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8OYP
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BU of 8oyp by Molmil
Crystal structure of Ubiquitin specific protease 11 (USP11) in complex with a substrate mimetic
分子名称: CADMIUM ION, CHLORIDE ION, GLYCEROL, ...
著者Maurer, S.K, Caulton, S.G, Ward, S.J, Emsley, J, Dreveny, I.
登録日2023-05-05
公開日2023-10-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Ubiquitin-specific protease 11 structure in complex with an engineered substrate mimetic reveals a molecular feature for deubiquitination selectivity.
J.Biol.Chem., 299, 2023
6OVG
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BU of 6ovg by Molmil
L-Methionine Depletion with an Engineered Human Enzyme Disrupts Prostate Cancer Metabolism
分子名称: Cystathionine gamma-lyase, SULFATE ION
著者Yan, W, Irani, S, Zhang, J.
登録日2019-05-07
公開日2020-04-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.719 Å)
主引用文献Enzyme-mediated depletion of serum l-Met abrogates prostate cancer growth via multiple mechanisms without evidence of systemic toxicity.
Proc.Natl.Acad.Sci.USA, 117, 2020
6OHY
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BU of 6ohy by Molmil
Chimpanzee SIV Env trimeric ectodomain.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Pallesen, J, Andrabi, R, de Val, N, Burton, D.R, Ward, A.B.
登録日2019-04-08
公開日2019-06-05
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献The Chimpanzee SIV Envelope Trimer: Structure and Deployment as an HIV Vaccine Template.
Cell Rep, 27, 2019
6POP
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BU of 6pop by Molmil
Crystal structure of DauA in complex with NADP+
分子名称: 1,2-ETHANEDIOL, Aldehyde dehydrogenase, MAGNESIUM ION, ...
著者Pluvinage, B, Boraston, A.B.
登録日2019-07-04
公開日2019-10-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.147 Å)
主引用文献Insights into the kappa / iota-carrageenan metabolism pathway of some marinePseudoalteromonasspecies.
Commun Biol, 2, 2019
6PNU
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BU of 6pnu by Molmil
Crystal structure of native DauA
分子名称: 1,2-ETHANEDIOL, Aldehyde dehydrogenase
著者Pluvinage, B, Boraston, A.B.
登録日2019-07-03
公開日2019-10-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insights into the kappa / iota-carrageenan metabolism pathway of some marinePseudoalteromonasspecies.
Commun Biol, 2, 2019
6SJD
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BU of 6sjd by Molmil
ZC3H12B-ribonuclease domain bound to RNA
分子名称: CACODYLATE ION, MAGNESIUM ION, Probable ribonuclease ZC3H12B, ...
著者Morgunova, E, Bourenkov, G, Taipale, J.
登録日2019-08-13
公開日2020-07-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.29 Å)
主引用文献Binding specificities of human RNA-binding proteins toward structured and linear RNA sequences.
Genome Res., 30, 2020
4QUW
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BU of 4quw by Molmil
Crystal structure of the apo form of cyanobacterial aldehyde-deformylating oxygenase
分子名称: Aldehyde decarbonylase, HEXADECAN-1-OL
著者Jia, C.J, Li, M, Chang, W.R.
登録日2014-07-14
公開日2014-12-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structural insights into the catalytic mechanism of aldehyde-deformylating oxygenases.
Protein Cell, 6, 2015
8QYJ
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BU of 8qyj by Molmil
Human 20S proteasome assembly structure 1
分子名称: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome assembly chaperone 3, ...
著者Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
登録日2023-10-26
公開日2024-02-21
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
8QYM
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BU of 8qym by Molmil
Human 20S proteasome assembly intermediate structure 3
分子名称: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
著者Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
登録日2023-10-26
公開日2024-02-21
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
8QYS
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BU of 8qys by Molmil
Human preholo proteasome 20S core particle
分子名称: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
著者Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
登録日2023-10-26
公開日2024-02-21
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3.89 Å)
主引用文献Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
8QYO
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BU of 8qyo by Molmil
Human proteasome 20S core particle
分子名称: Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ...
著者Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
登録日2023-10-26
公開日2024-02-21
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.84 Å)
主引用文献Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
8QYN
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BU of 8qyn by Molmil
Human 20S proteasome assembly intermediate structure 5
分子名称: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
著者Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
登録日2023-10-26
公開日2024-02-21
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.88 Å)
主引用文献Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
8QZ9
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BU of 8qz9 by Molmil
Human 20S proteasome assembly intermediate structure 4
分子名称: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
著者Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
登録日2023-10-26
公開日2024-02-21
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
8QYL
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BU of 8qyl by Molmil
Human 20S proteasome assembly intermediate structure 2
分子名称: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ...
著者Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
登録日2023-10-26
公開日2024-02-21
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.67 Å)
主引用文献Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
6PTK
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BU of 6ptk by Molmil
Crystal structure of the sulfatase PsS1_NC C84A with bound sulfate ion
分子名称: 1,2-ETHANEDIOL, 3,6-anhydro-D-galactose, 4-O-sulfo-beta-D-galactopyranose, ...
著者Hettle, A.G, Boraston, A.B.
登録日2019-07-16
公開日2019-09-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Insights into the kappa / iota-carrageenan metabolism pathway of some marinePseudoalteromonasspecies.
