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1GZ3
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BU of 1gz3 by Molmil
Molecular mechanism for the regulation of human mitochondrial NAD(P)+-dependent malic enzyme by ATP and fumarate
分子名称: ADENOSINE-5'-TRIPHOSPHATE, FUMARIC ACID, MANGANESE (II) ION, ...
著者Yang, Z, Lanks, C.W, Tong, L.
登録日2002-05-14
公開日2003-05-22
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular Mechanism for the Regulation of Human Mitochondrial Nad(P)+-Dependent Malic Enzyme by ATP and Fumarate
Structure, 10, 2002
6O3X
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BU of 6o3x by Molmil
Crystal structure of yeast Nrd1 CID in complex with Sen1 NIM2
分子名称: CHLORIDE ION, Helicase SEN1, Protein NRD1
著者Zhang, Y, Tong, L.
登録日2019-02-27
公開日2019-06-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.994 Å)
主引用文献Identification of Three Sequence Motifs in the Transcription Termination Factor Sen1 that Mediate Direct Interactions with Nrd1.
Structure, 27, 2019
1GTD
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BU of 1gtd by Molmil
NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG ID TT50) STRUCTURE OF MTH169, THE PURS SUBUNIT OF FGAM SYNTHETASE
分子名称: MTH169
著者Batra, R, Christendat, D, Saxild, H.H, Arrowsmith, C, Tong, L.
登録日2002-01-14
公開日2002-12-12
最終更新日2019-08-21
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Crystal Structure of Mth169, a Crucial Component of Phosphoribosylformylglycinamidine Synthetase
Proteins: Struct.,Funct., Genet., 49, 2002
7ZZ3
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BU of 7zz3 by Molmil
Cryo-EM structure of "BC react" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA
分子名称: ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
登録日2022-05-25
公開日2022-10-12
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.41 Å)
主引用文献CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7ZZ5
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BU of 7zz5 by Molmil
Cryo-EM structure of "BC open" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA
分子名称: ACETYL COENZYME *A, BICARBONATE ION, Pyruvate carboxylase
著者Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
登録日2022-05-25
公開日2022-10-12
最終更新日2022-10-26
実験手法ELECTRON MICROSCOPY (2.43 Å)
主引用文献CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7ZYZ
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BU of 7zyz by Molmil
Cryo-EM structure of "CT oxa" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA
分子名称: MANGANESE (II) ION, OXALOACETATE ION, Pyruvate carboxylase
著者Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
登録日2022-05-25
公開日2022-10-12
最終更新日2022-11-02
実験手法ELECTRON MICROSCOPY (2.47 Å)
主引用文献CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7ZZ8
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BU of 7zz8 by Molmil
Cryo-EM structure of Lactococcus lactis pyruvate carboxylase with acetyl-CoA and cyclic di-AMP
分子名称: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ...
著者Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
登録日2022-05-25
公開日2022-10-12
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7ZZ1
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BU of 7zz1 by Molmil
Cryo-EM structure of "CT react" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA
分子名称: BIOTIN, MAGNESIUM ION, MANGANESE (II) ION, ...
著者Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
登録日2022-05-25
公開日2022-10-12
最終更新日2022-11-02
実験手法ELECTRON MICROSCOPY (2.27 Å)
主引用文献CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7ZZ2
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BU of 7zz2 by Molmil
Cryo-EM structure of "CT pyr" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA
分子名称: MAGNESIUM ION, MANGANESE (II) ION, PYRUVIC ACID, ...
著者Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
登録日2022-05-25
公開日2022-10-12
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.48 Å)
主引用文献CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7ZZ0
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BU of 7zz0 by Molmil
Cryo-EM structure of "CT empty" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA
分子名称: MAGNESIUM ION, MANGANESE (II) ION, Pyruvate carboxylase
著者Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
登録日2022-05-25
公開日2022-10-12
最終更新日2022-11-02
実験手法ELECTRON MICROSCOPY (2.26 Å)
主引用文献CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7ZZ4
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BU of 7zz4 by Molmil
Cryo-EM structure of "BC closed" conformation of Lactococcus lactis pyruvate carboxylase with acetyl-CoA
分子名称: ACETYL COENZYME *A, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
登録日2022-05-25
公開日2022-10-12
最終更新日2022-11-02
実験手法ELECTRON MICROSCOPY (2.63 Å)
主引用文献CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7ZYY
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BU of 7zyy by Molmil
Cryo-EM structure of Lactococcus lactis pyruvate carboxylase with acetyl-CoA
分子名称: ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, BICARBONATE ION, ...
著者Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
登録日2022-05-25
公開日2022-10-12
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.12 Å)
主引用文献CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
7ZZ6
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BU of 7zz6 by Molmil
Cryo-EM structure of "CT-CT dimer" of Lactococcus lactis pyruvate carboxylase with acetyl-CoA
分子名称: MAGNESIUM ION, MANGANESE (II) ION, PYRUVIC ACID, ...
著者Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M.
登録日2022-05-25
公開日2022-12-28
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.15 Å)
主引用文献CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase.
Nat Commun, 13, 2022
5HCU
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BU of 5hcu by Molmil
Crystal structure of mouse acetylchoinesterase inhibited by DFP
分子名称: Acetylcholinesterase
著者Tran, T.H, Tong, L.
登録日2016-01-04
公開日2016-01-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4151 Å)
主引用文献Discovery of New Classes of Compounds that Reactivate Acetylcholinesterase Inhibited by Organophosphates.
