8D5L
Crystal structure of theophylline aptamer in complex with TAL1
Summary for 8D5L
Entry DOI | 10.2210/pdb8d5l/pdb |
Descriptor | RNA (33-MER), 4-amino-8-methylpteridine-2,7(1H,8H)-dione, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | rna, aptamer, theophylline |
Biological source | synthetic construct |
Total number of polymer chains | 4 |
Total formula weight | 43760.54 |
Authors | Menichelli, E.,Spraggon, G. (deposition date: 2022-06-05, release date: 2022-11-30, Last modification date: 2023-10-25) |
Primary citation | Menichelli, E.,Lam, B.J.,Wang, Y.,Wang, V.S.,Shaffer, J.,Tjhung, K.F.,Bursulaya, B.,Nguyen, T.N.,Vo, T.,Alper, P.B.,McAllister, C.S.,Jones, D.H.,Spraggon, G.,Michellys, P.Y.,Joslin, J.,Joyce, G.F.,Rogers, J. Discovery of small molecules that target a tertiary-structured RNA. Proc.Natl.Acad.Sci.USA, 119:e2213117119-e2213117119, 2022 Cited by PubMed: 36413497DOI: 10.1073/pnas.2213117119 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.64 Å) |
Structure validation
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