2EKE
 
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2ASS
 | | Crystal structure of the Skp1-Skp2-Cks1 complex | | 分子名称: | BENZAMIDINE, Cyclin-dependent kinases regulatory subunit 1, PHOSPHATE ION, ... | | 著者 | Hao, B, Zhang, N, Schulman, B.A, Wu, G, Pagano, M, Pavletich, N.P. | | 登録日 | 2005-08-24 | | 公開日 | 2005-10-18 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Basis of the Cks1-Dependent Recognition of p27(Kip1) by the SCF(Skp2) Ubiquitin Ligase.
Mol.Cell, 20, 2005
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2AST
 | | Crystal structure of Skp1-Skp2-Cks1 in complex with a p27 peptide | | 分子名称: | BENZAMIDINE, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinases regulatory subunit 1, ... | | 著者 | Hao, B, Zhang, N, Schulman, B.A, Wu, G, Pagano, M, Pavletich, N.P. | | 登録日 | 2005-08-24 | | 公開日 | 2005-10-18 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Basis of the Cks1-Dependent Recognition of p27(Kip1) by the SCF(Skp2) Ubiquitin Ligase.
Mol.Cell, 20, 2005
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6YVA
 | | PLpro-C111S with mISG15 | | 分子名称: | Replicase polyprotein 1a, Ubiquitin-like protein ISG15, ZINC ION | | 著者 | Shin, D, Dikic, I. | | 登録日 | 2020-04-28 | | 公開日 | 2020-05-13 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | | 主引用文献 | Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity.
Nature, 587, 2020
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5KHU
 | | Model of human Anaphase-promoting complex/Cyclosome (APC15 deletion mutant), in complex with the Mitotic checkpoint complex (APC/C-CDC20-MCC) based on cryo EM data at 4.8 Angstrom resolution | | 分子名称: | Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... | | 著者 | Yamaguchi, M, VanderLinden, R, Dube, P, Stark, H, Schulman, B. | | 登録日 | 2016-06-15 | | 公開日 | 2016-09-07 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation.
Mol.Cell, 63, 2016
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2MT5
 | | Isolated Ring domain | | 分子名称: | Anaphase-promoting complex subunit 11, ZINC ION | | 著者 | Brown, N.G, Watson, E.R, Weissman, F, Royappa, G, Schulman, B, Jarvis, M, Vanderlinden, R, Frye, J.J, Qiao, R, Petzold, G, Peters, J, Stark, H. | | 登録日 | 2014-08-13 | | 公開日 | 2014-10-29 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Mechanism of Polyubiquitination by Human Anaphase-Promoting Complex: RING Repurposing for Ubiquitin Chain Assembly.
Mol.Cell, 56, 2014
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5V4K
 | | Crystal structure of NEDD4 LIR-fused human LC3B_2-119 | | 分子名称: | GLYCEROL, Microtubule-associated proteins 1A/1B light chain 3B,Microtubule-associated proteins 1A/1B light chain 3B,Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION | | 著者 | Qiu, Y, Zheng, Y, Schulman, B. | | 登録日 | 2017-03-09 | | 公開日 | 2017-05-17 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | | 主引用文献 | Insights into links between autophagy and the ubiquitin system from the structure of LC3B bound to the LIR motif from the E3 ligase NEDD4.
Protein Sci., 26, 2017
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6OB1
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6NXL
 | | Ubiquitin binding variants | | 分子名称: | Polyubiquitin-B | | 著者 | Miller, D.J, Watson, E.R. | | 登録日 | 2019-02-08 | | 公開日 | 2020-01-15 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.803 Å) | | 主引用文献 | Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6NXK
 | | Ubiquitin binding variants | | 分子名称: | Anaphase-promoting complex subunit 2, Polyubiquitin-C | | 著者 | Miller, D.J, Watson, E.R. | | 登録日 | 2019-02-08 | | 公開日 | 2020-01-15 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site.
Proc.Natl.Acad.Sci.USA, 116, 2019
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5C7J
 | | CRYSTAL STRUCTURE OF NEDD4 WITH A UB VARIANT | | 分子名称: | E3 ubiquitin-protein ligase NEDD4, Polyubiquitin-C | | 著者 | Walker, J.R, Hu, J, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2015-06-24 | | 公開日 | 2016-03-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
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5C7M
 | | CRYSTAL STRUCTURE OF E3 LIGASE ITCH WITH A UB VARIANT | | 分子名称: | E3 ubiquitin-protein ligase Itchy homolog, Polyubiquitin-C | | 著者 | Walker, J.R, Hu, J, Dong, A, Wernimont, A, Zhang, W, Sidhu, S, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC) | | 登録日 | 2015-06-24 | | 公開日 | 2016-03-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | | 主引用文献 | System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
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5IFR
 | | Structure of the stable UBE2D3-UbDha conjugate | | 分子名称: | GLYCEROL, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D3 | | 著者 | Pruneda, J.N, Mulder, M.P.C, Witting, K, Ovaa, H, Komander, D. | | 登録日 | 2016-02-26 | | 公開日 | 2016-05-11 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes.
Nat.Chem.Biol., 12, 2016
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