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7Y57
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BU of 7y57 by Molmil
Crystal structure of NS1 nuclease domain in P21 space group
分子名称: NS1 protein, PHOSPHATE ION
著者Zhang, X.Y, Gan, J.H.
登録日2022-06-16
公開日2023-07-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.183 Å)
主引用文献Structures and implications of the nuclease domain of human parvovirus B19 NS1 protein.
Comput Struct Biotechnol J, 20, 2022
7XQV
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BU of 7xqv by Molmil
The complex of nanobody Rh57 binding to GTP-bound RhoA active form
分子名称: ALANINE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Zhang, Y.R, Liu, R, Ding, Y.
登録日2022-05-09
公開日2022-07-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Structural insights into the binding of nanobody Rh57 to active RhoA-GTP.
Biochem.Biophys.Res.Commun., 616, 2022
6GFM
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BU of 6gfm by Molmil
Crystal structure of the Escherichia coli nucleosidase PpnN (pppGpp-form)
分子名称: Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase, guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate)
著者Zhang, Y, Baerentsen, R.L, Gerdes, K, Brodersen, D.E.
登録日2018-05-01
公開日2019-04-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献(p)ppGpp Regulates a Bacterial Nucleosidase by an Allosteric Two-Domain Switch.
Mol.Cell, 74, 2019
6LIG
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BU of 6lig by Molmil
Crystal structure of human Glutamate oxaloacetate transaminase 1 (GOT1) in complex with AH
分子名称: 3-[3-(3-methylbut-2-enyl)-4-oxidanyl-phenyl]-5-[[3-(3-methylbut-2-enyl)-4-oxidanyl-phenyl]methylidene]-4-oxidanyl-furan-2-one, Glutamate oxaloacetate transaminase 1, PYRIDOXAL-5'-PHOSPHATE
著者Yan, S, Sun, W.G, Zhang, Y.H.
登録日2019-12-10
公開日2020-12-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Crystal structure of human Glutamate oxaloacetate transaminase 1 (GOT1) in complex with AH
To Be Published
6GFL
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BU of 6gfl by Molmil
Crystal structure of the Escherichia coli nucleosidase PpnN (apo form)
分子名称: Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase
著者Zhang, Y, Baerentsen, R.L, Gerdes, K, Brodersen, D.E.
登録日2018-05-01
公開日2019-04-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献(p)ppGpp Regulates a Bacterial Nucleosidase by an Allosteric Two-Domain Switch.
Mol.Cell, 74, 2019
2PZD
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BU of 2pzd by Molmil
Crystal Structure of the HtrA2/Omi PDZ Domain Bound to a Phage-Derived Ligand (WTMFWV)
分子名称: 1,2-ETHANEDIOL, Serine protease HTRA2
著者Appleton, B.A, Wiesmann, C.
登録日2007-05-17
公開日2007-08-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural and functional analysis of the ligand specificity of the HtrA2/Omi PDZ domain.
Protein Sci., 16, 2007
7YIR
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BU of 7yir by Molmil
Crystal structure of N-terminal PH domain of ARAP3 protein from human
分子名称: Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3, DI(HYDROXYETHYL)ETHER
著者Zhang, Y.J, Liu, Y.R, Wu, B.
登録日2022-07-18
公開日2023-05-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献Structural Insights Uncover the Specific Phosphoinositide Recognition by the PH1 Domain of Arap3.
Int J Mol Sci, 24, 2023
7YIS
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BU of 7yis by Molmil
Crystal structure of N-terminal PH domain of ARAP3 protein in complex with inositol 1,3,4,5-tetrakisphosphate
分子名称: (2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATE, Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
著者Zhang, Y.J, Liu, Y.R, Wu, B.
登録日2022-07-18
公開日2023-05-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural Insights Uncover the Specific Phosphoinositide Recognition by the PH1 Domain of Arap3.
Int J Mol Sci, 24, 2023
6LL9
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BU of 6ll9 by Molmil
Crystal structure of D-alanine-D-alanine ligase from Aeromonas hydrophila
分子名称: D-ALANINE, D-alanine--D-alanine ligase
著者Zhang, H.
登録日2019-12-22
公開日2020-07-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Insights into the Inhibition ofAeromonas hydrophilad-Alanine-d-Alanine Ligase by Integration of Kinetics and Structural Analysis.
J.Agric.Food Chem., 68, 2020
1J26
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BU of 1j26 by Molmil
Solution structure of a putative peptidyl-tRNA hydrolase domain in a mouse hypothetical protein
分子名称: immature colon carcinoma transcript 1
著者Nameki, N, Kigawa, T, Koshiba, S, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2002-12-25
公開日2004-06-01
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of the catalytic domain of the mitochondrial protein ICT1 that is essential for cell vitality
J.Mol.Biol., 2010
2OGD
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BU of 2ogd by Molmil
T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-527
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, BETA-MERCAPTOETHANOL, ...
著者Cao, R, Gao, Y, Robinson, H, Goddard, A, Oldfield, E.
登録日2007-01-05
公開日2007-10-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Bisphosphonates: Teaching Old Drugs with New Tricks
TO BE PUBLISHED
7EO7
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BU of 7eo7 by Molmil
Crystal structure of HCoV-NL63 3C-like protease in complex with an inhibitor Shikonin
分子名称: 2-[(1R)-4-methyl-1-oxidanyl-pent-3-enyl]-5,8-bis(oxidanyl)naphthalene-1,4-dione, 3C-like proteinase
著者Gao, H.X, Zhang, Y.T, Zhou, X.L, Zhong, F.L, Li, J, Zhang, J.
登録日2021-04-21
公開日2021-10-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.24916625 Å)
主引用文献Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus.
