6WYL
 
 | | Cryo-EM structure of GltPh L152C-G351C mutant in the intermediate outward-facing state. | | 分子名称: | ASPARTIC ACID, Glutamate transporter homolog | | 著者 | Font, J, Chen, I, Sobti, M, Stewart, A.G, Ryan, R.M. | | 登録日 | 2020-05-13 | | 公開日 | 2021-02-17 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Glutamate transporters have a chloride channel with two hydrophobic gates.
Nature, 591, 2021
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4UFQ
 | | Structure of a novel Hyaluronidase (Hyal_Sk) from Streptomyces koganeiensis. | | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Gavira, J.A, Messina, L, Pernagallo, S, Unciti-Broceta, J.D, Conejero-Muriel, M, Diaz-Mochon, J.J, Vaccaro, S, Caruso, S, Musumeci, L, Bisicchia, S, Di Pasquale, R. | | 登録日 | 2015-03-18 | | 公開日 | 2016-04-13 | | 最終更新日 | 2017-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Identification and Characterization of a Bacterial Hyaluronidase and its Production in Recombinant Form.
FEBS Lett., 590, 2016
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1RFL
 | | NMR data driven structural model of G-domain of MnmE protein | | 分子名称: | Probable tRNA modification GTPase trmE | | 著者 | Monleon, D, Esteve, V, Martinez-Vicente, M, Yim, L, Armengod, M.E, Celda, B. | | 登録日 | 2003-11-10 | | 公開日 | 2003-12-02 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural insights into the GTPase domain of Escherichia coli MnmE protein.
Proteins, 66, 2007
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6WYK
 | | Cryo-EM structure of the GltPh L152C-G321C mutant in the intermediate chloride conducting state. | | 分子名称: | ASPARTIC ACID, Glutamate transporter homolog | | 著者 | Font, J, Chen, I, Sobti, M, Stewart, A.G, Ryan, R.M. | | 登録日 | 2020-05-13 | | 公開日 | 2021-02-17 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Glutamate transporters have a chloride channel with two hydrophobic gates.
Nature, 591, 2021
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1RL1
 | | Solution structure of human Sgt1 CS domain | | 分子名称: | Suppressor of G2 allele of SKP1 homolog | | 著者 | Lee, Y.-T, Jacob, J, Michowski, W, Nowotny, M, Kuznicki, J, Chazin, W.J. | | 登録日 | 2003-11-24 | | 公開日 | 2004-05-04 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Human Sgt1 Binds HSP90 through the CHORD-Sgt1 Domain and Not the Tetratricopeptide Repeat Domain
J.Biol.Chem., 279, 2004
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1RHH
 | | Crystal Structure of the Broadly HIV-1 Neutralizing Fab X5 at 1.90 Angstrom Resolution | | 分子名称: | Fab X5, heavy chain, light chain | | 著者 | Darbha, R, Phogat, S, Labrijn, A.F, Shu, Y, Gu, Y, Andrykovitch, M, Zhang, M.Y, Pantophlet, R, Martin, L, Vita, C, Burton, D.R, Dimitrov, D.S, Ji, X. | | 登録日 | 2003-11-14 | | 公開日 | 2004-02-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal Structure of the Broadly Cross-Reactive HIV-1-Neutralizing Fab X5 and Fine Mapping of Its Epitope
Biochemistry, 43, 2004
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2AMP
 | | Crystal Structure Of Porcine Transmissible Gastroenteritis Virus Mpro in Complex with an Inhibitor N1 | | 分子名称: | 3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]-L-ALANYL-L-VALYL-N~1~-((1S)-4-ETHOXY-4-OXO-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE | | 著者 | Yang, H, Xue, X, Yang, K, Zhao, Q, Bartlam, M, Rao, Z. | | 登録日 | 2005-08-10 | | 公開日 | 2005-09-13 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
Plos Biol., 3, 2005
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1RNJ
 | | Crystal structure of inactive mutant dUTPase complexed with substrate analogue imido-dUTP | | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... | | 著者 | Barabas, O, Pongracz, V, Kovari, J, Wilmanns, M, Vertessy, B.G. | | 登録日 | 2003-12-01 | | 公開日 | 2004-09-07 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural Insights into the Catalytic Mechanism of Phosphate Ester Hydrolysis by dUTPase.
