Sharma, M, Harlos, K, Reddy, D.S, Manickam, Y, Sharma, A. | | 登録日 | 2018-03-11 | | 公開日 | 2018-06-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | | 主引用文献 | Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite
J. Med. Chem., 61, 2018
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5ZKE
 | | Crystal Structure of N-terminal Domain of Plasmodium vivax p43 in space group P212121 | | 分子名称: | Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein p43 | | 著者 | Gupta, S, Sharma, M, Harlos, K, Manickam, Y, Sharma, A. | | 登録日 | 2018-03-23 | | 公開日 | 2019-04-24 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.492 Å) | | 主引用文献 | Crystal structures of the two domains that constitute the Plasmodium vivax p43 protein.
Acta Crystallogr D Struct Biol, 76, 2020
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5ZKF
 | | Crystal Structure of N-terminal Domain of Plasmodium vivax p43 in space group P21 | | 分子名称: | Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein p43 | | 著者 | Gupta, S, Sharma, M, Harlos, K, Manickam, Y, Sharma, A. | | 登録日 | 2018-03-23 | | 公開日 | 2019-04-24 | | 最終更新日 | 2020-03-11 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Crystal structures of the two domains that constitute the Plasmodium vivax p43 protein.
Acta Crystallogr D Struct Biol, 76, 2020
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2UVD
 | | The crystal structure of a 3-oxoacyl-(acyl carrier protein) reductase from Bacillus anthracis (BA3989) | | 分子名称: | 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE | | 著者 | Zaccai, N.R, Carter, L.G, Berrow, N.S, Sainsbury, S, Nettleship, J.E, Walter, T.S, Harlos, K, Owens, R.J, Wilson, K.S, Stuart, D.I, Esnouf, R.M, Oxford Protein Production Facility (OPPF), Structural Proteomics in Europe (SPINE) | | 登録日 | 2007-03-09 | | 公開日 | 2007-04-17 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structure of a 3-Oxoacyl-(Acylcarrier Protein) Reductase (Ba3989) from Bacillus Anthracis at 2.4-A Resolution.
Proteins: Struct., Funct., Bioinf., 70, 2008
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1DRY
 | | CRYSTAL STRUCTURE OF CLAVAMINATE SYNTHASE IN COMPLEX WITH FE(II), 2-OXOGLUTARATE AND N-ALPHA-L-ACETYL ARGININE | | 分子名称: | 2-OXOGLUTARIC ACID, CLAVAMINATE SYNTHASE 1, FE (II) ION, ... | | 著者 | Zhang, Z.H, Ren, J, Stammers, D.K, Baldwin, J.E, Harlos, K, Schofield, C.J. | | 登録日 | 2000-01-06 | | 公開日 | 2000-07-06 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structural origins of the selectivity of the trifunctional oxygenase clavaminic acid synthase.
Nat.Struct.Biol., 7, 2000
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1DS1
 | | CRYSTAL STRUCTURE OF CLAVAMINATE SYNTHASE IN COMPLEX WITH FE(II) AND 2-OXOGLUTARATE | | 分子名称: | 2-OXOGLUTARIC ACID, CLAVAMINATE SYNTHASE 1, FE (II) ION, ... | | 著者 | Zhang, Z.H, Ren, J, Stammers, D.K, Baldwin, J.E, Harlos, K, Schofield, C.J. | | 登録日 | 2000-01-06 | | 公開日 | 2000-07-06 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | | 主引用文献 | Structural origins of the selectivity of the trifunctional oxygenase clavaminic acid synthase.
Nat.Struct.Biol., 7, 2000
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1DRT
 | | CRYSTAL STRUCTURE OF CLAVAMINATE SYNTHASE IN COMPLEX WITH FE(II), 2-OXOGLUTARATE AND PROCLAVAMINIC ACID | | 分子名称: | 2-OXOGLUTARIC ACID, 5-AMINO-3-HYDROXY-2-(2-OXO-AZETIDIN-1-YL)-PENTANOIC ACID, CLAVAMINATE SYNTHASE 1, ... | | 著者 | Zhang, Z.H, Ren, J, Stammers, D.K, Baldwin, J.E, Harlos, K, Schofield, C.J. | | 登録日 | 2000-01-06 | | 公開日 | 2000-07-06 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural origins of the selectivity of the trifunctional oxygenase clavaminic acid synthase.
Nat.Struct.Biol., 7, 2000
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4BKA
 | | crystal structure of the human EphA4 ectodomain in complex with human ephrin A5 | | 分子名称: | EPHRIN TYPE-A RECEPTOR 4, EPHRIN-A5 | | 著者 | Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y. | | 登録日 | 2013-04-23 | | 公開日 | 2013-07-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (5.3 Å) | | 主引用文献 | Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
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4BK4
 | | crystal structure of the human EphA4 ectodomain | | 分子名称: | EPHRIN TYPE-A RECEPTOR 4 | | 著者 | Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y. | | 登録日 | 2013-04-22 | | 公開日 | 2013-07-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | | 主引用文献 | Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
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2UV3
 | | Structure of the signal-regulatory protein (SIRP) alpha domain that binds CD47. | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SULFATE ION, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1 | | 著者 | Hatherley, D, Harlos, K, Dunlop, D.C, Stuart, D.I, Barclay, A.N. | | 登録日 | 2007-03-08 | | 公開日 | 2007-03-27 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The Structure of the Macrophage Signal Regulatory Protein Alpha (Sirpalpha) Inhibitory Receptor Reveals a Binding Face Reminiscent of that Used by T Cell Receptors.
