6SNK
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![BU of 6snk by Molmil](/molmil-images/mine/6snk) | Crystal structure of the Collagen VI alpha3 N2 domain | 分子名称: | Collagen alpha-3(VI) chain | 著者 | Gebauer, J.M, Degefa, H.S, Paulsson, M, Wagener, R, Baumann, U. | 登録日 | 2019-08-26 | 公開日 | 2020-07-29 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of a collagen VI alpha 3 chain VWA domain array: adaptability and functional implications of myopathy causing mutations. J.Biol.Chem., 295, 2020
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6ZFO
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![BU of 6zfo by Molmil](/molmil-images/mine/6zfo) | Association of two complexes of largely structurally disordered Spike ectodomain with bound EY6A Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, EY6A heavy chain, EY6A light chain, ... | 著者 | Duyvesteyn, H.M.E, Zhou, D, Zhao, Y, Fry, E.E, Ren, J, Stuart, D.I. | 登録日 | 2020-06-17 | 公開日 | 2020-07-08 | 最終更新日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient. Nat.Struct.Mol.Biol., 27, 2020
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6ZDH
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![BU of 6zdh by Molmil](/molmil-images/mine/6zdh) | SARS-CoV-2 Spike glycoprotein in complex with a neutralizing antibody EY6A Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EY6A heavy chain, ... | 著者 | Duyvesteyn, H.M.E, Zhou, D, Zhao, Y, Fry, E.E, Ren, J, Stuart, D.I. | 登録日 | 2020-06-14 | 公開日 | 2020-07-01 | 最終更新日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient. Nat.Struct.Mol.Biol., 27, 2020
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6Z43
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![BU of 6z43 by Molmil](/molmil-images/mine/6z43) | Cryo-EM Structure of SARS-CoV-2 Spike : H11-D4 Nanobody Complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody, ... | 著者 | Ruza, R.R, Duyvesteyn, H.M.E, Shah, P, Carrique, L, Ren, J, Malinauskas, T, Zhou, D, Stuart, D.I, Naismith, J.H. | 登録日 | 2020-05-22 | 公開日 | 2020-06-03 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis for a potent neutralising single-domain antibody that blocks SARS-CoV-2 binding to its receptor ACE2 To Be Published
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6ZH9
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![BU of 6zh9 by Molmil](/molmil-images/mine/6zh9) | Ternary complex CR3022 H11-H4 and RBD (SARS-CoV-2) | 分子名称: | CR3022 Light chain, CR3022 heavy, Nanobody H11-H4, ... | 著者 | Naismith, J.H, Mikolajek, H, Le Bas, A. | 登録日 | 2020-06-21 | 公開日 | 2020-09-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | 主引用文献 | Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2. Nat.Struct.Mol.Biol., 27, 2020
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6ZCZ
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![BU of 6zcz by Molmil](/molmil-images/mine/6zcz) | Crystal structure of receptor binding domain of SARS-CoV-2 Spike glycoprotein in ternary complex with EY6A Fab and a nanobody. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, EY6A heavy chain, ... | 著者 | Zhou, D, Zhao, Y, Fry, E.E, Ren, J, Stuart, D.I. | 登録日 | 2020-06-12 | 公開日 | 2020-06-24 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient. Nat.Struct.Mol.Biol., 27, 2020
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7B3Y
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![BU of 7b3y by Molmil](/molmil-images/mine/7b3y) | Structure of a nanoparticle for a COVID-19 vaccine candidate | 分子名称: | Fibronectin binding protein,2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase | 著者 | Duyvesteyn, H.M.E, Stuart, D.I. | 登録日 | 2020-12-01 | 公開日 | 2021-01-13 | 最終更新日 | 2021-02-03 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses. Nat Commun, 12, 2021
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6ZDG
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![BU of 6zdg by Molmil](/molmil-images/mine/6zdg) | Association of three complexes of largely structurally disordered Spike ectodomain with bound EY6A Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, EY6A heavy chain, EY6A light chain, ... | 著者 | Duyvesteyn, H.M.E, Zhou, D, Zhao, Y, Fry, E.E, Ren, J, Stuart, D.I. | 登録日 | 2020-06-14 | 公開日 | 2020-07-29 | 最終更新日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient. Nat.Struct.Mol.Biol., 27, 2020
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6ZER
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![BU of 6zer by Molmil](/molmil-images/mine/6zer) | Crystal structure of receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with EY6A Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, EY6A heavy chain, EY6A light chain, ... | 著者 | Zhou, D, Zhao, Y, Fry, E.E, Ren, J, Stuart, D.I. | 登録日 | 2020-06-16 | 公開日 | 2020-06-24 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient. Nat.Struct.Mol.Biol., 27, 2020
