1R4M
 
 | | APPBP1-UBA3-NEDD8, an E1-ubiquitin-like protein complex | | 分子名称: | Ubiquitin-like protein NEDD8, ZINC ION, amyloid beta precursor protein-binding protein 1, ... | | 著者 | Walden, H, Podgorski, M.S, Holton, J.M, Schulman, B.A. | | 登録日 | 2003-10-07 | | 公開日 | 2003-12-23 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1.
Mol.Cell, 12, 2003
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1TT5
 | | Structure of APPBP1-UBA3-Ubc12N26: a unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8 | | 分子名称: | Ubiquitin-conjugating enzyme E2 M, ZINC ION, amyloid protein-binding protein 1, ... | | 著者 | Huang, D.T, Miller, D.W, Mathew, R, Cassell, R, Holton, J.M, Roussel, M.F, Schulman, B.A. | | 登録日 | 2004-06-21 | | 公開日 | 2004-09-14 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8.
Nat.Struct.Mol.Biol., 11, 2004
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7KTX
 | | Cryo-EM structure of Saccharomyces cerevisiae ER membrane protein complex bound to a Fab in DDM detergent | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ER membrane protein complex subunit 1, ER membrane protein complex subunit 2, ... | | 著者 | Miller-Vedam, L.E, Schirle Oakdale, N.S, Braeuning, B, Boydston, E.A, Sevillano, N, Popova, K.D, Bonnar, J.L, Shurtleff, M.J, Prabu, J.R, Stroud, R.M, Craik, C.S, Schulman, B.A, Weissman, J.S, Frost, A. | | 登録日 | 2020-11-24 | | 公開日 | 2020-12-02 | | 最終更新日 | 2020-12-09 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients.
Elife, 9, 2020
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7KRA
 | | Cryo-EM structure of Saccharomyces cerevisiae ER membrane protein complex bound to Fab-DH4 in lipid nanodiscs | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ER membrane protein complex subunit 1, ER membrane protein complex subunit 2, ... | | 著者 | Miller-Vedam, L.E, Schirle Oakdale, N.S, Braeuning, B, Boydston, E.A, Sevillano, N, Popova, K.D, Bonnar, J.L, Shurtleff, M.J, Prabu, J.R, Stroud, R.M, Craik, C.S, Schulman, B.A, Weissman, J.S, Frost, A. | | 登録日 | 2020-11-19 | | 公開日 | 2020-12-02 | | 最終更新日 | 2020-12-09 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients.
Elife, 9, 2020
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7KWA
 | | Structure of DCN1 bound to N-((4S,5S)-3-(aminomethyl)-7-ethyl-4-(4-fluorophenyl)-6-oxo-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl)-3-(trifluoromethyl)benzamide | | 分子名称: | Endolysin,DCN1-like protein 1, N-[(4S,5S)-3-(aminomethyl)-7-ethyl-4-(4-fluorophenyl)-6-oxo-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl]-3-(trifluoromethyl)benzamide | | 著者 | Kim, H.S, Hammill, J.T, Schulman, B.A, Guy, R.K, Scott, D.C. | | 登録日 | 2020-11-30 | | 公開日 | 2021-07-14 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.572 Å) | | 主引用文献 | Improvement of Oral Bioavailability of Pyrazolo-Pyridone Inhibitors of the Interaction of DCN1/2 and UBE2M.
J.Med.Chem., 64, 2021
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1Y8X
 | | Structural basis for recruitment of Ubc12 by an E2-binding domain in NEDD8's E1 | | 分子名称: | Ubiquitin-activating enzyme E1C, Ubiquitin-conjugating enzyme E2 M | | 著者 | Huang, D.T, Paydar, A, Zhuang, M, Waddell, M.B, Holton, J.M, Schulman, B.A. | | 登録日 | 2004-12-13 | | 公開日 | 2005-02-08 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1.
Mol.Cell, 17, 2005
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1YOV
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1ZFN
 | | Structural Analysis of Escherichia coli ThiF | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Adenylyltransferase thiF, ZINC ION | | 著者 | Duda, D.M, Walden, H, Sfondouris, J, Schulman, B.A. | | 登録日 | 2005-04-20 | | 公開日 | 2005-06-14 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structural Analysis of Escherichia Coli ThiF.
J.Mol.Biol., 349, 2005
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1ZKM
 | | Structural Analysis of Escherichia Coli ThiF | | 分子名称: | Adenylyltransferase thiF, ZINC ION | | 著者 | Duda, D.M, Walden, H, Sfondouris, J, Schulman, B.A. | | 登録日 | 2005-05-03 | | 公開日 | 2005-06-14 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structural Analysis of Escherichia Coli ThiF.
