8GQU
| AK-42 inhibitor binding human ClC-2 TMD | 分子名称: | 2-[[2,6-bis(chloranyl)-3-phenylmethoxy-phenyl]amino]pyridine-3-carboxylic acid, Chloride channel protein 2 | 著者 | Wang, L. | 登録日 | 2022-08-30 | 公開日 | 2023-07-05 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42. Nat Commun, 14, 2023
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8DMH
| Lymphocytic choriomeningitis virus glycoprotein in complex with neutralizing antibody M28 | 分子名称: | 18.5C-M28 Fab Heavy Chain, 18.5C-M28 Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Moon-Walker, A, Hastie, K.M, Zyla, D.S, Saphire, E.O. | 登録日 | 2022-07-08 | 公開日 | 2023-04-12 | 最終更新日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | 主引用文献 | Structural basis for antibody-mediated neutralization of lymphocytic choriomeningitis virus. Cell Chem Biol, 30, 2023
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8DMI
| Lymphocytic choriomeningitis virus glycoprotein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein G1, ... | 著者 | Moon-Walker, A, Hastie, K.M, Zyla, D.S, Saphire, E.O. | 登録日 | 2022-07-08 | 公開日 | 2023-04-12 | 最終更新日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | Structural basis for antibody-mediated neutralization of lymphocytic choriomeningitis virus. Cell Chem Biol, 30, 2023
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5I7E
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3CCB
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8DSV
| The structure of NicA2 in complex with N-methylmyosmine | 分子名称: | DI(HYDROXYETHYL)ETHER, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, FAD-dependent oxidoreductase, ... | 著者 | Wu, K, Dulchavsky, M, Li, J, Bardwell, J.C.A. | 登録日 | 2022-07-22 | 公開日 | 2023-07-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Directed evolution unlocks oxygen reactivity for a nicotine-degrading flavoenzyme. Nat.Chem.Biol., 19, 2023
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8DQ8
| The structure of NicA2 variant F104L/A107T/S146I/G317D/H368R/L449V/N462S in complex with N-methylmyosmine | 分子名称: | (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, 1,2-ETHANEDIOL, Amine oxidase, ... | 著者 | Wu, K, Dulchavsky, M, Li, J, Bardwell, J.C.A. | 登録日 | 2022-07-18 | 公開日 | 2023-07-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Directed evolution unlocks oxygen reactivity for a nicotine-degrading flavoenzyme. Nat.Chem.Biol., 19, 2023
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3C6A
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8DQ7
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5J5A
| Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor (Chem 70786556) | 分子名称: | METHIONINE, Methionyl-tRNA synthetase, putative, ... | 著者 | Barros-Alvarez, X, Koh, C.Y, Hol, W.G.J. | 登録日 | 2016-04-01 | 公開日 | 2017-01-25 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure-guided design of novel Trypanosoma brucei Methionyl-tRNA synthetase inhibitors. Eur J Med Chem, 124, 2016
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5J58
| Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor (Chem 1856) | 分子名称: | (3S)-1-(5-chloro-1H-imidazo[4,5-b]pyridin-2-yl)-N-[(3,5-dichlorophenyl)methyl]piperidin-3-amine, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Barros-Alvarez, X, Hol, W.G.J. | 登録日 | 2016-04-01 | 公開日 | 2017-01-25 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure-guided design of novel Trypanosoma brucei Methionyl-tRNA synthetase inhibitors. Eur J Med Chem, 124, 2016
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3HH0
| Crystal structure of a transcriptional regulator, MerR family from Bacillus cereus | 分子名称: | Transcriptional regulator, MerR family | 著者 | Palani, K, Zhang, Z, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2009-05-14 | 公開日 | 2009-05-26 | 最終更新日 | 2021-02-10 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Crystal structure of a transcriptional regulator, MerR family from Bacillus cereus To be Published
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5K0T
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3DWR
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8EKY
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8EKW
| Cryo-EM structure of human PRDX4 | 分子名称: | Peroxiredoxin-4 | 著者 | Su, C.C. | 登録日 | 2022-09-22 | 公開日 | 2023-05-03 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | High-resolution structural-omics of human liver enzymes. Cell Rep, 42, 2023
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8EM2
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3CCC
| Crystal Structure of Human DPP4 in complex with a benzimidazole derivative | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-(aminomethyl)-6-(2-chlorophenyl)-1-methyl-1H-benzimidazole-5-carbonitrile, ... | 著者 | Wallace, M.B, Skene, R.J. | 登録日 | 2008-02-25 | 公開日 | 2008-10-21 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Structure-based design and synthesis of benzimidazole derivatives as dipeptidyl peptidase IV inhibitors. Bioorg.Med.Chem.Lett., 18, 2008
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5J59
| Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor (Chem 1893) | 分子名称: | 5-chloro-N-(2-{[(3,5-dichlorophenyl)methyl]amino}ethyl)-N-methyl-3H-imidazo[4,5-b]pyridin-2-amine, GLYCEROL, METHIONINE, ... | 著者 | Barros-Alvarez, X, Hol, W.G.J. | 登録日 | 2016-04-01 | 公開日 | 2017-01-25 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure-guided design of novel Trypanosoma brucei Methionyl-tRNA synthetase inhibitors. Eur J Med Chem, 124, 2016
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3UQG
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3UPZ
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3V5T
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8FXF
| Crystal structure of the coiled-coil domain of TRIM56 | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, E3 ubiquitin-protein ligase TRIM56 | 著者 | Lou, X.H, Ma, B.B, Zhuang, Y, Li, X.C. | 登録日 | 2023-01-24 | 公開日 | 2023-05-24 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | TRIM56 coiled-coil domain structure provides insights into its E3 ligase functions. Comput Struct Biotechnol J, 21, 2023
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3V51
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3V5P
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