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9DKA
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BU of 9dka by Molmil
Structure of URAT1 in complex with benzbromarone
分子名称: URAT1, [3,5-bis(bromanyl)-4-oxidanyl-phenyl]-(2-ethyl-1-benzofuran-3-yl)methanone
著者Suo, Y, Fedor, J.G, Lee, S.-Y.
登録日2024-09-08
公開日2025-06-18
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Molecular basis of the urate transporter URAT1 inhibition by gout drugs.
Nat Commun, 16, 2025
9DKC
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BU of 9dkc by Molmil
Structure of URAT1 in complex with TD-3
分子名称: 2-({1-[(4-bromonaphthalen-1-yl)methyl]-1H-imidazo[4,5-b]pyridin-2-yl}sulfanyl)-2-methylpropanoic acid, URAT1
著者Suo, Y, Fedor, J.G, Lee, S.-Y.
登録日2024-09-08
公開日2025-06-18
実験手法ELECTRON MICROSCOPY (2.55 Å)
主引用文献Molecular basis of the urate transporter URAT1 inhibition by gout drugs.
Nat Commun, 16, 2025
7TRL
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BU of 7trl by Molmil
Crystal structure of human BIRC2 BIR3 domain in complex with histone H3
分子名称: 1,2-ETHANEDIOL, Baculoviral IAP repeat-containing protein 2, Histone H3, ...
著者Klein, B.J, Tencer, A.H, Kutateladze, T.G.
登録日2022-01-29
公開日2023-08-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Molecular basis for nuclear accumulation and targeting of the inhibitor of apoptosis BIRC2.
Nat.Struct.Mol.Biol., 30, 2023
7TRM
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BU of 7trm by Molmil
Crystal structure of human BIRC2 BIR3 domain in complex with inhibitor LCL-161
分子名称: 1,2-ETHANEDIOL, Baculoviral IAP repeat-containing protein 2, LCL-161, ...
著者Tencer, A.H, Klein, B.J, Kutateladze, T.G.
登録日2022-01-29
公開日2023-08-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis for nuclear accumulation and targeting of the inhibitor of apoptosis BIRC2.
Nat.Struct.Mol.Biol., 30, 2023
7KN3
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BU of 7kn3 by Molmil
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain complexed with a pre-pandemic antibody S-B8 Fab
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, S-B8 Fab heavy chain, ...
著者Liu, H, Zhu, X, Wilson, I.A.
登録日2020-11-04
公開日2021-09-22
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.251 Å)
主引用文献Neutralizing Antibodies to SARS-CoV-2 Selected from a Human Antibody Library Constructed Decades Ago.
Adv Sci, 9, 2022
7KN4
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BU of 7kn4 by Molmil
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain complexed with a pre-pandemic antibody S-E6 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, S-E6 Fab heavy chain, S-E6 Fab light chain, ...
著者Liu, H, Wilson, I.A.
登録日2020-11-04
公開日2021-09-22
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Neutralizing Antibodies to SARS-CoV-2 Selected from a Human Antibody Library Constructed Decades Ago.
Adv Sci, 9, 2022
7YQQ
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BU of 7yqq by Molmil
Crystal Structure of Xcc NAMPT and its complex with NMN
分子名称: BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, PHOSPHATE ION, Pre-B cell enhancing factor related protein
著者Xu, G.L, Ming, Z.H.
登録日2022-08-08
公開日2024-02-14
最終更新日2024-09-04
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Structural insights into Xanthomonas campestris pv. campestris NAD + biosynthesis via the NAM salvage pathway.
Commun Biol, 7, 2024
7YQP
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BU of 7yqp by Molmil
Xcc Nicotinamide Phosphoribosyltransferase
分子名称: Pre-B cell enhancing factor related protein
著者Xu, G.L, Ming, Z.H.
登録日2022-08-08
公開日2024-02-14
最終更新日2024-09-04
実験手法X-RAY DIFFRACTION (2.088 Å)
主引用文献Structural insights into Xanthomonas campestris pv. campestris NAD + biosynthesis via the NAM salvage pathway.
Commun Biol, 7, 2024
7YQO
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BU of 7yqo by Molmil
Xcc Nicotinamide Phosphoribosyltransferase
分子名称: GLYCEROL, Pre-B cell enhancing factor related protein
著者Xu, G.L, Ming, Z.H.
登録日2022-08-08
公開日2024-02-14
最終更新日2024-09-04
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structural insights into Xanthomonas campestris pv. campestris NAD + biosynthesis via the NAM salvage pathway.
Commun Biol, 7, 2024
7YQR
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BU of 7yqr by Molmil
Crystal Structure of Xcc NAMPT and its complex with NAM
分子名称: NICOTINAMIDE, Pre-B cell enhancing factor related protein
著者Xu, G.L, Ming, Z.H.
登録日2022-08-08
公開日2024-02-14
最終更新日2024-09-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural insights into Xanthomonas campestris pv. campestris NAD + biosynthesis via the NAM salvage pathway.
Commun Biol, 7, 2024
4L72
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BU of 4l72 by Molmil
Crystal structure of MERS-CoV complexed with human DPP4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4, ...
著者Wang, X.Q, Wang, N.S.
登録日2013-06-13
公開日2013-08-21
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (3.005 Å)
主引用文献Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4
Cell Res., 23, 2013
3H0H
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BU of 3h0h by Molmil
human Fyn SH3 domain R96I mutant, crystal form I
分子名称: Proto-oncogene tyrosine-protein kinase Fyn, TETRAETHYLENE GLYCOL
著者Dumas, C, Strub, M.-P, Arold, S.T.
登録日2009-04-09
公開日2010-04-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Synergy and allostery in ligand binding by HIV-1 Nef.
