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4JHA
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Crystal Structure of RSV-Neutralizing Human Antibody D25
分子名称: D25 antigen-binding fragment heavy chain, D25 light chain
著者Mclellan, J.S, Chen, M, Leung, S, Graepel, K.W, Du, X, Yang, Y, Zhou, T, Baxa, U, Yasuda, E, Beaumont, T, Kumar, A, Modjarrad, K, Zheng, Z, Zhao, M, Xia, N, Kwong, P.D, Graham, B.S.
登録日2013-03-04
公開日2013-05-01
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody.
Science, 340, 2013
4JAM
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BU of 4jam by Molmil
Crystal structure of broadly neutralizing anti-hiv-1 antibody ch103
分子名称: 1,2-ETHANEDIOL, ANTIGEN BINDING FRAGMENT OF HEAVY CHAIN of CH103, ANTIGEN BINDING FRAGMENT OF LIGHT CHAIN of CH103, ...
著者Zhou, T, Moquin, S, Zheng, A, Srivatsan, S, Kwong, P.D.
登録日2013-02-18
公開日2013-04-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus.
Nature, 496, 2013
4I3R
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BU of 4i3r by Molmil
Crystal structure of the outer domain of HIV-1 gp120 in complex with VRC-PG04 space group P3221
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of VRC-PG04 Fab, Light chain of VRC-PG04 Fab, ...
著者Joyce, M.G, Biertumpfel, C, Nabel, G.J, Kwong, P.D.
登録日2012-11-26
公開日2013-01-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Outer Domain of HIV-1 gp120: Antigenic Optimization, Structural Malleability, and Crystal Structure with Antibody VRC-PG04.
J.Virol., 87, 2013
4JHW
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BU of 4jhw by Molmil
Crystal Structure of Respiratory Syncytial Virus Fusion Glycoprotein Stabilized in the Prefusion Conformation by Human Antibody D25
分子名称: D25 antigen-binding fragment heavy chain, D25 light chain, Fusion glycoprotein F0
著者Mclellan, J.S, Chen, M, Leung, S, Graepel, K.W, Du, X, Yang, Y, Zhou, T, Baxa, U, Yasuda, E, Beaumont, T, Kumar, A, Modjarrad, K, Zheng, Z, Zhao, M, Xia, N, Kwong, P.D, Graham, B.S.
登録日2013-03-05
公開日2013-05-01
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody.
Science, 340, 2013
4JPV
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BU of 4jpv by Molmil
Crystal structure of broadly and potently neutralizing antibody 3bnc117 in complex with hiv-1 gp120
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Zhou, T, Moquin, S, Kwong, P.D.
登録日2013-03-19
公開日2013-04-17
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.827 Å)
主引用文献Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization.
Cell(Cambridge,Mass.), 153, 2013
4JB9
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BU of 4jb9 by Molmil
Crystal structure of antibody VRC06 in complex with HIV-1 gp120 core
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, antibody VRC06 heavy chain, antibody VRC06 light chain, ...
著者Kwon, Y.D, Zhou, T, Srivatsan, S, Kwong, P.D.
登録日2013-02-19
公開日2013-05-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization.
Science, 340, 2013
4I3S
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BU of 4i3s by Molmil
Crystal structure of the outer domain of HIV-1 gp120 in complex with VRC-PG04 space group P21
分子名称: CALCIUM ION, Heavy chain of VRC-PG04 Fab, Light chain of VRC-PG04 Fab, ...
著者Joyce, M.G, Biertumpfel, C, Nabel, G.J, Kwong, P.D.
登録日2012-11-26
公開日2013-01-09
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Outer Domain of HIV-1 gp120: Antigenic Optimization, Structural Malleability, and Crystal Structure with Antibody VRC-PG04.
J.Virol., 87, 2013
4J6R
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BU of 4j6r by Molmil
Crystal structure of broadly and potently neutralizing antibody VRC23 in complex with HIV-1 gp120
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, (R,R)-2,3-BUTANEDIOL, 1,2-ETHANEDIOL, ...
著者Zhou, T, Moquin, S, Kwong, P.D.
登録日2013-02-11
公開日2013-05-08
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization.
Science, 340, 2013
4JZZ
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BU of 4jzz by Molmil
Crystal structure of CD4-mimetic miniprotein M48U1 in complex with HIV-1 YU2 gp120 in C2221 space group
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CD4-MIMETIC MINIPROTEIN M48U1, CITRATE ANION, ...
著者Acharya, P, Kwong, P.D.
登録日2013-04-03
公開日2013-06-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Structural Basis for Highly Effective HIV-1 Neutralization by CD4-Mimetic Miniproteins Revealed by 1.5 A Cocrystal Structure of gp120 and M48U1.
Structure, 21, 2013
4JZW
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BU of 4jzw by Molmil
Crystal structure of CD4-mimetic miniprotein M48U1 in complex with HIV-1 YU2 gp120 in P212121 space group
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CD4-MIMETIC MINIPROTEIN M48U1, ...
著者Acharya, P, Kwong, P.D.
登録日2013-04-03
公開日2013-06-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.784 Å)
主引用文献Structural Basis for Highly Effective HIV-1 Neutralization by CD4-Mimetic Miniproteins Revealed by 1.5 A Cocrystal Structure of gp120 and M48U1.
Structure, 21, 2013
4KA2
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BU of 4ka2 by Molmil
Crystal structure of CD4-mimetic miniprotein M48U12 in complex with HIV-1 YU2 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 YU2 gp120, M48U12
著者Acharya, P, Kwong, P.D.
登録日2013-04-21
公開日2013-06-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Interfacial Cavity Filling To Optimize CD4-Mimetic Miniprotein Interactions with HIV-1 Surface Glycoprotein.
J.Med.Chem., 56, 2013
5I8H
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BU of 5i8h by Molmil
Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer in Complex with V3 Loop-targeting Antibody PGT122 Fab and Fusion Peptide-targeting Antibody VRC34.01 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.664 gp120, ...
著者Xu, K, Zhou, T, Kwong, P.D.
登録日2016-02-18
公開日2016-05-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (4.301 Å)
主引用文献Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody.
Science, 352, 2016
3O45
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BU of 3o45 by Molmil
Crystal Structure of 101F Fab Bound to 17-mer Peptide Epitope
分子名称: Fusion glycoprotein F1, Mouse monoclonal antibody 101F 101F Fab heavy chain, Mouse monoclonal antibody 101F 101F Fab light chain, ...
著者McLellan, J.S, Chen, M, Chang, J.S, Yang, Y, Kim, A, Graham, B.S, Kwong, P.D.
登録日2010-07-26
公開日2010-10-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.872 Å)
主引用文献Structure of a Major Antigenic Site on the Respiratory Syncytial Virus Fusion Glycoprotein in Complex with Neutralizing Antibody 101F.
J.Virol., 84, 2010
5JO5
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BU of 5jo5 by Molmil
Crystal structure of 10E8 gHV-gLV antigen-binding fragment.
分子名称: 10E8 gHV, 10E8 gLV
著者Joyce, M.G, Mascola, J.R, Kwong, P.D.
登録日2016-05-02
公開日2016-07-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8.
Plos One, 11, 2016
3O41
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BU of 3o41 by Molmil
Crystal Structure of 101F Fab Bound to 15-mer Peptide Epitope
分子名称: Fusion glycoprotein F1, Mouse monoclonal antibody 101F Fab heavy chain, Mouse monoclonal antibody 101F Fab light chain, ...
著者McLellan, J.S, Chen, M, Chang, J.S, Yang, Y, Kim, A, Graham, B.S, Kwong, P.D.
登録日2010-07-26
公開日2010-10-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of a Major Antigenic Site on the Respiratory Syncytial Virus Fusion Glycoprotein in Complex with Neutralizing Antibody 101F.
J.Virol., 84, 2010
5K6G
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BU of 5k6g by Molmil
Crystal structure of prefusion-stabilized RSV F single-chain 9-24 DS-Cav1 variant.
分子名称: Fusion glycoprotein F0,Fusion glycoprotein F0
著者Joyce, M.G, Zhang, B, Mascola, J.R, Kwong, P.D.
登録日2016-05-24
公開日2016-09-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.
Nat.Struct.Mol.Biol., 23, 2016
5JR1
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BU of 5jr1 by Molmil
Crystal structure of 10E8 gHV-matureL antigen-binding fragment.
分子名称: 10E8 heavy chain, 10E8 mature light chain, ZINC ION
著者Joyce, M.G, Mascola, J.R, Kwong, P.D.
登録日2016-05-05
公開日2016-07-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8.
Plos One, 11, 2016
5JXA
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BU of 5jxa by Molmil
Crystal structure of ligand-free VRC03 antigen-binding fragment.
分子名称: 1,2-ETHANEDIOL, COPPER (II) ION, PHOSPHATE ION, ...
著者Zhou, T, Moquin, S, Joyce, M.G, Mascola, J.R, Kwong, P.D.
登録日2016-05-12
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies.
Structure, 24, 2016
5K6F
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BU of 5k6f by Molmil
Crystal structure of prefusion-stabilized RSV F single-chain 9-19 DS-Cav1 variant.
分子名称: Fusion glycoprotein F0
著者Joyce, M.G, Zhang, B, Lai, Y.T, Mascola, J.R, Kwong, P.D.
登録日2016-05-24
公開日2016-08-10
最終更新日2016-09-21
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.
Nat.Struct.Mol.Biol., 23, 2016
5K6B
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BU of 5k6b by Molmil
Crystal structure of prefusion-stabilized RSV F single-chain 9 DS-Cav1 variant.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, SULFATE ION
著者Joyce, M.G, Zhang, B, Rundlet, E.J, Mascola, J.R, Kwong, P.D.
登録日2016-05-24
公開日2016-08-31
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.981 Å)
主引用文献Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.
Nat.Struct.Mol.Biol., 23, 2016
5K9J
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BU of 5k9j by Molmil
Crystal structure of multidonor HV6-1-class broadly neutralizing Influenza A antibody 56.a.09 isolated following H5 immunization.
分子名称: 56.a.09 heavy chain, 56.a.09 light chain, POLYETHYLENE GLYCOL (N=34)
著者Joyce, M.G, Thomas, P.V, Wheatley, A.K, McDermott, A.B, Mascola, J.R, Kwong, P.D.
登録日2016-05-31
公開日2016-07-27
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.904 Å)
主引用文献Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses.
Cell, 166, 2016
3ONY
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BU of 3ony by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with Fucose
分子名称: 1,2-ETHANEDIOL, Capsid protein, alpha-L-fucopyranose
著者Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
登録日2010-08-30
公開日2011-05-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structures of GII.10 and GII.12 Norovirus Protruding Domains in Complex with Histo-Blood Group Antigens Reveal Details for a Potential Site of Vulnerability.
J.Virol., 85, 2011
5K9K
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BU of 5k9k by Molmil
Crystal structure of multidonor HV6-1-class broadly neutralizing Influenza A antibody 56.a.09 in complex with Hemagglutinin Hong Kong 1968.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 56.a.09 Heavy chain, ...
著者Joyce, M.G, Thomas, P.V, Wheatley, A.K, McDermott, A.B, Mascola, J.R, Kwong, P.D.
登録日2016-05-31
公開日2016-12-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses.
Cell, 166, 2016
5K6C
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BU of 5k6c by Molmil
Crystal structure of prefusion-stabilized RSV F single-chain 9-10 DS-Cav1 variant.
分子名称: Fusion glycoprotein F0,Fusion glycoprotein F0, SULFATE ION
著者Joyce, M.G, Zhang, B, Lai, Y.T, Mascola, J.R, Kwong, P.D.
登録日2016-05-24
公開日2016-10-12
最終更新日2016-10-19
実験手法X-RAY DIFFRACTION (3.576 Å)
主引用文献Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.
Nat.Struct.Mol.Biol., 23, 2016
3ONU
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BU of 3onu by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026
分子名称: 1,2-ETHANEDIOL, Capsid protein
著者Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
登録日2010-08-30
公開日2011-05-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.395 Å)
主引用文献Crystal Structures of GII.10 and GII.12 Norovirus Protruding Domains in Complex with Histo-Blood Group Antigens Reveal Details for a Potential Site of Vulnerability.
J.Virol., 85, 2011

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