1ZMX
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![BU of 1zmx by Molmil](/molmil-images/mine/1zmx) | Crystal structure of D. melanogaster deoxyribonucleoside kinase N64D mutant in complex with thymidine | 分子名称: | Deoxynucleoside kinase, SULFATE ION, THYMIDINE | 著者 | Welin, M, Skovgaard, T, Knecht, W, Berenstein, D, Munch-Petersen, B, Piskur, J, Eklund, H. | 登録日 | 2005-05-11 | 公開日 | 2005-05-24 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural basis for the changed substrate specificity of Drosophila melanogaster deoxyribonucleoside kinase mutant N64D. Febs J., 272, 2005
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1ZM7
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![BU of 1zm7 by Molmil](/molmil-images/mine/1zm7) | Crystal structure of D. melanogaster deoxyribonucleoside kinase mutant N64D in complex with dTTP | 分子名称: | Deoxynucleoside kinase, MAGNESIUM ION, THYMIDINE-5'-TRIPHOSPHATE | 著者 | Welin, M, Skovgaard, T, Knecht, W, Berenstein, D, Munch-Petersen, B, Piskur, J, Eklund, H. | 登録日 | 2005-05-10 | 公開日 | 2005-05-17 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis for the changed substrate specificity of Drosophila melanogaster deoxyribonucleoside kinase mutant N64D. Febs J., 272, 2005
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2WRS
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![BU of 2wrs by Molmil](/molmil-images/mine/2wrs) | Crystal Structure of the Mono-Zinc Metallo-beta-lactamase VIM-4 from Pseudomonas aeruginosa | 分子名称: | BETA-LACTAMASE VIM-4, CITRATE ANION, CITRIC ACID, ... | 著者 | Lassaux, P, Hamel, M, Gulea, M, Delbruck, H, Traore, D.A.K, Mercuri, P.S, Horsfall, L, Dehareng, D, Gaumont, A.-C, Frere, J.-M, Ferrer, J.-L, Hoffmann, K, Galleni, M, Bebrone, C. | 登録日 | 2009-09-02 | 公開日 | 2010-06-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Mercaptophosphonate Compounds as Broad-Spectrum Inhibitors of the Metallo-Beta-Lactamases. J.Med.Chem., 53, 2010
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1K76
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![BU of 1k76 by Molmil](/molmil-images/mine/1k76) | Solution Structure of the C-terminal Sem-5 SH3 Domain (Minimized Average Structure) | 分子名称: | SEX MUSCLE ABNORMAL PROTEIN 5 | 著者 | Ferreon, J, Volk, D, Luxon, B, Gorenstein, D, Hilser, V. | 登録日 | 2001-10-18 | 公開日 | 2003-05-20 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure, Dynamics and Thermodynamics of the Native State Ensemble
of Sem-5 C-Terminal SH3 Domain Biochemistry, 42, 2003
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3EBA
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![BU of 3eba by Molmil](/molmil-images/mine/3eba) | CAbHul6 FGLW mutant (humanized) in complex with human lysozyme | 分子名称: | CAbHul6, Lysozyme C, SULFATE ION | 著者 | Loris, R, Vincke, C, Saerens, D, Martinez-Rodriguez, S, Muyldermans, S, Conrath, K. | 登録日 | 2008-08-27 | 公開日 | 2008-12-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | General Strategy to Humanize a Camelid Single-domain Antibody and Identification of a Universal Humanized Nanobody Scaffold J.Biol.Chem., 284, 2009
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3EAK
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![BU of 3eak by Molmil](/molmil-images/mine/3eak) | NbBCII10 humanized (FGLA mutant) | 分子名称: | NbBCII10-FGLA, SULFATE ION | 著者 | Vincke, C, Loris, R, Saerens, D, Martinez-Rodriguez, S, Muyldermans, S, Conrath, K. | 登録日 | 2008-08-26 | 公開日 | 2008-12-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold. J.Biol.Chem., 2008
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3EUL
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![BU of 3eul by Molmil](/molmil-images/mine/3eul) | Structure of the signal receiver domain of the putative response regulator NarL from Mycobacterium tuberculosis | 分子名称: | CHLORIDE ION, POSSIBLE NITRATE/NITRITE RESPONSE TRANSCRIPTIONAL REGULATORY PROTEIN NARL (DNA-binding response regulator, LuxR family) | 著者 | Schneider, G, Schnell, R, Agren, D. | 登録日 | 2008-10-10 | 公開日 | 2008-11-11 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | 1.9 A structure of the signal receiver domain of the putative response regulator NarL from Mycobacterium tuberculosis. Acta Crystallogr.,Sect.F, 64, 2008
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1KFZ
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![BU of 1kfz by Molmil](/molmil-images/mine/1kfz) | Solution Structure of C-terminal Sem-5 SH3 Domain (Ensemble of 16 Structures) | 分子名称: | SEX MUSCLE ABNORMAL PROTEIN 5 | 著者 | Ferreon, J.C, Volk, D.E, Luxon, B.A, Gorenstein, D, Hilser, V.J. | 登録日 | 2001-11-24 | 公開日 | 2003-05-20 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure, Dynamics and Thermodynamics of the Native State Ensemble
of Sem-5 C-Terminal SH3 Domain Biochemistry, 42, 2003
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1J3G
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![BU of 1j3g by Molmil](/molmil-images/mine/1j3g) | Solution structure of Citrobacter Freundii AmpD | 分子名称: | AmpD protein, ZINC ION | 著者 | Liepinsh, E, Genereux, C, Dehareng, D, Joris, B, Otting, G. | 登録日 | 2003-01-31 | 公開日 | 2003-02-18 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Structure of Citrobacter freundii AmpD, Comparison with Bacteriophage T7 Lysozyme
and Homology with PGRP Domains J.Mol.Biol., 327, 2003
