7X1I
| Cryo-EM structure of human BTR1 in the outward-facing state. | 分子名称: | Isoform 1 of Solute carrier family 4 member 11, [(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8Z)-icosa-5,8,11,14-tetraenoate | 著者 | Yin, Y, Lu, Y, Zuo, P. | 登録日 | 2022-02-24 | 公開日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | 主引用文献 | Structural insights into the conformational changes of BTR1/SLC4A11 in complex with PIP 2. Nat Commun, 14, 2023
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2G2X
| X-Ray Crystal Structure Protein Q88CH6 from Pseudomonas putida. Northeast Structural Genomics Consortium Target PpR72. | 分子名称: | SULFATE ION, hypothetical protein PP5205 | 著者 | Kuzin, A.P, Chen, Y, Abashidze, M, Acton, T, Conover, K, Janjua, H, Ma, L.-C, Ho, C.K, Cunningham, K, Montelione, G, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2006-02-16 | 公開日 | 2006-03-14 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural genomics reveals EVE as a new ASCH/PUA-related domain. Proteins, 75, 2009
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7YHK
| Cryo-EM structure of the HA trimer of A/Beijing/262/1995(H1N1) in complex with neutralizing antibody 12H5 | 分子名称: | 12H5 heavy chain, 12H5 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zheng, Q, Li, S, Li, T, Xue, W, Sun, H. | 登録日 | 2022-07-13 | 公開日 | 2022-08-17 | 最終更新日 | 2023-07-19 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Identification of a cross-neutralizing antibody that targets the receptor binding site of H1N1 and H5N1 influenza viruses. Nat Commun, 13, 2022
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7XRJ
| crystal structure of N-acetyltransferase DgcN-25328 | 分子名称: | Putative NAD-dependent epimerase/dehydratase family protein, SULFATE ION | 著者 | Zhang, Y.Z, Yu, Y, Cao, H.Y, Chen, X.L, Wang, P. | 登録日 | 2022-05-10 | 公開日 | 2023-02-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Novel D-glutamate catabolic pathway in marine Proteobacteria and halophilic archaea. Isme J, 17, 2023
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2GBS
| NMR structure of Rpa0253 from Rhodopseudomonas palustris. Northeast structural genomics consortium target RpR3 | 分子名称: | Hypothetical protein Rpa0253 | 著者 | Ramelot, T.A, Cort, J.R, Conover, K, Chen, Y, Ma, L.C, Ciano, M, Xiao, R, Acton, T.B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2006-03-11 | 公開日 | 2006-04-11 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural genomics reveals EVE as a new ASCH/PUA-related domain. Proteins, 75, 2009
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7BZV
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8E6Y
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6WJ5
| Structure of human TRPA1 in complex with inhibitor GDC-0334 | 分子名称: | (4R,5S)-4-fluoro-1-[(4-fluorophenyl)sulfonyl]-5-methyl-N-({5-(trifluoromethyl)-2-[2-(trifluoromethyl)pyrimidin-5-yl]pyridin-4-yl}methyl)-L-prolinamide, Transient receptor potential cation channel subfamily A member 1 | 著者 | Rohou, A, Rouge, L, Arthur, C.P, Volgraf, M, Chen, H. | 登録日 | 2020-04-11 | 公開日 | 2021-02-17 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment. J.Exp.Med., 218, 2021
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5VXQ
| X-Ray crystallography structure of the parallel stranded duplex formed by 5-rA5-dA-rA5 | 分子名称: | AMMONIUM ION, DNA/RNA (5'-R(*AP*AP*AP*AP*A)-D(P*A)-R(P*AP*AP*AP*AP*A)-3') | 著者 | Xie, J, Chen, Y, Wei, X, Kozlov, G, Gehring, K. | 登録日 | 2017-05-23 | 公開日 | 2017-08-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.002 Å) | 主引用文献 | Influence of nucleotide modifications at the C2' position on the Hoogsteen base-paired parallel-stranded duplex of poly(A) RNA. Nucleic Acids Res., 45, 2017
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7Y4T
| Crystal structure of cMET kinase domain bound by compound 9I | 分子名称: | 2-[2-[3-(1-methylpyrazol-4-yl)quinolin-6-yl]ethyl]-6-(3-nitrophenyl)pyridazin-3-one, Hepatocyte growth factor receptor | 著者 | Qu, L.Z, Chen, Y.H. | 登録日 | 2022-06-16 | 公開日 | 2022-11-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Discovery of D6808, a Highly Selective and Potent Macrocyclic c-Met Inhibitor for Gastric Cancer Harboring MET Gene Alteration Treatment. J.Med.Chem., 65, 2022
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7Y4U
| Crystal structure of cMET kinase domain bound by compound 9Y | 分子名称: | Hepatocyte growth factor receptor, ~{N}-methyl-4-[1-[2-[3-(1-methylpyrazol-4-yl)quinolin-6-yl]ethyl]-6-oxidanylidene-pyridazin-3-yl]-2-(trifluoromethyl)benzamide | 著者 | Qu, L.Z, Chen, Y.H. | 登録日 | 2022-06-16 | 公開日 | 2022-11-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Discovery of D6808, a Highly Selective and Potent Macrocyclic c-Met Inhibitor for Gastric Cancer Harboring MET Gene Alteration Treatment. J.Med.Chem., 65, 2022
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7XV9
| Crystal structure of the Human TR4 DNA-Binding Domain | 分子名称: | Nuclear receptor subfamily 2 group C member 2, ZINC ION | 著者 | Liu, Y, Chen, Z. | 登録日 | 2022-05-21 | 公開日 | 2022-12-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.599 Å) | 主引用文献 | Structures of human TR4LBD-JAZF1 and TR4DBD-DNA complexes reveal the molecular basis of transcriptional regulation. Nucleic Acids Res., 51, 2023
