5COD
 
 | | Bovine heart complex I membrane domain | | 分子名称: | NADH-ubiquinone oxidoreductase chain 4, NADH-ubiquinone oxidoreductase chain 5, SDAP, ... | | 著者 | Zhu, J, Hirst, J, King, M.S, Yu, M, Leslie, A.G.W, Klipcan, L. | | 登録日 | 2015-07-20 | | 公開日 | 2015-09-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (6.74 Å) | | 主引用文献 | Structure of subcomplex I beta of mammalian respiratory complex I leads to new supernumerary subunit assignments.
Proc.Natl.Acad.Sci.USA, 112, 2015
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5DN6
 | | ATP synthase from Paracoccus denitrificans | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F0 subcomplex C subunit, ... | | 著者 | Morales-Rios, E, Montgomery, M.G, Leslie, A.G.W, Walker, J.E. | | 登録日 | 2015-09-09 | | 公開日 | 2015-10-28 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.98 Å) | | 主引用文献 | Structure of ATP synthase from Paracoccus denitrificans determined by X-ray crystallography at 4.0 angstrom resolution.
Proc.Natl.Acad.Sci.USA, 112, 2015
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7PDU
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6ET4
 | | HUMAN DIHYDROOROTATE DEHYDROGENASE IN COMPLEX WITH NOVEL INHIBITOR | | 分子名称: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, ACETIC ACID, CHLORIDE ION, ... | | 著者 | Hakansson, M, Walse, B, Gustavsson, A.-L, Lain, S. | | 登録日 | 2017-10-25 | | 公開日 | 2018-03-28 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.
Nat Commun, 9, 2018
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6FDB
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7QYF
 | | Structure of the transaminase PluriZyme variant (TR2E2) | | 分子名称: | Aminotransferase TR2 | | 著者 | Roda, S, Fernandez-Lopez, L, Benedens, M, Bollinger, A, Thies, S, Schumacher, J, Coscolin, C, Kazemi, M, Santiago, G, Gertzen, C.G, Gonzalez-Alfonso, J, Plou, F.J, Jaeger, K.E, Smits, S.H, Ferrer, M, Guallar, V. | | 登録日 | 2022-01-28 | | 公開日 | 2023-07-26 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | A Plurizyme with Transaminase and Hydrolase Activity Catalyzes Cascade Reactions.
Angew Chem Int Ed Engl, 61, 2022
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7QX3
 | | Structure of the transaminase TR2E2 with EOS | | 分子名称: | 2-azanylethyl hydrogen sulfate, Aminotransferase TR2 | | 著者 | Roda, S, Fernandez-Lopez, L, Benedens, M, Bollinger, A, Thies, S, Schumacher, J, Coscolin, C, Kazemi, M, Santiago, G, Gertzen, C.G, Gonzalez-Alfonso, J, Plou, F.J, Jaeger, K.E, Smits, S.H, Ferrer, M, Guallar, V. | | 登録日 | 2022-01-26 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | A Plurizyme with Transaminase and Hydrolase Activity Catalyzes Cascade Reactions.
Angew.Chem.Int.Ed.Engl., 61, 2022
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7QX0
 | | Transaminase Structure of Plurienzyme (Tr2E2) in complex with PLP | | 分子名称: | Aminotransferase TR2, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Roda, S, Fernandez-Lopez, L, Benedens, M, Bollinger, A, Thies, S, Schumacher, J, Coscolin, C, Kazemi, M, Santiago, G, Gertzen, C.G, Gonzalez-Alfonso, J, Plou, F.J, Jaeger, K.E, Smits, S.H, Ferrer, M, Guallar, V. | | 登録日 | 2022-01-26 | | 公開日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | A Plurizyme with Transaminase and Hydrolase Activity Catalyzes Cascade Reactions.
Angew Chem Int Ed Engl, 61, 2022
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7QYG
 | | Structure of the transaminase TR2 | | 分子名称: | Aminotransferase TR2 | | 著者 | Roda, S, Fernandez-Lopez, L, Benedens, M, Bollinger, A, Thies, S, Schumacher, J, Coscolin, C, Kazemi, M, Santiago, G, Gertzen, C.G, Gonzalez-Alfonso, J, Plou, F.J, Jaeger, K.E, Smits, S.H, Ferrer, M, Guallar, V. | | 登録日 | 2022-01-28 | | 公開日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | A Plurizyme with Transaminase and Hydrolase Activity Catalyzes Cascade Reactions.
