2WRS

Crystal Structure of the Mono-Zinc Metallo-beta-lactamase VIM-4 from Pseudomonas aeruginosa

Summary for 2WRS

• Entry DOI: 10.2210/pdb2wrs/pdb
• Related: 2WHG
• Descriptor: BETA-LACTAMASE VIM-4, ZINC ION, CITRATE ANION, ... (5 entities in total)
• Functional Keywords: hydrolase
• Biological source: PSEUDOMONAS AERUGINOSA
• Total number of polymer chains: 2
• Total formula weight: 49785.57

Authors

Lassaux, P.,Hamel, M.,Gulea, M.,Delbruck, H.,Traore, D.A.K.,Mercuri, P.S.,Horsfall, L.,Dehareng, D.,Gaumont, A.-C.,Frere, J.-M.,Ferrer, J.-L.,Hoffmann, K.,Galleni, M.,Bebrone, C. (deposition date: 2009-09-02, release date: 2010-06-23, Last modification date: 2023-12-20)

• Primary citation: Lassaux, P.,Hamel, M.,Gulea, M.,Delbruck, H.,Mercuri, P.S.,Horsfall, L.,Dehareng, D.,Kupper, M.,Frere, J.-M.,Hoffmann, K.,Galleni, M.,Bebrone, C.; Mercaptophosphonate Compounds as Broad-Spectrum Inhibitors of the Metallo-Beta-Lactamases.; J.Med.Chem., 53:4862-, 2010; PubMed: 20527888; DOI: 10.1021/JM100213C

Experimental method

X-RAY DIFFRACTION (2.79 Å)