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3FCT
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BU of 3fct by Molmil
MATURE METAL CHELATASE CATALYTIC ANTIBODY WITH HAPTEN
分子名称: CADMIUM ION, CALCIUM ION, MAGNESIUM ION, ...
著者Romesberg, F.E, Santarsiero, B.D, Barnes, D, Yin, J, Spiller, B, Schultz, P.G, Stevens, R.C.
登録日1999-06-13
公開日1999-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and kinetic evidence for strain in biological catalysis.
Biochemistry, 37, 1998
3D4S
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BU of 3d4s by Molmil
Cholesterol bound form of human beta2 adrenergic receptor.
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol, Beta-2 adrenergic receptor/T4-lysozyme chimera, ...
著者Hanson, M.A, Cherezov, V, Roth, C.B, Griffith, M.T, Jaakola, V.-P, Chien, E.Y.T, Velasquez, J, Kuhn, P, Stevens, R.C, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR)
登録日2008-05-14
公開日2008-06-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A specific cholesterol binding site is established by the 2.8 A structure of the human beta2-adrenergic receptor.
Structure, 16, 2008
3E1U
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BU of 3e1u by Molmil
The Crystal Structure of the Anti-Viral APOBEC3G Catalytic Domain
分子名称: DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION
著者Holden, L, Prochnow, C, Chang, Y.P, Bransteitter, R, Chelico, L, Sen, U, Stevens, R.C, Goodman, R.F, Chen, X.S.
登録日2008-08-04
公開日2008-10-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications.
Nature, 456, 2008
4JKV
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BU of 4jkv by Molmil
Structure of the human smoothened 7TM receptor in complex with an antitumor agent
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-fluoro-N-methyl-N-{1-[4-(1-methyl-1H-pyrazol-5-yl)phthalazin-1-yl]piperidin-4-yl}-2-(trifluoromethyl)benzamide, DI(HYDROXYETHYL)ETHER, ...
著者Wang, C, Wu, H, Katritch, V, Han, G.W, Huang, X, Liu, W, Siu, F.Y, Roth, B.L, Cherezov, V, Stevens, R.C, GPCR Network (GPCR)
登録日2013-03-11
公開日2013-04-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structure of the human smoothened receptor bound to an antitumour agent.
Nature, 497, 2013
2N2F
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BU of 2n2f by Molmil
Solution NMR structure of Dynorphin 1-13 bound to Kappa Opioid Receptor
分子名称: Dynorphin A(1-13)
著者O'Connor, C, White, K, Doncescu, N, Didenko, T, Roth, B.L, Czaplicki, G, Stevens, R.C, Wuthrich, K, Milon, A.
登録日2015-05-06
公開日2015-09-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR structure and dynamics of the agonist dynorphin peptide bound to the human kappa opioid receptor.
Proc.Natl.Acad.Sci.USA, 112, 2015
4L6R
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BU of 4l6r by Molmil
Structure of the class B human glucagon G protein coupled receptor
分子名称: DI(HYDROXYETHYL)ETHER, Soluble cytochrome b562 and Glucagon receptor chimera
著者Siu, F.Y, He, M, de Graaf, C, Han, G.W, Yang, D, Zhang, Z, Zhou, C, Xu, Q, Wacker, D, Joseph, J.S, Liu, W, Lau, J, Cherezov, V, Katritch, V, Wang, M.W, Stevens, R.C, GPCR Network (GPCR)
登録日2013-06-12
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of the human glucagon class B G-protein-coupled receptor.
Nature, 499, 2013
4J6S
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BU of 4j6s by Molmil
14-3-3gamma complexed with the N-terminal sequence of tyrosine hydroxylase (residues 1-43)
分子名称: 14-3-3 protein gamma, N-terminal motif of tyrosine hydroxylase
著者Mileni, M, Martinez, A, Stevens, R.C.
登録日2013-02-11
公開日2013-10-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.08 Å)
主引用文献The N-terminal sequence of tyrosine hydroxylase is a conformationally versatile motif that binds 14-3-3 proteins and membranes.
J.Mol.Biol., 426, 2014
2OG3
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BU of 2og3 by Molmil
structure of the rna binding domain of n protein from SARS coronavirus in cubic crystal form
分子名称: Nucleocapsid protein
著者Saikatendu, K, Joseph, J, Subramanian, V, Neuman, B, Buchmeier, M, Stevens, R.C, Kuhn, P.
登録日2007-01-05
公開日2007-04-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Ribonucleocapsid formation of severe acute respiratory syndrome coronavirus through molecular action of the N-terminal domain of N protein.
J.Virol., 81, 2007
4J5P
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BU of 4j5p by Molmil
Crystal Structure of a Covalently Bound alpha-Ketoheterocycle Inhibitor (Phenhexyl/Oxadiazole/Pyridine) to a Humanized Variant of Fatty Acid Amide Hydrolase
分子名称: (1S)-1-{5-[5-(bromomethyl)pyridin-2-yl]-1,3-oxazol-2-yl}-7-phenylheptan-1-ol, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Otrubova, K, Brown, M, McCormick, M.S, Han, G.W, O'Neal, S.T, Cravatt, B.F, Stevens, R.C, Lichtman, A.H, Boger, D.L.