J.Biol.Chem., 279, 2004
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1RO8
 | | Structural analysis of the sialyltransferase CstII from Campylobacter jejuni in complex with a substrate analogue, cytidine-5'-monophosphate | | 分子名称: | CYTIDINE-5'-MONOPHOSPHATE, alpha-2,3/8-sialyltransferase | | 著者 | Chiu, C.P, Watts, A.G, Lairson, L.L, Gilbert, M, Lim, D, Wakarchuk, W.W, Withers, S.G, Strynadka, N.C. | | 登録日 | 2003-12-01 | | 公開日 | 2004-02-03 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural analysis of the sialyltransferase CstII from Campylobacter jejuni in complex with a substrate analog.
Nat.Struct.Mol.Biol., 11, 2004
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4UOW
 | | Crystal structure of the titin M10-Obscurin Ig domain 1 complex | | 分子名称: | CHLORIDE ION, Obscurin, SODIUM ION, ... | | 著者 | Pernigo, S, Fukuzawa, A, Gautel, M, Steiner, R.A. | | 登録日 | 2014-06-10 | | 公開日 | 2014-12-17 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | The Crystal Structure of the Human Titin:Obscurin Complex Reveals a Conserved Yet Specific Muscle M-Band Zipper Module.
J.Mol.Biol., 427, 2015
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1RJL
 | | Structure of the complex between OspB-CT and bactericidal Fab-H6831 | | 分子名称: | Fab H6831 H-chain, Fab H6831 L-chain, Outer surface protein B | | 著者 | Becker, M, Bunikis, J, Lade, B.D, Dunn, J.J, Barbour, A.G, Lawson, C.L. | | 登録日 | 2003-11-19 | | 公開日 | 2004-11-30 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural Investigation of Borrelia burgdorferi OspB, a BactericidalFab Target.
J.Biol.Chem., 280, 2005
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1ROP
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2AQU
 | | Structure of HIV-1 protease bound to atazanavir | | 分子名称: | (3S,8S,9S,12S)-3,12-BIS(1,1-DIMETHYLETHYL)-8-HYDROXY-4,11-DIOXO-9-(PHENYLMETHYL)-6-[[4-(2-PYRIDINYL)PHENYL]METHYL]-2,5, 6,10,13-PENTAAZATETRADECANEDIOIC ACID DIMETHYL ESTER, HIV-1 Protease | | 著者 | Clemente, J.C, Coman, R.M, Thiaville, M.M, Janka, L.K, Jeung, J.A, Nukoolkarn, S, Govindasamy, L, Agbandje-McKenna, M, McKenna, R, Leelamanit, W, Goodenow, M.M, Dunn, B.M. | | 登録日 | 2005-08-18 | | 公開日 | 2006-08-29 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Analysis of HIV-1 CRF_01 A/E protease inhibitor resistance: structural determinants for maintaining sensitivity and developing resistance to atazanavir.
Biochemistry, 45, 2006
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1RKI
 | | Structure of pag5_736 from P. aerophilum with three disulphide bonds | | 分子名称: | ACETATE ION, CHLORIDE ION, HEXAETHYLENE GLYCOL, ... | | 著者 | Beeby, M, Ryttersgaard, C, Boutz, D.R, Perry, L.J, Yeates, T.O. | | 登録日 | 2003-11-21 | | 公開日 | 2005-01-18 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The Genomics of Disulfide Bonding and Protein Stabilization in Thermophiles.