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1E3Y
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![BU of 1e3y by Molmil](/molmil-images/mine/1e3y) | |
1E41
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![BU of 1e41 by Molmil](/molmil-images/mine/1e41) | |
1CXR
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![BU of 1cxr by Molmil](/molmil-images/mine/1cxr) | |
2JZI
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![BU of 2jzi by Molmil](/molmil-images/mine/2jzi) | |
7V8N
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![BU of 7v8n by Molmil](/molmil-images/mine/7v8n) | |
1C54
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![BU of 1c54 by Molmil](/molmil-images/mine/1c54) | SOLUTION STRUCTURE OF RIBONUCLEASE SA | 分子名称: | RIBONUCLEASE SA | 著者 | Laurents, D.V, Canadillas-Perez, J.M, Santoro, J, Schell, D, Pace, C.N, Rico, M, Bruix, M. | 登録日 | 1999-10-22 | 公開日 | 2001-11-28 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure and dynamics of ribonuclease Sa. Proteins, 44, 2001
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2M0K
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![BU of 2m0k by Molmil](/molmil-images/mine/2m0k) | |
2M0J
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![BU of 2m0j by Molmil](/molmil-images/mine/2m0j) | |
2L4V
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![BU of 2l4v by Molmil](/molmil-images/mine/2l4v) | |
1BCG
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![BU of 1bcg by Molmil](/molmil-images/mine/1bcg) | SCORPION TOXIN BJXTR-IT | 分子名称: | TOXIN BJXTR-IT | 著者 | Oren, D, Froy, O, Amit, E, Kleinberger-Doron, N, Gurevitz, M, Shaanan, B. | 登録日 | 1998-04-29 | 公開日 | 1998-11-18 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | An excitatory scorpion toxin with a distinctive feature: an additional alpha helix at the C terminus and its implications for interaction with insect sodium channels. Structure, 6, 1998
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4G9C
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![BU of 4g9c by Molmil](/molmil-images/mine/4g9c) | Human B-Raf Kinase Domain bound to a Type II Pyrazolopyridine Inhibitor | 分子名称: | 3-{[3-(2-cyanopropan-2-yl)benzoyl]amino}-2,6-difluoro-N-(3-methoxy-2H-pyrazolo[3,4-b]pyridin-5-yl)benzamide, Serine/threonine-protein kinase B-raf | 著者 | Voegtli, W.C, Sturgis, H.L. | 登録日 | 2012-07-23 | 公開日 | 2012-11-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Pyrazolopyridine inhibitors of B-Raf(V600E). Part 4: Rational design and kinase selectivity profile of cell potent type II inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
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7DE7
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![BU of 7de7 by Molmil](/molmil-images/mine/7de7) | Crystal structure of PDZD7 HHD domain | 分子名称: | (2R)-2-{[(2R)-2-{[(2S)-2-{[(2R)-2-hydroxypropyl]oxy}propyl]oxy}propyl]oxy}propan-1-ol, PDZ domain-containing protein 7 | 著者 | Wang, H, Lin, L, Lu, Q. | 登録日 | 2020-11-02 | 公開日 | 2021-08-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Structure and Membrane Targeting of the PDZD7 Harmonin Homology Domain (HHD) Associated With Hearing Loss. Front Cell Dev Biol, 9, 2021
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5K4J
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![BU of 5k4j by Molmil](/molmil-images/mine/5k4j) | Crystal Structure of CDK2 in complex with compound 22 | 分子名称: | 1-[(1~{S})-1-(4-chloranyl-3-fluoranyl-phenyl)-2-oxidanyl-ethyl]-4-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]pyridin-2-one, Cyclin-dependent kinase 2 | 著者 | Yin, J, Wang, W. | 登録日 | 2016-05-20 | 公開日 | 2016-07-06 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Discovery of (S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one (GDC-0994), an Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibitor in Early Clinical Development. J.Med.Chem., 59, 2016
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5K4I
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![BU of 5k4i by Molmil](/molmil-images/mine/5k4i) | Crystal Structure of ERK2 in complex with compound 22 | 分子名称: | 1,2-ETHANEDIOL, 1-[(1~{S})-1-(4-chloranyl-3-fluoranyl-phenyl)-2-oxidanyl-ethyl]-4-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]pyridin-2-one, Mitogen-activated protein kinase 1 | 著者 | Yin, J, Wang, W. | 登録日 | 2016-05-20 | 公開日 | 2016-07-06 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Discovery of (S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one (GDC-0994), an Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibitor in Early Clinical Development. J.Med.Chem., 59, 2016
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6NKO
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![BU of 6nko by Molmil](/molmil-images/mine/6nko) | Crystal structure of ForH | 分子名称: | ForH | 著者 | Zheng, J, Irani, S, Zhang, Y. | 登録日 | 2019-01-07 | 公開日 | 2019-04-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.403 Å) | 主引用文献 | Identification of the Formycin A Biosynthetic Gene Cluster from Streptomyces kaniharaensis Illustrates the Interplay between Biological Pyrazolopyrimidine Formation and de Novo Purine Biosynthesis. J. Am. Chem. Soc., 141, 2019
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1ES4
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![BU of 1es4 by Molmil](/molmil-images/mine/1es4) | |