Angew Chem Int Ed Engl, 61, 2022
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7PCZ
 | | Functional and structural characterization of redox sensitive superfolder green fluorescent protein and variants | | 分子名称: | ETHANOL, GLYCEROL, Green fluorescent protein | | 著者 | Fritz-Wolf, K, Heimsch, K.C, Schuh, A.K, Becker, K. | | 登録日 | 2021-08-04 | | 公開日 | 2022-02-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Structure and Function of Redox-Sensitive Superfolder Green Fluorescent Protein Variant.
Antioxid.Redox Signal., 37, 2022
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7PCA
 | | Functional and structural characterization of redox sensitive superfolder green fluorescent protein and variants | | 分子名称: | ETHANOL, FORMAMIDE, GLYCEROL, ... | | 著者 | Fritz-Wolf, K, Heimsch, K.C, Schuh, A.K, Becker, K. | | 登録日 | 2021-08-03 | | 公開日 | 2022-02-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Structure and Function of Redox-Sensitive Superfolder Green Fluorescent Protein Variant.
Antioxid.Redox Signal., 37, 2022
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7PD0
 | | Functional and structural characterization of redox sensitive superfolder green fluorescent protein and variants | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Green fluorescent protein, ... | | 著者 | Fritz-Wolf, K, Heimsch, K.C, Schuh, A.K, Becker, K. | | 登録日 | 2021-08-04 | | 公開日 | 2022-02-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure and Function of Redox-Sensitive Superfolder Green Fluorescent Protein Variant.
Antioxid.Redox Signal., 37, 2022
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6R2S
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6HRG
 | | Structure of Igni18, a novel metallo hydrolase from the hyperthermophilic archaeon Ignicoccus hospitalis KIN4/I | | 分子名称: | PHOSPHATE ION, POTASSIUM ION, UPF0173 metal-dependent hydrolase Igni_1254, ... | | 著者 | Smits, S.H, Streit, W.R, Jaeger, K.E, Hoeppner, A. | | 登録日 | 2018-09-26 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | A promiscuous ancestral enzyme ́s structure unveils protein variable regions of the highly diverse metallo-beta-lactamase family.
Commun Biol, 4, 2021
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2YCZ
 | | TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND ANTAGONIST IODOCYANOPINDOLOL | | 分子名称: | 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3-iodo-1H-indole-2-carbonitrile, BETA-1 ADRENERGIC RECEPTOR, octyl 1-thio-beta-D-glucopyranoside | | 著者 | Moukhametzianov, R, Warne, T, Edwards, P.C, Serrano-Vega, M.J, Leslie, A.G.W, Tate, C.G, Schertler, G.F.X. | | 登録日 | 2011-03-17 | | 公開日 | 2011-06-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | | 主引用文献 | Two Distinct Conformations of Helix 6 Observed in Antagonist-Bound Structures of a {Beta}1- Adrenergic Receptor.
Proc.Natl.Acad.Sci.USA, 108, 2011
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1IMV
 | | 2.85 A crystal structure of PEDF | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PIGMENT EPITHELIUM-DERIVED FACTOR | | 著者 | Simonovic, M, Gettins, P.G.W, Volz, K. | | 登録日 | 2001-05-11 | | 公開日 | 2001-09-26 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Crystal structure of human PEDF, a potent anti-angiogenic and neurite growth-promoting factor.
Proc.Natl.Acad.Sci.USA, 98, 2001
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2YCW
 | | TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND ANTAGONIST CARAZOLOL | | 分子名称: | (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol, BETA-1 ADRENERGIC RECEPTOR, HEGA-10, ... | | 著者 | Moukhametzianov, R, Warne, T, Edwards, P.C, Serrano-Vega, M.J, Leslie, A.G.W, Tate, C.G, Schertler, G.F.X. | | 登録日 | 2011-03-17 | | 公開日 | 2011-06-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Two Distinct Conformations of Helix 6 Observed in Antagonist-Bound Structures of a Beta-1- Adrenergic Receptor.
