2HWR
 
 | | Structural basis for the structure-activity relationships of Peroxisome Proliferator-Activated Receptor agonists | | 分子名称: | 2-[(1-{3-[(6-BENZOYL-1-PROPYL-2-NAPHTHYL)OXY]PROPYL}-1H-INDOL-4-YL)OXY]-2-METHYLPROPANOIC ACID, Peroxisome proliferator-activated receptor gamma | | 著者 | Peng, Y.H, Lu, I.L, Mahindroo, N, Lin, C.H, Hsieh, H.P, Wu, S.Y. | | 登録日 | 2006-08-01 | | 公開日 | 2007-08-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists
J.Med.Chem., 49, 2006
|
|
2HWQ
 | | Structural basis for the structure-activity relationships of Peroxisome Proliferator-Activated Receptor agonists | | 分子名称: | Peroxisome proliferator-activated receptor gamma, [(1-{3-[(6-BENZOYL-1-PROPYL-2-NAPHTHYL)OXY]PROPYL}-1H-INDOL-5-YL)OXY]ACETIC ACID | | 著者 | Peng, Y.H, Lu, I.L, Mahindroo, N, Lin, C.H, Hsieh, H.P, Wu, S.Y. | | 登録日 | 2006-08-01 | | 公開日 | 2007-08-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists
J.Med.Chem., 49, 2006
|
|
7KMJ
 | | Hsa Siglec and Unique domains in complex with Sialyl Lewis C | | 分子名称: | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, Streptococcal hemagglutinin | | 著者 | Stubbs, H.E, Iverson, T.M. | | 登録日 | 2020-11-03 | | 公開日 | 2022-05-25 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | | 主引用文献 | Origins of glycan selectivity in streptococcal Siglec-like adhesins suggest mechanisms of receptor adaptation.
Nat Commun, 13, 2022
|
|
8T3P
 | |
3G11
 | | Structure of E. coli FabF(C163Q) in complex with dihydrophenyl platensimycin | | 分子名称: | 3-({3-[(1S,4S,4aS,6S,7S,9S,9aR)-1,6-dimethyl-2-oxo-4-phenyldecahydro-6,9-epoxy-4a,7-methanobenzo[7]annulen-1-yl]propanoyl}amino)-2,4-dihydroxybenzoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 2 | | 著者 | Soisson, S.M, Parthasarathy, G. | | 登録日 | 2009-01-29 | | 公開日 | 2009-03-17 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Synthesis and biological evaluation of platensimycin analogs.
Bioorg.Med.Chem.Lett., 19, 2009
|
|
5WFN
 | | Revised model of leiomodin 2-mediated actin regulation (alternate refinement of PDB 4RWT) | | 分子名称: | Actin-5C, Leiomodin-2, MAGNESIUM ION, ... | | 著者 | Yurtsever, Z, Eck, M.J, Dominguez, R. | | 登録日 | 2017-07-12 | | 公開日 | 2017-08-30 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of leiomodin 2 in complex with actin: a structural and functional reexamination
Biophys.J., 113, 2017
|
|
8SPM
 | | Crystal structure of NikA in complex Ni-AMA | | 分子名称: | Aspergillomarasmine A, NICKEL (II) ION, Nickel ABC transporter, ... | | 著者 | Sychantha, D, Prehna, G, Wright, G.D. | | 登録日 | 2023-05-03 | | 公開日 | 2024-04-10 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Targeting bacterial nickel transport with aspergillomarasmine A suppresses virulence-associated Ni-dependent enzymes.
Nat Commun, 15, 2024
|
|
3G0Y
 | | Structure of E. coli FabF(C163Q) in complex with dihydroplatensimycin | | 分子名称: | 3-({3-[(1S,4aS,6S,7S,9S,9aR)-1,6-dimethyl-2-oxodecahydro-6,9-epoxy-4a,7-methanobenzo[7]annulen-1-yl]propanoyl}amino)-2,4-dihydroxybenzoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 2 | | 著者 | Soisson, S.M, Parthasarathy, G. | | 登録日 | 2009-01-29 | | 公開日 | 2009-03-17 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Synthesis and biological evaluation of platensimycin analogs.
Bioorg.Med.Chem.Lett., 19, 2009
|
|
7XYD
 | | Crystal structure of TMPRSS2 in complex with Nafamostat | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-carbamimidamidobenzoic acid, CALCIUM ION, ... | | 著者 | Wang, H, Liu, X, Duan, Y, Liu, X, Sun, L, Yang, H. | | 登録日 | 2022-06-01 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry.
Nat Commun, 14, 2023
|
|
7MPK
 | | Crystal structure of TagA with UDP-GlcNAc | | 分子名称: | N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE | | 著者 | Martinez, O.E, Cascio, D, Clubb, R.T. | | 登録日 | 2021-05-04 | | 公開日 | 2021-12-29 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.993 Å) | | 主引用文献 | Insight into the molecular basis of substrate recognition by the wall teichoic acid glycosyltransferase TagA.
