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5KCN
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BU of 5kcn by Molmil
Crystal Structure of full-length LpoA from Haemophilus influenzae at 1.97 angstrom resolution
分子名称: CHLORIDE ION, Penicillin-binding protein activator LpoA
著者Sathiyamoorthy, K, Saper, M.A.
登録日2016-06-06
公開日2017-09-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.965 Å)
主引用文献Structural analyses of the Haemophilus influenzae peptidoglycan synthase activator LpoA suggest multiple conformations in solution.
J. Biol. Chem., 292, 2017
7UHE
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BU of 7uhe by Molmil
Taf14 ET domain in complex with C-terminal tail of Taf2
分子名称: C-terminal tail of Transcription initiation factor TFIID subunit 2, Transcription initiation factor TFIID subunit 14
著者Klein, B.J, Kutateladze, T.G.
登録日2022-03-26
公開日2022-08-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Taf2 mediates DNA binding of Taf14.
Nat Commun, 13, 2022
8TNS
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BU of 8tns by Molmil
Solution structure of poly(UG) RNA (GU)12 G-quadruplex
分子名称: RNA (5'-R(*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*U)-3')
著者Escobar, C.A, Petersen, R, Butcher, S.E.
登録日2023-08-02
公開日2023-11-15
最終更新日2024-05-15
実験手法SOLUTION NMR, SOLUTION SCATTERING
主引用文献Solution Structure of Poly(UG) RNA.
J.Mol.Biol., 435, 2023
5SWD
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BU of 5swd by Molmil
Structure of the adenine riboswitch aptamer domain in an intermediate-bound state
分子名称: ADENINE, MAGNESIUM ION, Vibrio vulnificus strain 93U204 chromosome II, ...
著者Stagno, J.R, Wang, Y.-X, Liu, Y, Bhandari, Y.R, Conrad, C.E, Nelson, G, Li, C, Wendel, D.R, White, T.A, Barty, A, Tuckey, R.A, Zatsepin, N.A, Grant, T.D, Fromme, P, Tan, K, Ji, X, Spence, J.C.H.
登録日2016-08-08
公開日2016-11-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography.
Nature, 541, 2017
5SWE
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BU of 5swe by Molmil
Ligand-bound structure of adenine riboswitch aptamer domain converted in crystal from its ligand-free state using ligand mixing serial femtosecond crystallography
分子名称: ADENINE, Vibrio vulnificus strain 93U204 chromosome II, adenine riboswitch aptamer domain
著者Stagno, J.R, Wang, Y.-X, Liu, Y, Bhandari, Y.R, Conrad, C.E, Nelson, G, Li, C, Wendel, D.R, White, T.A, Barty, A, Tuckey, R.A, Zatsepin, N.A, Grant, T.D, Fromme, P, Tan, K, Ji, X, Spence, J.C.H.
登録日2016-08-08
公開日2016-11-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography.
Nature, 541, 2017
6THP
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BU of 6thp by Molmil
Neprilysin in complex with the inhibitor (R)-4-(1-carboxy-3-(3'-chlorobiphenyl-4-yl)propan-2-ylamino)-4-oxobutanoic acid
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[[(2~{R})-1-[4-(3-chlorophenyl)phenyl]-4-oxidanyl-4-oxidanylidene-butan-2-yl]amino]-4-oxidanylidene-butanoic acid, Neprilysin, ...
著者Schiering, N, Wiesmann, C.
登録日2019-11-21
公開日2020-02-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Structure-Guided Design of Substituted Biphenyl Butanoic Acid Derivatives as Neprilysin Inhibitors.
Acs Med.Chem.Lett., 11, 2020
6VFO
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BU of 6vfo by Molmil
Solution structure of the PHD of mouse UHRF1 (NP95)
分子名称: E3 ubiquitin-protein ligase UHRF1, ZINC ION
著者Lemak, A, Houliston, S, Duan, S, Arrowsmith, C.H.
登録日2020-01-06
公開日2020-06-17
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Alternative splicing and allosteric regulation modulate the chromatin binding of UHRF1.
Nucleic Acids Res., 48, 2020
6VED
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BU of 6ved by Molmil
Solution structure of the TTD and linker region of UHRF1
分子名称: E3 ubiquitin-protein ligase UHRF1
著者Lemak, A, Houliston, S, Duan, S, Ong, M.S, Arrowsmith, C.H.