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5EYT
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![BU of 5eyt by Molmil](/molmil-images/mine/5eyt) | Crystal Structure of Adenylosuccinate Lyase from Schistosoma mansoni in complex with AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, Adenylosuccinate lyase | 著者 | Romanello, L, Torini, J.R, Bird, L, Nettleship, J, Owens, R, Reddivari, Y, Brandao-Neto, J, Pereira, H.M. | 登録日 | 2015-11-25 | 公開日 | 2016-11-30 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.3649 Å) | 主引用文献 | Structural and kinetic analysis of Schistosoma mansoni Adenylosuccinate Lyase (SmADSL). Mol. Biochem. Parasitol., 214, 2017
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6IAK
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![BU of 6iak by Molmil](/molmil-images/mine/6iak) | The crystal structure of the chicken CREB3 bZIP | 分子名称: | Uncharacterized protein | 著者 | Sabaratnam, K, Renner, M. | 登録日 | 2018-11-26 | 公開日 | 2019-12-11 | 最終更新日 | 2020-06-24 | 実験手法 | X-RAY DIFFRACTION (3.95 Å) | 主引用文献 | Insights from the crystal structure of the chicken CREB3 bZIP suggest that members of the CREB3 subfamily transcription factors may be activated in response to oxidative stress. Protein Sci., 28, 2019
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7S6E
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![BU of 7s6e by Molmil](/molmil-images/mine/7s6e) | Crystal structure of UrtA from Synechococcus CC9311 in complex with urea and calcium | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | 著者 | Shah, B.S, Mikolajek, H, Mykhaylyk, V, Orr, C.M, Owens, R.J, Paulsen, I.T. | 登録日 | 2021-09-14 | 公開日 | 2021-10-13 | 実験手法 | X-RAY DIFFRACTION (1.973 Å) | 主引用文献 | Crystal structure of UrtA from Synechococcus CC9311 in complex with urea and calcium To Be Published
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7S6F
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![BU of 7s6f by Molmil](/molmil-images/mine/7s6f) | Crystal structure of UrtA1 from Synechococcus WH8102 in complex with urea and calcium | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Putative urea ABC transporter, ... | 著者 | Shah, B.S, Mikolajek, H, Orr, C.M, Mykhaylyk, V, Owens, R.J, Paulsen, I.T. | 登録日 | 2021-09-14 | 公開日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of UrtA1 from Synechococcus WH8102 in complex with urea and calcium To Be Published
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4IWN
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![BU of 4iwn by Molmil](/molmil-images/mine/4iwn) | Crystal structure of a putative methyltransferase CmoA in complex with a novel SAM derivative | 分子名称: | (2S)-4-[{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}(carboxylatomethyl)sulfonio] -2-ammoniobutanoate, (4S)-2-METHYL-2,4-PENTANEDIOL, tRNA (cmo5U34)-methyltransferase | 著者 | Aller, P, Lobley, C.M, Byrne, R.T, Antson, A.A, Waterman, D.G. | 登録日 | 2013-01-24 | 公開日 | 2013-05-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | S-Adenosyl-S-carboxymethyl-L-homocysteine: a novel cofactor found in the putative tRNA-modifying enzyme CmoA. Acta Crystallogr.,Sect.D, 69, 2013
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8QZ2
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![BU of 8qz2 by Molmil](/molmil-images/mine/8qz2) | Crystal structure of human two pore domain potassium ion channel TREK-2 (K2P10.1) in complex with an inhibitory nanobody (Nb61) | 分子名称: | Nanobody 61, POTASSIUM ION, Potassium channel subfamily K member 10 | 著者 | Baronina, A, Pike, A.C.W, Rodstrom, K.E.J, Ang, J, Bushell, S.R, Chalk, R, Mukhopadhyay, S.M.M, Pardon, E, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Burgess-Brown, N.A, Tucker, S.J, Steyaert, J, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2023-10-26 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation. Nat Commun, 15, 2024
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8QZ1
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![BU of 8qz1 by Molmil](/molmil-images/mine/8qz1) | Crystal structure of human two pore domain potassium ion channel TREK-2 (K2P10.1) in complex with a nanobody (Nb58) | 分子名称: | Isoform B of Potassium channel subfamily K member 10, Nanobody 58, POTASSIUM ION | 著者 | Rodstrom, K.E.J, Pike, A.C.W, Baronina, A, Ang, J, Bushell, S.R, Chalk, R, Mukhopadhyay, S.M.M, Pardon, E, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Burgess-Brown, N.A, Tucker, S.J, Steyaert, J, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2023-10-26 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.588 Å) | 主引用文献 | Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation. Nat Commun, 15, 2024
