4M3O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4m3o by Molmil](/molmil-images/mine/4m3o) | Crystal structure of K.lactis Rtr1 NTD | 分子名称: | KLLA0F12672p, ZINC ION | 著者 | Hsu, P.L, Yang, W, Zheng, N, Varani, G. | 登録日 | 2013-08-06 | 公開日 | 2014-07-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Rtr1 Is a Dual Specificity Phosphatase That Dephosphorylates Tyr1 and Ser5 on the RNA Polymerase II CTD. J.Mol.Biol., 426, 2014
|
|
3B9O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3b9o by Molmil](/molmil-images/mine/3b9o) | long-chain alkane monooxygenase (LadA) in complex with coenzyme FMN | 分子名称: | Alkane monooxygenase, FLAVIN MONONUCLEOTIDE | 著者 | Li, L, Yang, W, Xu, F, Bartlam, M, Rao, Z. | 登録日 | 2007-11-06 | 公開日 | 2008-01-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of long-chain alkane monooxygenase (LadA) in complex with coenzyme FMN: unveiling the long-chain alkane hydroxylase J.Mol.Biol., 376, 2008
|
|
3B9N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3b9n by Molmil](/molmil-images/mine/3b9n) | Crystal structure of long-chain alkane monooxygenase (LadA) | 分子名称: | Alkane monooxygenase | 著者 | Li, L, Yang, W, Xu, F, Bartlam, M, Rao, Z. | 登録日 | 2007-11-06 | 公開日 | 2008-01-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of long-chain alkane monooxygenase (LadA) in complex with coenzyme FMN: unveiling the long-chain alkane hydroxylase J.Mol.Biol., 376, 2008
|
|
4B3Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4b3q by Molmil](/molmil-images/mine/4b3q) | Structures of HIV-1 RT and RNA-DNA Complex Reveal a Unique RT Conformation and Substrate Interface | 分子名称: | 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, P51 RT, PRIMER DNA, ... | 著者 | Lapkouski, M, Tian, L, Miller, J.T, Le Grice, S.F.J, Yang, W. | 登録日 | 2012-07-25 | 公開日 | 2013-01-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (5 Å) | 主引用文献 | Complexes of HIV-1 RT, Nnrti and RNA/DNA Hybrid Reveal a Structure Compatible with RNA Degradation Nat.Struct.Mol.Biol., 20, 2013
|
|
4B3P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4b3p by Molmil](/molmil-images/mine/4b3p) | Structures of HIV-1 RT and RNA-DNA Complex Reveal a Unique RT Conformation and Substrate Interface | 分子名称: | DNA, P51 RT, REVERSE TRANSCRIPTASE/RIBONUCLEASE H, ... | 著者 | Lapkouski, M, Tian, L, Miller, J.T, Le Grice, S.F.J, Yang, W. | 登録日 | 2012-07-25 | 公開日 | 2013-01-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (4.839 Å) | 主引用文献 | Complexes of HIV-1 RT, Nnrti and RNA/DNA Hybrid Reveal a Structure Compatible with RNA Degradation Nat.Struct.Mol.Biol., 20, 2013
|
|
4B3O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4b3o by Molmil](/molmil-images/mine/4b3o) | Structures of HIV-1 RT and RNA-DNA Complex Reveal a Unique RT Conformation and Substrate Interface | 分子名称: | (-)-6-CHLORO-4-CYCLOPROPYLETHYNYL-4-TRIFLUOROMETHYL-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE, 5'-D(*CP*GP*TP*AP*TP*GP*CP*CP*TP*AP*TP*AP*GP*TP *TP*AP*TP*TP*GP*TP*GP*GP*CP*C)-3', 5'-R(*AP*UP*GP*AP*3DRP*GP*GP*CP*CP*AP*CP*AP*AP*UP*AP *AP*CP*UP*AP*UP*AP*GP*GP*CP*AP*UP*A)-3', ... | 著者 | Lapkouski, M, Tian, L, Miller, J.T, Le Grice, S.F.J, Yang, W. | 登録日 | 2012-07-25 | 公開日 | 2013-01-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Complexes of HIV-1 RT, Nnrti and RNA/DNA Hybrid Reveal a Structure Compatible with RNA Degradation Nat.Struct.Mol.Biol., 20, 2013
|
|