登録日2013-02-08
公開日2013-05-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Rational design of Fatty Acid amide hydrolase inhibitors that act by covalently bonding to two active site residues.
J.Am.Chem.Soc., 135, 2013
2OZK
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BU of 2ozk by Molmil
Structure of an N-Terminal Truncated Form of Nendou (NSP15) From SARS-CORONAVIRUS
分子名称: Uridylate-specific endoribonuclease
著者Saikatendu, K, Joseph, J, Subramanian, V, Neuman, B, Buchmeier, M, Stevens, R.C, Kuhn, P.
登録日2007-02-26
公開日2007-05-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of a monomeric form of severe acute respiratory syndrome coronavirus endonuclease nsp15 suggests a role for hexamerization as an allosteric switch.
J.Virol., 81, 2007
2OFZ
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BU of 2ofz by Molmil
Ultrahigh Resolution Crystal Structure of RNA Binding Domain of SARS Nucleopcapsid (N Protein) at 1.1 Angstrom Resolution in Monoclinic Form.
分子名称: 1,2-ETHANEDIOL, Nucleocapsid protein
著者Saikatendu, K, Joseph, J, Subramanian, V, Neuman, B, Buchmeier, M, Stevens, R.C, Kuhn, P.
登録日2007-01-04
公開日2007-04-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.17 Å)
主引用文献Ribonucleocapsid formation of severe acute respiratory syndrome coronavirus through molecular action of the N-terminal domain of N protein.
J.Virol., 81, 2007
4MBS
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BU of 4mbs by Molmil
Crystal Structure of the CCR5 Chemokine Receptor
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4,4-difluoro-N-[(1S)-3-{(3-exo)-3-[3-methyl-5-(propan-2-yl)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]oct-8-yl}-1-phenylpropyl]cyclohexanecarboxamide, Chimera protein of C-C chemokine receptor type 5 and Rubredoxin, ...
著者Tan, Q, Zhu, Y, Han, G.W, Li, J, Fenalti, G, Liu, H, Cherezov, V, Stevens, R.C, GPCR Network (GPCR), Zhao, Q, Wu, B.
登録日2013-08-19
公開日2013-09-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structure of the CCR5 chemokine receptor-HIV entry inhibitor maraviroc complex.
Science, 341, 2013
2NP0
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BU of 2np0 by Molmil
Crystal structure of the Botulinum neurotoxin type B complexed with synaptotagamin-II ectodomain
分子名称: Botulinum neurotoxin type B, CALCIUM ION, CHLORIDE ION, ...
著者Chai, Q, Arndt, J.W, Stevens, R.C.
登録日2006-10-26
公開日2006-12-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Structural basis of cell surface receptor recognition by botulinum neurotoxin B.
Nature, 444, 2006
1E74
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BU of 1e74 by Molmil
NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN IM1 POINT MUTATION VARIANT R11E
分子名称: ALPHA-CONOTOXIN IM1(R11E)
著者Rogers, J.P, Luginbuhl, P, Pemberton, K, Harty, P, Wemmer, D.E, Stevens, R.C.
登録日2000-08-24
公開日2000-12-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure-Activity Relationships in a Peptidic Alpha7 Nicotinic Acetylcholine Receptor Antagonist
J.Mol.Biol., 304, 2000
1E75
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NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN IM1 POINT MUTATION VARIANT R7L
分子名称: ALPHA-CONOTOXIN IM1(R7L)
著者Rogers, J.P, Luginbuhl, P, Pemberton, K, Harty, P, Wemmer, D.E, Stevens, R.C.
登録日2000-08-24
公開日2000-12-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure-Activity Relationships in a Peptidic Alpha7 Nicotinic Acetylcholine Receptor Antagonist
J.Mol.Biol., 304, 2000
1E76
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NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN IM1 POINT MUTATION VARIANT D5N
分子名称: ALPHA-CONOTOXIN IM1(D5N)
著者Rogers, J.P, Luginbuhl, P, Pemberton, K, Harty, P, Wemmer, D.E, Stevens, R.C.
登録日2000-08-24
公開日2000-12-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure-Activity Relationships in a Peptidic Alpha7 Nicotinic Acetylcholine Receptor Antagonist
J.Mol.Biol., 304, 2000
1IM1
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BU of 1im1 by Molmil
NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN IM1, 20 STRUCTURES
分子名称: ALPHA-CONOTOXIN IM1
著者Rogers, J.P, Luginbuhl, P, Shen, G.S, Mccabe, R.T, Stevens, R.C, Wemmer, D.E.
登録日1998-11-18
公開日1999-06-15
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献NMR solution structure of alpha-conotoxin ImI and comparison to other conotoxins specific for neuronal nicotinic acetylcholine receptors.