J.Virol., 96, 2022
7EO8
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BU of 7eo8 by Molmil
Crystal structure of SARS coronavirus main protease in complex with an inhibitor Shikonin
分子名称: 2-[(1R)-4-methyl-1-oxidanyl-pent-3-enyl]-5,8-bis(oxidanyl)naphthalene-1,4-dione, 3C-like proteinase
著者Zhang, Y.T, Gao, H.X, Zhou, H, Zhong, F.L, Hu, X.H, Zhou, X.L, Lin, C, Wang, Q.S, Li, J, Zhang, J.
登録日2021-04-21
公開日2021-10-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2808516 Å)
主引用文献Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus.
J.Virol., 96, 2022
7UPQ
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BU of 7upq by Molmil
Crystal structure of designed heterotrimeric assembly DHT03_1arm_A21/B/C
分子名称: DHT03 protein A, DHT03 protein B, DHT03 protein C
著者Chang, Y, Bhabha, G, Ekiert, D.C.
登録日2022-04-16
公開日2022-12-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献De novo design of obligate ABC-type heterotrimeric proteins.
Nat.Struct.Mol.Biol., 29, 2022
7UPO
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BU of 7upo by Molmil
Crystal structure of designed heterotrimeric assembly DHT03
分子名称: DHT03 protein A, DHT03 protein B, DHT03 protein C
著者Chang, Y, Bhabha, G, Ekiert, D.C.
登録日2022-04-16
公開日2022-12-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献De novo design of obligate ABC-type heterotrimeric proteins.
Nat.Struct.Mol.Biol., 29, 2022
7UPP
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BU of 7upp by Molmil
Crystal structure of designed heterotrimeric assembly DHT03_2arm_A21/B21/C long
分子名称: DHT03 protein A, DHT03 protein B, DHT03 protein C
著者Chang, Y, Bhabha, G, Ekiert, D.C.
登録日2022-04-16
公開日2022-12-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献De novo design of obligate ABC-type heterotrimeric proteins.
Nat.Struct.Mol.Biol., 29, 2022
3IAX
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BU of 3iax by Molmil
The crystal structure of the TolB box of Colicin A in complex with TolB reveals important differences in the recruitment of the common TolB translocation portal used by group A colicins
分子名称: CALCIUM ION, Colicin-A, GLYCEROL, ...
著者Li, C.
登録日2009-07-15
公開日2009-10-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The crystal structure of the TolB box of colicin A in complex with TolB reveals important differences in the recruitment of the common TolB translocation portal used by group A colicins.
Mol.Microbiol., 75, 2009
7UDK
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BU of 7udk by Molmil
Crystal structure of designed helical repeat protein RPB_LRP2_R4 bound to LRPx4 peptide
分子名称: 4xLRP, Designed helical repeat protein (DHR) RPB_LRP2_R4
著者Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C.
登録日2022-03-20
公開日2023-03-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
7UDL
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BU of 7udl by Molmil
Crystal structure of designed helical repeat protein RPB_PLP1_R6 bound to PLPx6 peptide
分子名称: 1,2-ETHANEDIOL, 6xPLP Peptide, Designed helical repeat protein (DHR) RPB_PLP1_R6
著者Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C.
登録日2022-03-20
公開日2023-03-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
7UDN
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BU of 7udn by Molmil
Crystal structure of designed helical repeat protein RPB_PLP1_R6 in alternative conformation 2
分子名称: Designed helical repeat protein (DHR) RPB_PLP1_R6
著者Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C.
登録日2022-03-20
公開日2023-03-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
7UE2
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BU of 7ue2 by Molmil
Crystal structure of designed helical repeat protein RPB_PLP3_R6 bound to PLPx6 peptide
分子名称: PLPx6 peptide, RPB_PLP3_R6
著者Chang, Y, Ekiert, D.C, Bhabha, G.
登録日2022-03-21
公開日2023-03-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
7UDM
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BU of 7udm by Molmil
Crystal structure of designed helical repeat protein RPB_PLP1_R6 in alternative conformation 1 (with peptide)
分子名称: 6xPLP, Designed helical repeat protein (DHR) RPB_PLP1_R6
著者Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C.
登録日2022-03-20
公開日2023-03-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
7DQZ
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BU of 7dqz by Molmil
Crystal structure of SARS 3C-like protease in apo form
分子名称: 3C-like proteinase
著者Zhang, Y.T, Gao, H.X, Zhou, H, Zhong, F.L, Hu, X.H, Zhou, X.L, Lin, C, Wang, Q.S, Li, J, Zhang, J.
登録日2020-12-24
公開日2021-09-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus.
J.Virol., 96, 2022
1Z33
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BU of 1z33 by Molmil
Crystal structure of Trichomonas vaginalis purine nucleoside phosphorylase
分子名称: purine nucleoside phosphorylase
著者Zhang, Y, Wang, W.H, Wu, S.W, Wang, C.C, Ealick, S.E.
登録日2005-03-10
公開日2005-03-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Identification of a subversive substrate of Trichomonas vaginalis purine nucleoside phosphorylase and the crystal structure of the enzyme-substrate complex.
J.Biol.Chem., 280, 2005
1Z39
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BU of 1z39 by Molmil
Crystal structure of Trichomonas vaginalis purine nucleoside phosphorylase complexed with 2'-deoxyinosine
分子名称: 2'-DEOXYINOSINE, purine nucleoside phosphorylase
著者Zhang, Y, Wang, W.H, Wu, S.W, Wang, C.C, Ealick, S.E.
登録日2005-03-10
公開日2005-03-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Identification of a subversive substrate of Trichomonas vaginalis purine nucleoside phosphorylase and the crystal structure of the enzyme-substrate complex.
J.Biol.Chem., 280, 2005

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