4BAC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4bac by Molmil](/molmil-images/mine/4bac) | prototype foamy virus strand transfer complexes on product DNA | 分子名称: | 5'-D(*AP*GP*GP*AP*GP*CP*CP*AP*AP*GP*AP*CP*GP*GP *AP*TP*CP)-3', 5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP *TP*TP*GP*TP*AP)-3', DNA (38-MER), ... | 著者 | Yin, Z, Lapkouski, M, Yang, W, Craigie, R. | 登録日 | 2012-09-12 | 公開日 | 2012-10-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.263 Å) | 主引用文献 | Assembly of Prototype Foamy Virus Strand Transfer Complexes on Product DNA Bypassing Catalysis of Integration. Protein Sci., 21, 2012
|
|
4BS1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4bs1 by Molmil](/molmil-images/mine/4bs1) | MuB is an AAAplus ATPase that forms helical filaments to control target selection for DNA transposition | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, TRANSCRIPTIONAL REGULATOR (NTRC FAMILY) | 著者 | Mizuno, N, Dramicanin, M, Mizuuchi, M, Adam, J, Wang, Y, Han, Y.W, Yang, W, Steven, A.C, Mizuuchi, K, Ramon-Maiques, S. | 登録日 | 2013-06-06 | 公開日 | 2013-07-03 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (18 Å) | 主引用文献 | Mub is an Aaa+ ATPase that Forms Helical Filaments to Control Target Selection for DNA Transposition. Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
4BT1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4bt1 by Molmil](/molmil-images/mine/4bt1) | MuB is an AAAplus ATPase that forms helical filaments to control target selection for DNA transposition | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, TRANSCRIPTIONAL REGULATOR | 著者 | Mizuno, N, Dramicanin, M, Mizuuchi, M, Adam, J, Wang, Y, Han, Y.W, Yang, W, Steven, A.C, Mizuuchi, K, Ramon-Maiques, S. | 登録日 | 2013-06-12 | 公開日 | 2013-07-03 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (16 Å) | 主引用文献 | Mub is an Aaa+ ATPase that Forms Helical Filaments to Control Target Selection for DNA Transposition. Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
3DJ7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3dj7 by Molmil](/molmil-images/mine/3dj7) | Crystal structure of the mouse Aurora-A catalytic domain (Asn186->Gly, Lys240->Arg, Met302->Leu) in complex with Compound 130. | 分子名称: | 1-(5-{2-[(6-amino-5-bromopyrimidin-4-yl)amino]ethyl}-1,3-thiazol-2-yl)-3-[3-(trifluoromethyl)phenyl]urea, serine/threonine kinase 6 | 著者 | Elling, R.A, Yang, W, Erlanson, D.A, Tangonan, B.T, Hansen, S.K, Romanowski, M.J. | 登録日 | 2008-06-22 | 公開日 | 2009-05-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | New fragment-based drug discovery To be Published
|
|
3DJ5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3dj5 by Molmil](/molmil-images/mine/3dj5) | Crystal structure of the mouse Aurora-A catalytic domain (Asn186->Gly, Lys240->Arg, Met302->Leu) in complex with Compound 290. | 分子名称: | 3-({3-[(6-amino-5-bromopyrimidin-4-yl)sulfanyl]propanoyl}amino)-4-methoxy-N-phenylbenzamide, serine/threonine kinase 6 | 著者 | Elling, R.A, Erlanson, D.A, Yang, W, Tangonan, B.T, Hansen, S.K, Romanowski, M.J. | 登録日 | 2008-06-22 | 公開日 | 2009-05-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | New fragment-based drug discovery To be Published
|
|