登録日2019-12-31
公開日2020-06-17
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Alternative splicing and allosteric regulation modulate the chromatin binding of UHRF1.
Nucleic Acids Res., 48, 2020
6VEE
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BU of 6vee by Molmil
Solution structure of the TTD and linker region of mouse UHRF1 (NP95)
分子名称: E3 ubiquitin-protein ligase UHRF1
著者Lemak, A, Houliston, S, Duan, S, Arrowsmith, C.H.
登録日2019-12-31
公開日2020-06-17
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Alternative splicing and allosteric regulation modulate the chromatin binding of UHRF1.
Nucleic Acids Res., 48, 2020
6WAI
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BU of 6wai by Molmil
Crystal Structure of SmcR N142D from Vibrio vulnificus
分子名称: 1,2-ETHANEDIOL, LuxR family transcriptional regulator, SULFATE ION
著者Newman, J.D, Russell, M.M, Gonzalez-Gutierrez, G, van Kessel, J.C.
登録日2020-03-25
公開日2020-06-17
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.583 Å)
主引用文献The DNA binding domain of the Vibrio vulnificus SmcR transcription factor is flexible and binds diverse DNA sequences.
Nucleic Acids Res., 49, 2021
6WAE
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BU of 6wae by Molmil
Crystal Structure of 6X-His tagged SmcR
分子名称: 1,2-ETHANEDIOL, LuxR family transcriptional regulator, SULFATE ION
著者Newman, J.D, Russell, M.M, Gonzalez-Gutierrez, G, van Kessel, J.C.
登録日2020-03-25
公開日2020-06-17
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献The DNA binding domain of the Vibrio vulnificus SmcR transcription factor is flexible and binds diverse DNA sequences.
Nucleic Acids Res., 49, 2021
6WAG
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BU of 6wag by Molmil
Crystal Structure of SmcR S76A from Vibrio Vulnificus
分子名称: 1,2-ETHANEDIOL, LuxR family transcriptional regulator, SULFATE ION
著者Newman, J.D, Russell, M.M, Gonzalez-Gutierrez, G, van Kessel, J.C.
登録日2020-03-25
公開日2020-06-17
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.575 Å)
主引用文献The DNA binding domain of the Vibrio vulnificus SmcR transcription factor is flexible and binds diverse DNA sequences.
Nucleic Acids Res., 49, 2021
6WVG
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BU of 6wvg by Molmil
human CD53
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Green fluorescent protein, ...
著者Yang, Y, Liu, S, Li, W.
登録日2020-05-06
公開日2020-09-16
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Open conformation of tetraspanins shapes interaction partner networks on cell membranes.
Embo J., 39, 2020
6WAF
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BU of 6waf by Molmil
Crystal Structure of SmcR N55I from Vibrio vulnificus
分子名称: LuxR family transcriptional regulator, SULFATE ION
著者Newman, J.D, Russell, M.M, Gonzalez-Gutierrez, G, van Kessel, J.C.
登録日2020-03-25
公開日2020-06-17
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.381 Å)
主引用文献The DNA binding domain of the Vibrio vulnificus SmcR transcription factor is flexible and binds diverse DNA sequences.
Nucleic Acids Res., 49, 2021
6WAH
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BU of 6wah by Molmil
Crystal Structure of SmcR L139R from Vibrio vulnificus
分子名称: 1,2-ETHANEDIOL, LuxR family transcriptional regulator, SULFATE ION
著者Newman, J.D, Russell, M.M, Gonzalez-Gutierrez, G, van Kessel, J.C.
登録日2020-03-25
公開日2020-06-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The DNA binding domain of the Vibrio vulnificus SmcR transcription factor is flexible and binds diverse DNA sequences.
Nucleic Acids Res., 49, 2021
6X9O
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BU of 6x9o by Molmil
High resolution cryoEM structure of huntingtin in complex with HAP40
分子名称: 40-kDa huntingtin-associated protein, Huntingtin
著者Harding, R.J, Deme, J.C, Lea, S.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC)
登録日2020-06-03
公開日2020-06-17
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1.
Commun Biol, 4, 2021
5E54
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BU of 5e54 by Molmil
Two apo structures of the adenine riboswitch aptamer domain determined using an X-ray free electron laser
分子名称: MAGNESIUM ION, Vibrio vulnificus strain 93U204 chromosome II, adenine riboswitch aptamer domain
著者Stagno, J.R, Wang, Y.-X, Liu, Y, Bhandari, Y.R, Conrad, C.E, Nelson, G, Li, C, Wendel, D.R, White, T.A, Barty, A, Tuckey, R.A, Zatsepin, N.A, Grant, T.D, Fromme, P, Tan, K, Ji, X, Spence, J.C.H.
