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6FNH
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BU of 6fnh by Molmil
Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with a pyrazolo[3,4-d]pyrimidine fragment of NVP-BHG712
分子名称: 1,2-ETHANEDIOL, 1-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-amine, Ephrin type-A receptor 2
著者Kudlinzki, D, Troester, A, Witt, K, Linhard, V.L, Gande, S.L, Saxena, K, Schwalbe, H.
登録日2018-02-04
公開日2018-08-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.379 Å)
主引用文献NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family.
ChemMedChem, 13, 2018
6FNG
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BU of 6fng by Molmil
Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with an isomer of NVP-BHG712
分子名称: 1,2-ETHANEDIOL, 4-methyl-3-[(2-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-yl)amino]-~{N}-[3-(trifluoromethyl)phenyl]benzamide, Ephrin type-A receptor 2
著者Kudlinzki, D, Troester, A, Witt, K, Linhard, V.L, Gande, S.L, Saxena, K, Schwalbe, H.
登録日2018-02-04
公開日2018-08-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.038 Å)
主引用文献NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family.
ChemMedChem, 13, 2018
6FNM
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BU of 6fnm by Molmil
Crystal Structure of Ephrin B4 (EphB4) Receptor Protein Kinase with Dasatinib
分子名称: Ephrin type-B receptor 4, N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE
著者Kudlinzki, D, Troester, A, Witt, K, Linhard, V.L, Saxena, K, Schwalbe, H.
登録日2018-02-04
公開日2018-08-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.157 Å)
主引用文献NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family.
ChemMedChem, 13, 2018
6FNJ
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BU of 6fnj by Molmil
Crystal Structure of Ephrin B4 (EphB4) Receptor Protein Kinase with an isomer of NVP-BHG712
分子名称: 1,2-ETHANEDIOL, 4-methyl-3-[(2-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-yl)amino]-~{N}-[3-(trifluoromethyl)phenyl]benzamide, Ephrin type-B receptor 4
著者Kudlinzki, D, Troester, A, Witt, K, Linhard, V.L, Saxena, K, Schwalbe, H.
登録日2018-02-04
公開日2018-08-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.239 Å)
主引用文献NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family.
ChemMedChem, 13, 2018
6FNF
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BU of 6fnf by Molmil
Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with NVP-BHG712
分子名称: 4-methyl-3-[(1-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-yl)amino]-~{N}-[3-(trifluoromethyl)phenyl]benzamide, Ephrin type-A receptor 2
著者Kudlinzki, D, Troester, A, Witt, K, Linhard, V.L, Gande, S.L, Saxena, K, Schwalbe, H.
登録日2018-02-04
公開日2018-08-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.556 Å)
主引用文献NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family.
ChemMedChem, 13, 2018
6FNK
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BU of 6fnk by Molmil
Crystal Structure of Ephrin B4 (EphB4) Receptor Protein Kinase with a pyrazolo[3,4-d]pyrimidine fragment of NVP-BHG712
分子名称: 1,2-ETHANEDIOL, 1-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-amine, Ephrin type-B receptor 4
著者Kudlinzki, D, Troester, A, Witt, K, Linhard, V.L, Saxena, K, Schwalbe, H.
登録日2018-02-04
公開日2018-08-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.049 Å)
主引用文献NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family.
ChemMedChem, 13, 2018
5NPL
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BU of 5npl by Molmil
Crystal structure of hexameric CBS-CP12 protein from bloom-forming cyanobacteria, Yb-derivative at 2.8 A resolution
分子名称: 10-((2R)-2-HYDROXYPROPYL)-1,4,7,10-TETRAAZACYCLODODECANE 1,4,7-TRIACETIC ACID, Similar to tr|Q8YYT1|Q8YYT1, YTTERBIUM (III) ION
著者Hackenberg, C, Hakanpaa, J, Antonyuk, S.V, Dittmann, E, Lamzin, V.S.
登録日2017-04-17
公開日2018-05-30
最終更新日2018-07-11
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Structural and functional insights into the unique CBS-CP12 fusion protein family in cyanobacteria.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7OAE
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BU of 7oae by Molmil
Cryo-EM structure of the plectasin fibril (double strands)
分子名称: Fungal defensin plectasin
著者Effantin, G.
