3CSP
| Crystal structure of the DM2 mutant of myelin oligodendrocyte glycoprotein | 分子名称: | Myelin-oligodendrocyte glycoprotein | 著者 | Breithaupt, C, Schafer, B, Pellkofer, H, Huber, R, Linington, C, Jacob, U. | 登録日 | 2008-04-10 | 公開日 | 2008-10-21 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Demyelinating myelin oligodendrocyte glycoprotein-specific autoantibody response is focused on one dominant conformational epitope region in rodents J.Immunol., 181, 2008
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4W9Z
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2UX7
| Pseudoazurin with engineered amicyanin ligand loop, reduced form, pH 7.5 | 分子名称: | CHLORIDE ION, COPPER (II) ION, GLYCEROL, ... | 著者 | Velarde, M, Huber, R, Yanagisawa, S, Dennison, C, Messerschmidt, A. | 登録日 | 2007-03-27 | 公開日 | 2007-08-21 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Influence of loop shortening on the metal binding site of cupredoxin pseudoazurin. Biochemistry, 46, 2007
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2UX6
| Pseudoazurin with engineered amicyanin ligand loop, oxidized form, pH 7.5 | 分子名称: | CHLORIDE ION, COPPER (II) ION, GLYCEROL, ... | 著者 | Velarde, M, Huber, R, Yanagisawa, S, Dennison, C, Messerschmidt, A. | 登録日 | 2007-03-27 | 公開日 | 2007-08-21 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Influence of Loop Shortening on the Metal Binding Site of Cupredoxin Pseudoazurin. Biochemistry, 46, 2007
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2UXF
| Pseudoazurin with engineered amicyanin ligand loop, oxidized form, pH 5.5 | 分子名称: | CHLORIDE ION, COPPER (II) ION, GLYCEROL, ... | 著者 | Velarde, M, Huber, R, Yanagisawa, S, Dennison, C, Messerschmidt, A. | 登録日 | 2007-03-28 | 公開日 | 2007-08-21 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Influence of Loop Shortening on the Metal Binding Site of Cupredoxin Pseudoazurin. Biochemistry, 46, 2007
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2UXG
| Pseudoazurin with engineered amicyanin ligand loop, reduced form, pH 5.5 | 分子名称: | CHLORIDE ION, COPPER (II) ION, GLYCEROL, ... | 著者 | Velarde, M, Huber, R, Yanagisawa, S, Dennison, C, Messerschmidt, A. | 登録日 | 2007-03-28 | 公開日 | 2007-08-21 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Influence of Loop Shortening on the Metal Binding Site of Cupredoxin Pseudoazurin. Biochemistry, 46, 2007
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2OQ5
| Crystal structure of DESC1, a new member of the type II transmembrane serine proteinases family | 分子名称: | BENZAMIDINE, Transmembrane protease, serine 11E | 著者 | Kyrieleis, O.J.P, Huber, R, Madison, E.L, Jacob, U. | 登録日 | 2007-01-31 | 公開日 | 2007-04-10 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Crystal structure of the catalytic domain of DESC1, a new member of the type II transmembrane serine proteinase family. Febs J., 274, 2007
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3C7M
| Crystal structure of reduced DsbL | 分子名称: | CADMIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Stirnimann, C.U, Grimshaw, J.P.A, Glockshuber, R, Grutter, M.G, Capitani, G. | 登録日 | 2008-02-07 | 公開日 | 2008-07-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | DsbL and DsbI form a specific dithiol oxidase system for periplasmic arylsulfate sulfotransferase in uropathogenic Escherichia coli. J.Mol.Biol., 380, 2008
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3GPJ
| Crystal structure of the yeast 20S proteasome in complex with syringolin B | 分子名称: | N-{[(1S)-2-methyl-1-{[(5S,8S)-5-(1-methylethyl)-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]carbamoyl}propyl]carbamoyl}-L-valine, Proteasome component C1, Proteasome component C11, ... | 著者 | Groll, M, Huber, R, Kaiser, M. | 登録日 | 2009-03-23 | 公開日 | 2009-06-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Synthetic and structural studies on syringolin A and B reveal critical determinants of selectivity and potency of proteasome inhibition Proc.Natl.Acad.Sci.USA, 106, 2009