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7XV8
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7XV6
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7XVA
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5IE6
| Crystal structure of a lactonase mutant in complex with substrate b | 分子名称: | (3S,7S,11E)-7,14,16-trihydroxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclotetradecin-1-one, Zearalenone hydrolase | 著者 | Zheng, Y.Y, Xu, Z.X, Liu, W.D, Chen, C.C, Guo, R.T. | 登録日 | 2016-02-25 | 公開日 | 2017-01-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Enhanced alph-Zearalenol Hydrolyzing Activity of a Mycoestrogen-Detoxifying Lactonase by Structure-Based Engineering Acs Catalysis, 6, 2016
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5IE5
| Crystal structure of a lactonase double mutant in complex with substrate a | 分子名称: | (3S,7R,11E)-7,14,16-trihydroxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclotetradecin-1-one, Zearalenone hydrolase | 著者 | Zheng, Y.Y, Xu, Z.X, Liu, W.D, Chen, C.C, Guo, R.T. | 登録日 | 2016-02-25 | 公開日 | 2017-01-04 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Enhanced alph-Zearalenol Hydrolyzing Activity of a Mycoestrogen-Detoxifying Lactonase by Structure-Based Engineering Acs Catalysis, 6, 2016
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5IE4
| Crystal structure of a lactonase mutant in complex with substrate a | 分子名称: | (3S,7R,11E)-7,14,16-trihydroxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclotetradecin-1-one, Zearalenone hydrolase | 著者 | Zheng, Y.Y, Xu, Z.X, Liu, W.D, Chen, C.C, Guo, R.T. | 登録日 | 2016-02-25 | 公開日 | 2017-01-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Enhanced alph-Zearalenol Hydrolyzing Activity of a Mycoestrogen-Detoxifying Lactonase by Structure-Based Engineering Acs Catalysis, 6, 2016
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5IE7
| Crystal structure of a lactonase double mutant in complex with substrate b | 分子名称: | (3S,7S,11E)-7,14,16-trihydroxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclotetradecin-1-one, Zearalenone hydrolase | 著者 | Zheng, Y.Y, Xu, Z.X, Liu, W.D, Chen, C.C, Guo, R.T. | 登録日 | 2016-02-25 | 公開日 | 2017-01-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Enhanced alph-Zearalenol Hydrolyzing Activity of a Mycoestrogen-Detoxifying Lactonase by Structure-Based Engineering Acs Catalysis, 6, 2016
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1M8Q
| Molecular Models of Averaged Rigor Crossbridges from Tomograms of Insect Flight Muscle | 分子名称: | Skeletal muscle Actin, Skeletal muscle Myosin II, Skeletal muscle Myosin II Essential Light Chain, ... | 著者 | Chen, L.F, Winkler, H, Reedy, M.K, Reedy, M.C, Taylor, K.A. | 登録日 | 2002-07-25 | 公開日 | 2002-09-10 | 最終更新日 | 2022-12-21 | 実験手法 | ELECTRON MICROSCOPY (70 Å) | 主引用文献 | Molecular modeling of averaged rigor crossbridges from tomograms of insect flight muscle. J.Struct.Biol., 138, 2002
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6KUR
| Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B1) | 分子名称: | 3'-vRNA, 5'-vRNA, Polymerase 3, ... | 著者 | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | 登録日 | 2019-09-02 | 公開日 | 2019-10-02 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural insight into RNA synthesis by influenza D polymerase. Nat Microbiol, 4, 2019
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6KUK
| Structure of influenza D virus polymerase bound to vRNA promoter in mode A conformation (class A1) | 分子名称: | 3'-vRNA, 5'-vRNA, Polymerase 3, ... | 著者 | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | 登録日 | 2019-09-02 | 公開日 | 2019-10-02 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural insight into RNA synthesis by influenza D polymerase. Nat Microbiol, 4, 2019
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6KUP
| Structure of influenza D virus polymerase bound to vRNA promoter in Mode A conformation(Class A2) | 分子名称: | 3'-vRNA, 5'-vRNA, Polymerase 3, ... | 著者 | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | 登録日 | 2019-09-02 | 公開日 | 2019-10-02 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural insight into RNA synthesis by influenza D polymerase. Nat Microbiol, 4, 2019
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6KUV
| Structure of influenza D virus polymerase bound to cRNA promoter in class 2 | 分子名称: | 3'-cRNA, 5'-cRNA, Polymerase 3, ... | 著者 | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | 登録日 | 2019-09-02 | 公開日 | 2019-10-02 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural insight into RNA synthesis by influenza D polymerase. Nat Microbiol, 4, 2019
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6KUT
| Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B2) | 分子名称: | 3'-vRNA, 5'-vRNA, Polymerase 3, ... | 著者 | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | 登録日 | 2019-09-02 | 公開日 | 2019-10-02 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural insight into RNA synthesis by influenza D polymerase. Nat Microbiol, 4, 2019
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