J.Biol.Chem., 298, 2021
|
|
8KB0
 | | Crystal structure of 01JD-AEAIIVAMV | | 分子名称: | Beta2-microglobulin, MHC class I antigen alpha chain, peptide of AIV | | 著者 | Tang, Z, Zhang, N. | | 登録日 | 2023-08-03 | | 公開日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | The impact of micropolymorphism in Anpl-UAA on structural stability and peptide presentation.
Int.J.Biol.Macromol., 267, 2024
|
|
8KB1
 | | Crystal structure of 11JD | | 分子名称: | Beta2-microglobulin, MHC class I antigen, peptide of AIV | | 著者 | Tang, Z, Zhang, N. | | 登録日 | 2023-08-03 | | 公開日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | | 主引用文献 | The impact of micropolymorphism in Anpl-UAA on structural stability and peptide presentation.
Int.J.Biol.Macromol., 267, 2024
|
|
7VUZ
 | | Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with PAMP-12, state2 | | 分子名称: | CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Li, Y, Yang, F. | | 登録日 | 2021-11-04 | | 公開日 | 2021-12-01 | | 最終更新日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | | 主引用文献 | Structure, function and pharmacology of human itch receptor complexes.
Nature, 600, 2021
|
|
7VV4
 | |
7VDM
 | |
7VV5
 | | Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with C48/80, state1 | | 分子名称: | 2-[4-methoxy-3-[[2-methoxy-3-[[2-methoxy-5-[2-(methylamino)ethyl]phenyl]methyl]-5-[2-(methylamino)ethyl]phenyl]methyl]phenyl]-~{N}-methyl-ethanamine, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Li, Y, Yang, F. | | 登録日 | 2021-11-04 | | 公開日 | 2021-12-01 | | 最終更新日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | | 主引用文献 | Structure, function and pharmacology of human itch receptor complexes.
Nature, 600, 2021
|
|
7VDL
 | |
7VDH
 | | Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with C48/80, state2 | | 分子名称: | 2-[4-methoxy-3-[[2-methoxy-3-[[2-methoxy-5-[2-(methylamino)ethyl]phenyl]methyl]-5-[2-(methylamino)ethyl]phenyl]methyl]phenyl]-~{N}-methyl-ethanamine, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Li, Y, Yang, F. | | 登録日 | 2021-09-07 | | 公開日 | 2021-12-01 | | 最終更新日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structure, function and pharmacology of human itch receptor complexes.
Nature, 600, 2021
|
|
7VV0
 | |
7VV6
 | | Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with C48/80 (local) | | 分子名称: | 2-[4-methoxy-3-[[2-methoxy-3-[[2-methoxy-5-[2-(methylamino)ethyl]phenyl]methyl]-5-[2-(methylamino)ethyl]phenyl]methyl]phenyl]-~{N}-methyl-ethanamine, CHOLESTEROL, Mas-related G-protein coupled receptor member X2 | | 著者 | Li, Y, Yang, F. | | 登録日 | 2021-11-04 | | 公開日 | 2021-12-01 | | 最終更新日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structure, function and pharmacology of human itch receptor complexes.
Nature, 600, 2021
|
|
7VUY
 | |
7VV3
 | |
4FA8
 | | Multi-pronged modulation of cytokine signaling | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage colony-stimulating factor 1, Secreted protein BARF1, ... | | 著者 | He, X, Shim, A.H. | | 登録日 | 2012-05-21 | | 公開日 | 2012-08-29 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Multipronged attenuation of macrophage-colony stimulating factor signaling by Epstein-Barr virus BARF1.
Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
7N7X
 | | Crystal structure of BCX7353(ORLADEYO) in complex with human plasma kallikrein serine protease domain at 2.1 angstrom resolution | | 分子名称: | Orladeyo, PHOSPHATE ION, Plasma kallikrein light chain | | 著者 | Krishnan, R, Yarlagadda, B.S, Kotian, P, Polach, K.J, Zhang, W. | | 登録日 | 2021-06-11 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.097 Å) | | 主引用文献 | Berotralstat (BCX7353): Structure-Guided Design of a Potent, Selective, and Oral Plasma Kallikrein Inhibitor to Prevent Attacks of Hereditary Angioedema (HAE).
J.Med.Chem., 64, 2021
|
|
3HSD
 | | Crystal structure of E. coli HPPK(Y53A) | | 分子名称: | CHLORIDE ION, GLYCEROL, HPPK, ... | | 著者 | Blaszczyk, J, Li, Y, Yan, H, Ji, X. | | 登録日 | 2009-06-10 | | 公開日 | 2010-06-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.652 Å) | | 主引用文献 | Pterin-binding site mutation Y53A, N55A or F123A and activity of E. coli HPPK.
To be Published
|
|