3DJ6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3dj6 by Molmil](/molmil-images/mine/3dj6) | Crystal structure of the mouse Aurora-A catalytic domain (Asn186->Gly, Lys240->Arg, Met302->Leu) in complex with Compound 823. | 分子名称: | 4-methoxy-N-phenyl-3-({3-[(1H-pyrrolo[2,3-b]pyridin-5-ylmethyl)sulfanyl]propanoyl}amino)benzamide, serine/threonine kinase 6 | 著者 | Elling, R.A, Erlanson, D.A, Yang, W, Tangonan, B.T, Hansen, S.K, Romanowski, M.J. | 登録日 | 2008-06-22 | 公開日 | 2009-05-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | New fragment-based drug discovery To be Published
|
|
3OFU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ofu by Molmil](/molmil-images/mine/3ofu) | Crystal Structure of Cytochrome P450 CYP101C1 | 分子名称: | (3E)-4-(2,6,6-trimethylcyclohex-1-en-1-yl)but-3-en-2-one, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Zhou, W, Ma, M, Bell, S.G, Yang, W, Hao, Y, Rees, N.H, Bartlam, M, Wong, L.-L, Rao, Z. | 登録日 | 2010-08-16 | 公開日 | 2011-05-04 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural Analysis of CYP101C1 from Novosphingobium aromaticivorans DSM12444. Chembiochem, 12, 2011
|
|
3OFT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3oft by Molmil](/molmil-images/mine/3oft) | Crystal Structure of Cytochrome P450 CYP101C1 | 分子名称: | (2R,5R)-hexane-2,5-diol, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Zhou, W, Ma, M, Bell, S.G, Yang, W, Hao, Y, Rees, N.H, Bartlam, M, Wong, L.-L, Rao, Z. | 登録日 | 2010-08-16 | 公開日 | 2011-07-20 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Analysis of CYP101C1 from Novosphingobium aromaticivorans DSM12444. Chembiochem, 12, 2011
|
|
1NHI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1nhi by Molmil](/molmil-images/mine/1nhi) | Crystal structure of N-terminal 40KD MutL (LN40) complex with ADPnP and one potassium | 分子名称: | 1,2-ETHANEDIOL, DNA mismatch repair protein mutL, MAGNESIUM ION, ... | 著者 | Hu, X, Machius, M, Yang, W. | 登録日 | 2002-12-19 | 公開日 | 2003-06-10 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Monovalent cation dependence and preference of GHKL ATPases and kinases FEBS Lett., 544, 2003
|
|
1K6Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1k6y by Molmil](/molmil-images/mine/1k6y) | Crystal Structure of a Two-Domain Fragment of HIV-1 Integrase | 分子名称: | Integrase, PHOSPHATE ION, POTASSIUM ION, ... | 著者 | Wang, J, Ling, H, Yang, W, Craigie, R. | 登録日 | 2001-10-17 | 公開日 | 2001-12-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein. EMBO J., 20, 2001
|
|
1K99
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1k99 by Molmil](/molmil-images/mine/1k99) | |
1NHH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1nhh by Molmil](/molmil-images/mine/1nhh) | Crystal structure of N-terminal 40KD MutL protein (LN40) complex with ADPnP and one Rubidium | 分子名称: | 1,2-ETHANEDIOL, DNA mismatch repair protein mutL, MAGNESIUM ION, ... | 著者 | Hu, X, Machius, M, Yang, W. | 登録日 | 2002-12-19 | 公開日 | 2003-06-10 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Monovalent cation dependence and preference of GHKL ATPases and kinases FEBS Lett., 544, 2003
|
|
1NHJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1nhj by Molmil](/molmil-images/mine/1nhj) | Crystal structure of N-terminal 40KD MutL/A100P mutant protein complex with ADPnP and one sodium | 分子名称: | DNA mismatch repair protein mutL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Hu, X, Machius, M, Yang, W. | 登録日 | 2002-12-19 | 公開日 | 2003-06-10 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Monovalent cation dependence and preference of GHKL ATPases and kinases FEBS Lett., 544, 2003
|
|