登録日2021-04-19
公開日2022-04-27
最終更新日2022-11-16
実験手法ELECTRON MICROSCOPY (2 Å)
主引用文献pH- and concentration-dependent supramolecular assembly of a fungal defensin plectasin variant into helical non-amyloid fibrils.
Nat Commun, 13, 2022
7OAG
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BU of 7oag by Molmil
Cryo-EM structure of the plectasin fibril (single strand)
分子名称: Fungal defensin plectasin
著者Effantin, G.
登録日2021-04-19
公開日2022-04-27
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献pH- and concentration-dependent supramolecular assembly of a fungal defensin plectasin variant into helical non-amyloid fibrils.
Nat Commun, 13, 2022
7O76
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BU of 7o76 by Molmil
Reversible supramolecular assembly of the anti-microbial peptide plectasin
分子名称: DI(HYDROXYETHYL)ETHER, Fungal defensin plectasin
著者Pohl, C, Noergaard, N, Harris, P.
登録日2021-04-13
公開日2022-06-29
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.131 Å)
主引用文献pH- and concentration-dependent supramolecular assembly of a fungal defensin plectasin variant into helical non-amyloid fibrils.
Nat Commun, 13, 2022
6Q1Z
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BU of 6q1z by Molmil
Crystal structure of human 1G04 Fab in complex with influenza virus neuraminidase from A/Hunan/02650/2016 (H7N9)
分子名称: 1G04 Fab IgG1 heavy chain, 1G04 Fab kappa light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhu, X, Wilson, I.A.
登録日2019-08-06
公開日2019-10-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.446 Å)
主引用文献Broadly protective human antibodies that target the active site of influenza virus neuraminidase.
Science, 366, 2019
8E6K
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BU of 8e6k by Molmil
2H08 Fab in complex with influenza virus neuraminidase from A/Brevig Mission/1/1918 (H1N1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2H08 fragment antigen binding heavy chain, 2H08 fragment antigen binding light chain, ...
著者Turner, H.L, Ozorowski, G, Ward, A.B.
登録日2022-08-22
公開日2023-08-09
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo.
Immunity, 56, 2023
8E6J
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BU of 8e6j by Molmil
3H03 Fab in complex with influenza virus neuraminidase from A/Brevig Mission/1/1918 (H1N1)
分子名称: 3H03 fragment antigen binding heavy chain, 3H03 fragment antigen binding light chain, Neuraminidase
著者Turner, H.L, Ozorowski, G, Ward, A.B.
登録日2022-08-22
公開日2023-08-09
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo.
Immunity, 56, 2023
8EQA
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BU of 8eqa by Molmil
Crystal structure of human anti-N1 neuraminidase 2H08 Fab
分子名称: 2H08 Fab heavy chain, 2H08 Fab light chain, ZINC ION
著者Zhu, X, Wilson, I.A.
登録日2022-10-07
公開日2023-08-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo.
Immunity, 56, 2023
8EQC
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BU of 8eqc by Molmil
Crystal structure of human anti-N1 neuraminidase 3H03 Fab
分子名称: 3H03 Fab heavy chain, 3H03 Fab light chain, PHOSPHATE ION
著者Zhu, X, Wilson, I.A.
登録日2022-10-07
公開日2023-08-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo.
Immunity, 56, 2023
6V4O
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BU of 6v4o by Molmil
Structure of human 2E01 Fab in complex with influenza virus neuraminidase from B/Phuket/3073/2013
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab heavy chain, Antibody Fab light chain, ...
著者Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-11-28
公開日2020-10-07
最終更新日2020-10-28
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Human Antibodies Targeting Influenza B Virus Neuraminidase Active Site Are Broadly Protective.
Immunity, 53, 2020
6V4N
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BU of 6v4n by Molmil
Structure of human 1G05 Fab in complex with influenza virus neuraminidase from B/Phuket/3073/2013
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab heavy chain, Antibody Fab light chain, ...
