6WKN
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![BU of 6wkn by Molmil](/molmil-images/mine/6wkn) | PL-bound rat TRPV2 in nanodiscs | 分子名称: | Transient receptor potential cation channel subfamily V member 2, piperlongumine | 著者 | Pumroy, R.P, Moiseenkova-Bell, V.Y. | 登録日 | 2020-04-16 | 公開日 | 2021-04-21 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | 主引用文献 | Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression. Acs Cent.Sci., 7, 2021
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6BJF
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![BU of 6bjf by Molmil](/molmil-images/mine/6bjf) | NMR Structural and biophysical functional analysis of intracellular loop 5 of the NHE1 isoform of the Na+/H+ exchanger. | 分子名称: | GLY-LEU-THR-TRP-PHE-ILE-ASN-LYS-PHE-ARG-ILE-VAL-LYS | 著者 | McKay, R, Wong, K, Towle, K, Fliegel, L. | 登録日 | 2017-11-06 | 公開日 | 2018-11-14 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Diverse residues of intracellular loop 5 of the Na+/H+exchanger modulate proton sensing, expression, activity and targeting. Biochim Biophys Acta Biomembr, 1861, 2019
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5GWN
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7FBD
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![BU of 7fbd by Molmil](/molmil-images/mine/7fbd) | De novo design protein D53 with MBP tag | 分子名称: | Maltodextrin-binding protein,De novo design protein D53 | 著者 | Bin, H. | 登録日 | 2021-07-09 | 公開日 | 2021-12-22 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | A backbone-centred energy function of neural networks for protein design. Nature, 602, 2022
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7FBB
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![BU of 7fbb by Molmil](/molmil-images/mine/7fbb) | De novo design protein D12 with MBP tag | 分子名称: | Maltodextrin-binding protein,de novo designed protein D12 | 著者 | Bin, H. | 登録日 | 2021-07-09 | 公開日 | 2021-12-22 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.307 Å) | 主引用文献 | A backbone-centred energy function of neural networks for protein design. Nature, 602, 2022
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7FBC
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![BU of 7fbc by Molmil](/molmil-images/mine/7fbc) | De novo design protein D22 with MBP tag | 分子名称: | Maltodextrin-binding protein,De novo design protein D22 | 著者 | Bin, H. | 登録日 | 2021-07-09 | 公開日 | 2021-12-22 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | A backbone-centred energy function of neural networks for protein design. Nature, 602, 2022
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3W53
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3O7Q
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![BU of 3o7q by Molmil](/molmil-images/mine/3o7q) | Crystal structure of a Major Facilitator Superfamily (MFS) transporter, FucP, in the outward conformation | 分子名称: | L-fucose-proton symporter, nonyl beta-D-glucopyranoside | 著者 | Sun, L.F, Dang, S.Y, Wang, J, Yan, N. | 登録日 | 2010-07-30 | 公開日 | 2010-09-15 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.143 Å) | 主引用文献 | Structure of a fucose transporter in an outward-open conformation Nature, 467, 2010
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4NSD
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![BU of 4nsd by Molmil](/molmil-images/mine/4nsd) | Crystal Structure of CBARA1 in the Ca2+ Binding Form | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, CHLORIDE ION, ... | 著者 | Wang, L, Yang, X, Li, S, Shen, Y. | 登録日 | 2013-11-28 | 公開日 | 2014-02-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural and mechanistic insights into MICU1 regulation of mitochondrial calcium uptake. Embo J., 33, 2014
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8R8A
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5XUP
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![BU of 5xup by Molmil](/molmil-images/mine/5xup) | Crystal structure of TRF1 and TERB1 | 分子名称: | Telomere repeats-binding bouquet formation protein 1, Telomeric repeat-binding factor 1 | 著者 | Long, J, Huang, C, Wu, J, Lei, M. | 登録日 | 2017-06-24 | 公開日 | 2017-11-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Telomeric TERB1-TRF1 interaction is crucial for male meiosis. Nat. Struct. Mol. Biol., 24, 2017
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8R8C
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6IXM
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![BU of 6ixm by Molmil](/molmil-images/mine/6ixm) | Crystal structure of the ketone reductase ChKRED20 from the genome of Chryseobacterium sp. CA49 complexed with NAD | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Short-chain dehydrogenase reductase | 著者 | Zhao, F.J, Jin, Y, Liu, Z.C, Wang, G.G, Wu, Z.L. | 登録日 | 2018-12-11 | 公開日 | 2019-04-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | 主引用文献 | Structure-guided engineering of ChKRED20 from Chryseobacterium sp. CA49 for asymmetric reduction of aryl ketoesters. Enzyme Microb. Technol., 125, 2019
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5GTM
