4JHA
| Crystal Structure of RSV-Neutralizing Human Antibody D25 | 分子名称: | D25 antigen-binding fragment heavy chain, D25 light chain | 著者 | Mclellan, J.S, Chen, M, Leung, S, Graepel, K.W, Du, X, Yang, Y, Zhou, T, Baxa, U, Yasuda, E, Beaumont, T, Kumar, A, Modjarrad, K, Zheng, Z, Zhao, M, Xia, N, Kwong, P.D, Graham, B.S. | 登録日 | 2013-03-04 | 公開日 | 2013-05-01 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody. Science, 340, 2013
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4JAM
| Crystal structure of broadly neutralizing anti-hiv-1 antibody ch103 | 分子名称: | 1,2-ETHANEDIOL, ANTIGEN BINDING FRAGMENT OF HEAVY CHAIN of CH103, ANTIGEN BINDING FRAGMENT OF LIGHT CHAIN of CH103, ... | 著者 | Zhou, T, Moquin, S, Zheng, A, Srivatsan, S, Kwong, P.D. | 登録日 | 2013-02-18 | 公開日 | 2013-04-03 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus. Nature, 496, 2013
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4I3R
| Crystal structure of the outer domain of HIV-1 gp120 in complex with VRC-PG04 space group P3221 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of VRC-PG04 Fab, Light chain of VRC-PG04 Fab, ... | 著者 | Joyce, M.G, Biertumpfel, C, Nabel, G.J, Kwong, P.D. | 登録日 | 2012-11-26 | 公開日 | 2013-01-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Outer Domain of HIV-1 gp120: Antigenic Optimization, Structural Malleability, and Crystal Structure with Antibody VRC-PG04. J.Virol., 87, 2013
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4JHW
| Crystal Structure of Respiratory Syncytial Virus Fusion Glycoprotein Stabilized in the Prefusion Conformation by Human Antibody D25 | 分子名称: | D25 antigen-binding fragment heavy chain, D25 light chain, Fusion glycoprotein F0 | 著者 | Mclellan, J.S, Chen, M, Leung, S, Graepel, K.W, Du, X, Yang, Y, Zhou, T, Baxa, U, Yasuda, E, Beaumont, T, Kumar, A, Modjarrad, K, Zheng, Z, Zhao, M, Xia, N, Kwong, P.D, Graham, B.S. | 登録日 | 2013-03-05 | 公開日 | 2013-05-01 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody. Science, 340, 2013
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4JPV
| Crystal structure of broadly and potently neutralizing antibody 3bnc117 in complex with hiv-1 gp120 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Zhou, T, Moquin, S, Kwong, P.D. | 登録日 | 2013-03-19 | 公開日 | 2013-04-17 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.827 Å) | 主引用文献 | Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization. Cell(Cambridge,Mass.), 153, 2013
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4JB9
| Crystal structure of antibody VRC06 in complex with HIV-1 gp120 core | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, antibody VRC06 heavy chain, antibody VRC06 light chain, ... | 著者 | Kwon, Y.D, Zhou, T, Srivatsan, S, Kwong, P.D. | 登録日 | 2013-02-19 | 公開日 | 2013-05-08 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization. Science, 340, 2013
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4I3S
| Crystal structure of the outer domain of HIV-1 gp120 in complex with VRC-PG04 space group P21 | 分子名称: | CALCIUM ION, Heavy chain of VRC-PG04 Fab, Light chain of VRC-PG04 Fab, ... | 著者 | Joyce, M.G, Biertumpfel, C, Nabel, G.J, Kwong, P.D. | 登録日 | 2012-11-26 | 公開日 | 2013-01-09 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Outer Domain of HIV-1 gp120: Antigenic Optimization, Structural Malleability, and Crystal Structure with Antibody VRC-PG04. J.Virol., 87, 2013
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4J6R
| Crystal structure of broadly and potently neutralizing antibody VRC23 in complex with HIV-1 gp120 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, (R,R)-2,3-BUTANEDIOL, 1,2-ETHANEDIOL, ... | 著者 | Zhou, T, Moquin, S, Kwong, P.D. | 登録日 | 2013-02-11 | 公開日 | 2013-05-08 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization. Science, 340, 2013
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4JZZ
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4JZW
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4KA2
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5I8H
| Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer in Complex with V3 Loop-targeting Antibody PGT122 Fab and Fusion Peptide-targeting Antibody VRC34.01 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.664 gp120, ... | 著者 | Xu, K, Zhou, T, Kwong, P.D. | 登録日 | 2016-02-18 | 公開日 | 2016-05-25 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (4.301 Å) | 主引用文献 | Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody. Science, 352, 2016
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3O45
| Crystal Structure of 101F Fab Bound to 17-mer Peptide Epitope | 分子名称: | Fusion glycoprotein F1, Mouse monoclonal antibody 101F 101F Fab heavy chain, Mouse monoclonal antibody 101F 101F Fab light chain, ... | 著者 | McLellan, J.S, Chen, M, Chang, J.S, Yang, Y, Kim, A, Graham, B.S, Kwong, P.D. | 登録日 | 2010-07-26 | 公開日 | 2010-10-13 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.872 Å) | 主引用文献 | Structure of a Major Antigenic Site on the Respiratory Syncytial Virus Fusion Glycoprotein in Complex with Neutralizing Antibody 101F. J.Virol., 84, 2010
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5JO5
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3O41
| Crystal Structure of 101F Fab Bound to 15-mer Peptide Epitope | 分子名称: | Fusion glycoprotein F1, Mouse monoclonal antibody 101F Fab heavy chain, Mouse monoclonal antibody 101F Fab light chain, ... | 著者 | McLellan, J.S, Chen, M, Chang, J.S, Yang, Y, Kim, A, Graham, B.S, Kwong, P.D. | 登録日 | 2010-07-26 | 公開日 | 2010-10-13 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure of a Major Antigenic Site on the Respiratory Syncytial Virus Fusion Glycoprotein in Complex with Neutralizing Antibody 101F. J.Virol., 84, 2010
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5K6G
| Crystal structure of prefusion-stabilized RSV F single-chain 9-24 DS-Cav1 variant. | 分子名称: | Fusion glycoprotein F0,Fusion glycoprotein F0 | 著者 | Joyce, M.G, Zhang, B, Mascola, J.R, Kwong, P.D. | 登録日 | 2016-05-24 | 公開日 | 2016-09-28 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV. Nat.Struct.Mol.Biol., 23, 2016
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5JR1
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5JXA
| Crystal structure of ligand-free VRC03 antigen-binding fragment. | 分子名称: | 1,2-ETHANEDIOL, COPPER (II) ION, PHOSPHATE ION, ... | 著者 | Zhou, T, Moquin, S, Joyce, M.G, Mascola, J.R, Kwong, P.D. | 登録日 | 2016-05-12 | 公開日 | 2016-07-27 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies. Structure, 24, 2016
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5K6F
| Crystal structure of prefusion-stabilized RSV F single-chain 9-19 DS-Cav1 variant. | 分子名称: | Fusion glycoprotein F0 | 著者 | Joyce, M.G, Zhang, B, Lai, Y.T, Mascola, J.R, Kwong, P.D. | 登録日 | 2016-05-24 | 公開日 | 2016-08-10 | 最終更新日 | 2016-09-21 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV. Nat.Struct.Mol.Biol., 23, 2016
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5K6B
| Crystal structure of prefusion-stabilized RSV F single-chain 9 DS-Cav1 variant. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, SULFATE ION | 著者 | Joyce, M.G, Zhang, B, Rundlet, E.J, Mascola, J.R, Kwong, P.D. | 登録日 | 2016-05-24 | 公開日 | 2016-08-31 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.981 Å) | 主引用文献 | Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV. Nat.Struct.Mol.Biol., 23, 2016
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5K9J
| Crystal structure of multidonor HV6-1-class broadly neutralizing Influenza A antibody 56.a.09 isolated following H5 immunization. | 分子名称: | 56.a.09 heavy chain, 56.a.09 light chain, POLYETHYLENE GLYCOL (N=34) | 著者 | Joyce, M.G, Thomas, P.V, Wheatley, A.K, McDermott, A.B, Mascola, J.R, Kwong, P.D. | 登録日 | 2016-05-31 | 公開日 | 2016-07-27 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.904 Å) | 主引用文献 | Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses. Cell, 166, 2016
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3ONY
| Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with Fucose | 分子名称: | 1,2-ETHANEDIOL, Capsid protein, alpha-L-fucopyranose | 著者 | Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D. | 登録日 | 2010-08-30 | 公開日 | 2011-05-11 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal Structures of GII.10 and GII.12 Norovirus Protruding Domains in Complex with Histo-Blood Group Antigens Reveal Details for a Potential Site of Vulnerability. J.Virol., 85, 2011
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5K9K
| Crystal structure of multidonor HV6-1-class broadly neutralizing Influenza A antibody 56.a.09 in complex with Hemagglutinin Hong Kong 1968. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 56.a.09 Heavy chain, ... | 著者 | Joyce, M.G, Thomas, P.V, Wheatley, A.K, McDermott, A.B, Mascola, J.R, Kwong, P.D. | 登録日 | 2016-05-31 | 公開日 | 2016-12-21 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.97 Å) | 主引用文献 | Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses. Cell, 166, 2016
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5K6C
| Crystal structure of prefusion-stabilized RSV F single-chain 9-10 DS-Cav1 variant. | 分子名称: | Fusion glycoprotein F0,Fusion glycoprotein F0, SULFATE ION | 著者 | Joyce, M.G, Zhang, B, Lai, Y.T, Mascola, J.R, Kwong, P.D. | 登録日 | 2016-05-24 | 公開日 | 2016-10-12 | 最終更新日 | 2016-10-19 | 実験手法 | X-RAY DIFFRACTION (3.576 Å) | 主引用文献 | Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV. Nat.Struct.Mol.Biol., 23, 2016
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3ONU
| Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 | 分子名称: | 1,2-ETHANEDIOL, Capsid protein | 著者 | Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D. | 登録日 | 2010-08-30 | 公開日 | 2011-05-11 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.395 Å) | 主引用文献 | Crystal Structures of GII.10 and GII.12 Norovirus Protruding Domains in Complex with Histo-Blood Group Antigens Reveal Details for a Potential Site of Vulnerability. J.Virol., 85, 2011
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