Chembiochem, 16, 2015
5DTI
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BU of 5dti by Molmil
Crystal structure of mouse acetylcholinesterase
分子名称: Acetylcholinesterase
著者Tran, T.H, Tong, L.
登録日2015-09-18
公開日2015-10-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献Discovery of New Classes of Compounds that Reactivate Acetylcholinesterase Inhibited by Organophosphates.
Chembiochem, 16, 2015
4RRP
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BU of 4rrp by Molmil
Crystal Structure of the Fab complexed with antigen Asf1p, Northeast Structural Genomics Consortium (NESG) Target PdR16
分子名称: Antigen Asf1p, DI(HYDROXYETHYL)ETHER, Fab antibody, ...
著者Kuzin, A, Lew, S, Seetharaman, J, Mao, L, Xiao, R, Oconnell, P.T, Maglaqui, M, Bailey, L, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Chaperone-Enabled Studies of Epigenetic Regulation Enzymes (CEBS), Northeast Structural Genomics Consortium (NESG)
登録日2014-11-06
公開日2014-12-31
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Crystal Structure of the Fab complexed with antigen Asf1p, Northeast Structural Genomics Consortium (NESG) Target PdR16
To be Published
6UN9
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BU of 6un9 by Molmil
Crystal Structure of the Q7VLF5_HAEDU protein from Haemophilus ducreyi. Northeast Structural Genomics Consortium Target Hdr25
分子名称: Uncharacterized protein
著者Vorobiev, S.M, Seetharaman, J, Kolev, M, Xiao, R, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2019-10-11
公開日2020-12-09
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of the Q7VLF5_HAEDU protein from Haemophilus ducreyi. Northeast Structural Genomics Consortium Target Hdr25
To Be Published
6URG
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BU of 6urg by Molmil
Cryo-EM structure of human CPSF160-WDR33-CPSF30-CPSF100 PIM complex
分子名称: Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 2, Cleavage and polyadenylation specificity factor subunit 4, ...
著者Sun, Y, Zhang, Y, Walz, T, Tong, L.
登録日2019-10-23
公開日2019-11-27
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural Insights into the Human Pre-mRNA 3'-End Processing Machinery.
Mol.Cell, 77, 2020
5IKL
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BU of 5ikl by Molmil
Crystal structure of P. aeruginosa geranyl-CoA carboxylase (GCC), beta subunit
分子名称: Geranyl-CoA carboxylase, beta-subunit
著者Huang, C.S, Jurado, A.R, Tong, L.
登録日2016-03-03
公開日2016-04-13
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure and substrate selectivity of the 750-kDa alpha6beta6 holoenzyme of geranyl-CoA carboxylase
Nat Commun, 6, 2015
6URO
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BU of 6uro by Molmil
Cryo-EM structure of human CPSF160-WDR33-CPSF30-PAS RNA-CstF77 complex
分子名称: Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, Cleavage stimulation factor subunit 3, ...
著者Sun, Y, Zhang, Y, Walz, T, Tong, L.
登録日2019-10-23
公開日2019-11-27
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural Insights into the Human Pre-mRNA 3'-End Processing Machinery.
Mol.Cell, 77, 2020
7KZ8
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BU of 7kz8 by Molmil
Crystal structure of substrate-binding protein Aapf from Pseudomonas sp. PDC86
分子名称: GLYCEROL, Peptide/nickel transport system substrate-binding protein AapF
著者Luo, S, Dadhwal, P, Tong, L.
登録日2020-12-10
公開日2021-03-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for a bacterial Pip system plant effector recognition protein.
Proc.Natl.Acad.Sci.USA, 118, 2021
7KZ9
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BU of 7kz9 by Molmil
Crystal structure of Pseudomonas sp. PDC86 substrate-binding protein Aapf in complex with a signaling molecule HEHEAA
分子名称: GLYCEROL, N,N~2~-bis(2-hydroxyethyl)glycinamide, Peptide/nickel transport system substrate-binding protein AapF, ...
著者Luo, S, Dadhwal, P, Tong, L.
登録日2020-12-10
公開日2021-03-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for a bacterial Pip system plant effector recognition protein.
Proc.Natl.Acad.Sci.USA, 118, 2021
6V4X
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BU of 6v4x by Molmil
Cryo-EM structure of an active human histone pre-mRNA 3'-end processing machinery at 3.2 Angstrom resolution
分子名称: Cleavage and polyadenylation specificity factor subunit 2, Cleavage and polyadenylation specificity factor subunit 3, Small nuclear ribonucleoprotein E, ...
著者Sun, Y, Zhang, Y, Walz, T, Tong, L.
登録日2019-12-02
公開日2020-02-19
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of an active human histone pre-mRNA 3'-end processing machinery.
Science, 367, 2020
6WUK
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BU of 6wuk by Molmil
Crystal structure of mouse DXO in complex with CoA
分子名称: COENZYME A, Decapping and exoribonuclease protein
著者Doamekpor, S.K, Tong, L.
登録日2020-05-04
公開日2020-05-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献DXO/Rai1 enzymes remove 5'-end FAD and dephospho-CoA caps on RNAs.
Nucleic Acids Res., 48, 2020
6WUG
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BU of 6wug by Molmil
Crystal Structure of S. pombe Rai1 in complex with 3'-FADP
分子名称: 1,2-ETHANEDIOL, Decapping nuclease din1, MAGNESIUM ION, ...
著者Doamekpor, S.K, Tong, L.
登録日2020-05-04
公開日2020-05-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献DXO/Rai1 enzymes remove 5'-end FAD and dephospho-CoA caps on RNAs.
Nucleic Acids Res., 48, 2020

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