Biochem.J., 478, 2021
3KQI
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BU of 3kqi by Molmil
crystal structure of PHF2 PHD domain complexed with H3K4Me3 peptide
分子名称: CHLORIDE ION, GLYCEROL, H3K4Me3 peptide, ...
著者Wen, H, Li, J.Z, Song, T, Lu, M, Lee, M.
登録日2009-11-17
公開日2010-02-02
最終更新日2025-03-26
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Recognition of histone H3K4 trimethylation by the plant homeodomain of PHF2 modulates histone demethylation.
J.Biol.Chem., 285, 2010
6E86
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BU of 6e86 by Molmil
Solution structure of ZZZ3 ZZ domain in complex with histone H3K4ac peptide
分子名称: H3K4ac, ZINC ION, ZZ-type zinc finger-containing protein 3
著者Zhang, Y, Kutateladze, T.G.
登録日2018-07-27
公開日2018-09-19
最終更新日2024-10-16
実験手法SOLUTION NMR
主引用文献The ZZ-type zinc finger of ZZZ3 modulates the ATAC complex-mediated histone acetylation and gene activation.
Nat Commun, 9, 2018
2PUY
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BU of 2puy by Molmil
Crystal Structure of the BHC80 PHD finger
分子名称: Histone H3, PHD finger protein 21A, ZINC ION
著者Horton, J.R, Cheng, X, Collins, R.E.
登録日2007-05-09
公開日2007-08-14
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression.
Nature, 448, 2007
3NMW
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BU of 3nmw by Molmil
Crystal structure of armadillo repeats domain of APC
分子名称: APC variant protein, SULFATE ION
著者Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G.
登録日2010-06-22
公開日2011-07-06
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis for the recognition of Asef by adenomatous polyposis coli.
Cell Res., 22, 2012
5BRR
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BU of 5brr by Molmil
Michaelis complex of tPA-S195A:PAI-1
分子名称: GLYCEROL, Plasminogen activator inhibitor 1, TRIETHYLENE GLYCOL, ...
著者Gong, L.
登録日2015-06-01
公開日2015-09-02
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (3.16 Å)
主引用文献Crystal Structure of the Michaelis Complex between Tissue-type Plasminogen Activator and Plasminogen Activators Inhibitor-1
J.Biol.Chem., 290, 2015
3H0F
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BU of 3h0f by Molmil
Crystal structure of the human Fyn SH3 R96W mutant
分子名称: 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, Proto-oncogene tyrosine-protein kinase Fyn
著者Ponchon, L, Hoh, F, Labesse, G, Dumas, C, Arold, S.T.
登録日2009-04-09
公開日2010-04-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Synergy and allostery in ligand binding by HIV-1 Nef.
Biochem.J., 478, 2021
3H0I
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BU of 3h0i by Molmil
human Fyn SH3 domain R96I mutant, crystal form II
分子名称: Proto-oncogene tyrosine-protein kinase Fyn
著者Dumas, C, Strub, M.-P, Arold, S.T.
登録日2009-04-09
公開日2010-04-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Synergy and allostery in ligand binding by HIV-1 Nef.
Biochem.J., 478, 2021
3NMZ
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BU of 3nmz by Molmil
Crystal structure of APC complexed with Asef
分子名称: APC variant protein, Rho guanine nucleotide exchange factor 4
著者Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G.
登録日2010-06-23
公開日2011-07-06
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Structural basis for the recognition of Asef by adenomatous polyposis coli.
Cell Res., 22, 2012
3NMX
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BU of 3nmx by Molmil
Crystal structure of APC complexed with Asef
分子名称: APC variant protein, Rho guanine nucleotide exchange factor 4
著者Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G.
登録日2010-06-22
公開日2011-07-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for the recognition of Asef by adenomatous polyposis coli.
Cell Res., 22, 2012
3O36
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BU of 3o36 by Molmil
Crystal structure of TRIM24 PHD-Bromo complexed with H4(14-19)K16ac peptide
分子名称: Histone H4, Transcription intermediary factor 1-alpha, ZINC ION
著者Wang, Z, Patel, D.J.
登録日2010-07-23
公開日2010-12-15
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献TRIM24 links a non-canonical histone signature to breast cancer.
Nature, 468, 2010
4TMP
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BU of 4tmp by Molmil
Crystal structure of AF9 YEATS bound to H3K9ac peptide
分子名称: 1,2-ETHANEDIOL, ALA-ARG-THR-LYS-GLN-THR-ALA-ARG-ALY-SER-THR, Protein AF-9
著者Li, H, Li, Y, Wang, H, Ren, Y.
登録日2014-06-02
公開日2014-11-05
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献AF9 YEATS Domain Links Histone Acetylation to DOT1L-Mediated H3K79 Methylation.
Cell, 159, 2014
8WZB
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BU of 8wzb by Molmil
RS head-neck monomer
分子名称: DPY30 domain containing 2, DnaJ homolog subfamily B member 13, Nucleoside diphosphate kinase homolog 5, ...
著者Meng, X, Cong, Y.
登録日2023-11-01
公開日2024-02-07
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献Multi-scale structures of the mammalian radial spoke and divergence of axonemal complexes in ependymal cilia.
Nat Commun, 15, 2024
8X2U
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BU of 8x2u by Molmil
Radial spoke head-neck dimer
分子名称: DPY30 domain containing 2, DnaJ homolog subfamily B member 13, Nucleoside diphosphate kinase homolog 5, ...
著者Meng, X, Cong, Y.
登録日2023-11-10
公開日2024-02-07
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献Multi-scale structures of the mammalian radial spoke and divergence of axonemal complexes in ependymal cilia.
Nat Commun, 15, 2024

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件を2025-07-09に公開中

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