Search by PDB author

Crystal structure of the SRCR domain of mouse SCARA5
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Scavenger receptor class A member 5
著者	Yu, B, He, Y.
登録日	2020-04-29
公開日	2020-09-16
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (2.501 Å)
主引用文献	Interactions of ferritin with scavenger receptor class A members. J.Biol.Chem., 295, 2020

8EPL

Human R-type voltage-gated calcium channel Cav2.3 at 3.1 Angstrom resolution
分子名称:	1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者	Gao, S, Yao, X, Yan, N.
登録日	2022-10-06
公開日	2022-12-14
最終更新日	2023-07-12
実験手法	ELECTRON MICROSCOPY (3.1 Å)
主引用文献	Structures of the R-type human Ca v 2.3 channel reveal conformational crosstalk of the intracellular segments. Nat Commun, 13, 2022

8EPM

Human R-type voltage-gated calcium channel Cav2.3 CH2II-deleted mutant at 3.1 Angstrom resolution
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者	Gao, S, Yao, X, Yan, N.
登録日	2022-10-06
公開日	2022-12-14
最終更新日	2023-07-12
実験手法	ELECTRON MICROSCOPY (3.1 Å)
主引用文献	Structures of the R-type human Ca v 2.3 channel reveal conformational crosstalk of the intracellular segments. Nat Commun, 13, 2022

3V3E

Crystal Structure of the Human Nur77 Ligand-binding Domain
分子名称:	GLYCEROL, Nuclear receptor subfamily 4 group A member 1
著者	Zhang, Q, Shi, C, Yang, K, Chen, Y, Zhan, Y, Wu, Q, Lin, T.
登録日	2011-12-13
公開日	2012-09-26
最終更新日	2023-11-08
実験手法	X-RAY DIFFRACTION (2.06 Å)
主引用文献	The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK Nat.Chem.Biol., 8, 2012

8K6Q

Crystal structure of HOIL-1L LTM domain
分子名称:	RanBP-type and C3HC4-type zinc finger-containing protein 1
著者	Yan, Z, Pan, L.F.
登録日	2023-07-25
公開日	2024-07-03
実験手法	X-RAY DIFFRACTION (1.59 Å)
主引用文献	Mechanistic insights into the homo-dimerization of HOIL-1L and SHARPIN. Biochem.Biophys.Res.Commun., 689, 2023

8DK7

Crystal structure of theophylline aptamer soaked with TAL2
分子名称:	FAB heavy chain, FAB light chain, RNA (34-MER)
著者	Menichelli, E, Spraggon, G.
登録日	2022-07-04
公開日	2022-11-30
最終更新日	2023-10-25
実験手法	X-RAY DIFFRACTION (2.46 Å)
主引用文献	Discovery of small molecules that target a tertiary-structured RNA. Proc.Natl.Acad.Sci.USA, 119, 2022

8D28

Crystal structure of theophylline aptamer in complex with theophylline
分子名称:	MAGNESIUM ION, RNA (33-MER), SODIUM ION, ...
著者	Menichelli, E, Spraggon, G.
登録日	2022-05-28
公開日	2022-11-30
最終更新日	2023-10-25
実験手法	X-RAY DIFFRACTION (1.42 Å)
主引用文献	Discovery of small molecules that target a tertiary-structured RNA. Proc.Natl.Acad.Sci.USA, 119, 2022

8D2B

Crystal structure of theophylline aptamer in complex with TAL2
分子名称:	6-methoxy-7-[3-(piperidin-1-yl)propoxy]quinazolin-4-ol, MAGNESIUM ION, RNA (33-MER), ...
著者	Menichelli, E, Spraggon, G.
登録日	2022-05-28
公開日	2022-11-30
最終更新日	2023-10-25
実験手法	X-RAY DIFFRACTION (1.44 Å)
主引用文献	Discovery of small molecules that target a tertiary-structured RNA. Proc.Natl.Acad.Sci.USA, 119, 2022

8D2A

Crystal structure of theophylline aptamer in complex with TAL3
分子名称:	6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-ol, MAGNESIUM ION, RNA (33-MER), ...
著者	Menichelli, E, Spraggon, G.
登録日	2022-05-28
公開日	2022-11-30
最終更新日	2023-10-25
実験手法	X-RAY DIFFRACTION (2.17 Å)
主引用文献	Discovery of small molecules that target a tertiary-structured RNA. Proc.Natl.Acad.Sci.USA, 119, 2022

8D5L

Crystal structure of theophylline aptamer in complex with TAL1
分子名称:	4-amino-8-methylpteridine-2,7(1H,8H)-dione, CALCIUM ION, MAGNESIUM ION, ...
著者	Menichelli, E, Spraggon, G.
登録日	2022-06-05
公開日	2022-11-30
最終更新日	2023-10-25
実験手法	X-RAY DIFFRACTION (1.64 Å)
主引用文献	Discovery of small molecules that target a tertiary-structured RNA. Proc.Natl.Acad.Sci.USA, 119, 2022

8D5O

Crystal structure of theophylline aptamer in complex with TAL4
分子名称:	4-[4-(6,7-dimethoxyquinazolin-4-yl)piperazin-1-yl]butan-1-ol, RNA (33-MER)
著者	Menichelli, E, Spraggon, G.
登録日	2022-06-05
公開日	2022-11-30
最終更新日	2023-10-25
実験手法	X-RAY DIFFRACTION (2.7 Å)
主引用文献	Discovery of small molecules that target a tertiary-structured RNA. Proc.Natl.Acad.Sci.USA, 119, 2022

8D29

Crystal structure of theophylline aptamer - apo form
分子名称:	Fab heavy chain, Fab light chain, POTASSIUM ION, ...
著者	Menichelli, E, Spraggon, G.
登録日	2022-05-28
公開日	2022-11-30
最終更新日	2023-10-25
実験手法	X-RAY DIFFRACTION (1.81 Å)
主引用文献	Discovery of small molecules that target a tertiary-structured RNA. Proc.Natl.Acad.Sci.USA, 119, 2022

8K6P

Crystal structure of SHARPIN LTM motif
分子名称:	Sharpin
著者	Yan, Z, Pan, L.F.
登録日	2023-07-25
公開日	2024-07-03
実験手法	X-RAY DIFFRACTION (1.86 Å)
主引用文献	Mechanistic insights into the homo-dimerization of HOIL-1L and SHARPIN. Biochem.Biophys.Res.Commun., 689, 2023

3V3Q

Crystal Structure of Human Nur77 Ligand-binding Domain in Complex with Ethyl 2-[2,3,4 trimethoxy-6(1-octanoyl)phenyl]acetate
分子名称:	GLYCEROL, Nuclear receptor subfamily 4 group A member 1, SODIUM ION, ...
著者	Zhang, Q, Shi, C, Yang, K, Chen, Y, Zhan, Y, Wu, Q, Lin, T.
登録日	2011-12-14
公開日	2012-09-26
最終更新日	2023-11-08
実験手法	X-RAY DIFFRACTION (2.22 Å)
主引用文献	The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK Nat.Chem.Biol., 8, 2012

7L3N

SARS-CoV 2 Spike Protein bound to LY-CoV555
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LY-CoV555 Fab heavy chain, ...
著者	Goldsmith, J.A, McLellan, J.S.
登録日	2020-12-18
公開日	2021-02-03
実験手法	ELECTRON MICROSCOPY (3.27 Å)
主引用文献	LY-CoV555, a rapidly isolated potent neutralizing antibody, provides protection in a non-human primate model of SARS-CoV-2 infection. Biorxiv, 2020

4TVZ

Crystal Structure of SCARB2 in Neural Condition (pH7.5)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Scavenger receptor class B member 2, ...
著者	Dang, M.H, Wang, X.X, Rao, Z.H.
登録日	2014-06-29
公開日	2015-07-08
最終更新日	2023-11-08
実験手法	X-RAY DIFFRACTION (3.006 Å)
主引用文献	Molecular mechanism of SCARB2-mediated attachment and uncoating of EV71 Protein Cell, 5, 2014

6JV3

Crystal structure of 5-hydoxylmethylcytosine containing decamer dsDNA
分子名称:	DNA (5'-D(CPCPAPGP(5HC)PGPCPTPGPG)-3')
著者	Zhang, L, Wang, Y.X.
登録日	2019-04-15
公開日	2019-07-31
最終更新日	2024-03-27
実験手法	X-RAY DIFFRACTION (2.851 Å)
主引用文献	Thymine DNA glycosylase recognizes the geometry alteration of minor grooves induced by 5-formylcytosine and 5-carboxylcytosine. Chem Sci, 10, 2019

6JV5

Crystal structure of 5-methylcytosine containing decamer dsDNA
分子名称:	DNA (5'-D(CPCPAPGP(5CM)PGPCPTPGPG)-3')
著者	Zhang, L, Wang, Y.X.
登録日	2019-04-15
公開日	2019-07-31
最終更新日	2024-03-27
実験手法	X-RAY DIFFRACTION (1.401 Å)
主引用文献	Thymine DNA glycosylase recognizes the geometry alteration of minor grooves induced by 5-formylcytosine and 5-carboxylcytosine. Chem Sci, 10, 2019

5F5M

Crystal structure of Marburg virus nucleoprotein core domain
分子名称:	Nucleoprotein
著者	Guo, Y, Liu, B.C, Liu, X, Li, G.B, Wang, W.M, Dong, S.S, Wang, W.J.
登録日	2015-12-04
公開日	2017-05-31
最終更新日	2024-03-20
実験手法	X-RAY DIFFRACTION (2.902 Å)
主引用文献	Structural Insight into Nucleoprotein Conformation Change Chaperoned by VP35 Peptide in Marburg Virus J. Virol., 91, 2017

7JMN

Tail module of Mediator complex
分子名称:	MED15, Mediator of RNA polymerase II transcription subunit 14, Mediator of RNA polymerase II transcription subunit 16, ...
著者	Zhang, H.Q, Chen, D.C.
登録日	2020-08-02
公開日	2021-03-03
最終更新日	2024-03-06
実験手法	ELECTRON MICROSCOPY (3.58 Å)
主引用文献	Mediator structure and conformation change. Mol.Cell, 81, 2021

5F5O

Crystal structure of Marburg virus nucleoprotein core domain bound to VP35 regulation peptide
分子名称:	Nucleoprotein, Peptide from Polymerase cofactor VP35, SULFATE ION
著者	Guo, Y, Liu, B.C, Liu, X, Li, G.B, Wang, W.M, Dong, S.S, Wang, W.J.
登録日	2015-12-04
公開日	2017-05-31
最終更新日	2024-03-20
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Structural Insight into Nucleoprotein Conformation Change Chaperoned by VP35 Peptide in Marburg Virus J. Virol., 91, 2017

5BPE

Crystal structure of EV71 3Cpro in complex with a potent and selective Inhibitor
分子名称:	(2~{S})-~{N}-[(1~{R},2~{S})-1-cyano-1-oxidanyl-3-[(3~{S})-2-oxidanylidenepiperidin-3-yl]propan-2-yl]-3-phenyl-2-[[(~{E})-3-phenylprop-2-enoyl]amino]propanamide, EV71 3Cpro
著者	Luqing, S, Yin, Z.
登録日	2015-05-28
公開日	2015-11-25
最終更新日	2024-03-20
実験手法	X-RAY DIFFRACTION (2.7 Å)
主引用文献	Cyanohydrin as an Anchoring Group for Potent and Selective Inhibitors of Enterovirus 71 3C Protease J.Med.Chem., 58, 2015

4LN0

Crystal structure of the VGLL4-TEAD4 complex
分子名称:	DI(HYDROXYETHYL)ETHER, GLYCEROL, Transcription cofactor vestigial-like protein 4, ...
著者	Wang, H, Shi, Z, Zhou, Z.
登録日	2013-07-11
公開日	2014-02-26
最終更新日	2023-11-08
実験手法	X-RAY DIFFRACTION (2.896 Å)
主引用文献	A Peptide Mimicking VGLL4 Function Acts as a YAP Antagonist Therapy against Gastric Cancer. Cancer Cell, 25, 2014

4QR3

Brd4 Bromodomain 1 complex with its novel inhibitors
分子名称:	Bromodomain-containing protein 4, N-cyclopentyl-3-(2-oxo-2,3-dihydro-1,3-thiazol-4-yl)benzenesulfonamide
著者	Xiong, B, Cao, D.Y, Chen, T.T, Xu, Y.C.
登録日	2014-06-30
公開日	2015-07-01
最終更新日	2024-03-20
実験手法	X-RAY DIFFRACTION (1.374 Å)
主引用文献	Fragment-based drug discovery of 2-thiazolidinones as BRD4 inhibitors: 2. Structure-based optimization J.Med.Chem., 58, 2015

4QR4

Brd4 Bromodomain 1 complex with its novel inhibitors
分子名称:	2-chloro-N-cyclopentyl-5-(2-oxo-2,3-dihydro-1,3-thiazol-4-yl)benzenesulfonamide, Bromodomain-containing protein 4
著者	Xiong, B, Cao, D.Y, Chen, T.T, Xu, Y.C.
登録日	2014-06-30
公開日	2015-07-01
最終更新日	2024-03-20
実験手法	X-RAY DIFFRACTION (1.28 Å)
主引用文献	Fragment-based drug discovery of 2-thiazolidinones as BRD4 inhibitors: 2. Structure-based optimization J.Med.Chem., 58, 2015

<45 46 47 48 49 50 515253 54 55 56 57 58 59 60 >

全ヒット件数:	2781
表示件数:	25
表示順	関連性が高い順