著者Dai, Y.N, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-11-28
公開日2020-10-07
最終更新日2020-10-28
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Human Antibodies Targeting Influenza B Virus Neuraminidase Active Site Are Broadly Protective.
Immunity, 53, 2020
2LVG
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BU of 2lvg by Molmil
NMR structure of HCV Non-structural protein AB, NS4B(1-40)
分子名称: Non-structural protein 4B
著者Montserret, R, Penin, F.
登録日2012-07-05
公開日2013-06-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Aminoterminal Amphipathic alpha-Helix AH1 of Hepatitis C Virus Nonstructural Protein 4B Possesses a Dual Role in RNA Replication and Virus Production.
Plos Pathog., 10, 2014
6RMS
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BU of 6rms by Molmil
The Structure of variant D274E of the Mo-insertase domain Cnx1E from Arabidopsis thaliana in complex with AMP
分子名称: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, IMIDAZOLE, ...
著者Krausze, J.
登録日2019-05-07
公開日2020-02-19
最終更新日2024-01-24
実験手法SOLUTION SCATTERING (1.74 Å), X-RAY DIFFRACTION
主引用文献Insights into the Cnx1E catalyzed MPT-AMP hydrolysis.
Biosci.Rep., 40, 2020
5NVD
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BU of 5nvd by Molmil
Crystal structure of hexameric CBS-CP12 protein from bloom-forming cyanobacteria at 2.5 A resolution in P6322 crystal form
分子名称: CBS-CP12
著者Hackenberg, C, Hakanpaa, J, Eigner, C, Antonyuk, S.V, Dittmann, E, Lamzin, V.S.
登録日2017-05-04
公開日2018-05-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and functional insights into the unique CBS-CP12 fusion protein family in cyanobacteria.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
2OMV
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BU of 2omv by Molmil
Crystal structure of InlA S192N Y369S/hEC1 complex
分子名称: CALCIUM ION, CHLORIDE ION, Epithelial-cadherin, ...
著者Wollert, T, Heinz, D.W, Schubert, W.D.
登録日2007-01-23
公開日2007-06-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Extending the host range of Listeria monocytogenes by rational protein design.
Cell(Cambridge,Mass.), 129, 2007
5NMU
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BU of 5nmu by Molmil
Structure of hexameric CBS-CP12 protein from bloom-forming cyanobacteria
分子名称: CBS-CP12, CHLORIDE ION
著者Hackenberg, C, Hakanpaa, J, Antonyuk, S.V, Dittmann, E, Lamzin, V.S.
登録日2017-04-07
公開日2018-05-16
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural and functional insights into the unique CBS-CP12 fusion protein family in cyanobacteria.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
2OMY
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BU of 2omy by Molmil
Crystal structure of InlA S192N/hEC1 complex
分子名称: CALCIUM ION, CHLORIDE ION, Epithelial-cadherin, ...
著者Wollert, T, Heinz, D.W, Schubert, W.D.
登録日2007-01-23
公開日2007-06-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Extending the host range of Listeria monocytogenes by rational protein design.
Cell(Cambridge,Mass.), 129, 2007
2OMW
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BU of 2omw by Molmil
Crystal structure of InlA S192N Y369S/mEC1 complex
分子名称: CHLORIDE ION, Epithelial-cadherin, Internalin-A
著者Wollert, T, Heinz, D.W, Schubert, W.D.
登録日2007-01-23
公開日2007-06-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Extending the host range of Listeria monocytogenes by rational protein design.
Cell(Cambridge,Mass.), 129, 2007
8AXT
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BU of 8axt by Molmil
Sialidases and Fucosidases of Akkermansia muciniphila are key for rapid growth on colonic mucin and nutrient sharing amongst mucin-associated human gut microbiota
分子名称: CALCIUM ION, CHLORIDE ION, Sialidase domain-containing protein
著者Sakanaka, H, Nielsen, T.S, Pichler, M.J, Nordberg Karlsson, E, Abou Hachem, M, Morth, J.P.
登録日2022-08-31
公開日2023-03-01
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Sialidases and fucosidases of Akkermansia muciniphila are crucial for growth on mucin and nutrient sharing with mucus-associated gut bacteria.
Nat Commun, 14, 2023

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