J.Biol.Chem., 282, 2007
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4CSA
 | | Crystal structure of the asymmetric human metapneumovirus M2-1 tetramer bound to a DNA 4-mer | | 分子名称: | 5'-D(*AP*GP*TP*TP*AP)-3', GLYCEROL, M2-1, ... | | 著者 | Leyrat, C, Renner, M, Harlos, K, Grimes, J.M. | | 登録日 | 2014-03-05 | | 公開日 | 2014-05-28 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Drastic Changes in Conformational Dynamics of the Antiterminator M2-1 Regulate Transcription Efficiency in Pneumovirinae.
Elife, 3, 2014
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2VSC
 | | Structure of the immunoglobulin-superfamily ectodomain of human CD47 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, LEUKOCYTE SURFACE ANTIGEN CD47, MAGNESIUM ION | | 著者 | Hatherley, D, Graham, S.C, Turner, J, Harlos, K, Stuart, D.I, Barclay, A.N. | | 登録日 | 2008-04-22 | | 公開日 | 2008-08-12 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Paired Receptor Specificity Explained by Structures of Signal Regulatory Proteins Alone and Complexed with Cd47.
Mol.Cell, 31, 2008
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2WFR
 | | Crystal structure of the N-terminal signalling domain of human Dhh with calcium | | 分子名称: | CALCIUM ION, DESERT HEDGEHOG PROTEIN N-PRODUCT, SULFATE ION, ... | | 著者 | Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C. | | 登録日 | 2009-04-14 | | 公開日 | 2009-06-30 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
Nat.Struct.Mol.Biol., 16, 2009
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2WAH
 | | Crystal Structure of an IgG1 Fc Glycoform (Man9GlcNAc2) | | 分子名称: | IG GAMMA-1 CHAIN C REGION, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Crispin, M, Bowden, T.A, Coles, C.H, Harlos, K, Aricescu, A.R, Harvey, D.J, Stuart, D.I, Jones, E.Y. | | 登録日 | 2009-02-06 | | 公開日 | 2009-03-10 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Carbohydrate and Domain Architecture of an Immature Antibody Glycoform Exhibiting Enhanced Effector Functions
J.Mol.Biol., 387, 2009
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2W8X
 | | Structure of the tick ion-channel modulator Ra-KLP | | 分子名称: | ACETATE ION, GLYCEROL, IMIDAZOLE, ... | | 著者 | Paesen, G.C, Siebold, C, Dallas, M, Peers, C, Harlos, K, Nuttall, P.A, Nunn, M.A, Stuart, D.I, Esnouf, R.M. | | 登録日 | 2009-01-20 | | 公開日 | 2009-05-05 | | 最終更新日 | 2017-06-28 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | An Ion-Channel Modulator from the Saliva of the Brown Ear Tick Has a Highly Modified Kunitz/Bpti Structure.
J.Mol.Biol., 389, 2009
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3ZMN
 | | VP17, a capsid protein of bacteriophage P23-77 | | 分子名称: | VP17 | | 著者 | Rissanen, I, Grimes, J.M, Pawlowski, A, Mantynen, S, Harlos, K, Bamford, J.K.H, Stuart, D.I. | | 登録日 | 2013-02-11 | | 公開日 | 2013-05-15 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Bacteriophage P23-77 Capsid Protein Structures Reveal the Archetype of an Ancient Branch from a Major Virus Lineage.
Structure, 21, 2013
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4BXT
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2WG3
 | | Crystal structure of the complex between human hedgehog-interacting protein HIP and desert hedgehog without calcium | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DESERT HEDGEHOG PROTEIN N-PRODUCT, ... | | 著者 | Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C. | | 登録日 | 2009-04-15 | | 公開日 | 2009-06-30 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
Nat.Struct.Mol.Biol., 16, 2009
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2WFT
 | | Crystal structure of the human HIP ectodomain | | 分子名称: | CHLORIDE ION, HEDGEHOG-INTERACTING PROTEIN, SODIUM ION | | 著者 | Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C. | | 登録日 | 2009-04-15 | | 公開日 | 2009-06-30 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
Nat.Struct.Mol.Biol., 16, 2009
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2WFQ
 | | Crystal structure of the N-terminal signalling domain of human Dhh without calcium | | 分子名称: | DESERT HEDGEHOG PROTEIN N-PRODUCT, SULFATE ION, ZINC ION | | 著者 | Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C. | | 登録日 | 2009-04-14 | | 公開日 | 2009-06-30 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
Nat.Struct.Mol.Biol., 16, 2009
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1E5R
 | | Proline 3-hydroxylase (type II) -apo form | | 分子名称: | PROLINE OXIDASE | | 著者 | Clifton, I.J, Hsueh, L.C, Baldwin, J.E, Schofield, C.J, Harlos, K. | | 登録日 | 2000-07-28 | | 公開日 | 2001-07-26 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of proline 3-hydroxylase. Evolution of the family of 2-oxoglutarate dependent oxygenases.
Eur.J.Biochem., 268, 2001
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2WFX
 | | Crystal structure of the complex between human hedgehog-interacting protein HIP and Sonic Hedgehog in the presence of calcium | | 分子名称: | CALCIUM ION, HEDGEHOG-INTERACTING PROTEIN, SODIUM ION, ... | | 著者 | Bishop, B, Aricescu, A.R, Harlos, K, O'Callaghan, C.A, Jones, E.Y, Siebold, C. | | 登録日 | 2009-04-15 | | 公開日 | 2009-06-30 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural Insights Into Hedgehog Ligand Sequestration by the Human Hedgehog-Interacting Protein Hip
Nat.Struct.Mol.Biol., 16, 2009
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