Crystal structure of the ketone reductase ChKRED20 from the genome of Chryseobacterium sp. CA49 complexed with NAD

Summary for 6IXM

DescriptorShort-chain dehydrogenase reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total)
Functional Keywordsoxidoreductase
Biological sourceChryseobacterium sp. CA49
Total number of polymer chains4
Total molecular weight107025.46
Zhao, F.J.,Jin, Y.,Liu, Z.C.,Wang, G.G.,Wu, Z.L. (deposition date: 2018-12-11, release date: 2019-04-03)
Primary citation
Li, T.B.,Zhao, F.J.,Liu, Z.,Jin, Y.,Liu, Y.,Pei, X.Q.,Zhang, Z.G.,Wang, G.,Wu, Z.L.
Structure-guided engineering of ChKRED20 from Chryseobacterium sp. CA49 for asymmetric reduction of aryl ketoesters.
Enzyme Microb. Technol., 125:29-36, 2019
PubMed: 30885322 (PDB entries with the same primary citation)
DOI: 10.1016/j.enzmictec.2019.03.001
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.19120 0.7% 1.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution