5IE6

Crystal structure of a lactonase mutant in complex with substrate b

Summary for 5IE6

Entry DOI	10.2210/pdb5ie6/pdb
Related	5IE4 5IE5 5IE7
Descriptor	Zearalenone hydrolase, (3S,7S,11E)-7,14,16-trihydroxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclotetradecin-1-one (3 entities in total)
Functional Keywords	alpha/beta-hydrolase, lactonase, zearalenone, hydrolase
Biological source	Clonostachys rosea
Total number of polymer chains	3
Total formula weight	86928.64
Authors	Zheng, Y.Y.,Xu, Z.X.,Liu, W.D.,Chen, C.C.,Guo, R.T. (deposition date: 2016-02-25, release date: 2017-01-04, Last modification date: 2023-11-08)
Primary citation	Xu, Z.X.,Liu, W.D.,Chen, C.C.,Li, Q.,Huang, J.W.,Ko, T.P.,Liu, G.,Liu, W.,Peng, W.,Cheng, Y.S.,Chen, Y.,Jin, J.,Li, H.,Zheng, Y.Y.,Guo, R.T. Enhanced alph-Zearalenol Hydrolyzing Activity of a Mycoestrogen-Detoxifying Lactonase by Structure-Based Engineering Acs Catalysis, 6:7657-7663, 2016 Cited by DOI: 10.1021/acscatal.6b01826 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.67 Å)

Structure validation