6KG3
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7YDL
| Crystal structure of the P450 BM3 heme domain mutant F87A/T268I/A184V/A82T in complex with N-imidazolyl-hexanoyl-L-phenylalanine | 分子名称: | (2S)-2-(6-imidazol-1-ylhexanoylamino)-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Dong, S, Chen, J, Jiang, Y, Cong, Z, Feng, Y. | 登録日 | 2022-07-04 | 公開日 | 2023-07-12 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Crystal structure of the P450 BM3 heme domain mutant F87A/T268I/A184V/A82T in complex with N-imidazolyl-hexanoyl-L-phenylalanine To Be Published
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4WVX
| Crystal structure of a phosphotriesterase-like lactonase Gkap in native form | 分子名称: | 1,2-ETHANEDIOL, COBALT (II) ION, Phosphotriesterase | 著者 | An, J, Zhang, Y, Yang, G.Y, Feng, Y. | 登録日 | 2014-11-07 | 公開日 | 2015-11-11 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Engineering a thermostable lactonase for enhanced phosphotriesterase activity against organophosphate pesticides To Be Published
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6DVB
| Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 5nt spacer | 分子名称: | DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | 登録日 | 2018-06-23 | 公開日 | 2019-02-20 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Structural basis of ECF-sigma-factor-dependent transcription initiation. Nat Commun, 10, 2019
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6DV9
| Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 4nt spacer | 分子名称: | DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | 登録日 | 2018-06-23 | 公開日 | 2019-02-20 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Structural basis of ECF-sigma-factor-dependent transcription initiation. Nat Commun, 10, 2019
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6DVE
| Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF selenomethionine-labelled sigma factor L) with 6 nt spacer | 分子名称: | DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*T)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*GP*AP*GP*TP*AP*AP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | 登録日 | 2018-06-23 | 公開日 | 2019-02-20 | 最終更新日 | 2019-02-27 | 実験手法 | X-RAY DIFFRACTION (3.812 Å) | 主引用文献 | Structural basis of ECF-sigma-factor-dependent transcription initiation. Nat Commun, 10, 2019
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2MDT
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8JYU
| Acyl-ACP Synthetase structure bound to Decanoyl-AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, Acyl-acyl carrier protein synthetase, DECANOIC ACID, ... | 著者 | Huang, H, Chang, S, Huang, M, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | 登録日 | 2023-07-03 | 公開日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.19 Å) | 主引用文献 | Acyl-ACP Synthetase structure bound to Decanoyl-AMP To Be Published
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8JYL
| Acyl-ACP Synthetase structure bound to C10-AMS | 分子名称: | Acyl-acyl carrier protein synthetase, MAGNESIUM ION, [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl N-decanoylsulfamate | 著者 | Huang, H, Chang, S, Huang, M, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | 登録日 | 2023-07-03 | 公開日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.33 Å) | 主引用文献 | Acyl-ACP Synthetase structure bound to C10-AMS To Be Published
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6DVD
| Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) with 6 nt spacer and bromine labelled in position "-11 | 分子名称: | DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*A)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | 登録日 | 2018-06-23 | 公開日 | 2019-02-20 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.899 Å) | 主引用文献 | Structural basis of ECF-sigma-factor-dependent transcription initiation. Nat Commun, 10, 2019
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3ELO
| Crystal Structure of Human Pancreatic Prophospholipase A2 | 分子名称: | Phospholipase A2, SULFATE ION | 著者 | Xu, W, Yi, L, Feng, Y, Chen, L, Liu, J. | 登録日 | 2008-09-22 | 公開日 | 2009-04-14 | 最終更新日 | 2014-02-05 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structural insight into the activation mechanism of human pancreatic prophospholipase A2 J.Biol.Chem., 284, 2009
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8FLM
| Cryo-EM structure of STING oligomer bound to cGAMP, NVS-STG2 and C53 | 分子名称: | 1-[(2-chloro-6-fluorophenyl)methyl]-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-2,3-dihydro-1H-indole-6-carboxamide, 4-({[4-(2-tert-butyl-5,5-dimethyl-1,3-dioxan-2-yl)phenyl]methyl}amino)-3-methoxybenzoic acid, Stimulator of interferon genes protein, ... | 著者 | Li, J, Canham, S.M, Zhang, X, Bai, X, Feng, Y. | 登録日 | 2022-12-21 | 公開日 | 2023-11-01 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Activation of human STING by a molecular glue-like compound. Nat.Chem.Biol., 20, 2024
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8FLK
| Cryo-EM structure of STING oligomer bound to cGAMP and NVS-STG2 | 分子名称: | 4-({[4-(2-tert-butyl-5,5-dimethyl-1,3-dioxan-2-yl)phenyl]methyl}amino)-3-methoxybenzoic acid, Stimulator of interferon genes protein, cGAMP | 著者 | Li, J, Canham, S.M, Zhang, X, Bai, X, Feng, Y. | 登録日 | 2022-12-21 | 公開日 | 2023-11-01 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Activation of human STING by a molecular glue-like compound. Nat.Chem.Biol., 20, 2024