Biochemistry, 38, 1999
1KEM
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BU of 1kem by Molmil
CATALYTIC ANTIBODY 28B4 FAB FRAGMENT
分子名称: 28B4 FAB
著者Hsieh-Wilson, L.C, Schultz, P.G, Stevens, R.C.
登録日1996-04-16
公開日1996-12-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Insights into antibody catalysis: structure of an oxygenation catalyst at 1.9-angstrom resolution.
Proc.Natl.Acad.Sci.USA, 93, 1996
1LTU
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BU of 1ltu by Molmil
CRYSTAL STRUCTURE OF CHROMOBACTERIUM VIOLACEUM, APO (NO IRON BOUND) STRUCTURE
分子名称: PHENYLALANINE-4-HYDROXYLASE
著者Erlandsen, H, Kim, J.Y, Patch, M.G, Han, A, Volner, A, Abu-Omar, M.M, Stevens, R.C.
登録日2002-05-20
公開日2002-07-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates.
J.Mol.Biol., 320, 2002
1LTZ
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CRYSTAL STRUCTURE OF CHROMOBACTERIUM VIOLACEUM PHENYLALANINE HYDROXYLASE, STRUCTURE HAS BOUND IRON (III) AND OXIDIZED COFACTOR 7,8-DIHYDROBIOPTERIN
分子名称: 7,8-DIHYDROBIOPTERIN, CHLORIDE ION, FE (III) ION, ...
著者Erlandsen, H, Kim, J.Y, Patch, M.G, Han, A, Volner, A, Abu-Omar, M.M, Stevens, R.C.
登録日2002-05-21
公開日2002-07-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates.
J.Mol.Biol., 320, 2002
1KEL
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BU of 1kel by Molmil
CATALYTIC ANTIBODY 28B4 FAB FRAGMENT COMPLEXED WITH HAPTEN (1-[N-4'-NITROBENZYL-N-4'-CARBOXYBUTYLAMINO] METHYLPHOSPHONIC ACID)
分子名称: 1-[N-4'-NITROBENZYL-N-4'-CARBOXYBUTYLAMINO]METHYLPHOSPHONIC ACID, 28B4 FAB
著者Hsieh-Wilson, L.C, Schultz, P.G, Stevens, R.C.
登録日1996-04-16
公開日1996-12-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Insights into antibody catalysis: structure of an oxygenation catalyst at 1.9-angstrom resolution.
Proc.Natl.Acad.Sci.USA, 93, 1996
1LTV
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BU of 1ltv by Molmil
CRYSTAL STRUCTURE OF CHROMOBACTERIUM VIOLACEUM PHENYLALANINE HYDROXYLASE, STRUCTURE WITH BOUND OXIDIZED Fe(III)
分子名称: FE (III) ION, PHENYLALANINE-4-HYDROXYLASE
著者Erlandsen, H, Kim, J.Y, Patch, M.G, Han, A, Volner, A, Abu-Omar, M.M, Stevens, R.C.
登録日2002-05-20
公開日2002-07-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates.
J.Mol.Biol., 320, 2002
2IDY
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BU of 2idy by Molmil
NMR Structure of the SARS-CoV non-structural protein nsp3a
分子名称: NSP3
著者Serrano, P, Almeida, M.S, Johnson, M.A, Horst, R, Herrmann, T, Joseph, J, Saikatendu, K, Subramanian, V, Stevens, R.C, Kuhn, P, Wuthrich, K, Joint Center for Structural Genomics (JCSG)
登録日2006-09-15
公開日2006-12-05
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Nuclear magnetic resonance structure of the N-terminal domain of nonstructural protein 3 from the severe acute respiratory syndrome coronavirus.
J.Virol., 81, 2007
2GRI
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BU of 2gri by Molmil
NMR Structure of the SARS-CoV non-structural protein nsp3a
分子名称: NSP3
著者Serrano, P, Almeida, M.S, Johnson, M.A, Herrmann, T, Saikatendu, K.S, Joseph, J, Subramanian, V, Neuman, B.W, Buchmeier, M.J, Stevens, R.C, Kuhn, P, Wuthrich, K, Joint Center for Structural Genomics (JCSG)
登録日2006-04-24
公開日2006-12-19
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Nuclear magnetic resonance structure of the N-terminal domain of nonstructural protein 3 from the severe acute respiratory syndrome coronavirus.
J.Virol., 81, 2007
1DMW
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BU of 1dmw by Molmil
CRYSTAL STRUCTURE OF DOUBLE TRUNCATED HUMAN PHENYLALANINE HYDROXYLASE WITH BOUND 7,8-DIHYDRO-L-BIOPTERIN
分子名称: 7,8-DIHYDROBIOPTERIN, FE (III) ION, PHENYLALANINE HYDROXYLASE
著者Erlandsen, H, Stevens, R.C, Flatmark, T.
登録日1999-12-15
公開日2000-03-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure and site-specific mutagenesis of pterin-bound human phenylalanine hydroxylase.
Biochemistry, 39, 2000

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