Commun Biol, 2, 2019
4RC7
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BU of 4rc7 by Molmil
Crystal structure of cyanobacterial aldehyde-deformylating oxygenase F86YF87Y mutant
分子名称: Aldehyde decarbonylase, FE (II) ION, HEXADECAN-1-OL
著者Jia, C.J, Li, M, Chang, W.R.
登録日2014-09-14
公開日2014-12-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural insights into the catalytic mechanism of aldehyde-deformylating oxygenases.
Protein Cell, 6, 2015
1XHO
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BU of 1xho by Molmil
Chorismate mutase from Clostridium thermocellum Cth-682
分子名称: Chorismate mutase, UNKNOWN ATOM OR ION
著者Xu, H, Chen, L, Lee, D, Habel, J.E, Nguyen, J, Chang, S.-H, Kataeva, I, Chang, J, Zhao, M, Yang, H, Horanyi, P, Florence, Q, Tempel, W, Zhou, W, Lin, D, Zhang, H, Praissman, J, Arendall III, W.B, Richardson, J.S, Richardson, D.C, Ljungdahl, L, Liu, Z.-J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-09-20
公開日2004-11-23
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Away from the edge II: in-house Se-SAS phasing with chromium radiation.
Acta Crystallogr.,Sect.D, 61, 2005
7U5B
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BU of 7u5b by Molmil
Structure of Human KLK5 bound to anti-KLK5 Fab
分子名称: Kallikrein-5, SULFATE ION, anti-KLK5 Fab Heavy Chain, ...
著者Yin, J, Sudhamsu, J.
登録日2022-03-02
公開日2022-12-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.371 Å)
主引用文献Dual antibody inhibition of KLK5 and KLK7 for Netherton syndrome and atopic dermatitis.
Sci Transl Med, 14, 2022
4RC5
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BU of 4rc5 by Molmil
Crystal structure of cyanobacterial aldehyde-deformylating oxygenase
分子名称: Aldehyde decarbonylase, FE (II) ION, HEXADECAN-1-OL
著者Jia, C.J, Li, M, Chang, W.R.
登録日2014-09-14
公開日2014-12-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural insights into the catalytic mechanism of aldehyde-deformylating oxygenases.
Protein Cell, 6, 2015
6PT6
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BU of 6pt6 by Molmil
Crystal structure of PsS1_NC C84S in complex with i-neocarratetraose
分子名称: 3,6-anhydro-2-O-sulfo-alpha-D-galactopyranose-(1-3)-4-O-sulfo-beta-D-galactopyranose, CALCIUM ION, exo-2S-iota carrageenan S1 sulfatase
著者Hettle, A.G, Boraston, A.B.
登録日2019-07-15
公開日2019-09-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Insights into the kappa / iota-carrageenan metabolism pathway of some marinePseudoalteromonasspecies.
Commun Biol, 2, 2019
4RC8
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BU of 4rc8 by Molmil
Crystal structure of cyanobacterial aldehyde-deformylating oxygenase bound with fatty acid
分子名称: Aldehyde decarbonylase, FE (III) ION, STEARIC ACID
著者Jia, C.J, Li, M, Chang, W.R.
登録日2014-09-14
公開日2014-12-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Structural insights into the catalytic mechanism of aldehyde-deformylating oxygenases.
Protein Cell, 6, 2015
3Q32
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BU of 3q32 by Molmil
Structure of Janus kinase 2 with a pyrrolotriazine inhibitor
分子名称: 2-(2,6-difluoro-4-methoxyphenyl)-1-(4-{4-[(3-methyl-1H-pyrazol-5-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl}piperazin-1-yl)ethanone, Tyrosine-protein kinase JAK2
著者Sack, J.S.
登録日2010-12-21
公開日2011-02-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Pyrrolo[1,2-f]triazines as JAK2 inhibitors: Achieving potency and selectivity for JAK2 over JAK3.
Bioorg.Med.Chem.Lett., 21, 2011
3ENS
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BU of 3ens by Molmil
Crystal structure of human FXA in complex with methyl (2Z)-3-[(3-chloro-1H-indol-7-yl)amino]-2-cyano-3-{[(3S)-2-oxo-1-(2-oxo-2-pyrrolidin-1-ylethyl)azepan-3-yl]amino}acrylate
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, Activated factor Xa heavy chain, ...
著者Klei, H.E.
登録日2008-09-25
公開日2008-12-30
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Design, Structure-Activity Relationships, X-ray Crystal Structure, and Energetic Contributions of a Critical P1 Pharmacophore: 3-Chloroindole-7-yl-Based Factor Xa Inhibitors.
J.Med.Chem., 51, 2008
4MC5
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BU of 4mc5 by Molmil
Crystal structure of a subtype H18 hemagglutinin homologue from A/flat-faced bat/Peru/033/2010 (H18N11)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Yang, H, Carney, P.J, Chang, J.C, Guo, Z, Stevens, J.
登録日2013-08-21
公開日2013-10-23
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.238 Å)
主引用文献New world bats harbor diverse influenza a viruses.
Plos Pathog., 9, 2013
5ZX1
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BU of 5zx1 by Molmil
Crystal structure of ENT domain from T. brucei
分子名称: ENT
著者Shanhui, L, Xiaoming, T, Juan, M.
登録日2018-05-17
公開日2019-05-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Crystal structure of an ENT domain from Trypanosoma brucei.
Biochem.Biophys.Res.Commun., 505, 2018

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