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3GCG
| crystal structure of MAP and CDC42 complex | 分子名称: | Cell division control protein 42 homolog, L0028 (Mitochondria associated protein) | 著者 | Chai, J, Huang, Z, Feng, Y, Wu, X. | 登録日 | 2009-02-22 | 公開日 | 2009-07-21 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural insights into host GTPase isoform selection by a family of bacterial GEF mimics Nat.Struct.Mol.Biol., 16, 2009
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7Y0S
| Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-tyrosyl-L-tyrosine and hydroxylamine | 分子名称: | Bifunctional cytochrome P450/NADPH--P450 reductase, HYDROXYAMINE, I7X-TYR-TYR, ... | 著者 | Jiang, Y, Dong, S, Feng, Y, Cong, Z. | 登録日 | 2022-06-06 | 公開日 | 2023-06-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-tyrosyl-L-tyrosine and hydroxylamine To Be Published
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7Y0U
| Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-phenylalanyl-L-phenylalanine and hydroxylamine | 分子名称: | Bifunctional cytochrome P450/NADPH--P450 reductase, HYDROXYAMINE, I7X-PHE-PHE, ... | 著者 | Jiang, Y, Dong, S, Feng, Y, Cong, Z. | 登録日 | 2022-06-06 | 公開日 | 2023-06-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-phenylalanyl-L-phenylalanine and hydroxylamine To Be Published
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7Y0R
| Crystal structure of the P450 BM3 heme domain mutant F87L/V78S/A184V in complex with N-imidazolyl-hexanoyl-L-phenylalanine, p-toluidine and hydroxylamine | 分子名称: | (2S)-2-(6-imidazol-1-ylhexanoylamino)-3-phenyl-propanoic acid, 4-METHYLANILINE, Bifunctional cytochrome P450/NADPH--P450 reductase, ... | 著者 | Jiang, Y, Dong, S, Feng, Y, Cong, Z. | 登録日 | 2022-06-06 | 公開日 | 2023-06-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Crystal structure of the P450 BM3 heme domain mutant F87L/V78S/A184V in complex with N-imidazolyl-hexanoyl-L-phenylalanine, p-toluidine and hydroxylamine To Be Published
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7Y0Q
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7Y0P
| Crystal structure of the P450 BM3 heme domain mutant F87A/T268V/A82T/I263L in complex with N-imidazolyl-hexanoyl-L-phenylalanine, p-cresol and hydroxylamine | 分子名称: | (2S)-2-(6-imidazol-1-ylhexanoylamino)-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, HYDROXYAMINE, ... | 著者 | Jiang, Y, Dong, S, Feng, Y, Cong, Z. | 登録日 | 2022-06-06 | 公開日 | 2023-06-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Crystal structure of the P450 BM3 heme domain mutant F87A/T268V/A82T/I263L in complex with N-imidazolyl-hexanoyl-L-phenylalanine, p-cresol and hydroxylamine To Be Published
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7YJD
| Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-phenylalanine and hydroxylamine | 分子名称: | (2S)-2-(6-imidazol-1-ylhexanoylamino)-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, HYDROXYAMINE, ... | 著者 | Jiang, Y, Dong, S, Feng, Y, Cong, Z. | 登録日 | 2022-07-19 | 公開日 | 2023-07-26 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-phenylalanine and hydroxylamine To Be Published
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2M8V
| Solution Structure and Activity Study of Bovicin HJ50, a Particular Type AII Lantibiotic | 分子名称: | BovA | 著者 | Zhang, J, Feng, Y, Wang, J, Zhong, J. | 登録日 | 2013-05-29 | 公開日 | 2014-05-21 | 最終更新日 | 2024-07-10 | 実験手法 | SOLUTION NMR | 主引用文献 | Type AII lantibiotic bovicin HJ50 with a rare disulfide bond: structure, structure-activity relationships and mode of action. Biochem.J., 461, 2014
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5UHF
| Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with D-IX336 | 分子名称: | DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | 登録日 | 2017-01-11 | 公開日 | 2017-04-12 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (4.345 Å) | 主引用文献 | Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
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5UHA
| Crystal structure of Mycobacterium tuberculosis transcription initiation complex | 分子名称: | DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | 登録日 | 2017-01-11 | 公開日 | 2017-04-12 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.906 Å) | 主引用文献 | Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
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5UHG
| Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with D-AAP1 and Rifampin | 分子名称: | DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | 登録日 | 2017-01-11 | 公開日 | 2017-04-12 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (3.971 Å) | 主引用文献 | Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
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5UH6
| Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 2ntRNA in complex with Rifampin | 分子名称: | DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Lin, W, Das, K, Feng, Y, Ebright, R.H. | 登録日 | 2017-01-11 | 公開日 | 2017-04-12 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (3.837 Å) | 主引用文献 | Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
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