J.Mol.Biol., 349, 2005
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2AST
 | | Crystal structure of Skp1-Skp2-Cks1 in complex with a p27 peptide | | 分子名称: | BENZAMIDINE, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinases regulatory subunit 1, ... | | 著者 | Hao, B, Zhang, N, Schulman, B.A, Wu, G, Pagano, M, Pavletich, N.P. | | 登録日 | 2005-08-24 | | 公開日 | 2005-10-18 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Basis of the Cks1-Dependent Recognition of p27(Kip1) by the SCF(Skp2) Ubiquitin Ligase.
Mol.Cell, 20, 2005
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2ASS
 | | Crystal structure of the Skp1-Skp2-Cks1 complex | | 分子名称: | BENZAMIDINE, Cyclin-dependent kinases regulatory subunit 1, PHOSPHATE ION, ... | | 著者 | Hao, B, Zhang, N, Schulman, B.A, Wu, G, Pagano, M, Pavletich, N.P. | | 登録日 | 2005-08-24 | | 公開日 | 2005-10-18 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Basis of the Cks1-Dependent Recognition of p27(Kip1) by the SCF(Skp2) Ubiquitin Ligase.
Mol.Cell, 20, 2005
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2EKE
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3H5R
 | | Crystal structure of E. coli MccB + Succinimide | | 分子名称: | MccB protein, Microcin C7 analog, SULFATE ION, ... | | 著者 | Regni, C.A, Roush, R.F, Miller, D, Nourse, A, Walsh, C.T, Schulman, B.A. | | 登録日 | 2009-04-22 | | 公開日 | 2009-06-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | How the MccB bacterial ancestor of ubiquitin E1 initiates biosynthesis of the microcin C7 antibiotic.
Embo J., 28, 2009
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3H5A
 | | Crystal structure of E. coli MccB | | 分子名称: | MccB protein, ZINC ION | | 著者 | Regni, C.A, Roush, R.F, Miller, D, Nourse, A, Walsh, C.T, Schulman, B.A. | | 登録日 | 2009-04-21 | | 公開日 | 2009-06-16 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | How the MccB bacterial ancestor of ubiquitin E1 initiates biosynthesis of the microcin C7 antibiotic.
Embo J., 28, 2009
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3H9G
 | | Crystal structure of E. coli MccB + MccA-N7isoASN | | 分子名称: | MccB protein, Microcin C7 analog, SULFATE ION, ... | | 著者 | Regni, C.A, Roush, R.F, Miller, D, Nourse, A, Walsh, C.T, Schulman, B.A. | | 登録日 | 2009-04-30 | | 公開日 | 2009-06-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | How the MccB bacterial ancestor of ubiquitin E1 initiates biosynthesis of the microcin C7 antibiotic.
Embo J., 28, 2009
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3H9Q
 | | Crystal structure of E. coli MccB + SeMet MccA | | 分子名称: | MccB protein, Microcin C7 ANALOG, SULFATE ION, ... | | 著者 | Regni, C.A, Roush, R.F, Miller, D, Nourse, A, Walsh, C.T, Schulman, B.A. | | 登録日 | 2009-04-30 | | 公開日 | 2009-06-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | | 主引用文献 | How the MccB bacterial ancestor of ubiquitin E1 initiates biosynthesis of the microcin C7 antibiotic.
Embo J., 28, 2009
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3H9J
 | | Crystal structure of E. coli MccB + AMPCPP + SeMeT MccA | | 分子名称: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MccB protein, Microcin C7 ANALOG, ... | | 著者 | Regni, C.A, Roush, R.F, Miller, D, Nourse, A, Walsh, C.T, Schulman, B.A. | | 登録日 | 2009-04-30 | | 公開日 | 2009-06-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | How the MccB bacterial ancestor of ubiquitin E1 initiates biosynthesis of the microcin C7 antibiotic.
Embo J., 28, 2009
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3HQL
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3HQM
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3HU6
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3HSV
 | | Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx-MacroH2ASBCpep2 | | 分子名称: | Core histone macro-H2A.1, SULFATE ION, Speckle-type POZ protein, ... | | 著者 | Zhuang, M, Schulman, B.A, Miller, D. | | 登録日 | 2009-06-10 | | 公開日 | 2009-10-20 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
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3HYM
 | | Insights into Anaphase Promoting Complex TPR subdomain assembly from a CDC26-APC6 structure | | 分子名称: | Anaphase-promoting complex subunit CDC26, Cell division cycle protein 16 homolog | | 著者 | Wang, J, Dye, B.T, Rajashankar, K.R, Kurinov, I, Schulman, B.A. | | 登録日 | 2009-06-22 | | 公開日 | 2009-08-11 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Insights into anaphase promoting complex TPR subdomain assembly from a CDC26-APC6 structure.
Nat.Struct.Mol.Biol., 16, 2009
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3HVE
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3HTM
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3HQH
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