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![BU of 5gtm by Molmil](/molmil-images/mine/5gtm) | Modified human MxA, nucleotide-free form | 分子名称: | Interferon-induced GTP-binding protein Mx1 | 著者 | Chen, Y, Gao, S. | 登録日 | 2016-08-22 | 公開日 | 2017-05-31 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.896 Å) | 主引用文献 | Conformational dynamics of dynamin-like MxA revealed by single-molecule FRET Nat Commun, 8, 2017
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3LMG
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8IZL
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1ZVS
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![BU of 1zvs by Molmil](/molmil-images/mine/1zvs) | Crystal structure of the first class MHC mamu and Tat-Tl8 complex | 分子名称: | Beta-2-microglobulin, MHC class I antigen, Tat-Tl8 | 著者 | Lou, Z, Chu, F, Gao, G.F, Rao, Z. | 登録日 | 2005-06-02 | 公開日 | 2006-06-13 | 最終更新日 | 2019-11-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | First glimpse of the peptide presentation by rhesus macaque MHC class I: crystal structures of Mamu-A*01 complexed with two immunogenic SIV epitopes and insights into CTL escape. J Immunol., 178, 2007
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4K9B
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![BU of 4k9b by Molmil](/molmil-images/mine/4k9b) | Structure of Ternary Complex of cGAS with dsDNA and Bound c[G(2 ,5 )pA(3 ,5 )p] | 分子名称: | ADENOSINE MONOPHOSPHATE, Cyclic GMP-AMP synthase, DNA-F, ... | 著者 | Gao, P, Wu, Y, Patel, D.J. | 登録日 | 2013-04-19 | 公開日 | 2013-05-15 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell(Cambridge,Mass.), 153, 2013
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4K96
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![BU of 4k96 by Molmil](/molmil-images/mine/4k96) | Structure of Binary Complex of cGAS with Bound dsDNA | 分子名称: | Cyclic GMP-AMP synthase, DNA-F, DNA-R, ... | 著者 | Gao, P, Wu, Y, Patel, D.J. | 登録日 | 2013-04-19 | 公開日 | 2013-05-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.084 Å) | 主引用文献 | Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell(Cambridge,Mass.), 153, 2013
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4K98
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![BU of 4k98 by Molmil](/molmil-images/mine/4k98) | Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppG(2 ,5 )pG | 分子名称: | Cyclic GMP-AMP synthase, DNA-F, DNA-R, ... | 著者 | Gao, P, Wu, Y, Patel, D.J. | 登録日 | 2013-04-19 | 公開日 | 2013-05-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell(Cambridge,Mass.), 153, 2013
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8JOP
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![BU of 8jop by Molmil](/molmil-images/mine/8jop) | Crystal structure of the SARS-CoV-2 main protease in complex with 11a | 分子名称: | 3C-like proteinase nsp5, methyl (6~{R})-5-ethanoyl-7-oxidanylidene-6-[4-(trifluoromethyl)phenyl]-8,9,10,11-tetrahydro-6~{H}-benzo[b][1,4]benzodiazepine-2-carboxylate | 著者 | Zeng, R, Liu, Y.Z, Wang, F.L, Yang, S.Y, Lei, J. | 登録日 | 2023-06-08 | 公開日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Discovery of benzodiazepine derivatives as a new class of covalent inhibitors of SARS-CoV-2 main protease. Bioorg.Med.Chem.Lett., 92, 2023
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4K8V
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![BU of 4k8v by Molmil](/molmil-images/mine/4k8v) | Structure of cyclic GMP-AMP Synthase (cGAS) | 分子名称: | Cyclic GMP-AMP synthase, ZINC ION | 著者 | Gao, P, Wu, Y, Patel, D.J. | 登録日 | 2013-04-18 | 公開日 | 2013-05-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell(Cambridge,Mass.), 153, 2013
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4K1I
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![BU of 4k1i by Molmil](/molmil-images/mine/4k1i) | Induced opening of influenza virus neuraminidase N2 150-loop suggests an important role in inhibitor binding | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Wu, Y, Gao, F, Qi, J.X, Gao, G.F. | 登録日 | 2013-04-05 | 公開日 | 2013-06-05 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Induced opening of influenza virus neuraminidase N2 150-loop suggests an important role in inhibitor binding Sci Rep, 3, 2013
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7C7E
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![BU of 7c7e by Molmil](/molmil-images/mine/7c7e) | Crystal structure of C terminal domain of Escherichia coli DgoR | 分子名称: | Putative DNA-binding transcriptional regulator, SULFATE ION, TRIETHYLENE GLYCOL, ... | 著者 | Lin, W. | 登録日 | 2020-05-25 | 公開日 | 2021-01-20 | 実験手法 | X-RAY DIFFRACTION (2.047 Å) | 主引用文献 | Structural and Functional Analyses of the Transcription Repressor DgoR From Escherichia coli Reveal a Divalent Metal-Containing D-Galactonate Binding Pocket. Front Microbiol, 11, 2020
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4NSC
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![BU of 4nsc by Molmil](/molmil-images/mine/4nsc) | Crystal Structure of CBARA1 in the Apo-form | 分子名称: | Calcium uptake protein 1, mitochondrial | 著者 | Wang, L, Yang, X, Li, S, Shen, Y. | 登録日 | 2013-11-28 | 公開日 | 2014-02-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural and mechanistic insights into MICU1 regulation of mitochondrial calcium uptake. Embo J., 33, 2014
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