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8QZ3
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![BU of 8qz3 by Molmil](/molmil-images/mine/8qz3) | Crystal structure of human two pore domain potassium ion channel TREK-2 (K2P10.1) in complex with an activatory nanobody (Nb67) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Nanobody 67, POTASSIUM ION, ... | 著者 | Baronina, A, Pike, A.C.W, Rodstrom, K.E.J, Ang, J, Bushell, S.R, Chalk, R, Mukhopadhyay, S.M.M, Pardon, E, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Burgess-Brown, N.A, Tucker, S.J, Steyaert, J, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2023-10-26 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation. Nat Commun, 15, 2024
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8QZ4
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![BU of 8qz4 by Molmil](/molmil-images/mine/8qz4) | Crystal structure of human two pore domain potassium ion channel TREK-2 (K2P10.1) in complex with an activatory nanobody (Nb76) | 分子名称: | BARIUM ION, CHOLESTEROL HEMISUCCINATE, Nanobody 76, ... | 著者 | Rodstrom, K.E.J, Pike, A.C.W, Baronina, A, Ang, J, Bushell, S.R, Chalk, R, Mukhopadhyay, S.M.M, Pardon, E, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Burgess-Brown, N.A, Tucker, S.J, Steyaert, J, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2023-10-26 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation. Nat Commun, 15, 2024
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7QUR
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![BU of 7qur by Molmil](/molmil-images/mine/7qur) | SARS-CoV-2 Spike with ethylbenzamide-tri-iodo Siallyllactose, C3 symmetry | 分子名称: | 2,3,5-tris(iodanyl)benzamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Naismith, J.H, Yang, Y, Liu, J.W. | 登録日 | 2022-01-18 | 公開日 | 2022-06-01 | 最終更新日 | 2022-08-03 | 実験手法 | ELECTRON MICROSCOPY (2.27 Å) | 主引用文献 | Pathogen-sugar interactions revealed by universal saturation transfer analysis. Science, 377, 2022
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7QUS
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![BU of 7qus by Molmil](/molmil-images/mine/7qus) | SARS-CoV-2 Spike, C3 symmetry | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, ... | 著者 | Naismith, J.H, Yang, Y, Liu, J.W. | 登録日 | 2022-01-18 | 公開日 | 2022-06-08 | 最終更新日 | 2022-08-03 | 実験手法 | ELECTRON MICROSCOPY (2.39 Å) | 主引用文献 | Pathogen-sugar interactions revealed by universal saturation transfer analysis. Science, 377, 2022
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6ZBP
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![BU of 6zbp by Molmil](/molmil-images/mine/6zbp) | H11-H4 complex with SARS-CoV-2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, H11-H4, SULFATE ION, ... | 著者 | Naismith, J.H, Huo, J, Mikolajek, H, Ward, P, Dumoux, M, Owens, R.J, LeBas, A. | 登録日 | 2020-06-08 | 公開日 | 2020-07-29 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | H11-D4 complex with SARS-CoV-2 RBD To Be Published
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8CHS
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![BU of 8chs by Molmil](/molmil-images/mine/8chs) | |
7NQK
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![BU of 7nqk by Molmil](/molmil-images/mine/7nqk) | Cryo-EM structure of the mammalian peptide transporter PepT2 | 分子名称: | Solute carrier family 15 member 2, nanobody | 著者 | Parker, J.L, Deme, J.C, Lea, S.M, Newstead, S. | 登録日 | 2021-03-01 | 公開日 | 2021-07-07 | 最終更新日 | 2021-10-13 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM structure of PepT2 reveals structural basis for proton-coupled peptide and prodrug transport in mammals. Sci Adv, 7, 2021
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8CD0
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![BU of 8cd0 by Molmil](/molmil-images/mine/8cd0) | Human heparan sulfate N-deacetylase-N-sulfotransferase 1 in complex with calcium, 3'-phosphoadenosine-5'-phosphosulfate, and nanobody nAb7 (composite map and model) | 分子名称: | ADENOSINE-3'-5'-DIPHOSPHATE, Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1, CALCIUM ION, ... | 著者 | Mycroft-West, C.J, Wu, L. | 登録日 | 2023-01-29 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (2.42 Å) | 主引用文献 | Structural and mechanistic characterization of bifunctional heparan sulfate N-deacetylase-N-sulfotransferase 1. Nat Commun, 15, 2024
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8CCY
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![BU of 8ccy by Molmil](/molmil-images/mine/8ccy) | |