Plos Biol., 3, 2005
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2AUJ
 | | Structure of Thermus aquaticus RNA polymerase beta'-subunit insert | | 分子名称: | DNA-directed RNA polymerase beta' chain | | 著者 | Chlenov, M, Masuda, S, Murakami, K.S, Nikiforov, V, Darst, S.A, Mustaev, A. | | 登録日 | 2005-08-27 | | 公開日 | 2005-10-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure and Function of Lineage-specific Sequence Insertions in the Bacterial RNA Polymerase beta' Subunit
J.Mol.Biol., 353, 2005
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2AUV
 | | Solution Structure of HndAc : A Thioredoxin-like [2Fe-2S] Ferredoxin Involved in the NADP-reducing Hydrogenase Complex | | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, potential NAD-reducing hydrogenase subunit | | 著者 | Nouailler, M, Morelli, X, Bornet, O, Chetrit, B, Dermoun, Z, Guerlesquin, F. | | 登録日 | 2005-08-29 | | 公開日 | 2006-06-27 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of HndAc: a thioredoxin-like domain involved in the NADP-reducing hydrogenase complex
Protein Sci., 15, 2006
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1R17
 | | Crystal Structure Analysis of S.epidermidis adhesin SdrG binding to Fibrinogen (adhesin-ligand complex) | | 分子名称: | CALCIUM ION, fibrinogen-binding protein SdrG, fibrinopeptide B | | 著者 | Ponnuraj, K, Bowden, M.G, Davis, S, Gurusiddappa, S, Moore, D, Choe, D, Xu, Y, Hook, M, Narayana, S.V.L. | | 登録日 | 2003-09-23 | | 公開日 | 2003-10-28 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | A "dock, lock and latch" Structural Model for a Staphylococcal Adhesin Binding to Fibrinogen
Cell(Cambridge,Mass.), 115, 2003
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2AWU
 | | Synapse associated protein 97 PDZ2 domain variant C378G | | 分子名称: | AHH, Synapse-associated protein 97 | | 著者 | Von Ossowski, I, Oksanen, E, Von Ossowski, L, Cai, C, Sundberg, M, Goldman, A, Keinanen, K. | | 登録日 | 2005-09-02 | | 公開日 | 2006-08-29 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Crystal structure of the second PDZ domain of SAP97 in complex with a GluR-A C-terminal peptide
Febs J., 273, 2006
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2AZW
 | | Crystal structure of the MutT/nudix family protein from Enterococcus faecalis | | 分子名称: | MutT/nudix family protein, PENTAETHYLENE GLYCOL | | 著者 | Zhang, R, Zhou, M, Moy, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2005-09-12 | | 公開日 | 2006-01-10 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The 1.9A crystal structure of the MutT/nudix family protein from Enterococcus faecalis
To be Published
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6WH0
 | | Crystal structure of HyBcl-2-4 with HyBax BH3 | | 分子名称: | Apoptosis regulator BAX, Maltodextrin-binding protein,Bcl-2-like 4, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | 著者 | Kvansakul, M, Hinds, M.G, Banjara, S. | | 登録日 | 2020-04-07 | | 公開日 | 2021-03-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | The structural basis of Bcl-2 mediated cell death regulation in hydra.
Biochem.J., 477, 2020
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1R3U
 | | Crystal Structure of Hypoxanthine-Guanine Phosphoribosyltransferase from Thermoanaerobacter tengcongensis | | 分子名称: | ACETATE ION, Hypoxanthine-guanine phosphoribosyltransferase, MAGNESIUM ION | | 著者 | Chen, Q, Liang, Y.H, Gu, X.C, Luo, M, Su, X.D. | | 登録日 | 2003-10-03 | | 公開日 | 2004-10-19 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structure of Hypoxanthine-Guanine Phosphoribosyltransferase from Thermoanaerobacter tengcongensis
To be published
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6WO6
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4UMX
 | | IDH1 R132H in complex with cpd 1 | | 分子名称: | 2,6-bis(1H-imidazol-1-ylmethyl)-4-(2,4,4-trimethylpentan-2-yl)phenol, GLYCEROL, ISOCITRATE DEHYDROGENASE [NADP] CYTOPLASMIC, ... | | 著者 | Mathieu, M, Marquette, J.P. | | 登録日 | 2014-05-22 | | 公開日 | 2014-11-19 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Selective Inhibition of Mutant Isocitrate Dehydrogenase 1 (Idh1) Via Disruption of a Metal Binding Network by an Allosteric Small Molecule.
J.Biol.Chem., 290, 2015
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2B43
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2B6A
 | | Crystal structure of HIV-1 reverse transcriptase (RT) in complex with THR-50 | | 分子名称: | 1-(2,6-DIFLUOROBENZYL)-2-(2,6-DIFLUOROPHENYL)-4-METHYL-1H-BENZIMIDAZOLE, Reverse transcriptase p51 subunit, Reverse transcriptase p66 subunit | | 著者 | Morningstar, M.L, Roth, T, Smith, M.K, Zajac, M, Watson, K, Buckheit, R.W, Das, K, Zhang, W, Arnold, E, Michejda, C.J. | | 登録日 | 2005-09-30 | | 公開日 | 2005-11-01 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Crystal structure of HIV-1 reverse transcriptase (RT) in complex with THR-50
TO BE PUBLISHED
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