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3MH5
| HtrA proteases are activated by a conserved mechanism that can be triggered by distinct molecular cues | 分子名称: | DIISOPROPYL PHOSPHONATE, Protease do | 著者 | Krojer, T, Sawa, J, Huber, R, Clausen, T. | 登録日 | 2010-04-07 | 公開日 | 2010-06-30 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues Nat.Struct.Mol.Biol., 17, 2010
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1TGC
| ON THE DISORDERED ACTIVATION DOMAIN IN TRYPSINOGEN. CHEMICAL LABELLING AND LOW-TEMPERATURE CRYSTALLOGRAPHY | 分子名称: | CALCIUM ION, TRYPSINOGEN | 著者 | Walter, J, Steigemann, W, Singh, T.P, Bartunik, H, Bode, W, Huber, R. | 登録日 | 1981-10-26 | 公開日 | 1982-03-04 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography Acta Crystallogr.,Sect.B, 38, 1982
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1TGT
| ON THE DISORDERED ACTIVATION DOMAIN IN TRYPSINOGEN. CHEMICAL LABELLING AND LOW-TEMPERATURE CRYSTALLOGRAPHY | 分子名称: | CALCIUM ION, METHANOL, TRYPSINOGEN | 著者 | Walter, J, Steigemann, W, Singh, T.P, Bartunik, H, Bode, W, Huber, R. | 登録日 | 1981-10-26 | 公開日 | 1982-03-04 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography Acta Crystallogr.,Sect.B, 38, 1982
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4F7S
| Crystal structure of human CDK8/CYCC in the DMG-in conformation | 分子名称: | 1,2-ETHANEDIOL, Cyclin-C, Cyclin-dependent kinase 8, ... | 著者 | Schneider, E.V, Boettcher, J, Huber, R, Maskos, K. | 登録日 | 2012-05-16 | 公開日 | 2013-05-01 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure-kinetic relationship study of CDK8/CycC specific compounds. Proc.Natl.Acad.Sci.USA, 110, 2013
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4F7J
| Crystal structure of human CDK8/CYCC in complex with compound 3 (1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-(2-hydroxyethyl)urea) | 分子名称: | 1,2-ETHANEDIOL, 1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-(2-hydroxyethyl)urea, Cyclin-C, ... | 著者 | Schneider, E.V, Boettcher, J, Huber, R, Maskos, K. | 登録日 | 2012-05-16 | 公開日 | 2013-05-01 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure-kinetic relationship study of CDK8/CycC specific compounds. Proc.Natl.Acad.Sci.USA, 110, 2013
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4F6U
| Crystal structure of human CDK8/CYCC in complex with compound 5 (1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-[3-(morpholin-4-yl)propyl]urea) | 分子名称: | 1,2-ETHANEDIOL, 1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-[3-(morpholin-4-yl)propyl]urea, Cyclin-C, ... | 著者 | Schneider, E.V, Boettcher, J, Huber, R, Maskos, K. | 登録日 | 2012-05-15 | 公開日 | 2013-05-01 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure-kinetic relationship study of CDK8/CycC specific compounds. Proc.Natl.Acad.Sci.USA, 110, 2013
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4F6W
| Crystal structure of human CDK8/CYCC in complex with compound 1 (N-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-4-[2-({[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]carbamoyl}amino)ethyl]piperazine-1-carboxamide) | 分子名称: | 1,2-ETHANEDIOL, Cyclin-C, Cyclin-dependent kinase 8, ... | 著者 | Schneider, E.V, Boettcher, J, Huber, R, Maskos, K. | 登録日 | 2012-05-15 | 公開日 | 2013-05-01 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Structure-kinetic relationship study of CDK8/CycC specific compounds. Proc.Natl.Acad.Sci.USA, 110, 2013
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4F7L