登録日2015-10-07
公開日2016-11-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography.
Nature, 541, 2017
5VAT
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BU of 5vat by Molmil
Haemophilus influenzae LpoA: Monoclinic form (Mon2) with 2 molecules per a.u.
分子名称: Penicillin-binding protein activator LpoA
著者Saper, M.A, Sathiyamoorthy, K.
登録日2017-03-27
公開日2017-09-13
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural analyses of the Haemophilus influenzae peptidoglycan synthase activator LpoA suggest multiple conformations in solution.
J. Biol. Chem., 292, 2017
5VBG
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BU of 5vbg by Molmil
Crystal Structure of full-length LpoA, Monoclinic form 1, from Haemophilus influenzae
分子名称: CHLORIDE ION, Penicillin-binding protein activator LpoA
著者Sathiyamoorthy, K, Saper, M.A.
登録日2017-03-29
公開日2017-09-13
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural analyses of the Haemophilus influenzae peptidoglycan synthase activator LpoA suggest multiple conformations in solution.
J. Biol. Chem., 292, 2017
6PMO
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BU of 6pmo by Molmil
Co-crystal structure of the Geobacillus kaustophilus glyQ T-box riboswitch discriminator domain in complex with tRNA-Gly
分子名称: IRIDIUM ION, MAGNESIUM ION, T-box riboswitch discriminator, ...
著者Li, S, Zhang, J.
登録日2019-07-02
公開日2019-11-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.65703368 Å)
主引用文献Structural basis of amino acid surveillance by higher-order tRNA-mRNA interactions.
Nat.Struct.Mol.Biol., 26, 2019
6POM
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BU of 6pom by Molmil
Cryo-EM structure of the full-length Bacillus subtilis glyQS T-box riboswitch in complex with tRNA-Gly
分子名称: T-box GlyQS leader (155-MER), tRNAGly (75-MER)
著者Li, S, Su, Z, Zhang, J, Chiu, W.
登録日2019-07-04
公開日2019-11-20
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Structural basis of amino acid surveillance by higher-order tRNA-mRNA interactions.
Nat.Struct.Mol.Biol., 26, 2019
8EVK
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BU of 8evk by Molmil
Crystal structure of Helicobacter pylori dihydroneopterin aldolase (DHNA)
分子名称: 1,2-ETHANEDIOL, Dihydroneopterin aldolase, PTERINE
著者Shaw, G.X, Cherry, S, Tropea, J.E, Ji, X.
登録日2022-10-20
公開日2023-03-01
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Structure of Helicobacter pylori dihydroneopterin aldolase suggests a fragment-based strategy for isozyme-specific inhibitor design.
Curr Res Struct Biol, 5, 2023
3GT6
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BU of 3gt6 by Molmil
Crystal Structure of the hspA from Xanthomonas axonopodis
分子名称: Low molecular weight heat shock protein
著者Hilario, E, Medrano, F.J, Bertolini, M.C.
登録日2009-03-27
公開日2011-02-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structures of Xanthomonas small heat shock protein provide a structural basis for an active molecular chaperone oligomer.
J.Mol.Biol., 408, 2011
8F4O
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BU of 8f4o by Molmil
Apo structure of the TPP riboswitch aptamer domain
分子名称: IRIDIUM HEXAMMINE ION, TETRAETHYLENE GLYCOL, TPP riboswitch aptamer domain, ...
著者Lee, H.-K, Wang, Y.-X, Stagno, J.R.
登録日2022-11-11
公開日2023-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structure of Escherichia coli thiamine pyrophosphate-sensing riboswitch in the apo state.
Structure, 31, 2023
5IBS
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BU of 5ibs by Molmil
Structure of E76Q, a Cancer-Associated Mutation of the Oncogenic Phosphatase SHP2
分子名称: Tyrosine-protein phosphatase non-receptor type 11
著者Blacklow, S.C, Stams, T, Fodor, M, LaRochelle, J.R.
登録日2016-02-22
公開日2016-04-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Structural and Functional Consequences of Three Cancer-Associated Mutations of the Oncogenic Phosphatase SHP2.
Biochemistry, 55, 2016

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