Proc.Natl.Acad.Sci.USA, 108, 2011
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4LIS
 | | Crystal Structure of UDP-galactose-4-epimerase from Aspergillus nidulans | | 分子名称: | GLYCEROL, IODIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Dalrymple, S.A, Ko, J, Sheoran, I, Kaminskyj, S.G.W, Sanders, D.A.R. | | 登録日 | 2013-07-03 | | 公開日 | 2013-10-23 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Elucidation of Substrate Specificity in Aspergillus nidulans UDP-Galactose-4-Epimerase.
Plos One, 8, 2013
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1K5W
 | | THREE-DIMENSIONAL STRUCTURE OF THE SYNAPTOTAGMIN 1 C2B-DOMAIN: SYNAPTOTAGMIN 1 AS A PHOSPHOLIPID BINDING MACHINE | | 分子名称: | CALCIUM ION, Synaptotagmin I | | 著者 | Fernandez, I, Arac, D, Ubach, J, Gerber, S.H, Shin, O, Gao, Y, Anderson, R.G.W, Sudhof, T.C, Rizo, J. | | 登録日 | 2001-10-12 | | 公開日 | 2002-01-23 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid binding machine.
Neuron, 32, 2001
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5HKK
 | | Caldalaklibacillus thermarum F1-ATPase (wild type) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | | 著者 | Ferguson, S.A, Cook, G.M, Montgomery, M.G, Leslie, A.G.W, Walker, J.E. | | 登録日 | 2016-01-14 | | 公開日 | 2016-09-21 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Regulation of the thermoalkaliphilic F1-ATPase from Caldalkalibacillus thermarum.
Proc.Natl.Acad.Sci.USA, 113, 2016
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3CVM
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1J8E
 | | Crystal structure of ligand-binding repeat CR7 from LRP | | 分子名称: | CALCIUM ION, LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1 | | 著者 | Simonovic, M, Dolmer, K, Huang, W, Strickland, D.K, Volz, K, Gettins, P.G.W. | | 登録日 | 2001-05-21 | | 公開日 | 2001-12-19 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Calcium coordination and pH dependence of the calcium affinity of ligand-binding repeat CR7 from the LRP. Comparison with related domains from the LRP and the LDL receptor.
Biochemistry, 40, 2001
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3AMV
 | | ALLOSTERIC INHIBITION OF GLYCOGEN PHOSPHORYLASE A BY A POTENTIAL ANTIDIABETIC DRUG | | 分子名称: | 2,3-DICARBOXY-4-(2-CHLORO-PHENYL)-1-ETHYL-5-ISOPROPOXYCARBONYL-6-METHYL-PYRIDINIUM, GLYCEROL, PROTEIN (GLYCOGEN PHOSPHORYLASE), ... | | 著者 | Oikonomakos, N.G, Tsitsanou, K.E, Zographos, S.E, Skamnaki, V.T. | | 登録日 | 1999-02-18 | | 公開日 | 1999-02-26 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Allosteric inhibition of glycogen phosphorylase a by the potential antidiabetic drug 3-isopropyl 4-(2-chlorophenyl)-1,4-dihydro-1-ethyl-2-methyl-pyridine-3,5,6-tricarbo xylate.
Protein Sci., 8, 1999
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1JRF
 | | NMR Solution Structure of the Viral Receptor Domain of Tva | | 分子名称: | CALCIUM ION, SUBGROUP A ROUS SARCOMA VIRUS RECEPTORS PG800 AND PG950 | | 著者 | Wang, Q.-Y, Huang, W, Dolmer, K, Gettins, P.G.W, Rong, L. | | 登録日 | 2001-08-13 | | 公開日 | 2002-03-08 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the viral receptor domain of Tva and its implications in viral entry.
J.Virol., 76, 2002
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1NBM
 | | THE STRUCTURE OF BOVINE F1-ATPASE COVALENTLY INHIBITED WITH 4-CHLORO-7-NITROBENZOFURAZAN | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, F1-ATPASE, ... | | 著者 | Orriss, G.L, Leslie, A.G.W, Braig, K, Walker, J.E. | | 登録日 | 1998-04-30 | | 公開日 | 1998-08-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Bovine F1-ATPase covalently inhibited with 4-chloro-7-nitrobenzofurazan: the structure provides further support for a rotary catalytic mechanism.
Structure, 6, 1998
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