| Crystal structure of human CDK8/CYCC in complex with compound 2 (tert-butyl [3-({[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]carbamoyl}amino)propyl]carbamate) | 分子名称: | Cyclin-C, Cyclin-dependent kinase 8, tert-butyl [3-({[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]carbamoyl}amino)propyl]carbamate | 著者 | Schneider, E.V, Boettcher, J, Huber, R, Maskos, K. | 登録日 | 2012-05-16 | 公開日 | 2013-05-01 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure-kinetic relationship study of CDK8/CycC specific compounds. Proc.Natl.Acad.Sci.USA, 110, 2013
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4F7N
| Crystal structure of human CDK8/CYCC in complex with compound 11 (1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-(5-hydroxypentyl)urea) | 分子名称: | 1,2-ETHANEDIOL, 1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-(5-hydroxypentyl)urea, Cyclin-C, ... | 著者 | Schneider, E.V, Boettcher, J, Huber, R, Maskos, K. | 登録日 | 2012-05-16 | 公開日 | 2013-05-01 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structure-kinetic relationship study of CDK8/CycC specific compounds. Proc.Natl.Acad.Sci.USA, 110, 2013
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4F70
| Crystal structure of human CDK8/CYCC in complex with compound 4 (1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-[2-(morpholin-4-yl)ethyl]urea) | 分子名称: | 1,2-ETHANEDIOL, 1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-[2-(morpholin-4-yl)ethyl]urea, Cyclin-C, ... | 著者 | Schneider, E.V, Boettcher, J, Huber, R, Maskos, K. | 登録日 | 2012-05-15 | 公開日 | 2013-05-01 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure-kinetic relationship study of CDK8/CycC specific compounds. Proc.Natl.Acad.Sci.USA, 110, 2013
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4F6S
| Crystal structure of human CDK8/CYCC in complex with compound 7 (1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]urea) | 分子名称: | 1,2-ETHANEDIOL, 1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]urea, Cyclin-C, ... | 著者 | Schneider, E.V, Boettcher, J, Huber, R, Maskos, K. | 登録日 | 2012-05-15 | 公開日 | 2013-05-01 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure-kinetic relationship study of CDK8/CycC specific compounds. Proc.Natl.Acad.Sci.USA, 110, 2013
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1TFX
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4G6L
| Crystal structure of human CDK8/CYCC in the DMG-in conformation | 分子名称: | Cyclin-C, Cyclin-dependent kinase 8, FORMIC ACID | 著者 | Schneider, E.V, Blaesse, M, Huber, R, Maskos, K. | 登録日 | 2012-07-19 | 公開日 | 2013-05-01 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure-kinetic relationship study of CDK8/CycC specific compounds. Proc.Natl.Acad.Sci.USA, 110, 2013
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1VLB
| STRUCTURE REFINEMENT OF THE ALDEHYDE OXIDOREDUCTASE FROM DESULFOVIBRIO GIGAS AT 1.28 A | 分子名称: | (MOLYBDOPTERIN-CYTOSINE DINUCLEOTIDE-S,S)-DIOXO-AQUA-MOLYBDENUM(V), ALDEHYDE OXIDOREDUCTASE, CHLORIDE ION, ... | 著者 | Rebelo, J.M, Dias, J.M, Huber, R, Moura, J.J.G, Romao, M.J. | 登録日 | 2004-07-20 | 公開日 | 2004-07-27 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | 主引用文献 | Structure refinement of the aldehyde oxidoreductase from Desulfovibrio gigas (MOP) at 1.28 A J.Biol.Inorg.Chem., 6, 2001
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1CEW
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3NZW
| Crystal structure of the yeast 20S proteasome in complex with 2b | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Proteasome component C1, Proteasome component C11, ... | 著者 | Groll, M, Gallastegui, N, Marechal, X, Le Ravalec, V, Basse, N, Richy, N, Genin, E, Huber, R, Moroder, M, Vidal, V, Reboud-Ravaux, M. | 登録日 | 2010-07-17 | 公開日 | 2011-02-16 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | 20S proteasome inhibition: designing noncovalent linear peptide mimics of the natural product TMC-95A. Chemmedchem, 5, 2010
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