2WRS

Crystal Structure of the Mono-Zinc Metallo-beta-lactamase VIM-4 from Pseudomonas aeruginosa

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008800	molecular_function	beta-lactamase activity
A	0017001	biological_process	antibiotic catabolic process
A	0042597	cellular_component	periplasmic space
B	0008800	molecular_function	beta-lactamase activity
B	0017001	biological_process	antibiotic catabolic process
B	0042597	cellular_component	periplasmic space

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 1262

Chain	Residue
A	HIS114
A	HIS116
A	HIS179
A	FLC1263

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 1262

Chain	Residue
B	HIS114
B	HIS116
B	HIS179
B	FLC1263

---

site_id	AC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE FLC B 1263

Chain	Residue
B	HIS114
B	HIS116
B	ASP118
B	HIS179
B	CYS198
B	ASN210
B	HIS240
B	ZN1262
B	PHE62

---

site_id	AC4
Number of Residues	12
Details	BINDING SITE FOR RESIDUE FLC A 1263

Chain	Residue
A	PHE62
A	HIS114
A	ASP118
A	HIS179
A	CYS198
A	ARG205
A	GLY209
A	ASN210
A	HIS240
A	ZN1262
A	HOH2025
A	HOH2026

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CIT A 1264

Chain	Residue
A	ARG109
A	ARG166
A	PHE167
A	GLY168

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CIT A 1265

Chain	Residue
A	ARG127
A	GLY130
A	VAL131
A	THR133
A	THR152
A	HIS153

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