8DOL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dol by Molmil](/molmil-images/mine/8dol) | Mechanism of regulation of the Helicobacter pylori Cagbeta ATPase by CagZ | 分子名称: | Cag pathogenicity island protein (Cag5), DI(HYDROXYETHYL)ETHER, SULFATE ION | 著者 | Wu, X, Zhao, Y, Yang, W, Sun, L, Ye, X, Jiang, M, Wang, Q, Wang, Q, Zhang, X, Wu, Y. | 登録日 | 2022-07-13 | 公開日 | 2023-02-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Mechanism of regulation of the Helicobacter pylori Cag beta ATPase by CagZ. Nat Commun, 14, 2023
|
|
1NNE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1nne by Molmil](/molmil-images/mine/1nne) | Crystal Structure of the MutS-ADPBeF3-DNA complex | 分子名称: | 1,2-ETHANEDIOL, 5'-D(*GP*CP*GP*AP*CP*GP*CP*TP*AP*GP*CP*GP*TP*GP*CP*GP*GP*CP*TP*CP*GP*TP*C)-3', 5'-D(P*GP*GP*AP*CP*GP*AP*GP*CP*CP*GP*CP*CP*GP*CP*TP*AP*GP*CP*GP*TP*CP*G)-3', ... | 著者 | Alani, E, Lee, J.Y, Schofield, M.J, Kijas, A.W, Hsieh, P, Yang, W. | 登録日 | 2003-01-13 | 公開日 | 2003-05-20 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | Crystal structure and biochemical analysis of the MutS-ADP-Beryllium Fluoride complex
suggests a conserved mechanism for ATP interactions in mismatch repair J.Biol.Chem., 278, 2003
|
|
1JXL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jxl by Molmil](/molmil-images/mine/1jxl) | Crystal Structure of a Y-Family DNA Polymerase in a Ternary Complex with DNA Substrates and an Incoming Nucleotide | 分子名称: | 1,2-ETHANEDIOL, 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*T)-3', ... | 著者 | Ling, H, Boudsocq, F, Woodgate, R, Yang, W. | 登録日 | 2001-09-07 | 公開日 | 2001-10-05 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication. Cell(Cambridge,Mass.), 107, 2001
|
|
1Q2O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1q2o by Molmil](/molmil-images/mine/1q2o) | Bovine endothelial nitric oxide synthase N368D mutant heme domain dimer with L-N(omega)-nitroarginine-2,4-L-diaminobutyramide bound | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, CACODYLATE ION, ... | 著者 | Flinspach, M.L, Li, H, Jamal, J, Yang, W, Huang, H, Hah, J.M, Gomez-Vidal, J.A, Litzinger, E.A, Silverman, R.B, Poulos, T.L. | 登録日 | 2003-07-25 | 公開日 | 2004-01-13 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase. Nat.Struct.Mol.Biol., 11, 2004
|
|
1LWW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1lww by Molmil](/molmil-images/mine/1lww) | Borohydride-trapped hOgg1 Intermediate Structure Co-Crystallized with 8-bromoguanine | 分子名称: | 5'-D(*GP*CP*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 8-BROMOGUANINE, ... | 著者 | Fromme, J.C, Bruner, S.D, Yang, W, Karplus, M, Verdine, G.L. | 登録日 | 2002-06-03 | 公開日 | 2003-02-25 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Product-Assisted Catalysis in Base Excision DNA Repair Nat.Struct.Biol., 10, 2003
|
|
1LZZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1lzz by Molmil](/molmil-images/mine/1lzz) | Rat neuronal NOS heme domain with N-isopropyl-N'-hydroxyguanidine bound | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N-ISOPROPYL-N'-HYDROXYGUANIDINE, ... | 著者 | Li, H, Shimizu, H, Flinspach, M, Jamal, J, Yang, W, Xian, M, Cai, T, Wen, E.Z, Jia, Q, Wang, P.G, Poulos, T.L. | 登録日 | 2002-06-11 | 公開日 | 2002-11-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | The Novel Binding Mode of N-Alkyl-N'-Hydroxyguanidine to Neuronal Nitric Oxide
Synthase Provides Mechanistic Insights into NO Biosynthesis Biochemistry, 41, 2002
|
|