4G6L
Crystal structure of human CDK8/CYCC in the DMG-in conformation
Summary for 4G6L
| Entry DOI | 10.2210/pdb4g6l/pdb |
| Related | 4F7S |
| Descriptor | Cyclin-dependent kinase 8, Cyclin-C, FORMIC ACID, ... (4 entities in total) |
| Functional Keywords | protein kinase complex, proteros, transferase-transcription complex, transferase/transcription |
| Biological source | Homo sapiens (human) More |
| Cellular location | Nucleus : P49336 P24863 |
| Total number of polymer chains | 2 |
| Total formula weight | 80746.95 |
| Authors | Schneider, E.V.,Blaesse, M.,Huber, R.,Maskos, K. (deposition date: 2012-07-19, release date: 2013-05-01, Last modification date: 2023-09-13) |
| Primary citation | Schneider, E.V.,Bottcher, J.,Huber, R.,Maskos, K.,Neumann, L. Structure-kinetic relationship study of CDK8/CycC specific compounds. Proc.Natl.Acad.Sci.USA, 110:8081-8086, 2013 Cited by PubMed: 23630251DOI: 10.1073/pnas.1305378110 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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